DE60010090D1 - Verfahren zur cis-selektiven katalytischen hydrierung von cyclohexylidenaminen - Google Patents

Verfahren zur cis-selektiven katalytischen hydrierung von cyclohexylidenaminen

Info

Publication number
DE60010090D1
DE60010090D1 DE60010090T DE60010090T DE60010090D1 DE 60010090 D1 DE60010090 D1 DE 60010090D1 DE 60010090 T DE60010090 T DE 60010090T DE 60010090 T DE60010090 T DE 60010090T DE 60010090 D1 DE60010090 D1 DE 60010090D1
Authority
DE
Germany
Prior art keywords
cyclohexylidenamines
selective catalytic
catalytic hydration
cis
cis selective
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60010090T
Other languages
English (en)
Other versions
DE60010090T2 (de
Inventor
Heinz Steiner
Marc Thommen
Hans-Peter Jalett
Markus Benz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Pharmaceutical Industries Ltd
Original Assignee
Ciba Spezialitaetenchemie Holding AG
Ciba SC Holding AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Spezialitaetenchemie Holding AG, Ciba SC Holding AG filed Critical Ciba Spezialitaetenchemie Holding AG
Application granted granted Critical
Publication of DE60010090D1 publication Critical patent/DE60010090D1/de
Publication of DE60010090T2 publication Critical patent/DE60010090T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/24—Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds
    • C07C209/26—Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds by reduction with hydrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/44—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
    • C07C209/52—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of imines or imino-ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE60010090T 1999-07-29 2000-07-20 Verfahren zur cis-selektiven katalytischen hydrierung von cyclohexylidenaminen Expired - Lifetime DE60010090T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH139999 1999-07-29
CH139999 1999-07-29
PCT/EP2000/006932 WO2001009080A1 (en) 1999-07-29 2000-07-20 Process for the cis-selective catalytic hydrogenation of cyclohexylidenamines

Publications (2)

Publication Number Publication Date
DE60010090D1 true DE60010090D1 (de) 2004-05-27
DE60010090T2 DE60010090T2 (de) 2005-03-31

Family

ID=4209524

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60010090T Expired - Lifetime DE60010090T2 (de) 1999-07-29 2000-07-20 Verfahren zur cis-selektiven katalytischen hydrierung von cyclohexylidenaminen

Country Status (18)

Country Link
US (2) US6720454B1 (de)
EP (1) EP1200387B1 (de)
JP (1) JP2003506346A (de)
CN (1) CN1213991C (de)
AR (1) AR024965A1 (de)
AT (1) ATE264831T1 (de)
AU (1) AU6275900A (de)
BR (1) BR0012840A (de)
DE (1) DE60010090T2 (de)
DK (1) DK1200387T3 (de)
ES (1) ES2216923T3 (de)
HU (1) HUP0201987A3 (de)
IL (2) IL147451A0 (de)
MX (1) MXPA02000867A (de)
PT (1) PT1200387E (de)
TR (1) TR200200110T2 (de)
TW (1) TW526184B (de)
WO (1) WO2001009080A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR200200110T2 (tr) * 1999-07-29 2002-06-21 Ciba Specialty Chemicals Holding Inc. Sikloheksilidenaminlerin cis-selektif katalitik hidrojenasyonu için süreç
US6723878B2 (en) 2001-06-15 2004-04-20 Orion Corporation Fermion Method for preparing sertraline
US7276629B2 (en) 2003-04-14 2007-10-02 Teva Pharmaceutical Industries Ltd. Hydrogenation of imine intermediates of sertraline with catalysts
US7531752B2 (en) * 2003-07-24 2009-05-12 Nec Corporation Flexible substrate and electronic device
CN101462964A (zh) * 2007-12-19 2009-06-24 北京德众万全药物技术开发有限公司 一种舍曲林关键中间体的制备方法
KR20100108393A (ko) 2007-12-21 2010-10-06 바스프 에스이 키랄 이민의 부분입체 선택적 전환 방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536518A (en) * 1979-11-01 1985-08-20 Pfizer Inc. Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
GB9114948D0 (en) * 1991-07-11 1991-08-28 Pfizer Ltd Process for preparing sertraline intermediates
ES2093848T3 (es) 1991-12-13 1997-01-01 Pfizer Procedimiento para la preparacion de enantiomeros de cetonas.
HU222341B1 (hu) * 1996-12-18 2003-06-28 Richter Gedeon Vegyészeti Gyár Rt. Eljárás sertralin előállítására és az eljárásban alkalmazott intermedier
US6232501B1 (en) * 1998-03-18 2001-05-15 Ciba Specialty Chemicals Corporation Process for the cis-selective catalytic hydrogenation of cyclohexylidenamines
TR200200110T2 (tr) * 1999-07-29 2002-06-21 Ciba Specialty Chemicals Holding Inc. Sikloheksilidenaminlerin cis-selektif katalitik hidrojenasyonu için süreç

Also Published As

Publication number Publication date
WO2001009080A1 (en) 2001-02-08
ATE264831T1 (de) 2004-05-15
HUP0201987A2 (en) 2002-09-28
EP1200387A1 (de) 2002-05-02
CN1213991C (zh) 2005-08-10
ES2216923T3 (es) 2004-11-01
AR024965A1 (es) 2002-10-30
JP2003506346A (ja) 2003-02-18
IL147451A0 (en) 2002-08-14
IL147451A (en) 2007-08-19
TW526184B (en) 2003-04-01
DK1200387T3 (da) 2004-07-19
BR0012840A (pt) 2002-05-28
AU6275900A (en) 2001-02-19
HUP0201987A3 (en) 2004-03-01
MXPA02000867A (es) 2002-07-30
PT1200387E (pt) 2004-09-30
TR200200110T2 (tr) 2002-06-21
US20040171883A1 (en) 2004-09-02
DE60010090T2 (de) 2005-03-31
US6720454B1 (en) 2004-04-13
US6900355B2 (en) 2005-05-31
EP1200387B1 (de) 2004-04-21
CN1365350A (zh) 2002-08-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: CIBA HOLDING INC., BASEL, CH

8327 Change in the person/name/address of the patent owner

Owner name: TEVA PHARMACEUTICAL INDUSTRIES LTD., PETAH TIQ, IL