BR0111915A - 5-aminoalquilpirazolo[4,3-d]pirimidinas - Google Patents

5-aminoalquilpirazolo[4,3-d]pirimidinas

Info

Publication number
BR0111915A
BR0111915A BR0111915-0A BR0111915A BR0111915A BR 0111915 A BR0111915 A BR 0111915A BR 0111915 A BR0111915 A BR 0111915A BR 0111915 A BR0111915 A BR 0111915A
Authority
BR
Brazil
Prior art keywords
pyrimidines
aminoalkylpyrazolo
treatment
aminomethylpyrazolo
aminoalkylpyrazole
Prior art date
Application number
BR0111915-0A
Other languages
English (en)
Portuguese (pt)
Inventor
Rochus Jonas
Pierre Schelling
Maria Christadler
Norbert Beier
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of BR0111915A publication Critical patent/BR0111915A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BR0111915-0A 2000-06-29 2001-06-28 5-aminoalquilpirazolo[4,3-d]pirimidinas BR0111915A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10031584A DE10031584A1 (de) 2000-06-29 2000-06-29 5-Aminoalkyl-pyrazolo[4,3-d]pyrimidine
PCT/EP2001/007378 WO2002000660A1 (de) 2000-06-29 2001-06-28 5-aminoalkyl-pyrazolo[4,3-d]pyrimidine mit phosphodiesterase v inhibierender wirkung

Publications (1)

Publication Number Publication Date
BR0111915A true BR0111915A (pt) 2003-05-13

Family

ID=7647151

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0111915-0A BR0111915A (pt) 2000-06-29 2001-06-28 5-aminoalquilpirazolo[4,3-d]pirimidinas

Country Status (21)

Country Link
US (1) US7060823B2 (https=)
EP (1) EP1296986B1 (https=)
JP (1) JP4964388B2 (https=)
KR (1) KR20030017558A (https=)
CN (1) CN1439011A (https=)
AR (1) AR028772A1 (https=)
AT (1) ATE519761T1 (https=)
AU (2) AU7970001A (https=)
BR (1) BR0111915A (https=)
CA (1) CA2410399C (https=)
CZ (1) CZ20024054A3 (https=)
DE (1) DE10031584A1 (https=)
ES (1) ES2367704T3 (https=)
HU (1) HUP0301587A3 (https=)
MX (1) MXPA02012263A (https=)
NO (1) NO20026247D0 (https=)
PL (1) PL358551A1 (https=)
RU (1) RU2271359C2 (https=)
SK (1) SK17632002A3 (https=)
WO (1) WO2002000660A1 (https=)
ZA (1) ZA200209728B (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19942474A1 (de) * 1999-09-06 2001-03-15 Merck Patent Gmbh Pyrazolo[4,3-d]pyrimidine
DE10031585A1 (de) * 2000-06-29 2002-01-10 Merck Patent Gmbh 2-Aminoalkyl-thieno[2,3-d]pyrimidine
DE10058662A1 (de) * 2000-11-25 2002-05-29 Merck Patent Gmbh Verwendung von Pyrazolo[4,3-d]pyrimidinen
OA13050A (en) 2003-04-29 2006-11-10 Pfizer Ltd 5,7-diaminopyrazolo [4,3-D] pyrimidines useful in the treatment of hypertension.
UA80871C2 (en) * 2003-04-29 2007-11-12 Pfizer Ltd 5,7-diaminopyrazolo[4,3-d]pyrimidines useful in the treatment of hypertension
GB0327319D0 (en) * 2003-11-24 2003-12-24 Pfizer Ltd Novel pharmaceuticals
GB0327323D0 (en) * 2003-11-24 2003-12-31 Pfizer Ltd Novel pharmaceuticals
US7572799B2 (en) 2003-11-24 2009-08-11 Pfizer Inc Pyrazolo[4,3-d]pyrimidines as Phosphodiesterase Inhibitors
CA2562251C (en) * 2004-04-07 2009-04-28 Pfizer Inc. Pyrazolo'4,3-d pyrimidines
EP1809632A2 (en) * 2004-10-28 2007-07-25 Pharmacia & Upjohn Company LLC Pyrazolo[4,3-d]pyrimidine derivatives useful as pde-5 inhibitors
CA2608018C (en) 2005-05-12 2010-07-13 Pfizer Inc. Anhydrous crystalline forms of n-[1-(2-ethoxyethyl)-5-(n-ethyl-n-methylamino)-7-(4-methylpyridin-2-yl-amino)-1h-pyrazolo[4,3-d]pyrimidine-3-carbonyl]methanesulfonamide
NL2000291C2 (nl) 2005-11-10 2009-02-17 Pfizer Prod Inc 1-(1-(2-ethoxyethyl)-3-ethyl-7-(4-methylpyridin-2-ylamino)-1H- pyrazool(4,3-d)pyrimidine-5-yl)piperidine-4-carbonzuur en zouten daarvan.
DE102012200360A1 (de) * 2012-01-11 2013-07-11 Bayer Intellectual Property Gmbh Substituierte Triazine und ihre Verwendung
CA2782774A1 (en) * 2012-07-06 2014-01-06 Pharmascience Inc. Protein kinase inhibitors

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1739850A3 (ru) * 1987-08-31 1992-06-07 Такеда Кемикал Индастриз, Лтд (Фирма) Способ получени конденсированных производных пиразоло[3,4- @ ]пиримидина
US5075310A (en) * 1988-07-01 1991-12-24 Smith Kline & French Laboratories, Ltd. Pyrimidone derivatives as bronchodilators
GB9119704D0 (en) * 1991-09-14 1991-10-30 Pfizer Ltd Therapeutic agents
JP2657760B2 (ja) 1992-07-15 1997-09-24 小野薬品工業株式会社 ４−アミノキナゾリン誘導体およびそれを含有する医薬品
GB9311920D0 (en) * 1993-06-09 1993-07-28 Pfizer Ltd Therapeutic agents
GB9423911D0 (en) 1994-11-26 1995-01-11 Pfizer Ltd Therapeutic agents
US5869486A (en) * 1995-02-24 1999-02-09 Ono Pharmaceutical Co., Ltd. Fused pyrimidines and pyriazines as pharmaceutical compounds
DE19644228A1 (de) * 1996-10-24 1998-04-30 Merck Patent Gmbh Thienopyrimidine
DE19752952A1 (de) * 1997-11-28 1999-06-02 Merck Patent Gmbh Thienopyrimidine
DE19942474A1 (de) * 1999-09-06 2001-03-15 Merck Patent Gmbh Pyrazolo[4,3-d]pyrimidine

Also Published As

Publication number Publication date
US20040029900A1 (en) 2004-02-12
PL358551A1 (en) 2004-08-09
NO20026247L (no) 2002-12-27
ZA200209728B (en) 2004-03-12
MXPA02012263A (es) 2003-04-25
DE10031584A1 (de) 2002-01-10
AR028772A1 (es) 2003-05-21
NO20026247D0 (no) 2002-12-27
CZ20024054A3 (cs) 2003-04-16
JP2004501921A (ja) 2004-01-22
ES2367704T3 (es) 2011-11-07
EP1296986B1 (de) 2011-08-10
AU7970001A (en) 2002-01-08
CN1439011A (zh) 2003-08-27
SK17632002A3 (sk) 2003-05-02
CA2410399A1 (en) 2002-01-03
AU2001279700B2 (en) 2006-08-24
RU2271359C2 (ru) 2006-03-10
US7060823B2 (en) 2006-06-13
ATE519761T1 (de) 2011-08-15
JP4964388B2 (ja) 2012-06-27
KR20030017558A (ko) 2003-03-03
WO2002000660A1 (de) 2002-01-03
HUP0301587A2 (hu) 2003-09-29
HUP0301587A3 (en) 2005-11-28
CA2410399C (en) 2010-02-16
EP1296986A1 (de) 2003-04-02

Similar Documents

Publication Publication Date Title
BR0109703A (pt) Derivados de piperazina
AP1553A (en) Tricyclic inhibitors of poly (ADP-Ribose) polymerases.
BR0111915A (pt) 5-aminoalquilpirazolo[4,3-d]pirimidinas
BG108268A (en) Pyrazolopyrimidines as therapeutic agents
AU3652102A (en) Compounds and their uses
BR0114917A (pt) Inibidores de pirimidina-2,4,6-triona metaloproteinase
BG103417A (en) Condensed pyrimidine bicyclic derivatives
BR0114913A (pt) Inibidores de metaloproteinase de espiro-pirimidina-2,4,6-triona
NZ517758A (en) Pyrazolopyrimidines useful as therapeutic agents
BR0208338A (pt) Derivados de piridina
BG108269A (en) Pyrazolopyrimidines as therapeutic agents
PT911333E (pt) Derivados de pirazolo¬4,3-d|pirimidina e composicoes farmaceuticas que os contenham
MXPA02005844A (es) Inhibidores de cinasas de proteina.
DK1129093T3 (da) Pyrazolopyrimidinonderivater til behandling af impotens
MY121047A (en) Bicyclo [2.2.1] heptanes and related compounds
BRPI0412894A (pt) tienopiridina e furopiridina inibidores de quinases
TR200102338T2 (tr) Siklik ikame edilmiş bağlı pirolokarbazoller ve izoindolonlar.
TR200101357T2 (tr) Parkinson hastalığı, ADHD ve mikroadenomların tedavisi için ilaçlar.
BR0113590A (pt) 7-oxo-piridopirimidinas
BR0109542A (pt) Derivados de imidazopirina alquilados
MXPA04002636A (es) Barra de tocador teniendo un acidificador latente.
PA8487701A1 (es) Derivados de 3,3-biarilpiperidina y 2,2-biarilmorfolina
BR0114379A (pt) Derivados de c-ciclohexilmetilamina substituìdos
BR0013781A (pt) Pirazolo [4,3-d]pirimidinas
PT1362045E (pt) Derivados de imidazole 2-tio substituidos e seu uso na industria farmaceutica

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1963 DE 19.08.2008.