BR0202685A - Compostos benzenossulfonamida, processo para sua preparação e composiçoes farmacêuticas contendo os mesmos - Google Patents

Compostos benzenossulfonamida, processo para sua preparação e composiçoes farmacêuticas contendo os mesmos

Info

Publication number
BR0202685A
BR0202685A BR0202685-6A BR0202685A BR0202685A BR 0202685 A BR0202685 A BR 0202685A BR 0202685 A BR0202685 A BR 0202685A BR 0202685 A BR0202685 A BR 0202685A
Authority
BR
Brazil
Prior art keywords
group
sym
preparation
inclusive
pharmaceutical compositions
Prior art date
Application number
BR0202685-6A
Other languages
English (en)
Inventor
Gilbert Lavielle
Thierry Dubuffet
Bernard Cimetiere
Tony Verbeuren
Serge Simonet
Christine Vayssetts-Courchay
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of BR0202685A publication Critical patent/BR0202685A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

"COMPOSTOS BENZENOSSULFONAMIDA, PROCESSO PARA SUA PREPARAçãO E COMPOSIçõES FARMACêUTICAS CONTENDO OS MESMOS". Composto da fórmula (I): onde: G representa um grupo, tal como: <sym> onde R^ 1^ e R^ 2^ independentemente representam um átomo de hidrogênio, ou um grupo alquila, cicloalquila, arila, arialquila, cicloalquila, cicloalquilalquila, heteroarila ou heteroarilalquila ou R^ 1^ e R^ 2^ em conjunto com o átomo de nitrogênio formam um grupo heterocicloalquila <sym> R^ 3^ representa um átomo de hidrogênio ou um grupo alquila ou fenila opcionalmente substituído,<sym> R~ a~ representa um grupo hidróxi, um grupo (C~ 1~-C~ 6~) alcóxi linear ou ramificado ou um grupo amino, <sym> R~ b~ e R~ c~, que podem ser idênticos ou diferentes, cada um representa um átomo de hidrogênio, um átomo de halogênio, um grupo alquila, um grupo alcóxi, um grupo hidróxi ou um grupo trihaloalquila, <sym> m é um número inteiro de 0 a 1 inclusive, <sym> n e q são números inteiros idênticos ou diferentes de 0 a 6 inclusive, <sym> p e r são números inteiros idênticos ou diferentes de 1 a 6 inclusive medicamentos.
BR0202685-6A 2001-07-13 2002-07-12 Compostos benzenossulfonamida, processo para sua preparação e composiçoes farmacêuticas contendo os mesmos BR0202685A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0109339A FR2827280B1 (fr) 2001-07-13 2001-07-13 Nouveaux derives de benzene sulfonamide, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
BR0202685A true BR0202685A (pt) 2003-05-06

Family

ID=8865462

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0202685-6A BR0202685A (pt) 2001-07-13 2002-07-12 Compostos benzenossulfonamida, processo para sua preparação e composiçoes farmacêuticas contendo os mesmos

Country Status (24)

Country Link
US (1) US6541471B1 (pt)
EP (1) EP1275641B1 (pt)
JP (1) JP3770858B2 (pt)
KR (1) KR100503157B1 (pt)
CN (1) CN1186318C (pt)
AR (1) AR035257A1 (pt)
AT (1) ATE286877T1 (pt)
AU (1) AU2002300092B2 (pt)
BR (1) BR0202685A (pt)
CA (1) CA2393995C (pt)
DE (1) DE60202554T2 (pt)
DK (1) DK1275641T3 (pt)
EA (1) EA005376B1 (pt)
ES (1) ES2234994T3 (pt)
FR (1) FR2827280B1 (pt)
HK (1) HK1050675A1 (pt)
HU (1) HUP0202284A3 (pt)
MX (1) MXPA02006853A (pt)
NO (1) NO20023390L (pt)
NZ (1) NZ520141A (pt)
PL (1) PL355009A1 (pt)
PT (1) PT1275641E (pt)
SI (1) SI1275641T1 (pt)
ZA (1) ZA200205597B (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106083546A (zh) * 2016-06-20 2016-11-09 上海引盛生物科技有限公司 一种3,5‑二溴苯甲醛的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02304022A (ja) * 1989-05-18 1990-12-17 Mitsubishi Kasei Corp セロトニン拮抗剤
US5364866A (en) * 1989-05-19 1994-11-15 Hoechst-Roussel Pharmaceuticals, Inc. Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics
ATE167473T1 (de) * 1990-08-20 1998-07-15 Eisai Co Ltd Sulfonamid-derivate
TW219358B (pt) * 1991-12-20 1994-01-21 Hokuriku Pharmaceutical
GB9220137D0 (en) * 1992-09-23 1992-11-04 Pfizer Ltd Therapeutic agents
JPH0753505A (ja) * 1992-10-01 1995-02-28 Hokuriku Seiyaku Co Ltd ベンゼンスルホンアミド誘導体及びその用途
FR2760235B1 (fr) * 1997-02-28 1999-04-09 Adir Nouveaux derives de benzenesulfonylamine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
SI1275641T1 (en) 2005-04-30
MXPA02006853A (es) 2005-07-25
CN1397547A (zh) 2003-02-19
NO20023390L (no) 2003-01-14
DK1275641T3 (da) 2005-04-25
EP1275641A3 (fr) 2003-05-14
DE60202554T2 (de) 2005-12-29
PT1275641E (pt) 2005-05-31
CA2393995C (fr) 2008-06-10
KR100503157B1 (ko) 2005-07-25
ZA200205597B (en) 2003-03-27
DE60202554D1 (de) 2005-02-17
HUP0202284A3 (en) 2005-02-28
JP3770858B2 (ja) 2006-04-26
ATE286877T1 (de) 2005-01-15
AR035257A1 (es) 2004-05-05
CN1186318C (zh) 2005-01-26
PL355009A1 (en) 2003-01-27
FR2827280A1 (fr) 2003-01-17
HU0202284D0 (pt) 2002-09-28
AU2002300092B2 (en) 2007-07-12
NO20023390D0 (no) 2002-07-12
HK1050675A1 (en) 2003-07-04
FR2827280B1 (fr) 2003-10-31
EA005376B1 (ru) 2005-02-24
US6541471B1 (en) 2003-04-01
JP2003113156A (ja) 2003-04-18
EA200200666A1 (ru) 2003-02-27
HUP0202284A2 (hu) 2003-02-28
CA2393995A1 (fr) 2003-01-13
ES2234994T3 (es) 2005-07-01
EP1275641B1 (fr) 2005-01-12
EP1275641A2 (fr) 2003-01-15
NZ520141A (en) 2003-11-28
KR20030007174A (ko) 2003-01-23

Similar Documents

Publication Publication Date Title
BR0111230A (pt) Composto, e, uso e processo para a preparação do mesmo
DK0641333T3 (da) Fremgangsmåde til fremstilling af mellemprodukter, som er anvendelige ved syntese af retrovirus- protease-inhibitorer
BR9907429A (pt) Composto de hidrazida, processo para sua preparação e composições farmacêuticas contendo os mesmos
ES2104754T3 (es) Derivados de urea ciclicos, medicamentos que contienen estos compuestos y procedimiento para su preparacion.
BR0211427A (pt) Compostos, processo para preparar os mesmos, composição adequada para combater fungos danosos, uso de compostos, e, processo para combater fungos danosos
MXPA04001016A (es) Derivados de sulfonamida como inhibidores de la gamma secretasa.
BR0200982A (pt) Compostos do ácido alfa-amino sulfonila, um processo para sua preparação e composições farmacêuticas compreendendo os mesmos
BR9910326A (pt) Processo para preeparar isoxazóis, composto, processo para preparar compostos, uso de compostos, e, processo para preparar tioéteres
HUP0402235A2 (hu) 4,4-Difluor-1,2,3,4-tetrahidro-5H-1-benzazepin-származékok és ezek sói és ezeket tartalmazó gyógyszerkészítmények
BR9805031A (pt) Compostos de naftaleno, processo para sua preparação e composições farmacêuticas contendo os mesmos.
BR0003313A (pt) Novos compostos diméricos substituìdos, um processo para a preparação dos mesmos e composições farmacêuticas que contêm os mesmos
HUP0201357A2 (hu) Aszimmetrikus rézkomplex, előállítása, és eljárás ciklopropánkarbonsav-észter-származékok előállítására felhasználásával
EA200100090A3 (ru) Новые пиперидин-4-сульфонамидные производные, способ их получения и содержащие их фармацевтические композиции
HUP0201475A2 (hu) Heteroarilamidin-, metilamidin- és guanidinszármazékok, előállításuk és alkalmazásuk, valamint e vegyületeket tartalmazó gyógyászati készítmények
BR0100107A (pt) Compostos de benzenossulfonamida, um processo para sua preparação e composições farmacêuticas que contêm os mesmos
BR0202685A (pt) Compostos benzenossulfonamida, processo para sua preparação e composiçoes farmacêuticas contendo os mesmos
HUP0402341A2 (hu) Szubsztituált tiazol-2-ilaminokat tartalmazó készítmények rák kezelésére
HUP0303945A2 (hu) Nukleofil szubsztitúcióban alkalmazható katalizátorok, eljárás előállításukra, az ezeket tartalmazó készítmények és alkalmazásuk
BR0002287A (pt) Compostos de piridina ou piperidina substituìdas, processo para preparação deles e composições farmacêuticas contendo-os
DE60222244D1 (de) Verfahren zur herstellung von zwischenverbindungen in der herstellung von discodermolid und discodermolid-analoga
BR9803702A (pt) Processo para preparação de produtos de politriazina contendo grupos 2,2,6,6-tetrametil-4-piperidila.
EA200200665A1 (ru) Новые соединения бензолсульфонамида, способ их получения и фармацевтические композиции, их содержащие
BR0211180A (pt) Compostos, processo para preparar os mesmos, intermediários, e, composição adequada e método para controlar fungos fitopatogênicos
EA200300458A1 (ru) Новые соединения аминотриазолона, способ их получения и фармацевтические композиции, содержащие их
DK1432677T3 (da) Urinstofoligomerer, fremgangsmåde til fremstilling heraf og sammensætninger indeholdende disse

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE 8A. ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2103 DE 26/04/2011.