BR0201515A - Sistema e método para manipular partìculas magneticamente respondentes em amostras de fluido para coleta de dna ou rna de uma amostra - Google Patents
Sistema e método para manipular partìculas magneticamente respondentes em amostras de fluido para coleta de dna ou rna de uma amostraInfo
- Publication number
- BR0201515A BR0201515A BR0201515-3A BR0201515A BR0201515A BR 0201515 A BR0201515 A BR 0201515A BR 0201515 A BR0201515 A BR 0201515A BR 0201515 A BR0201515 A BR 0201515A
- Authority
- BR
- Brazil
- Prior art keywords
- particles
- solution
- dna
- nucleic acid
- acid molecules
- Prior art date
Links
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/28—Magnetic plugs and dipsticks
- B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
- C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
- C12N15/1013—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/26—Details of magnetic or electrostatic separation for use in medical applications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/103—General features of the devices using disposable tips
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/028—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having reaction cells in the form of microtitration plates
Abstract
"SISTEMA E MéTODO PARA MANIPULAR PARTìCULAS MAGNETICAMENTE RESPONDENTES EM AMOSTRAS DE FLUIDO PARA COLETA DE DNA OU RNA DE UMA AMOSTRA". Trata-se de um sistema e um método para manipular as partículas magneticamente respondentes em uma solução com o fim de separar moléculas de ácido nucléico de componentes de célula em uma solução celular. O sistema e o método empregam um dispositivo capaz de alojar uma série de tubos, cada um dos quais contém respectivas partículas de amostragem e as partículas magneticamente respondentes. O dispositivo inclui dispositivos de aquecimento e resfriamento para facilitar a etapa de lisagem com a finalidade de desprender as moléculas de ácido nucléico das células na solução celular. O dispositivo inclui ainda ímãs móveis que podem ser movidos até as ou em afastamento das proximidades do tubo de modo a reter as partículas magneticamente respondentes às quais as moléculas de ácido nucléico se tornam ligadas, de modo que as partículas ligadas a moléculas possam ser separadas do restante da solução, e lavadas conforme apropriado. O sistema emprega também um eletroímã capaz de desmagnetizar as partículas, de modo que as partículas possam misturar-se com a solução, como, por exemplo, soluções de elução que são usadas para desligar as moléculas das partículas.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/858,889 US6672458B2 (en) | 2000-05-19 | 2001-05-17 | System and method for manipulating magnetically responsive particles fluid samples to collect DNA or RNA from a sample |
Publications (2)
Publication Number | Publication Date |
---|---|
BR0201515A true BR0201515A (pt) | 2003-02-11 |
BR0201515B1 BR0201515B1 (pt) | 2013-08-06 |
Family
ID=25329438
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0201515-3B1A BR0201515B1 (pt) | 2001-05-17 | 2002-04-30 | "sistema e mÉtodo para manipular partÍculas magneticamente responsivas em amostras de fluido para coleta de dna ou rna de uma amostra" |
Country Status (8)
Country | Link |
---|---|
US (2) | US6672458B2 (pt) |
EP (1) | EP1260583A1 (pt) |
JP (1) | JP3676754B2 (pt) |
AU (1) | AU785010B2 (pt) |
BR (1) | BR0201515B1 (pt) |
CA (1) | CA2380919C (pt) |
FI (1) | FI119552B (pt) |
NO (1) | NO330113B1 (pt) |
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-
2001
- 2001-05-17 US US09/858,889 patent/US6672458B2/en not_active Expired - Lifetime
-
2002
- 2002-03-28 EP EP02007127A patent/EP1260583A1/en not_active Withdrawn
- 2002-04-05 CA CA2380919A patent/CA2380919C/en not_active Expired - Lifetime
- 2002-04-30 BR BRPI0201515-3B1A patent/BR0201515B1/pt not_active IP Right Cessation
- 2002-05-02 JP JP2002130533A patent/JP3676754B2/ja not_active Expired - Lifetime
- 2002-05-10 AU AU40591/02A patent/AU785010B2/en not_active Expired
- 2002-05-16 NO NO20022351A patent/NO330113B1/no not_active IP Right Cessation
- 2002-05-16 FI FI20020923A patent/FI119552B/fi not_active IP Right Cessation
- 2002-10-11 US US10/269,903 patent/US20030038071A1/en not_active Abandoned
Also Published As
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NO20022351L (no) | 2002-11-18 |
JP2003093918A (ja) | 2003-04-02 |
JP3676754B2 (ja) | 2005-07-27 |
FI119552B (fi) | 2008-12-31 |
NO330113B1 (no) | 2011-02-21 |
US20020014443A1 (en) | 2002-02-07 |
EP1260583A1 (en) | 2002-11-27 |
CA2380919C (en) | 2011-09-27 |
FI20020923A0 (fi) | 2002-05-16 |
FI20020923A (fi) | 2002-11-18 |
AU4059102A (en) | 2002-11-21 |
AU785010B2 (en) | 2006-08-24 |
US20030038071A1 (en) | 2003-02-27 |
US6672458B2 (en) | 2004-01-06 |
BR0201515B1 (pt) | 2013-08-06 |
CA2380919A1 (en) | 2002-11-17 |
NO20022351D0 (no) | 2002-05-16 |
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