BR0112300A - Processo amplamente aplicável para a identificação de moduladores de receptores acoplados à proteìna g - Google Patents

Processo amplamente aplicável para a identificação de moduladores de receptores acoplados à proteìna g

Info

Publication number
BR0112300A
BR0112300A BR0112300-9A BR0112300A BR0112300A BR 0112300 A BR0112300 A BR 0112300A BR 0112300 A BR0112300 A BR 0112300A BR 0112300 A BR0112300 A BR 0112300A
Authority
BR
Brazil
Prior art keywords
protein
pathway
coupled receptor
identification
receptor modulators
Prior art date
Application number
BR0112300-9A
Other languages
English (en)
Other versions
BR0112300B1 (pt
Inventor
Evi Kostenis
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of BR0112300A publication Critical patent/BR0112300A/pt
Publication of BR0112300B1 publication Critical patent/BR0112300B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
  • Inspection Of Paper Currency And Valuable Securities (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"PROCESSO AMPLAMENTE APLICáVEL PARA A IDENTIFICAçãO DE MODULADORES DE RECEPTORES ACOPLADOS A PROTEìNA G". A invenção refere-se a um processo amplamente aplicável para a identificação de compostos químicos, os quais modulam receptores acoplados à proteína G, por meio de novas proteínas G híbridas com especificidade do receptor muito ampla e expressão muito elevada bem como compostos químicos, os quais podem ser identificados por um tal processo.
BRPI0112300-9A 2000-07-08 2001-07-05 Processo para identificação de composto químico, polinucleotídeo, célula hospederia, processo para preparar célula hospedeira e seu uso, proteína, processo para sua preparação e seu uso BR0112300B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10033353A DE10033353A1 (de) 2000-07-08 2000-07-08 Breit einsetzbares Verfahren zur Identifizierung von Modulatoren von G-Protein gekoppelten Rezeptoren
DE10033353.2 2000-07-08
PCT/EP2001/007667 WO2002004665A2 (de) 2000-07-08 2001-07-05 Breit einsetzbares verfahren zur identifizierung von modulatoren von g-protein gekoppelten rezeptoren

Publications (2)

Publication Number Publication Date
BR0112300A true BR0112300A (pt) 2004-07-27
BR0112300B1 BR0112300B1 (pt) 2014-01-21

Family

ID=7648325

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0112300-9A BR0112300B1 (pt) 2000-07-08 2001-07-05 Processo para identificação de composto químico, polinucleotídeo, célula hospederia, processo para preparar célula hospedeira e seu uso, proteína, processo para sua preparação e seu uso

Country Status (19)

Country Link
US (2) US20040002109A9 (pt)
EP (1) EP1319022B1 (pt)
JP (1) JP4991081B2 (pt)
KR (1) KR100922701B1 (pt)
AT (1) ATE462721T1 (pt)
AU (2) AU7252201A (pt)
BR (1) BR0112300B1 (pt)
CA (1) CA2415460C (pt)
CY (1) CY1110049T1 (pt)
DE (2) DE10033353A1 (pt)
DK (1) DK1319022T3 (pt)
ES (1) ES2342453T3 (pt)
IL (2) IL153818A0 (pt)
MX (1) MXPA02012641A (pt)
NO (2) NO330684B1 (pt)
NZ (1) NZ523480A (pt)
PT (1) PT1319022E (pt)
WO (1) WO2002004665A2 (pt)
ZA (1) ZA200300707B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002213409A1 (en) * 2000-10-30 2002-05-15 Senomyx, Inc. Galphaqproetin variants and their use in the analysis and discovery of agonists and antagonists of chemosensory receptors
US20050112701A1 (en) * 2003-09-11 2005-05-26 Aventis Pharma Deutschland Gmbh Test system for the identification of APJ receptor ligands
EP1520861A1 (en) * 2003-09-11 2005-04-06 Aventis Pharma Deutschland GmbH Test system for the identification of APJ receptor ligands
DE102007002260A1 (de) 2007-01-16 2008-07-31 Sanofi-Aventis Verwendung von substituierten Pyranonsäurederivaten zur Herstellung von Medikamenten zur Behandlung des Metabolischen Syndroms
EP2303270B1 (en) 2008-05-05 2017-05-17 Sanofi Acylamino-substituted fused cyclopentanecarboxylic acid derivatives and their use as pharmaceuticals
AR079022A1 (es) 2009-11-02 2011-12-21 Sanofi Aventis Derivados de acido carboxilico ciclico sustituidos con acilamino, su uso como productos farmaceuticos, composicion farmaceutica y metodo de preparacion
EP2862574A1 (en) 2013-10-15 2015-04-22 Sanofi {4-[5-(3-chloro-phenoxy)-oxazolo[5,4 d]pyrimidin-2-yl]-2,6-dimethyl-phenoxy}-acetic acid for use in the prevention or treatment of acute kidney injury
CN109946450B (zh) * 2019-04-16 2022-04-19 浙江诺迦生物科技有限公司 一种基于细胞内游离钙离子浓度变化效应的阿片类活性物质的检测方法及其检测试剂盒
CN109946451B (zh) * 2019-04-16 2022-05-20 浙江诺迦生物科技有限公司 一种基于细胞内游离钙离子浓度变化效应的大麻素类活性物质的检测方法及其检测试剂盒

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6004808A (en) * 1996-06-21 1999-12-21 Aurora Biosciences Corporation Promiscuous G-protein compositions and their use
WO1999005177A1 (en) 1997-07-28 1999-02-04 The Regents Of The University Of California Methods and compositions for identifying modulators of g-protein-coupled receptors

Also Published As

Publication number Publication date
AU7252201A (en) 2002-01-21
NO20101390L (no) 2003-01-07
BR0112300B1 (pt) 2014-01-21
ES2342453T3 (es) 2010-07-07
JP4991081B2 (ja) 2012-08-01
PT1319022E (pt) 2010-06-11
NO330684B1 (no) 2011-06-06
CY1110049T1 (el) 2015-01-14
JP2004502463A (ja) 2004-01-29
NO20030068L (no) 2003-01-07
US20040002109A9 (en) 2004-01-01
AU2001272522B2 (en) 2007-05-31
CA2415460C (en) 2011-05-10
EP1319022B1 (de) 2010-03-31
US20020127601A1 (en) 2002-09-12
KR20030021246A (ko) 2003-03-12
IL153818A (en) 2010-05-31
DK1319022T3 (da) 2010-07-26
IL153818A0 (en) 2003-07-31
EP1319022A2 (de) 2003-06-18
CA2415460A1 (en) 2002-01-17
DE50115416D1 (de) 2010-05-12
KR100922701B1 (ko) 2009-10-22
WO2002004665A3 (de) 2002-12-19
DE10033353A1 (de) 2002-01-24
US20050255531A1 (en) 2005-11-17
WO2002004665A2 (de) 2002-01-17
ATE462721T1 (de) 2010-04-15
MXPA02012641A (es) 2003-04-25
NZ523480A (en) 2008-04-30
ZA200300707B (en) 2004-04-15
NO20030068D0 (no) 2003-01-07
US7378252B2 (en) 2008-05-27

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: SANOFI-AVENTIS DEUTSCHLAND GMBH (DE)

Free format text: ALTERADO DE: AVENTIS PHARMA DEUTSCHLAND GMBH

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 21/01/2014, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 14A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2313 DE 05-05-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.