BR0007174A - Composto, preparação farmacêutica e uso de compostos - Google Patents
Composto, preparação farmacêutica e uso de compostosInfo
- Publication number
- BR0007174A BR0007174A BR0007174-9A BR0007174A BR0007174A BR 0007174 A BR0007174 A BR 0007174A BR 0007174 A BR0007174 A BR 0007174A BR 0007174 A BR0007174 A BR 0007174A
- Authority
- BR
- Brazil
- Prior art keywords
- compounds
- compound
- pharmaceutical preparation
- preparation
- prodrugs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A61P25/10—Antiepileptics; Anticonvulsants for petit-mal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19946289A DE19946289A1 (de) | 1999-09-28 | 1999-09-28 | Benzodiazepin-Derivate, deren Herstellung und Anwendung |
DE10039610A DE10039610A1 (de) | 2000-08-09 | 2000-08-09 | Azepinoindol-Derivate, deren Herstellung und Anwendung |
PCT/EP2000/009024 WO2001023390A2 (de) | 1999-09-28 | 2000-09-15 | Azepinoindol-derivate, deren herstellung und anwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0007174A true BR0007174A (pt) | 2001-09-04 |
Family
ID=26006691
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0007174-9A BR0007174A (pt) | 1999-09-28 | 2000-09-15 | Composto, preparação farmacêutica e uso de compostos |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP1183259A2 (de) |
JP (1) | JP2003510328A (de) |
KR (1) | KR20010087401A (de) |
CN (1) | CN1374961A (de) |
AU (1) | AU1271201A (de) |
BG (1) | BG105650A (de) |
BR (1) | BR0007174A (de) |
CA (1) | CA2352194A1 (de) |
CZ (1) | CZ20012373A3 (de) |
HK (1) | HK1048999A1 (de) |
HU (1) | HUP0104917A3 (de) |
IL (1) | IL143349A0 (de) |
NO (1) | NO20012567L (de) |
PL (1) | PL347885A1 (de) |
SK (1) | SK8842001A3 (de) |
TR (1) | TR200101499T1 (de) |
WO (1) | WO2001023390A2 (de) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1140936B1 (de) | 1999-01-11 | 2004-03-17 | Agouron Pharmaceuticals, Inc. | Tricyclische inhibitoren von poly(adp-ribose) polymerasen |
US7151102B2 (en) | 2000-10-30 | 2006-12-19 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
EP1339402B1 (de) | 2000-12-01 | 2010-08-25 | Eisai Inc. | Azaphenanthridone-derivate und deren verwendung als parp-inhibitoren |
US7026311B2 (en) * | 2002-01-10 | 2006-04-11 | Abbott Gmbh & Co., Kg | Dibenzodiazepine derivatives, their preparation and use |
ES2357057T3 (es) | 2002-04-30 | 2011-04-15 | Kudos Pharmaceuticals Limited | Derivados de ftalazinona. |
ATE546539T1 (de) | 2002-07-26 | 2012-03-15 | Basf Plant Science Gmbh | Revertierung der negativ-selektiven wirkung von negativen markerproteinen als selektionsverfahren |
US7449464B2 (en) | 2003-03-12 | 2008-11-11 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
GB0305681D0 (en) | 2003-03-12 | 2003-04-16 | Kudos Pharm Ltd | Phthalazinone derivatives |
US7223759B2 (en) | 2003-09-15 | 2007-05-29 | Anadys Pharmaceuticals, Inc. | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds |
SG150548A1 (en) | 2003-12-01 | 2009-03-30 | Kudos Pharm Ltd | Dna damage repair inhibitors for treatment of cancer |
US7781478B2 (en) | 2004-07-14 | 2010-08-24 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
US7772271B2 (en) | 2004-07-14 | 2010-08-10 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
WO2006019831A1 (en) | 2004-07-14 | 2006-02-23 | Ptc Therapeutics, Inc. | Methods for treating hepatitis c |
US7868037B2 (en) | 2004-07-14 | 2011-01-11 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
JP2008507518A (ja) | 2004-07-22 | 2008-03-13 | ピーティーシー セラピューティクス,インコーポレーテッド | C型肝炎を治療するためのチエノピリジン |
ATE541043T1 (de) | 2005-03-08 | 2012-01-15 | Basf Plant Science Gmbh | Expressionsverstärkende intron-sequenz |
US7662824B2 (en) | 2005-03-18 | 2010-02-16 | Janssen Pharmaceutica Nv | Acylhydrazones as kinase modulators |
GB0521373D0 (en) | 2005-10-20 | 2005-11-30 | Kudos Pharm Ltd | Pthalazinone derivatives |
UY30639A1 (es) | 2006-10-17 | 2008-05-31 | Kudos Pharm Ltd | Derivados sustituidos de 2h-ftalazin-1-ona, sus formas cristalinas, proceso de preparacion y aplicaciones |
KR20100059950A (ko) | 2007-09-14 | 2010-06-04 | 아스트라제네카 아베 | 프탈라지논 유도체 |
UY31603A1 (es) | 2008-01-23 | 2009-08-31 | Derivados de ftalazinona | |
GB0804755D0 (en) * | 2008-03-14 | 2008-04-16 | Angeletti P Ist Richerche Bio | Therapeutic compounds |
CN102238945B (zh) | 2008-10-07 | 2014-10-29 | 阿斯利康(英国)有限公司 | 药物制剂514 |
WO2011058367A2 (en) | 2009-11-13 | 2011-05-19 | Astrazeneca Ab | Diagnostic test for predicting responsiveness to treatment with poly(adp-ribose) polymerase (parp) inhibitor |
JP5922029B2 (ja) | 2009-11-27 | 2016-05-24 | ビーエーエスエフ プラント サイエンス カンパニー ゲーエムベーハー | キメラエンドヌクレアーゼおよびその使用 |
AU2010325549B2 (en) | 2009-11-27 | 2017-04-20 | Basf Plant Science Company Gmbh | Optimized endonucleases and uses thereof |
WO2011064751A1 (en) | 2009-11-27 | 2011-06-03 | Basf Plant Science Company Gmbh | Chimeric endonucleases and uses thereof |
NZ604035A (en) | 2010-06-04 | 2015-02-27 | Albany Molecular Res Inc | Glycine transporter-1 inhibitors, methods of making them, and uses thereof |
KR101896567B1 (ko) | 2015-07-23 | 2018-09-07 | 인스티튜트 큐리 | 암 치료를 위한 디베이트 분자와 parp 억제제의 병용 용도 |
GB201519573D0 (en) | 2015-11-05 | 2015-12-23 | King S College London | Combination |
WO2018162439A1 (en) | 2017-03-08 | 2018-09-13 | Onxeo | New predictive biomarker for the sensitivity to a treatment of cancer with a dbait molecule |
WO2018197461A1 (en) | 2017-04-28 | 2018-11-01 | Akribes Biomedical Gmbh | A parp inhibitor in combination with a glucocorticoid and/or ascorbic acid and/or a protein growth factor for the treatment of impaired wound healing |
WO2018218025A1 (en) * | 2017-05-24 | 2018-11-29 | The Trustees Of The University Of Pennsylvania | Radiolabeled and fluorescent parp inhibitors for imaging and radiotherapy |
EP3765613A1 (de) | 2018-03-13 | 2021-01-20 | Onxeo | Dbait-molekül gegen erworbene resistenz in der behandlung von krebs |
US11034669B2 (en) | 2018-11-30 | 2021-06-15 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
KR20210125024A (ko) * | 2019-02-02 | 2021-10-15 | 치아타이 티안큉 파마수티컬 그룹 주식회사 | Parp 억제제로서의 인돌로 헵타밀 옥심 유사체 |
CN114072410B (zh) * | 2019-08-01 | 2023-08-01 | 正大天晴药业集团股份有限公司 | 作为parp抑制剂吲哚并七元酰肟化合物 |
GB201913030D0 (en) | 2019-09-10 | 2019-10-23 | Francis Crick Institute Ltd | Treatment of hr deficient cancer |
WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
AU2021318572A1 (en) * | 2020-07-31 | 2023-02-16 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Indolo heptamyl oxime analog crystal as PARP inhibitor and method for preparing same |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999011644A1 (en) * | 1997-09-03 | 1999-03-11 | Guilford Pharmaceuticals Inc. | Di-n-heterocyclic compounds, methods, and compositions for inhibiting parp activity |
EP1140936B1 (de) * | 1999-01-11 | 2004-03-17 | Agouron Pharmaceuticals, Inc. | Tricyclische inhibitoren von poly(adp-ribose) polymerasen |
ECSP003637A (es) * | 1999-08-31 | 2002-03-25 | Agouron Pharma | Inhibidores triciclicos de poli (adp-ribosa) polimerasas |
-
2000
- 2000-09-15 KR KR1020017006614A patent/KR20010087401A/ko not_active Application Discontinuation
- 2000-09-15 JP JP2001526542A patent/JP2003510328A/ja active Pending
- 2000-09-15 HU HU0104917A patent/HUP0104917A3/hu unknown
- 2000-09-15 CZ CZ20012373A patent/CZ20012373A3/cs unknown
- 2000-09-15 CN CN00802408A patent/CN1374961A/zh active Pending
- 2000-09-15 EP EP00974379A patent/EP1183259A2/de not_active Withdrawn
- 2000-09-15 IL IL14334900A patent/IL143349A0/xx unknown
- 2000-09-15 AU AU12712/01A patent/AU1271201A/en not_active Abandoned
- 2000-09-15 SK SK884-2001A patent/SK8842001A3/sk unknown
- 2000-09-15 CA CA002352194A patent/CA2352194A1/en not_active Abandoned
- 2000-09-15 PL PL00347885A patent/PL347885A1/xx not_active Application Discontinuation
- 2000-09-15 WO PCT/EP2000/009024 patent/WO2001023390A2/de not_active Application Discontinuation
- 2000-09-15 TR TR2001/01499T patent/TR200101499T1/xx unknown
- 2000-09-15 BR BR0007174-9A patent/BR0007174A/pt not_active IP Right Cessation
-
2001
- 2001-05-25 NO NO20012567A patent/NO20012567L/no not_active Application Discontinuation
- 2001-06-26 BG BG105650A patent/BG105650A/xx unknown
-
2003
- 2003-02-18 HK HK03101179.8A patent/HK1048999A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
HK1048999A1 (zh) | 2003-04-25 |
HUP0104917A3 (en) | 2002-12-28 |
CN1374961A (zh) | 2002-10-16 |
SK8842001A3 (en) | 2002-01-07 |
KR20010087401A (ko) | 2001-09-15 |
IL143349A0 (en) | 2002-04-21 |
NO20012567L (no) | 2001-06-25 |
CA2352194A1 (en) | 2001-04-05 |
TR200101499T1 (tr) | 2002-09-23 |
WO2001023390A2 (de) | 2001-04-05 |
WO2001023390A3 (de) | 2001-12-27 |
BG105650A (en) | 2002-02-28 |
JP2003510328A (ja) | 2003-03-18 |
HUP0104917A2 (hu) | 2002-04-29 |
NO20012567D0 (no) | 2001-05-25 |
EP1183259A2 (de) | 2002-03-06 |
PL347885A1 (en) | 2002-04-22 |
AU1271201A (en) | 2001-04-30 |
CZ20012373A3 (cs) | 2002-05-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 3A, 4A, 5A, 6A E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1925 DE 27/11/2007. |