BR0316048A - Copolìmero com estrutura controlada e utilização de um copolìmero - Google Patents

Copolìmero com estrutura controlada e utilização de um copolìmero

Info

Publication number
BR0316048A
BR0316048A BR0316048-3A BR0316048A BR0316048A BR 0316048 A BR0316048 A BR 0316048A BR 0316048 A BR0316048 A BR 0316048A BR 0316048 A BR0316048 A BR 0316048A
Authority
BR
Brazil
Prior art keywords
copolymer
units
copolier
zwiterionic
amphoteric
Prior art date
Application number
BR0316048-3A
Other languages
English (en)
Other versions
BR0316048B1 (pt
Inventor
Mathias Destarac
Original Assignee
Rhodia Chimie Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0213950A external-priority patent/FR2846973B1/fr
Priority claimed from FR0310292A external-priority patent/FR2859209B1/fr
Application filed by Rhodia Chimie Sa filed Critical Rhodia Chimie Sa
Publication of BR0316048A publication Critical patent/BR0316048A/pt
Publication of BR0316048B1 publication Critical patent/BR0316048B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8158Homopolymers or copolymers of amides or imides, e.g. (meth) acrylamide; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/90Block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/91Graft copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F293/00Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
    • C08F293/005Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule using free radical "living" or "controlled" polymerisation, e.g. using a complexing agent
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/37Polymers
    • C11D3/3796Amphoteric polymers or zwitterionic polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/54Polymers characterized by specific structures/properties

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Wood Science & Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Graft Or Block Polymers (AREA)
  • Cosmetics (AREA)
  • Detergent Compositions (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

Abstract

"COPOLìMERO COM ESTRUTURA CONTROLADA E UTILIZAçãO DE UM COPOLìMERO". A presente invenção tem por objetivo um copolímero com estrutura controlada que compreende pelo menos duas partes distintas, uma primeira parte A, anfótera ou zwiteriónica, que compreende unidades aniónicas ou potencialmente aniónicas e unidades catiónicas ou potencialmente catiónicas ou unidades zwiteriónicas e uma outra parte B, não anfótera ou zwiteriónica. Ele apresenta também grandes potenciais de adaptação, por variação de sua composição, a fim de melhorar ou de modificar as propriedades de composições nas quais ele é introduzido.
BRPI0316048-3A 2002-11-07 2003-10-31 Copolímero com estrutura controlada e utilização de um copolímero BR0316048B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
FR02/13950 2002-11-07
FR0213950A FR2846973B1 (fr) 2002-11-07 2002-11-07 Composition d'antifroissage comprenant un copolymere a architecture controlee, pour articles en fibres textiles
FR0310292A FR2859209B1 (fr) 2003-08-29 2003-08-29 Copolymere a structure controlee presentant une partie amphotere ou zwitterionique
FR03/10292 2003-08-29
PCT/FR2003/003255 WO2004044023A1 (fr) 2002-11-07 2003-10-31 Copolymere a structure controlee presentant une partie amphotere ou zwitterionique.

Publications (2)

Publication Number Publication Date
BR0316048A true BR0316048A (pt) 2005-09-13
BR0316048B1 BR0316048B1 (pt) 2014-01-28

Family

ID=32313953

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0316048-3A BR0316048B1 (pt) 2002-11-07 2003-10-31 Copolímero com estrutura controlada e utilização de um copolímero

Country Status (6)

Country Link
US (1) US7737237B2 (pt)
EP (1) EP1558658B1 (pt)
JP (1) JP2006505686A (pt)
AU (1) AU2003292304A1 (pt)
BR (1) BR0316048B1 (pt)
WO (1) WO2004044023A1 (pt)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1711541B2 (de) * 2004-01-28 2015-09-23 Basf Se Verfahren zur herstellung von polymeren
US20060018863A1 (en) * 2004-07-13 2006-01-26 Nathalie Mougin Novel ethylenic copolymers, compositions and methods of the same
WO2006125892A1 (fr) * 2005-05-23 2006-11-30 Rhodia Recherches Et Technologies Copolymere a architecture controlee issu de monomeres vinyl phosphonate, son procede de preparation et ses utilisations
FR2894585B1 (fr) * 2005-12-14 2012-04-27 Rhodia Recherches Et Tech Copolymere comprenant des unites zwitterioniques et d'autres unites, composition comprenant le copolymere, et utilisation
JP5528710B2 (ja) 2006-02-28 2014-06-25 オリガシス コーポレイション アクリロイルオキシエチルホスホリルコリン含有ポリマー抱合体及びその製法
DE102006035726A1 (de) * 2006-07-28 2008-01-31 Evonik Röhm Gmbh Verfahren zur Herstellung von ABA-Triblockcopolymeren auf (Meth)acrylatbasis
DE102006046073A1 (de) * 2006-09-27 2008-04-03 Henkel Kgaa Hyperverzweigte Polymere zur hygienischen Ausrüstung
US8394483B2 (en) * 2007-01-24 2013-03-12 Micron Technology, Inc. Two-dimensional arrays of holes with sub-lithographic diameters formed by block copolymer self-assembly
FR2923487B1 (fr) * 2007-11-09 2009-12-04 Rhodia Operations Copolymere ampholyte a architecture controlee
BRPI0806825A2 (pt) * 2007-02-06 2011-09-13 Ciba Holding Inc copolimeros em bloco polissiloxano
US8083953B2 (en) * 2007-03-06 2011-12-27 Micron Technology, Inc. Registered structure formation via the application of directed thermal energy to diblock copolymer films
US8557128B2 (en) * 2007-03-22 2013-10-15 Micron Technology, Inc. Sub-10 nm line features via rapid graphoepitaxial self-assembly of amphiphilic monolayers
US8294139B2 (en) 2007-06-21 2012-10-23 Micron Technology, Inc. Multilayer antireflection coatings, structures and devices including the same and methods of making the same
US7959975B2 (en) 2007-04-18 2011-06-14 Micron Technology, Inc. Methods of patterning a substrate
US8097175B2 (en) 2008-10-28 2012-01-17 Micron Technology, Inc. Method for selectively permeating a self-assembled block copolymer, method for forming metal oxide structures, method for forming a metal oxide pattern, and method for patterning a semiconductor structure
US8372295B2 (en) * 2007-04-20 2013-02-12 Micron Technology, Inc. Extensions of self-assembled structures to increased dimensions via a “bootstrap” self-templating method
US8404124B2 (en) * 2007-06-12 2013-03-26 Micron Technology, Inc. Alternating self-assembling morphologies of diblock copolymers controlled by variations in surfaces
FR2917415B1 (fr) * 2007-06-14 2012-10-12 Rhodia Recherches Et Tech Microgel polymerique comprenant des unites cationiques
US8080615B2 (en) 2007-06-19 2011-12-20 Micron Technology, Inc. Crosslinkable graft polymer non-preferentially wetted by polystyrene and polyethylene oxide
US8283258B2 (en) * 2007-08-16 2012-10-09 Micron Technology, Inc. Selective wet etching of hafnium aluminum oxide films
US9533006B2 (en) 2007-11-19 2017-01-03 University Of Washington Marine coatings
US8999492B2 (en) 2008-02-05 2015-04-07 Micron Technology, Inc. Method to produce nanometer-sized features with directed assembly of block copolymers
US8101261B2 (en) 2008-02-13 2012-01-24 Micron Technology, Inc. One-dimensional arrays of block copolymer cylinders and applications thereof
US8426313B2 (en) 2008-03-21 2013-04-23 Micron Technology, Inc. Thermal anneal of block copolymer films with top interface constrained to wet both blocks with equal preference
US8425982B2 (en) 2008-03-21 2013-04-23 Micron Technology, Inc. Methods of improving long range order in self-assembly of block copolymer films with ionic liquids
US8114300B2 (en) 2008-04-21 2012-02-14 Micron Technology, Inc. Multi-layer method for formation of registered arrays of cylindrical pores in polymer films
US8114301B2 (en) 2008-05-02 2012-02-14 Micron Technology, Inc. Graphoepitaxial self-assembly of arrays of downward facing half-cylinders
EP2285853B1 (en) 2008-05-13 2013-02-27 University of Washington Micellic assemblies
KR101661636B1 (ko) * 2008-05-13 2016-09-30 유니버시티 오브 워싱톤 세포로의 전달을 위한 이블록 공중합체 및 그의 폴리뉴클레오티드 복합체
CA2734917A1 (en) 2008-08-22 2010-02-25 University Of Washington Heterogeneous polymeric micelles for intracellular delivery
MX2011004242A (es) 2008-11-06 2011-07-20 Univ Washington Copolimeros multibloque.
WO2010065960A2 (en) * 2008-12-05 2010-06-10 Semprus Biosciences Corp. Non-fouling, anti-microbial, anti-thrombogenic graft-from compositions
WO2010065958A1 (en) 2008-12-05 2010-06-10 Semprus Biosciences Corp. Layered non-fouling, antimicrobial, antithrombogenic coatings
CA2751361C (en) * 2009-02-04 2016-07-19 Rhodia Operations Method for modifying the properties of an aqueous suspension
CN102905730A (zh) 2009-11-06 2013-01-30 华盛顿大学商业中心 两性离子聚合物生物缀合物以及相关的方法
US8765432B2 (en) 2009-12-18 2014-07-01 Oligasis, Llc Targeted drug phosphorylcholine polymer conjugates
SG186180A1 (en) 2010-06-09 2013-01-30 Semprus Biosciences Corp Non-fouling, anti-microbial, anti-thrombogenic graft-from compositions
EP2579906A4 (en) 2010-06-09 2016-03-23 Arrow Int Inc ARTICLES HAVING NON-CLASSING SURFACES AND METHODS FOR PREPARING THEM WITHOUT ALTERING GENERAL PHYSICAL PROPERTIES
CA2799786A1 (en) 2010-06-09 2011-12-15 Semprus Biosciences Corp. Non-fouling, anti-microbial, anti-thrombogenic graft compositions
US8304493B2 (en) 2010-08-20 2012-11-06 Micron Technology, Inc. Methods of forming block copolymers
AU2012300987A1 (en) 2011-08-31 2014-03-06 Akzo Nobel Chemicals International B.V. Laundry detergent compositions comprising soil release agent
US8900963B2 (en) 2011-11-02 2014-12-02 Micron Technology, Inc. Methods of forming semiconductor device structures, and related structures
CA2859047C (en) 2011-12-14 2017-03-21 Semprus Biosciences Corp. Redox processes for contact lens modification
EP2791223A4 (en) 2011-12-14 2015-11-18 Semprus Biosciences Corp SURFACE MODIFIED CONTACT LENSES
EP2791213A4 (en) 2011-12-14 2015-10-28 Semprus Biosciences Corp SILICONE HYDROGEN CONTACT LENS MODIFIED WITH LANTHANIDE OR TRANSITION METAL OXIDANTS
AU2012368232B2 (en) 2011-12-14 2016-01-07 Arrow International, Inc. Imbibing process for contact lens surface modification
AU2012351991B2 (en) 2011-12-14 2015-09-24 Semprus Biosciences Corp. Multistep UV process to create surface modified contact lenses
US9422387B2 (en) 2012-03-30 2016-08-23 Kimberly-Clark Worldwide, Inc. Dual responsive block copolymer compositions
US9087699B2 (en) 2012-10-05 2015-07-21 Micron Technology, Inc. Methods of forming an array of openings in a substrate, and related methods of forming a semiconductor device structure
JP6071491B2 (ja) 2012-12-03 2017-02-01 花王株式会社 毛髪化粧料
US9229328B2 (en) 2013-05-02 2016-01-05 Micron Technology, Inc. Methods of forming semiconductor device structures, and related semiconductor device structures
CA2919828C (en) 2013-07-30 2022-07-19 Phaserx, Inc. Block copolymers and their conjugates or complexes with oligonucleotides
EP3760639A1 (en) 2013-09-08 2021-01-06 Kodiak Sciences Inc. Zwitterionic polymer conjugates
US9177795B2 (en) 2013-09-27 2015-11-03 Micron Technology, Inc. Methods of forming nanostructures including metal oxides
US9481765B2 (en) 2013-12-30 2016-11-01 King Fahd University Of Petroleum And Minerals Synthesis of a diallylammonium/SO2 copolymer bearing phospho- and sulfopropyl pendents
ES2822025T3 (es) 2014-05-02 2021-04-28 Hercules Llc Composición de higiene personal para un sustrato de queratina que comprende tetrapolímero catiónico de acondicionamiento y/o estilizado
US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
KR20210013299A (ko) 2014-10-17 2021-02-03 코디악 사이언시스 인코포레이티드 부티릴콜린에스테라제 양성이온성 중합체 컨쥬게이트
CN114642735A (zh) 2015-01-21 2022-06-21 菲泽尔克斯公司 用于将治疗剂和诊断剂递送到细胞中的方法、组合物和系统
EP3095502B1 (en) * 2015-03-20 2021-01-20 Chung Yuan Christian University Double-ion charge deviation-type material for blood cell screening and method for removing leukocytes from blood sample
RU2744860C2 (ru) 2015-12-30 2021-03-16 Кодиак Сайенсиз Инк. Антитела и их конъюгаты
JP6801211B2 (ja) * 2016-03-30 2020-12-16 Dic株式会社 ブロックポリマー、並びにこれを含むコーティング剤および塗膜
EP3562510A4 (en) 2016-12-30 2021-01-06 Genevant Sciences GmbH BRANCHED PEG MOLECULES AND ASSOCIATED COMPOSITIONS AND PROCEDURES
US11752212B2 (en) * 2017-06-29 2023-09-12 University Of Washington N-oxide and ectoine monomers, polymers, their compositions, and related methods
WO2019236544A1 (en) * 2018-06-04 2019-12-12 Rhodia Operations Methods for reducing or preventing colloids adhesion and/or fouling on a substrate, compositions, and copolymers useful therefor
CN113939358A (zh) * 2019-05-10 2022-01-14 塔夫茨大学信托人 两性离子带电共聚物膜
CA3157509A1 (en) 2019-10-10 2021-04-15 Kodiak Sciences Inc. Methods of treating an eye disorder
CN113999343A (zh) * 2021-11-08 2022-02-01 新凤鸣集团股份有限公司 一种两性离子型有机硅季铵盐聚合物及其制备方法和应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4395444A (en) * 1981-09-25 1983-07-26 Ppg Industries, Inc. Thermosetting cationic acrylic latex compositions containing blocked isocyanates
US5219945A (en) * 1992-02-20 1993-06-15 E. I. Du Pont De Nemours And Company ABC triblock methacrylate polymers
JPH09279084A (ja) * 1996-04-16 1997-10-28 Showa Highpolymer Co Ltd 含浸加工紙用乳化重合組成物
US6074628A (en) * 1997-04-25 2000-06-13 Procter & Gamble Hairspray compositions containing silicon block copolymers
US6812291B1 (en) * 1997-12-31 2004-11-02 Rhodia Chimie Method for block polymer synthesis by controlled radical polymerization from dithiocarbamate compounds
JP2963897B1 (ja) * 1998-07-15 1999-10-18 大成化工株式会社 分散機能を有する両性樹脂の製造方法
FR2794464B1 (fr) * 1999-06-04 2005-03-04 Rhodia Chimie Sa Procede de synthese de polymeres a blocs par polymerisation radicalaire controlee a l'aide de thioether-thiones
FR2813313B1 (fr) * 2000-08-25 2007-06-15 Rhodia Chimie Sa Composition a base de nanoparticules ou de nanolatex de polymeres pour le soin du linge
EP1325046B1 (en) * 2000-10-06 2007-06-27 Biocompatibles UK Limited Zwitterionic polymers
US6576722B2 (en) * 2000-12-13 2003-06-10 Ppg Industries Ohio, Inc. Acrylic-halogenated polyolefin copolymer adhesion promoters
US6849679B2 (en) * 2001-05-21 2005-02-01 Ciba Specialty Chemicals Corporation Pigment compositions with modified block copolymer dispersants
US7141519B2 (en) * 2002-09-20 2006-11-28 Kimberly-Clark Worldwide, Inc. Ion triggerable, cationic polymers, a method of making same and items using same

Also Published As

Publication number Publication date
EP1558658A1 (fr) 2005-08-03
WO2004044023A1 (fr) 2004-05-27
BR0316048B1 (pt) 2014-01-28
EP1558658B1 (fr) 2012-12-19
JP2006505686A (ja) 2006-02-16
AU2003292304A1 (en) 2004-06-03
US7737237B2 (en) 2010-06-15
US20060217285A1 (en) 2006-09-28

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Legal Events

Date Code Title Description
B07A Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 28/01/2014, OBSERVADAS AS CONDICOES LEGAIS.

B15K Others concerning applications: alteration of classification

Ipc: A61Q 5/00 (2006.01), A61K 8/81 (2006.01), A61K 8/9