ATE121421T1 - Hemmung von migration von zellen mit hilfe von synthetischen peptiden. - Google Patents
Hemmung von migration von zellen mit hilfe von synthetischen peptiden.Info
- Publication number
- ATE121421T1 ATE121421T1 AT89103359T AT89103359T ATE121421T1 AT E121421 T1 ATE121421 T1 AT E121421T1 AT 89103359 T AT89103359 T AT 89103359T AT 89103359 T AT89103359 T AT 89103359T AT E121421 T1 ATE121421 T1 AT E121421T1
- Authority
- AT
- Austria
- Prior art keywords
- cells
- gly
- asp
- membrane
- arg
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 230000005764 inhibitory process Effects 0.000 title 1
- 230000005012 migration Effects 0.000 title 1
- 238000013508 migration Methods 0.000 title 1
- 102000012422 Collagen Type I Human genes 0.000 abstract 2
- 108010022452 Collagen Type I Proteins 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 210000004379 membrane Anatomy 0.000 abstract 2
- 239000012528 membrane Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- UMZVBZDHGKJFGQ-LLLAAFKUSA-N (2s)-1-[(2s,3r)-2-[[(2s)-2-[[2-[[(2s)-2-[(2-aminoacetyl)amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]-3-hydroxybutanoyl]pyrrolidine-2-carboxylic acid Chemical compound NC(=N)NCCC[C@H](NC(=O)CN)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@H](O)C)C(=O)N1CCC[C@H]1C(O)=O UMZVBZDHGKJFGQ-LLLAAFKUSA-N 0.000 abstract 1
- IYMAXBFPHPZYIK-BQBZGAKWSA-N Arg-Gly-Asp Chemical compound NC(N)=NCCC[C@H](N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(O)=O IYMAXBFPHPZYIK-BQBZGAKWSA-N 0.000 abstract 1
- 102100037362 Fibronectin Human genes 0.000 abstract 1
- 108010067306 Fibronectins Proteins 0.000 abstract 1
- 102100035140 Vitronectin Human genes 0.000 abstract 1
- 108010031318 Vitronectin Proteins 0.000 abstract 1
- 150000001413 amino acids Chemical group 0.000 abstract 1
- 210000001691 amnion Anatomy 0.000 abstract 1
- 108010072041 arginyl-glycyl-aspartic acid Proteins 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 108010000421 fibronectin attachment peptide Proteins 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 230000009545 invasion Effects 0.000 abstract 1
- 230000003211 malignant effect Effects 0.000 abstract 1
- 230000000149 penetrating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16653088A | 1988-03-10 | 1988-03-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE121421T1 true ATE121421T1 (de) | 1995-05-15 |
Family
ID=22603704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89103359T ATE121421T1 (de) | 1988-03-10 | 1989-02-25 | Hemmung von migration von zellen mit hilfe von synthetischen peptiden. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0332912B1 (de) |
| JP (2) | JPH024716A (de) |
| AT (1) | ATE121421T1 (de) |
| CA (1) | CA1324954C (de) |
| DE (1) | DE68922234T2 (de) |
| ES (1) | ES2073414T3 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2662830B2 (ja) * | 1990-10-26 | 1997-10-15 | 富士写真フイルム株式会社 | Ｃｍ−キチン誘導体およびその用途 |
| CA2074945A1 (en) * | 1990-11-30 | 1992-05-31 | Atsushi Isoai | Tumor cell invasion-inhibiting peptides, peptide complexes and cancer metastasis inhibitors |
| US5879657A (en) * | 1993-03-30 | 1999-03-09 | The Dupont Merck Pharmaceutical Company | Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders |
| WO2003038431A1 (en) * | 2001-10-26 | 2003-05-08 | The Regents Of The University Of California | Method for screening combinatorial bead library, capturing cells from body fluids, and ligands for cancer cells |
| EP1608681B1 (de) * | 2003-03-28 | 2008-06-04 | FUJIFILM Manufacturing Europe B.V. | Rgd-angereicherte gelatine-ähnliche proteine mit verstärkter zellbindung |
| WO2009046826A1 (en) * | 2007-09-11 | 2009-04-16 | Mondobiotech Laboratories Ag | Use of a cyclic penta-peptide as a therapeutic agent |
| WO2009033725A1 (en) * | 2007-09-11 | 2009-03-19 | Mondobiotech Laboratories Ag | Use of human neuropeptide as a therapeutic agent |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0275748B1 (de) * | 1986-12-15 | 1992-08-19 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Peptid-Derivate und deren Verwendung in der Therapie |
| IT1222437B (it) * | 1987-08-04 | 1990-09-05 | Ellem Ind Farmaceutica | Tripeptidi utili come immunostimolanti e nella prevenzione delle metastasi e relativo procedimento di preparazione |
-
1989
- 1989-02-17 CA CA000591334A patent/CA1324954C/en not_active Expired - Fee Related
- 1989-02-25 ES ES89103359T patent/ES2073414T3/es not_active Expired - Lifetime
- 1989-02-25 AT AT89103359T patent/ATE121421T1/de not_active IP Right Cessation
- 1989-02-25 DE DE68922234T patent/DE68922234T2/de not_active Expired - Lifetime
- 1989-02-25 EP EP89103359A patent/EP0332912B1/de not_active Expired - Lifetime
- 1989-03-09 JP JP1057663A patent/JPH024716A/ja active Pending
-
1996
- 1996-05-22 JP JP8126684A patent/JP2744902B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2073414T3 (es) | 1995-08-16 |
| CA1324954C (en) | 1993-12-07 |
| DE68922234D1 (de) | 1995-05-24 |
| DE68922234T2 (de) | 1995-08-31 |
| EP0332912A3 (en) | 1989-11-08 |
| JPH08332097A (ja) | 1996-12-17 |
| EP0332912B1 (de) | 1995-04-19 |
| JPH024716A (ja) | 1990-01-09 |
| EP0332912A2 (de) | 1989-09-20 |
| JP2744902B2 (ja) | 1998-04-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |