MXPA02012641A - Metodo con una amplia gama de aplicaciones, para identificar moduladores de receptores acoplados a proteina g. - Google Patents

Metodo con una amplia gama de aplicaciones, para identificar moduladores de receptores acoplados a proteina g.

Info

Publication number
MXPA02012641A
MXPA02012641A MXPA02012641A MXPA02012641A MXPA02012641A MX PA02012641 A MXPA02012641 A MX PA02012641A MX PA02012641 A MXPA02012641 A MX PA02012641A MX PA02012641 A MXPA02012641 A MX PA02012641A MX PA02012641 A MXPA02012641 A MX PA02012641A
Authority
MX
Mexico
Prior art keywords
protein
applications
wide range
coupled receptors
identifying modulators
Prior art date
Application number
MXPA02012641A
Other languages
English (en)
Inventor
Evi Kostenis
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of MXPA02012641A publication Critical patent/MXPA02012641A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
  • Inspection Of Paper Currency And Valuable Securities (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La invencion se refiere a un metodo con una amplia gama de aplicaciones, para identificar compuestos quimicos que modulan los receptores acoplados a proteina G a traves de proteinas G hibridas novedosas con una especificidad de receptor extremadamente amplia y una expresion extremadamente elevada. La invencion se refiere tambien a compuestos quimicos que pueden ser identificados por un metodo de este tipo.
MXPA02012641A 2000-07-08 2001-07-05 Metodo con una amplia gama de aplicaciones, para identificar moduladores de receptores acoplados a proteina g. MXPA02012641A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10033353A DE10033353A1 (de) 2000-07-08 2000-07-08 Breit einsetzbares Verfahren zur Identifizierung von Modulatoren von G-Protein gekoppelten Rezeptoren
PCT/EP2001/007667 WO2002004665A2 (de) 2000-07-08 2001-07-05 Breit einsetzbares verfahren zur identifizierung von modulatoren von g-protein gekoppelten rezeptoren

Publications (1)

Publication Number Publication Date
MXPA02012641A true MXPA02012641A (es) 2003-04-25

Family

ID=7648325

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02012641A MXPA02012641A (es) 2000-07-08 2001-07-05 Metodo con una amplia gama de aplicaciones, para identificar moduladores de receptores acoplados a proteina g.

Country Status (19)

Country Link
US (2) US20040002109A9 (es)
EP (1) EP1319022B1 (es)
JP (1) JP4991081B2 (es)
KR (1) KR100922701B1 (es)
AT (1) ATE462721T1 (es)
AU (2) AU2001272522B2 (es)
BR (1) BR0112300B1 (es)
CA (1) CA2415460C (es)
CY (1) CY1110049T1 (es)
DE (2) DE10033353A1 (es)
DK (1) DK1319022T3 (es)
ES (1) ES2342453T3 (es)
IL (2) IL153818A0 (es)
MX (1) MXPA02012641A (es)
NO (2) NO330684B1 (es)
NZ (1) NZ523480A (es)
PT (1) PT1319022E (es)
WO (1) WO2002004665A2 (es)
ZA (1) ZA200300707B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002213409A1 (en) * 2000-10-30 2002-05-15 Senomyx, Inc. Galphaqproetin variants and their use in the analysis and discovery of agonists and antagonists of chemosensory receptors
US20050112701A1 (en) * 2003-09-11 2005-05-26 Aventis Pharma Deutschland Gmbh Test system for the identification of APJ receptor ligands
EP1520861A1 (en) * 2003-09-11 2005-04-06 Aventis Pharma Deutschland GmbH Test system for the identification of APJ receptor ligands
DE102007002260A1 (de) 2007-01-16 2008-07-31 Sanofi-Aventis Verwendung von substituierten Pyranonsäurederivaten zur Herstellung von Medikamenten zur Behandlung des Metabolischen Syndroms
CN105418450A (zh) 2008-05-05 2016-03-23 赛诺菲-安万特 酰基氨基取代的稠合环戊烷羧酸衍生物及它们作为药物的用途
AR079022A1 (es) 2009-11-02 2011-12-21 Sanofi Aventis Derivados de acido carboxilico ciclico sustituidos con acilamino, su uso como productos farmaceuticos, composicion farmaceutica y metodo de preparacion
EP2862574A1 (en) 2013-10-15 2015-04-22 Sanofi {4-[5-(3-chloro-phenoxy)-oxazolo[5,4 d]pyrimidin-2-yl]-2,6-dimethyl-phenoxy}-acetic acid for use in the prevention or treatment of acute kidney injury
CN109946450B (zh) * 2019-04-16 2022-04-19 浙江诺迦生物科技有限公司 一种基于细胞内游离钙离子浓度变化效应的阿片类活性物质的检测方法及其检测试剂盒
CN109946451B (zh) * 2019-04-16 2022-05-20 浙江诺迦生物科技有限公司 一种基于细胞内游离钙离子浓度变化效应的大麻素类活性物质的检测方法及其检测试剂盒

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6004808A (en) * 1996-06-21 1999-12-21 Aurora Biosciences Corporation Promiscuous G-protein compositions and their use
US6383761B2 (en) * 1997-07-28 2002-05-07 The Regents Of The University Of California Methods and compositions for identifying modulators of G-protein-coupled receptors

Also Published As

Publication number Publication date
JP4991081B2 (ja) 2012-08-01
DK1319022T3 (da) 2010-07-26
US7378252B2 (en) 2008-05-27
US20050255531A1 (en) 2005-11-17
WO2002004665A2 (de) 2002-01-17
NO20030068L (no) 2003-01-07
CY1110049T1 (el) 2015-01-14
KR100922701B1 (ko) 2009-10-22
NO20101390L (no) 2003-01-07
DE10033353A1 (de) 2002-01-24
BR0112300A (pt) 2004-07-27
KR20030021246A (ko) 2003-03-12
IL153818A (en) 2010-05-31
ES2342453T3 (es) 2010-07-07
DE50115416D1 (de) 2010-05-12
US20020127601A1 (en) 2002-09-12
BR0112300B1 (pt) 2014-01-21
US20040002109A9 (en) 2004-01-01
PT1319022E (pt) 2010-06-11
NO20030068D0 (no) 2003-01-07
ATE462721T1 (de) 2010-04-15
NO330684B1 (no) 2011-06-06
CA2415460C (en) 2011-05-10
AU7252201A (en) 2002-01-21
AU2001272522B2 (en) 2007-05-31
CA2415460A1 (en) 2002-01-17
ZA200300707B (en) 2004-04-15
EP1319022A2 (de) 2003-06-18
JP2004502463A (ja) 2004-01-29
NZ523480A (en) 2008-04-30
WO2002004665A3 (de) 2002-12-19
IL153818A0 (en) 2003-07-31
EP1319022B1 (de) 2010-03-31

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