AR036433A1 - Formulaciones tixotropicas oleosas - Google Patents

Formulaciones tixotropicas oleosas

Info

Publication number
AR036433A1
AR036433A1 ARP020103363A ARP020103363A AR036433A1 AR 036433 A1 AR036433 A1 AR 036433A1 AR P020103363 A ARP020103363 A AR P020103363A AR P020103363 A ARP020103363 A AR P020103363A AR 036433 A1 AR036433 A1 AR 036433A1
Authority
AR
Argentina
Prior art keywords
oleous
tixotropic
formulations
mentioned above
hydrophilic polymer
Prior art date
Application number
ARP020103363A
Other languages
English (en)
Inventor
Martin Kuentz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of AR036433A1 publication Critical patent/AR036433A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/485Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Cosmetics (AREA)

Abstract

Vehículo oleoso tixotrópico que comprende entre 0,2% y 5% (p/p) de una sílice coloidal y entre 0,2% y 5% (p/p) de un polímero hidrófilo en un aceite comestible. La interacción entre el polímero hidrófilo y el dióxido de silicio coloidal en los rangos de concentración anteriormente mencionados, permite mantener la cantidad del último componente a una baja concentración, no obstante confiriendo a la solución suficiente tixotropía y una baja viscosidad bajo corte. Cápsulas rellenas con la masa de relleno anteriormente mencionada.
ARP020103363A 2001-09-10 2002-09-06 Formulaciones tixotropicas oleosas AR036433A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01121545 2001-09-10

Publications (1)

Publication Number Publication Date
AR036433A1 true AR036433A1 (es) 2004-09-08

Family

ID=8178591

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP020103363A AR036433A1 (es) 2001-09-10 2002-09-06 Formulaciones tixotropicas oleosas

Country Status (18)

Country Link
US (3) US20030054043A1 (es)
EP (1) EP1427397B1 (es)
JP (1) JP4105091B2 (es)
KR (1) KR100598871B1 (es)
CN (1) CN1275592C (es)
AR (1) AR036433A1 (es)
AT (1) ATE385785T1 (es)
AU (1) AU2002340847B2 (es)
BR (1) BRPI0212299B1 (es)
CA (1) CA2457250C (es)
DE (1) DE60225026T2 (es)
DK (1) DK1427397T3 (es)
ES (1) ES2299604T3 (es)
MX (1) MXPA04002220A (es)
PL (1) PL202691B1 (es)
PT (1) PT1427397E (es)
RU (1) RU2302233C2 (es)
WO (1) WO2003022254A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008015186A1 (en) * 2006-08-03 2008-02-07 Unilever Plc Oral care composition
DE102007055341A1 (de) 2007-11-19 2009-05-20 Bayer Animal Health Gmbh Stabilisierung öliger Suspensionen enthaltend hydrophobe Kieselsäuren
WO2015115072A1 (ja) * 2014-01-31 2015-08-06 富士カプセル株式会社 カプセル製剤
JP6874276B2 (ja) * 2016-04-19 2021-05-19 昭和電工マテリアルズ株式会社 分離材及びカラム
DE102018122533A1 (de) * 2018-09-14 2020-03-19 Institut Dr. Rilling Healthcare Gmbh Brenn- und essbare Zusammensetzung aus mittelkettigen Trigliceriden und Kieselsäure

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1572226A (en) * 1977-11-03 1980-07-30 Hoechst Uk Ltd Pharmaceutical preparations in solid unit dosage form
GB1590864A (en) * 1978-05-16 1981-06-10 Lilly Industries Ltd Thixotropic filling medium for hard gelatin capsules
US4291015A (en) * 1979-08-14 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing a vasodilator
DE3124983A1 (de) * 1981-06-25 1983-01-20 Meditest Inst Fuer Medizinisch Arzneiformen zur oralen verabreichung
YU44680B (en) * 1982-07-30 1990-12-31 Glaxo Lab Ltd Process for obtaining very pure amorphous form of cephuroxim axetile
DE3333639A1 (de) * 1983-09-17 1985-03-28 Dynamit Nobel Ag Zubereitung von nitroestern fuer die koronartherapie
US5288500A (en) * 1987-03-13 1994-02-22 Benzon Pharma A/S Oral composition containing particles comprising an active substance
JPH03176419A (ja) * 1989-12-05 1991-07-31 Asahi Chem Ind Co Ltd チキソトロピー性付与坐剤
US5665384A (en) * 1990-04-06 1997-09-09 Rhone-Poulenc Rorer S.A. Oily capsules of ketoprofen
FR2660555B1 (fr) * 1990-04-06 1994-09-16 Rhone Poulenc Sante Gelule huileuse de ketoprofene.
US5192572A (en) * 1991-03-25 1993-03-09 The Procter & Gamble Company Method of using silica to decrease fat absorption
US5362504A (en) * 1992-06-23 1994-11-08 General Mills, Inc. Edible microwave susceptor composition
US5989586A (en) * 1992-10-05 1999-11-23 Cygnus, Inc. Two-phase matrix for sustained release drug delivery device
GB9405304D0 (en) * 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
FR2781373B1 (fr) * 1998-07-07 2001-09-21 Pf Medicament Formulations thixotropes pour le remplissage de gelules
AU1574900A (en) * 1998-12-04 2000-06-26 Provalis (Uk) Limited Pharmaceutical compositions containing insulin
EP1035115B1 (en) * 1999-02-24 2004-09-29 F. Hoffmann-La Roche Ag 4-Phenylpyridine derivatives and their use as NK-1 receptor antagonists
FR2790200B3 (fr) * 1999-02-26 2001-06-01 Sanofi Sa Formulation stable contenant de la fumagilline
DE60034770T2 (de) * 1999-02-26 2008-04-30 Sanofi-Aventis Stabile fumagillin-formulierung

Also Published As

Publication number Publication date
JP4105091B2 (ja) 2008-06-18
ATE385785T1 (de) 2008-03-15
WO2003022254A1 (en) 2003-03-20
BRPI0212299B1 (pt) 2016-03-15
PL202691B1 (pl) 2009-07-31
KR20040039341A (ko) 2004-05-10
CN1551759A (zh) 2004-12-01
JP2005501914A (ja) 2005-01-20
MXPA04002220A (es) 2004-06-07
RU2302233C2 (ru) 2007-07-10
PT1427397E (pt) 2008-03-24
BR0212299A (pt) 2004-09-14
US20090155356A1 (en) 2009-06-18
CA2457250A1 (en) 2003-03-20
KR100598871B1 (ko) 2006-07-12
ES2299604T3 (es) 2008-06-01
US20120141582A1 (en) 2012-06-07
EP1427397A1 (en) 2004-06-16
DK1427397T3 (da) 2008-05-26
CN1275592C (zh) 2006-09-20
US20030054043A1 (en) 2003-03-20
DE60225026D1 (de) 2008-03-27
AU2002340847B2 (en) 2007-09-13
PL367709A1 (en) 2005-03-07
DE60225026T2 (de) 2009-02-05
RU2004111009A (ru) 2005-08-10
EP1427397B1 (en) 2008-02-13
CA2457250C (en) 2010-03-30

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