BR0212299A - Formulações tixotrópicas oleosas - Google Patents
Formulações tixotrópicas oleosasInfo
- Publication number
- BR0212299A BR0212299A BR0212299-5A BR0212299A BR0212299A BR 0212299 A BR0212299 A BR 0212299A BR 0212299 A BR0212299 A BR 0212299A BR 0212299 A BR0212299 A BR 0212299A
- Authority
- BR
- Brazil
- Prior art keywords
- hydrophilic polymer
- oily
- relates
- oily thixotropic
- formulations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/485—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Cosmetics (AREA)
Abstract
"FORMULAçõES TIXOTRóPICAS OLEOSAS". A presente invenção refere-se a um novo veículo tixotrópico oleoso contendo de 0,2 % a 5 % (p/p) de uma sílica coloidal e de 0,2 % a 5 % (p/p) de um polímero hidrofílico em um óleo comestível. A interação entre o polímero hidrofílico e o dióxido de silício coloidal nas faixas de concentração acima permite manter o montante do último componente em uma concentração mais baixa, conferindo, apesar disso, à solução tixotropia suficiente e uma baixa viscosidade em cisalhamento. A invenção também refere-se a cápsulas cheias com a massa de enchimento acima.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01121545 | 2001-09-10 | ||
| PCT/EP2002/009770 WO2003022254A1 (en) | 2001-09-10 | 2002-09-02 | Oily thixotropic formulations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR0212299A true BR0212299A (pt) | 2004-09-14 |
| BRPI0212299B1 BRPI0212299B1 (pt) | 2016-03-15 |
Family
ID=8178591
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0212299A BRPI0212299B1 (pt) | 2001-09-10 | 2002-09-02 | veículo tixotrópico oleoso, seu processo de preparação, massa de enchimento, e dose unitária farmacêutica |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US20030054043A1 (pt) |
| EP (1) | EP1427397B1 (pt) |
| JP (1) | JP4105091B2 (pt) |
| KR (1) | KR100598871B1 (pt) |
| CN (1) | CN1275592C (pt) |
| AR (1) | AR036433A1 (pt) |
| AT (1) | ATE385785T1 (pt) |
| AU (1) | AU2002340847B2 (pt) |
| BR (1) | BRPI0212299B1 (pt) |
| CA (1) | CA2457250C (pt) |
| DE (1) | DE60225026T2 (pt) |
| DK (1) | DK1427397T3 (pt) |
| ES (1) | ES2299604T3 (pt) |
| MX (1) | MXPA04002220A (pt) |
| PL (1) | PL202691B1 (pt) |
| PT (1) | PT1427397E (pt) |
| RU (1) | RU2302233C2 (pt) |
| WO (1) | WO2003022254A1 (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2009001228A (es) * | 2006-08-03 | 2009-02-11 | Unilever Nv | Composicion para cuidado oral. |
| DE102007055341A1 (de) | 2007-11-19 | 2009-05-20 | Bayer Animal Health Gmbh | Stabilisierung öliger Suspensionen enthaltend hydrophobe Kieselsäuren |
| US20160331695A1 (en) * | 2014-01-31 | 2016-11-17 | Fuji Capsule Co., Ltd. | Capsule Formulation |
| JP6874276B2 (ja) * | 2016-04-19 | 2021-05-19 | 昭和電工マテリアルズ株式会社 | 分離材及びカラム |
| DE102018122533A1 (de) * | 2018-09-14 | 2020-03-19 | Institut Dr. Rilling Healthcare Gmbh | Brenn- und essbare Zusammensetzung aus mittelkettigen Trigliceriden und Kieselsäure |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1572226A (en) * | 1977-11-03 | 1980-07-30 | Hoechst Uk Ltd | Pharmaceutical preparations in solid unit dosage form |
| GB1590864A (en) * | 1978-05-16 | 1981-06-10 | Lilly Industries Ltd | Thixotropic filling medium for hard gelatin capsules |
| US4291015A (en) * | 1979-08-14 | 1981-09-22 | Key Pharmaceuticals, Inc. | Polymeric diffusion matrix containing a vasodilator |
| DE3124983A1 (de) * | 1981-06-25 | 1983-01-20 | Meditest Inst Fuer Medizinisch | Arzneiformen zur oralen verabreichung |
| YU44680B (en) * | 1982-07-30 | 1990-12-31 | Glaxo Lab Ltd | Process for obtaining very pure amorphous form of cephuroxim axetile |
| DE3333639A1 (de) * | 1983-09-17 | 1985-03-28 | Dynamit Nobel Ag | Zubereitung von nitroestern fuer die koronartherapie |
| US5288500A (en) * | 1987-03-13 | 1994-02-22 | Benzon Pharma A/S | Oral composition containing particles comprising an active substance |
| JPH03176419A (ja) * | 1989-12-05 | 1991-07-31 | Asahi Chem Ind Co Ltd | チキソトロピー性付与坐剤 |
| US5665384A (en) * | 1990-04-06 | 1997-09-09 | Rhone-Poulenc Rorer S.A. | Oily capsules of ketoprofen |
| FR2660555B1 (fr) * | 1990-04-06 | 1994-09-16 | Rhone Poulenc Sante | Gelule huileuse de ketoprofene. |
| US5192572A (en) * | 1991-03-25 | 1993-03-09 | The Procter & Gamble Company | Method of using silica to decrease fat absorption |
| US5362504A (en) * | 1992-06-23 | 1994-11-08 | General Mills, Inc. | Edible microwave susceptor composition |
| US5989586A (en) * | 1992-10-05 | 1999-11-23 | Cygnus, Inc. | Two-phase matrix for sustained release drug delivery device |
| GB9405304D0 (en) * | 1994-03-16 | 1994-04-27 | Scherer Ltd R P | Delivery systems for hydrophobic drugs |
| FR2781373B1 (fr) * | 1998-07-07 | 2001-09-21 | Pf Medicament | Formulations thixotropes pour le remplissage de gelules |
| WO2000033866A1 (en) * | 1998-12-04 | 2000-06-15 | Provalis Uk Limited | Pharmaceutical compositions containing insulin |
| DK1035115T3 (da) * | 1999-02-24 | 2005-01-24 | Hoffmann La Roche | 4-phenylpyridinderivater og anvendelse deraf som NK-1-receptorantagonister |
| FR2790200B3 (fr) * | 1999-02-26 | 2001-06-01 | Sanofi Sa | Formulation stable contenant de la fumagilline |
| ATE361757T1 (de) * | 1999-02-26 | 2007-06-15 | Sanofi Aventis | Stabile fumagillin-formulierung |
-
2002
- 2002-09-02 EP EP02774546A patent/EP1427397B1/en not_active Expired - Lifetime
- 2002-09-02 KR KR1020047003491A patent/KR100598871B1/ko active IP Right Grant
- 2002-09-02 JP JP2003526384A patent/JP4105091B2/ja not_active Expired - Fee Related
- 2002-09-02 PL PL367709A patent/PL202691B1/pl unknown
- 2002-09-02 DK DK02774546T patent/DK1427397T3/da active
- 2002-09-02 AU AU2002340847A patent/AU2002340847B2/en not_active Ceased
- 2002-09-02 PT PT02774546T patent/PT1427397E/pt unknown
- 2002-09-02 ES ES02774546T patent/ES2299604T3/es not_active Expired - Lifetime
- 2002-09-02 BR BRPI0212299A patent/BRPI0212299B1/pt not_active IP Right Cessation
- 2002-09-02 AT AT02774546T patent/ATE385785T1/de active
- 2002-09-02 MX MXPA04002220A patent/MXPA04002220A/es active IP Right Grant
- 2002-09-02 CN CNB028173171A patent/CN1275592C/zh not_active Expired - Lifetime
- 2002-09-02 CA CA2457250A patent/CA2457250C/en not_active Expired - Fee Related
- 2002-09-02 RU RU2004111009/15A patent/RU2302233C2/ru not_active IP Right Cessation
- 2002-09-02 WO PCT/EP2002/009770 patent/WO2003022254A1/en active IP Right Grant
- 2002-09-02 DE DE60225026T patent/DE60225026T2/de not_active Expired - Lifetime
- 2002-09-04 US US10/234,722 patent/US20030054043A1/en not_active Abandoned
- 2002-09-06 AR ARP020103363A patent/AR036433A1/es unknown
-
2009
- 2009-02-18 US US12/372,764 patent/US20090155356A1/en not_active Abandoned
-
2012
- 2012-02-03 US US13/365,284 patent/US20120141582A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| PL202691B1 (pl) | 2009-07-31 |
| CN1275592C (zh) | 2006-09-20 |
| RU2004111009A (ru) | 2005-08-10 |
| ES2299604T3 (es) | 2008-06-01 |
| ATE385785T1 (de) | 2008-03-15 |
| US20090155356A1 (en) | 2009-06-18 |
| US20030054043A1 (en) | 2003-03-20 |
| US20120141582A1 (en) | 2012-06-07 |
| KR20040039341A (ko) | 2004-05-10 |
| CA2457250C (en) | 2010-03-30 |
| JP4105091B2 (ja) | 2008-06-18 |
| AU2002340847B2 (en) | 2007-09-13 |
| WO2003022254A1 (en) | 2003-03-20 |
| EP1427397A1 (en) | 2004-06-16 |
| DE60225026T2 (de) | 2009-02-05 |
| PT1427397E (pt) | 2008-03-24 |
| JP2005501914A (ja) | 2005-01-20 |
| KR100598871B1 (ko) | 2006-07-12 |
| DK1427397T3 (da) | 2008-05-26 |
| EP1427397B1 (en) | 2008-02-13 |
| CA2457250A1 (en) | 2003-03-20 |
| CN1551759A (zh) | 2004-12-01 |
| AR036433A1 (es) | 2004-09-08 |
| PL367709A1 (en) | 2005-03-07 |
| DE60225026D1 (de) | 2008-03-27 |
| BRPI0212299B1 (pt) | 2016-03-15 |
| MXPA04002220A (es) | 2004-06-07 |
| RU2302233C2 (ru) | 2007-07-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Free format text: PARA:INT.CI.A61K 9/48, A61K 47/10, A61K 47/14, A61K 47/02, A61P 21/00 Ipc: A61K 9/48 (2011.01), A61K 47/10 (2011.01), A61K 47 |
|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 15/03/2016, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 18A ANUIDADE. |
|
| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2595 DE 29-09-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |