BR0108143A - Derivados heteroaromáticos de carboxamida e seu uso como inibidores da enzima ikk-2 - Google Patents
Derivados heteroaromáticos de carboxamida e seu uso como inibidores da enzima ikk-2Info
- Publication number
- BR0108143A BR0108143A BR0108143-8A BR0108143A BR0108143A BR 0108143 A BR0108143 A BR 0108143A BR 0108143 A BR0108143 A BR 0108143A BR 0108143 A BR0108143 A BR 0108143A
- Authority
- BR
- Brazil
- Prior art keywords
- ikk
- carboxamide
- inhibitors
- enzyme
- heteroaromatic derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D333/40—Thiophene-2-carboxylic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
"DERIVADOS HETEROAROMáTICOS DE CARBOXAMIDA E SEU USO COMO INIBIDORES DA ENZIMA IKK-2". A presente invenção se refere a compostos de carboxamida heteroaromáticos de fórmula (I): em que A, R^ 1^, R^ 2^ e X são como definidos no relatório descritivo, a processos e intermediários usados na sua preparação, a composições farmacêuticas contendo os mesmos e ao seu uso em terapias.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0003154.2A GB0003154D0 (en) | 2000-02-12 | 2000-02-12 | Novel compounds |
PCT/SE2001/000248 WO2001058890A1 (en) | 2000-02-12 | 2001-02-07 | Heteroaromatic carboxamide derivatives and their use as inhibitors of the enzyme ikk-2 |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0108143A true BR0108143A (pt) | 2003-01-21 |
Family
ID=9885396
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0108143-8A BR0108143A (pt) | 2000-02-12 | 2001-02-07 | Derivados heteroaromáticos de carboxamida e seu uso como inibidores da enzima ikk-2 |
Country Status (21)
Country | Link |
---|---|
US (2) | US7358376B2 (pt) |
EP (1) | EP1261600B1 (pt) |
JP (1) | JP4812999B2 (pt) |
KR (1) | KR100738165B1 (pt) |
CN (1) | CN1243747C (pt) |
AT (1) | ATE266019T1 (pt) |
AU (1) | AU781047B2 (pt) |
BR (1) | BR0108143A (pt) |
CA (1) | CA2396824C (pt) |
DE (1) | DE60103132T2 (pt) |
DK (1) | DK1261600T3 (pt) |
ES (1) | ES2218376T3 (pt) |
GB (1) | GB0003154D0 (pt) |
IL (2) | IL150482A0 (pt) |
MX (1) | MXPA02007734A (pt) |
NO (1) | NO327741B1 (pt) |
NZ (1) | NZ519947A (pt) |
PT (1) | PT1261600E (pt) |
TR (1) | TR200401962T4 (pt) |
WO (1) | WO2001058890A1 (pt) |
ZA (1) | ZA200205300B (pt) |
Families Citing this family (61)
Publication number | Priority date | Publication date | Assignee | Title |
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US6869956B2 (en) | 2000-10-03 | 2005-03-22 | Bristol-Myers Squibb Company | Methods of treating inflammatory and immune diseases using inhibitors of IκB kinase (IKK) |
JP2004523476A (ja) * | 2000-10-12 | 2004-08-05 | スミスクライン・ビーチャム・コーポレイション | NF−κB阻害剤 |
US6846834B2 (en) | 2000-10-26 | 2005-01-25 | Amgen Inc. | Antiinflammation agents |
HUP0304045A3 (en) * | 2001-02-01 | 2005-05-30 | Bristol Myers Squibb Company P | Use of ikb-kinase inhibitors for treating of inflammatory and immune diseases and pharmaceutical compositions containing them |
AP1753A (en) * | 2001-06-11 | 2007-07-18 | Shire Biochem Inc | Thiophene derivatives as antiviral agents for flavvivirus infection |
US8329924B2 (en) * | 2001-06-11 | 2012-12-11 | Vertex Pharmaceuticals (Canada) Incorporated | Compounds and methods for the treatment or prevention of Flavivirus infections |
SE0102616D0 (sv) * | 2001-07-25 | 2001-07-25 | Astrazeneca Ab | Novel compounds |
CA2460942A1 (en) | 2001-09-19 | 2003-03-27 | Pharmacia Corporation | Substituted pyrazolyl compounds for the treatment of inflammation |
JP2005504806A (ja) * | 2001-09-21 | 2005-02-17 | スミスクライン・ビーチャム・コーポレイション | 化合物 |
JP2006515828A (ja) | 2001-09-27 | 2006-06-08 | スミスクライン・ビーチャム・コーポレイション | 化学化合物 |
WO2003028731A1 (en) * | 2001-10-04 | 2003-04-10 | Smithkline Beecham Corporation | Chk1 kinase inhibitors |
WO2003029242A1 (en) * | 2001-10-04 | 2003-04-10 | Smithkline Beecham Corporation | NF-λB INHIBITORS |
EP1444010A2 (en) * | 2001-10-30 | 2004-08-11 | Pharmacia Corporation | Heteroaromatic carboxamide derivatives for the treatment of inflammation |
US7176314B2 (en) | 2001-12-05 | 2007-02-13 | Amgen, Inc. | Inflammation modulators |
US7375131B2 (en) | 2002-06-06 | 2008-05-20 | Smithklinebeecham Corp. | NF-κB inhibitors |
US6974870B2 (en) | 2002-06-06 | 2005-12-13 | Boehringer Ingelheim Phamaceuticals, Inc. | Substituted 3-amino-thieno [2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses |
EP1513516B1 (en) | 2002-06-06 | 2008-12-03 | Boehringer Ingelheim Pharmaceuticals Inc. | SUBSTITUTED 3-AMINO-THIENO(2,3-b) PYRIDINE-2-CARBOXYLIC ACID AMIDE COMPOUNDS AND PROCESSES FOR PREPARING AND THEIR USES |
US7179836B2 (en) | 2002-09-20 | 2007-02-20 | Smithkline Beecham Corporation | Chemical compounds |
AU2003270701B2 (en) | 2002-10-31 | 2009-11-12 | Amgen Inc. | Antiinflammation agents |
US7196106B2 (en) | 2002-11-05 | 2007-03-27 | Merck & Co., Inc | Cyanothiophene derivatives, compositions containing such compounds and methods of use |
JP2006510676A (ja) * | 2002-12-06 | 2006-03-30 | スミスクライン・ビーチャム・コーポレイション | NF−κB阻害剤 |
KR101058696B1 (ko) * | 2002-12-10 | 2011-08-22 | 바이로켐 파마 인코포레이티드 | 후라비바이러스 감염의 치료 또는 예방을 위한 화합물과방법 |
SE0300091D0 (sv) | 2003-01-15 | 2003-01-15 | Astrazeneca Ab | Novel compounds |
SE0300092D0 (sv) * | 2003-01-15 | 2003-01-15 | Astrazeneca Ab | Novel compounds |
RU2006107782A (ru) | 2003-08-15 | 2006-08-10 | Астразенека Аб (Se) | Замещенные тиофены и их применение |
US20050085531A1 (en) * | 2003-10-03 | 2005-04-21 | Hodge Carl N. | Thiophene-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof |
EP1678164B1 (en) * | 2003-10-14 | 2007-04-11 | Pharmacia Corporation | Substituted pyrazinone compounds for the treatment of inflammation |
WO2005037797A1 (en) * | 2003-10-21 | 2005-04-28 | Pharmacia Corporation | Substituted pyrazole urea compounds for the treatment of inflammation |
BRPI0418351A (pt) * | 2004-01-05 | 2007-05-08 | Astrazeneca Ab | composto ou um sal farmaceuticamente aceitável do mesmo, métodos de limitar a proliferação celular em um humano ou animal, de tratamento de um humano ou animal sofrendo de cáncer, de tratamento de profilaxia de cáncer, de tratamento de um humano ou animal sofrendo de uma doença neoplásica, de tratamento de um humano ou animal sofrendo de uma doença prolifetativa de tratamento de cáncer, para o tratamento de infecções associadas com cáncer, para o tratamento profilático de infecções associadas com cáncer, composição farmacêutica, uso de um composto ou um sal farmaceuticamente aceitável do mesmo, método de inibir a chk1 quinase, e, processo para a preparação de um composto ou um sal farmaceuticamente aceitável do mesmo |
BRPI0509795A (pt) * | 2004-04-12 | 2007-10-23 | Sankyo Co | composto ou um sal farmacologicamente aceitável do mesmo, composição farmacêutica, uso do composto ou sal farmacologicamente aceitável do mesmo, e, método para promover osteogênese, supressão de ressorção óssea e/ou melhoramento da densidade óssea |
WO2005105777A1 (en) * | 2004-05-05 | 2005-11-10 | Pharmacia & Upjohn Company Llc | Substituted thiophene amide compounds for the treatment of inflammation |
AR050253A1 (es) | 2004-06-24 | 2006-10-11 | Smithkline Beecham Corp | Compuesto derivado de indazol carboxamida, composicion que lo comprende y su uso para la preparacion de un medicamento |
TW200626142A (en) | 2004-09-21 | 2006-08-01 | Glaxo Group Ltd | Chemical compounds |
WO2006036031A1 (ja) * | 2004-09-30 | 2006-04-06 | Takeda Pharmaceutical Company Limited | 縮合フラン誘導体およびその用途 |
EP1876179B1 (en) | 2005-04-28 | 2015-03-25 | Takeda Pharmaceutical Company Limited | Thienopyrimidone compounds |
US8063071B2 (en) | 2007-10-31 | 2011-11-22 | GlaxoSmithKline, LLC | Chemical compounds |
AU2006266028B2 (en) | 2005-06-30 | 2012-03-15 | Smithkline Beecham Corporation | Chemical compounds |
JP2009539865A (ja) | 2006-06-06 | 2009-11-19 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 置換3−アミノ−チエノ[2,3−b]ピリジン2−カルボン酸アミド化合物及び製造方法及びそれらの使用 |
EA201101492A1 (ru) * | 2006-11-15 | 2012-09-28 | Вирокем Фарма Инк. | Аналоги тиофена для лечения или предупреждения флавивирусных инфекций |
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AR065804A1 (es) | 2007-03-23 | 2009-07-01 | Smithkline Beecham Corp | Compuesto de indol carboxamida, composicion farmaceutica que lo comprende y uso de dicho compuesto para preparar un medicamento |
GB0709031D0 (en) | 2007-05-10 | 2007-06-20 | Sareum Ltd | Pharmaceutical compounds |
CN104491864A (zh) | 2008-04-21 | 2015-04-08 | 奥德纳米有限公司 | 用于治疗耳部疾病和病况的耳用调配物及方法 |
US11969501B2 (en) | 2008-04-21 | 2024-04-30 | Dompé Farmaceutici S.P.A. | Auris formulations for treating otic diseases and conditions |
US8445529B2 (en) | 2008-07-14 | 2013-05-21 | Santen Pharmaceutical Co., Ltd. | Indole derivative having, carbamoyl group, ureido group and substituted oxy group |
KR20110044767A (ko) | 2008-08-25 | 2011-04-29 | 산텐 세이야꾸 가부시키가이샤 | 우레이도기, 아미노카르보닐기 및 치환기를 가져도 좋은 2환식기를 치환기로서 갖는 신규 피롤 유도체 |
JP2010077119A (ja) * | 2008-08-25 | 2010-04-08 | Santen Pharmaceut Co Ltd | ウレイド基、アミノカルボニル基及び置換フェニル基を置換基として有するピロール誘導体を有効成分として含有する骨・関節疾患の予防又は治療剤 |
MY150568A (en) * | 2008-11-14 | 2014-01-30 | Du Pont | Method for preparing a non-hydratable crystal form |
US8354539B2 (en) | 2009-03-10 | 2013-01-15 | Glaxo Group Limited | Indole derivatives as IKK2 inhibitors |
GB0913345D0 (en) | 2009-07-31 | 2009-09-16 | Astrazeneca Ab | New combination 802 |
WO2011061527A1 (en) | 2009-11-17 | 2011-05-26 | Astrazeneca Ab | Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases |
GB201016912D0 (en) | 2010-10-07 | 2010-11-24 | Astrazeneca Ab | Novel combination |
WO2012046793A1 (ja) * | 2010-10-07 | 2012-04-12 | 参天製薬株式会社 | ウレイド基とアミノカルボニル基を置換基として有するチオフェン誘導体を有効成分として含有する新規jak3阻害剤 |
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GB201021992D0 (en) | 2010-12-23 | 2011-02-02 | Astrazeneca Ab | Compound |
EP2520292A1 (en) | 2011-05-06 | 2012-11-07 | Helmholtz-Zentrum für Infektionsforschung GmbH | Use of spirangiens for the treatment or prevention of IL-8 or IL-6 mediated disorders |
GB201202027D0 (en) | 2012-02-06 | 2012-03-21 | Sareum Ltd | Pharmaceutical compounds |
EP2634185B1 (en) | 2012-03-02 | 2016-01-13 | Sareum Limited | TYK2 kinase inhibitors |
AU2017290256A1 (en) | 2016-06-29 | 2019-01-17 | Otonomy, Inc. | Triglyceride otic formulations and uses thereof |
GB201617871D0 (en) | 2016-10-21 | 2016-12-07 | Sareum Limited | Pharmaceutical compounds |
US11000491B2 (en) | 2017-05-05 | 2021-05-11 | Hepanova, Inc. | Amino-aryl-benzamide compounds and methods of use thereof |
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GB1468012A (en) | 1973-08-09 | 1977-03-23 | Beecham Group Ltd | 2-amino-3-carboxy-thiophene derivatives |
DE3529247A1 (de) * | 1985-05-17 | 1986-11-20 | Bayer Ag, 5090 Leverkusen | Verwendung von thienylharnstoffen und -isoharnstoffen als leistungsfoerdernde mittel bei tieren, neue thienylharnstoffe und -isoharnstoffe und ihre herstellung |
US5258357A (en) * | 1989-10-07 | 1993-11-02 | Basf Aktiengesellschaft | Carboxamides, their preparation and their use as herbicides |
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US5571810A (en) * | 1990-06-11 | 1996-11-05 | Fujisawa Pharmaceutical Co., Ltd. | Thiophene derivatives |
WO1998002430A1 (en) * | 1996-07-11 | 1998-01-22 | Pfizer Pharmaceuticals Inc. | Pyridylpyrrole compounds useful as interleukin- and tnf antagonists |
PT853083E (pt) * | 1997-01-06 | 2001-12-28 | Pfizer | Composto de piridilfurano e piridiltiofeno e sua utilizacao farmaceutica |
US6037340A (en) | 1997-05-28 | 2000-03-14 | Cadus Pharmaceutical Corporation | Synthesis and use of thiophene- and pyrrole-based heteroaromatic compounds |
DE19744026A1 (de) * | 1997-10-06 | 1999-04-08 | Hoechst Marion Roussel De Gmbh | Pyrazol-Derivate, ihre Herstellung und ihre Verwendung in Arzneimitteln |
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HN2000000051A (es) | 1999-05-19 | 2001-02-02 | Pfizer Prod Inc | Derivados heterociclicos utiles como agentes anticancerosos |
US6414013B1 (en) | 2000-06-19 | 2002-07-02 | Pharmacia & Upjohn S.P.A. | Thiophene compounds, process for preparing the same, and pharmaceutical compositions containing the same background of the invention |
JP2004523476A (ja) * | 2000-10-12 | 2004-08-05 | スミスクライン・ビーチャム・コーポレイション | NF−κB阻害剤 |
US20040024047A1 (en) * | 2001-10-12 | 2004-02-05 | Callahan James F. | Nf-kb inhibitors |
SE0102616D0 (sv) * | 2001-07-25 | 2001-07-25 | Astrazeneca Ab | Novel compounds |
SE0102617D0 (sv) * | 2001-07-25 | 2001-07-25 | Astrazeneca Ab | Novel compounds |
WO2003029242A1 (en) * | 2001-10-04 | 2003-04-10 | Smithkline Beecham Corporation | NF-λB INHIBITORS |
SE0300091D0 (sv) * | 2003-01-15 | 2003-01-15 | Astrazeneca Ab | Novel compounds |
-
2000
- 2000-02-12 GB GBGB0003154.2A patent/GB0003154D0/en not_active Ceased
-
2001
- 2001-02-07 US US09/868,884 patent/US7358376B2/en not_active Expired - Fee Related
- 2001-02-07 PT PT01902951T patent/PT1261600E/pt unknown
- 2001-02-07 ES ES01902951T patent/ES2218376T3/es not_active Expired - Lifetime
- 2001-02-07 EP EP01902951A patent/EP1261600B1/en not_active Expired - Lifetime
- 2001-02-07 MX MXPA02007734A patent/MXPA02007734A/es active IP Right Grant
- 2001-02-07 DE DE60103132T patent/DE60103132T2/de not_active Expired - Lifetime
- 2001-02-07 KR KR1020027010124A patent/KR100738165B1/ko not_active IP Right Cessation
- 2001-02-07 TR TR2004/01962T patent/TR200401962T4/xx unknown
- 2001-02-07 BR BR0108143-8A patent/BR0108143A/pt not_active Application Discontinuation
- 2001-02-07 CN CNB018046606A patent/CN1243747C/zh not_active Expired - Fee Related
- 2001-02-07 AT AT01902951T patent/ATE266019T1/de active
- 2001-02-07 JP JP2001558440A patent/JP4812999B2/ja not_active Expired - Fee Related
- 2001-02-07 WO PCT/SE2001/000248 patent/WO2001058890A1/en active IP Right Grant
- 2001-02-07 NZ NZ519947A patent/NZ519947A/en not_active IP Right Cessation
- 2001-02-07 DK DK01902951T patent/DK1261600T3/da active
- 2001-02-07 CA CA2396824A patent/CA2396824C/en not_active Expired - Fee Related
- 2001-02-07 IL IL15048201A patent/IL150482A0/xx active IP Right Grant
- 2001-02-07 AU AU30705/01A patent/AU781047B2/en not_active Ceased
-
2002
- 2002-06-27 IL IL150482A patent/IL150482A/en not_active IP Right Cessation
- 2002-07-02 ZA ZA200205300A patent/ZA200205300B/en unknown
- 2002-08-09 NO NO20023786A patent/NO327741B1/no not_active IP Right Cessation
-
2007
- 2007-12-03 US US11/949,273 patent/US20090181962A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE60103132D1 (de) | 2004-06-09 |
NO327741B1 (no) | 2009-09-14 |
JP4812999B2 (ja) | 2011-11-09 |
IL150482A (en) | 2006-08-01 |
KR20030005183A (ko) | 2003-01-17 |
GB0003154D0 (en) | 2000-04-05 |
MXPA02007734A (es) | 2002-10-11 |
CA2396824A1 (en) | 2001-08-16 |
EP1261600A1 (en) | 2002-12-04 |
DE60103132T2 (de) | 2005-05-12 |
US20020107252A1 (en) | 2002-08-08 |
US7358376B2 (en) | 2008-04-15 |
US20090181962A1 (en) | 2009-07-16 |
NO20023786D0 (no) | 2002-08-09 |
IL150482A0 (en) | 2002-12-01 |
JP2003522766A (ja) | 2003-07-29 |
AU3070501A (en) | 2001-08-20 |
WO2001058890A1 (en) | 2001-08-16 |
ATE266019T1 (de) | 2004-05-15 |
CN1425012A (zh) | 2003-06-18 |
NO20023786L (no) | 2002-09-23 |
CA2396824C (en) | 2010-11-16 |
CN1243747C (zh) | 2006-03-01 |
TR200401962T4 (tr) | 2004-09-21 |
AU781047B2 (en) | 2005-05-05 |
DK1261600T3 (da) | 2004-08-16 |
EP1261600B1 (en) | 2004-05-06 |
PT1261600E (pt) | 2004-08-31 |
ZA200205300B (en) | 2003-10-02 |
KR100738165B1 (ko) | 2007-07-10 |
NZ519947A (en) | 2004-05-28 |
ES2218376T3 (es) | 2004-11-16 |
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