BR0005798A - Processo para preparação fermentativa del-aminoácidos usando bactérias corineforme - Google Patents

Processo para preparação fermentativa del-aminoácidos usando bactérias corineforme

Info

Publication number
BR0005798A
BR0005798A BR0005798-3A BR0005798A BR0005798A BR 0005798 A BR0005798 A BR 0005798A BR 0005798 A BR0005798 A BR 0005798A BR 0005798 A BR0005798 A BR 0005798A
Authority
BR
Brazil
Prior art keywords
bacteria
amino acids
amino acid
glya
fermentative preparation
Prior art date
Application number
BR0005798-3A
Other languages
English (en)
Inventor
Petra Ziegler
Lothar Eggeling
Hermann Sahm
Georg Thierbach
Alter Pfefferle
Original Assignee
Degussa
Forschungszentrum Juelich Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa, Forschungszentrum Juelich Gmbh filed Critical Degussa
Publication of BR0005798A publication Critical patent/BR0005798A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1014—Hydroxymethyl-, formyl-transferases (2.1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Patente de Invenção: "PROCESSO PARA PREPARAçãOFERMENTATIVA DE L-AMINOáCIDOS USANDO BACTéRIASCORINEFORME". A invenção refere-se ao processo parapreparação de L-aminoácidos, nos quais as etapas que se seguemsão realizadas: a) fermentação das bactérias produzindoL-aminoácidos desejados, onde pelo menos o gene glyA éatenuado, especificamente por remoção do promotor natural, b)concentração do produto desejado no meio ou nas células dasbactérias, e c) isolamento do L-aminoácido, e opcionalmente sãoempregadas bactérias nas quais os genes adicionais da passagemde biossíntese do L-aminoácido desejado são adicionalmenteampliadas, ou são empregadas bactérias nas quais as passagensmetabólicas que reduzem a formação do L-aminoácido desejadosão pelo menos parcialmente eliminadas, e seq³ências denucleotídeo da unidade laci-tac5<39>glyA ou lacl-tac-glyA.
BR0005798-3A 1999-12-09 2000-12-08 Processo para preparação fermentativa del-aminoácidos usando bactérias corineforme BR0005798A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19959329A DE19959329A1 (de) 1999-12-09 1999-12-09 Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien

Publications (1)

Publication Number Publication Date
BR0005798A true BR0005798A (pt) 2001-11-20

Family

ID=7931970

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0005798-3A BR0005798A (pt) 1999-12-09 2000-12-08 Processo para preparação fermentativa del-aminoácidos usando bactérias corineforme

Country Status (14)

Country Link
US (1) US6596516B2 (pt)
EP (1) EP1106695A3 (pt)
JP (1) JP2001190296A (pt)
KR (1) KR20010062270A (pt)
CN (1) CN1305009A (pt)
AU (1) AU7209000A (pt)
BR (1) BR0005798A (pt)
CA (1) CA2325593A1 (pt)
DE (1) DE19959329A1 (pt)
HU (1) HUP0004875A2 (pt)
ID (1) ID28603A (pt)
PL (1) PL344388A1 (pt)
SK (1) SK18332000A3 (pt)
ZA (1) ZA200007271B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI9813021B1 (pt) * 1997-10-04 2016-04-05 Degussa processo para a preparação microbiana de aminoácidos de l-lisina, l-treonina, l-homosserina e glutamato, vetor, e célula transformada
EP1247868A3 (de) * 2001-04-03 2002-10-30 Degussa AG Verfahren zur fermentativen Herstellung von D-Pantothensäure und/oder deren Salzen
WO2003029457A1 (fr) * 2001-09-28 2003-04-10 Kyowa Hakko Kogyo Co., Ltd. Procede de production d'acide amine
DE102005047596A1 (de) * 2005-10-05 2007-04-12 Degussa Ag Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien
DE102005049527B4 (de) * 2005-10-17 2013-05-08 Forschungszentrum Jülich GmbH Verfahren zur Herstellung von L-Serin, Gensequenz, Vektoren sowie Mikroorganismus
DE102007005072A1 (de) * 2007-02-01 2008-08-07 Evonik Degussa Gmbh Verfahren zur fermentativen Herstellung von Cadaverin
JP2010110217A (ja) * 2007-02-22 2010-05-20 Ajinomoto Co Inc Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造法
CN104313105B (zh) * 2014-09-29 2017-09-08 呼伦贝尔东北阜丰生物科技有限公司 一种利用苏氨酸发酵液及废母液制备65%苏氨酸的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3682709D1 (de) * 1985-05-13 1992-01-16 Toray Industries Verfahren zur herstellung von l-threonin durch fermentation.
EP0204326B1 (en) * 1985-06-05 1992-03-25 Kyowa Hakko Kogyo Co., Ltd. Process for producing l-threonine and l-isoleucine
EP0338790A3 (en) * 1988-04-20 1989-11-29 Biotechnica International, Inc. Production of homoserine and its derivatives such as threonine derivatives and methionine precursors
JPH08107788A (ja) * 1994-10-11 1996-04-30 Mitsubishi Chem Corp セリンヒドロキシメチルトランスフェラーゼをコードする遺伝子を含むｄｎａ断片

Also Published As

Publication number Publication date
DE19959329A1 (de) 2001-06-13
CA2325593A1 (en) 2001-06-09
EP1106695A2 (de) 2001-06-13
PL344388A1 (en) 2001-06-18
EP1106695A3 (de) 2001-07-04
HU0004875D0 (pt) 2001-02-28
ID28603A (id) 2001-06-14
US6596516B2 (en) 2003-07-22
SK18332000A3 (sk) 2001-09-11
CN1305009A (zh) 2001-07-25
US20020072098A1 (en) 2002-06-13
KR20010062270A (ko) 2001-07-07
ZA200007271B (en) 2001-06-07
JP2001190296A (ja) 2001-07-17
HUP0004875A2 (en) 2002-09-28
AU7209000A (en) 2001-06-14

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]