BR0012840A - Processo para a hidrogenação catalìtica cis-seletiva de ciclohexilidenaminas - Google Patents

Processo para a hidrogenação catalìtica cis-seletiva de ciclohexilidenaminas

Info

Publication number
BR0012840A
BR0012840A BR0012840-6A BR0012840A BR0012840A BR 0012840 A BR0012840 A BR 0012840A BR 0012840 A BR0012840 A BR 0012840A BR 0012840 A BR0012840 A BR 0012840A
Authority
BR
Brazil
Prior art keywords
cis
cyclohexylidenamines
catalytically
selective hydrogenation
selective
Prior art date
Application number
BR0012840-6A
Other languages
English (en)
Inventor
Heinz Steiner
Marc Thommen
Hans-Peter Jalett
Markus Benz
Original Assignee
Ciba Sc Holding Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Sc Holding Ag filed Critical Ciba Sc Holding Ag
Publication of BR0012840A publication Critical patent/BR0012840A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/24—Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds
    • C07C209/26—Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds by reduction with hydrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/44—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
    • C07C209/52—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of imines or imino-ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

"PROCESSO PARA A HIDROGENAçãO CATALìTICA CIS-SELETIVA DE CICLOHEXILIDENAMINAS". A invenção refere-se a um processo para a preparação cis seletiva de aminas cíclicas do tipo sertralina por alquilção redutora de iminas cíclicas ou de seus respectivos precursores, e a hidrogenação catalítica na presença de um catalisador contendo cobre e na presença de um solvente prótico.
BR0012840-6A 1999-07-29 2000-07-20 Processo para a hidrogenação catalìtica cis-seletiva de ciclohexilidenaminas BR0012840A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH139999 1999-07-29
PCT/EP2000/006932 WO2001009080A1 (en) 1999-07-29 2000-07-20 Process for the cis-selective catalytic hydrogenation of cyclohexylidenamines

Publications (1)

Publication Number Publication Date
BR0012840A true BR0012840A (pt) 2002-05-28

Family

ID=4209524

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0012840-6A BR0012840A (pt) 1999-07-29 2000-07-20 Processo para a hidrogenação catalìtica cis-seletiva de ciclohexilidenaminas

Country Status (18)

Country Link
US (2) US6720454B1 (pt)
EP (1) EP1200387B1 (pt)
JP (1) JP2003506346A (pt)
CN (1) CN1213991C (pt)
AR (1) AR024965A1 (pt)
AT (1) ATE264831T1 (pt)
AU (1) AU6275900A (pt)
BR (1) BR0012840A (pt)
DE (1) DE60010090T2 (pt)
DK (1) DK1200387T3 (pt)
ES (1) ES2216923T3 (pt)
HU (1) HUP0201987A3 (pt)
IL (2) IL147451A0 (pt)
MX (1) MXPA02000867A (pt)
PT (1) PT1200387E (pt)
TR (1) TR200200110T2 (pt)
TW (1) TW526184B (pt)
WO (1) WO2001009080A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR200200110T2 (tr) * 1999-07-29 2002-06-21 Ciba Specialty Chemicals Holding Inc. Sikloheksilidenaminlerin cis-selektif katalitik hidrojenasyonu için süreç
US6723878B2 (en) 2001-06-15 2004-04-20 Orion Corporation Fermion Method for preparing sertraline
US7276629B2 (en) 2003-04-14 2007-10-02 Teva Pharmaceutical Industries Ltd. Hydrogenation of imine intermediates of sertraline with catalysts
US7531752B2 (en) * 2003-07-24 2009-05-12 Nec Corporation Flexible substrate and electronic device
CN101462964A (zh) * 2007-12-19 2009-06-24 北京德众万全药物技术开发有限公司 一种舍曲林关键中间体的制备方法
KR20100108393A (ko) 2007-12-21 2010-10-06 바스프 에스이 키랄 이민의 부분입체 선택적 전환 방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536518A (en) * 1979-11-01 1985-08-20 Pfizer Inc. Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
GB9114948D0 (en) * 1991-07-11 1991-08-28 Pfizer Ltd Process for preparing sertraline intermediates
ES2093848T3 (es) 1991-12-13 1997-01-01 Pfizer Procedimiento para la preparacion de enantiomeros de cetonas.
HU222341B1 (hu) * 1996-12-18 2003-06-28 Richter Gedeon Vegyészeti Gyár Rt. Eljárás sertralin előállítására és az eljárásban alkalmazott intermedier
US6232501B1 (en) * 1998-03-18 2001-05-15 Ciba Specialty Chemicals Corporation Process for the cis-selective catalytic hydrogenation of cyclohexylidenamines
TR200200110T2 (tr) * 1999-07-29 2002-06-21 Ciba Specialty Chemicals Holding Inc. Sikloheksilidenaminlerin cis-selektif katalitik hidrojenasyonu için süreç

Also Published As

Publication number Publication date
WO2001009080A1 (en) 2001-02-08
ATE264831T1 (de) 2004-05-15
HUP0201987A2 (en) 2002-09-28
EP1200387A1 (en) 2002-05-02
CN1213991C (zh) 2005-08-10
ES2216923T3 (es) 2004-11-01
AR024965A1 (es) 2002-10-30
JP2003506346A (ja) 2003-02-18
IL147451A0 (en) 2002-08-14
IL147451A (en) 2007-08-19
TW526184B (en) 2003-04-01
DK1200387T3 (da) 2004-07-19
AU6275900A (en) 2001-02-19
HUP0201987A3 (en) 2004-03-01
MXPA02000867A (es) 2002-07-30
PT1200387E (pt) 2004-09-30
TR200200110T2 (tr) 2002-06-21
US20040171883A1 (en) 2004-09-02
DE60010090T2 (de) 2005-03-31
US6720454B1 (en) 2004-04-13
US6900355B2 (en) 2005-05-31
EP1200387B1 (en) 2004-04-21
CN1365350A (zh) 2002-08-21
DE60010090D1 (de) 2004-05-27

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements