BG99521A - Preparation of n-substituted oligomers - Google Patents

Preparation of n-substituted oligomers

Info

Publication number
BG99521A
BG99521A BG99521A BG9952195A BG99521A BG 99521 A BG99521 A BG 99521A BG 99521 A BG99521 A BG 99521A BG 9952195 A BG9952195 A BG 9952195A BG 99521 A BG99521 A BG 99521A
Authority
BG
Bulgaria
Prior art keywords
substituted
oligomers
produced
acylation
peptido
Prior art date
Application number
BG99521A
Other languages
Bulgarian (bg)
English (en)
Inventor
Ronald Zuckermann
Janice Kerr
Stephen Kent
Walter Moos
Reyna Simon
Dane Goff
Original Assignee
Chiron Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corporation filed Critical Chiron Corporation
Publication of BG99521A publication Critical patent/BG99521A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C08G69/10Alpha-amino-carboxylic acids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00596Solid-phase processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/0072Organic compounds
BG99521A 1992-09-24 1995-03-23 Preparation of n-substituted oligomers BG99521A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95085392A 1992-09-24 1992-09-24
PCT/US1993/009117 WO1994006451A1 (en) 1992-09-24 1993-09-24 Synthesis of n-substituted oligomers

Publications (1)

Publication Number Publication Date
BG99521A true BG99521A (en) 1996-01-31

Family

ID=25490930

Family Applications (1)

Application Number Title Priority Date Filing Date
BG99521A BG99521A (en) 1992-09-24 1995-03-23 Preparation of n-substituted oligomers

Country Status (17)

Country Link
US (1) US20020115612A1 (de)
EP (2) EP1258492A1 (de)
JP (3) JP3461505B2 (de)
KR (1) KR0168709B1 (de)
AT (1) ATE228532T1 (de)
AU (1) AU679945B2 (de)
BG (1) BG99521A (de)
BR (1) BR9307092A (de)
CA (1) CA2144067A1 (de)
DE (1) DE69332524T2 (de)
FI (1) FI951356A (de)
HK (1) HK1049173A1 (de)
HU (1) HUT72614A (de)
NO (1) NO950682L (de)
NZ (1) NZ256952A (de)
PL (1) PL308204A1 (de)
WO (1) WO1994006451A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5877278A (en) * 1992-09-24 1999-03-02 Chiron Corporation Synthesis of N-substituted oligomers
US5536853A (en) * 1994-04-11 1996-07-16 Chiron Corporation Opiate receptor ligands
US5939268A (en) * 1994-07-26 1999-08-17 The Scripps Research Institute Combinatorial libraries of molecules and methods for producing same
US5481020A (en) * 1994-12-30 1996-01-02 Chiron Corporation Opiate receptor ligands
ATE235504T1 (de) * 1994-12-30 2003-04-15 Chiron Corp Verfahren zur kontrollierten synthese von beliebigen peptidmischungen kodierende polynukleotidmischungen
US5891742A (en) * 1995-01-19 1999-04-06 Chiron Corporation Affinity selection of ligands by mass spectroscopy
US5627210A (en) * 1995-02-06 1997-05-06 Chiron Corporation Branched combinatorial libraries
US5747458A (en) * 1995-06-07 1998-05-05 Chiron Corporation Urokinase receptor ligands
US5958792A (en) * 1995-06-07 1999-09-28 Chiron Corporation Combinatorial libraries of substrate-bound cyclic organic compounds
US6277583B1 (en) 1996-02-07 2001-08-21 Conjuchem, Inc. Affinity labeling libraries and applications thereof
EP0941122B1 (de) * 1996-08-13 2003-10-29 Chiron Corporation Zusammensetzungen zur polynukleotidabgabe
US6045755A (en) * 1997-03-10 2000-04-04 Trega Biosciences,, Inc. Apparatus and method for combinatorial chemistry synthesis
US6033631A (en) * 1997-04-28 2000-03-07 Chiron Corporation Synthesizer with reagent recycling
US6197332B1 (en) 1997-08-13 2001-03-06 Chiron Corporation Lipid-conjugated polyamide compounds and related compositions and methods thereof
AU1519699A (en) 1997-11-07 1999-05-31 Conjuchem, Inc. Affinity markers for human serum albumin
ATE279430T1 (de) 1998-03-05 2004-10-15 Chiron Corp Verfahren zur verbesserung der serum halbwertszeit von biologisch aktiven molekülen
WO2000043547A1 (en) 1999-01-20 2000-07-27 Northwestern University Dna mobility modifier
CA2431219C (en) 2000-12-23 2012-02-07 Chiron Corporation Oligonucleotide transfection screening method
US7664553B2 (en) * 2005-04-27 2010-02-16 Cardiac Pacemakers, Inc. System and method for enabling communications with implantable medical devices
DK1931695T3 (da) * 2005-09-09 2013-07-01 Novartis Ag Prionspecifikke peptoidreagenser
EP1987009A1 (de) * 2006-01-30 2008-11-05 Euro-Celtique S.A. Cycloharnstoffverbindung als calciumkanalblocker
DE102006039615A1 (de) * 2006-08-24 2008-03-13 Leibniz-Institut Für Pflanzenbiochemie Esterelongationsverfahren zum sequenzgesteuerten Aufbau alternierender Peptid-Peptoid-Polymere (Peptid-Peptoid-Polymere)
US7888462B2 (en) 2007-01-22 2011-02-15 Acologix, Inc. Peptide composition and a method of promoting cartilage formation
JP4997038B2 (ja) * 2007-07-27 2012-08-08 株式会社ブリヂストン 更生タイヤ用トレッド及び更生タイヤ
WO2009105167A2 (en) 2008-02-08 2009-08-27 Northwestern University Selective poly-n-substituted glycine antibiotics
WO2011115687A2 (en) * 2010-03-19 2011-09-22 Northwestern University Alkylated sp-b peptoid compounds and related lung surfactant compositions
US9764953B2 (en) 2013-03-20 2017-09-19 The Regents Of The University Of California Peptoids useful for the mineralization of apatite
MX2018004518A (es) 2015-10-14 2018-09-18 X Therma Inc Composiciones y metodos para reducir la formacion de cristales de hielo.
JP2019518017A (ja) 2016-02-09 2019-06-27 アレクサンダー・クランツ トレースレス親和性標識を使用したタンパク質の部位選択的官能化
RS63143B1 (sr) 2016-06-01 2022-05-31 Athira Pharma Inc Jedinjenja
WO2019051494A1 (en) 2017-09-11 2019-03-14 Protagonist Therapeutics, Inc. OPIOID AGONIST PEPTIDES AND USES THEREOF
EP3703676A4 (de) 2017-11-04 2021-12-15 Advanced Proteome Therapeutics, Inc. Zusammensetzung und verfahren zur modifizierung von polypeptiden
KR20240007491A (ko) 2022-07-08 2024-01-16 문정현 수평유지하는 유모차

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1037474A (en) * 1964-04-21 1966-07-27 British Nylon Spinners Ltd N-substituted polyamides and filaments therefrom
US3634364A (en) * 1969-09-26 1972-01-11 Grace W R & Co Polyminodiacetic acid and polysarcosine homopolymers
DE2447305C3 (de) * 1973-10-05 1979-09-13 Miyoshi Yushi K.K., Tokio Verfahren zur Herstellung chelatbildender Polymerisate
ATE124999T1 (de) * 1985-03-15 1995-07-15 Antivirals Inc Immunotestmittel für polynukleotid und verfahren.
US5066716A (en) * 1988-12-13 1991-11-19 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Synthesis of chloroacetyl and bromoacetyl modified peptides for the preparation of synthetic peptide polymers, conjugated peptides, and cyclic peptides
IE66205B1 (en) * 1990-06-14 1995-12-13 Paul A Bartlett Polypeptide analogs

Also Published As

Publication number Publication date
AU679945B2 (en) 1997-07-17
NO950682L (no) 1995-04-18
HK1049173A1 (zh) 2003-05-02
EP1258492A1 (de) 2002-11-20
PL308204A1 (en) 1995-07-24
JP3596752B2 (ja) 2004-12-02
AU5292093A (en) 1994-04-12
WO1994006451A1 (en) 1994-03-31
FI951356A0 (fi) 1995-03-22
ATE228532T1 (de) 2002-12-15
KR950703349A (ko) 1995-09-20
NZ256952A (en) 1997-07-27
FI951356A (fi) 1995-04-26
JP2003012622A (ja) 2003-01-15
EP0671928A1 (de) 1995-09-20
KR0168709B1 (ko) 1999-01-15
DE69332524D1 (de) 2003-01-16
US20020115612A1 (en) 2002-08-22
JP3461505B2 (ja) 2003-10-27
JP2000239242A (ja) 2000-09-05
NO950682D0 (no) 1995-02-23
JPH08501565A (ja) 1996-02-20
HU9500855D0 (en) 1995-05-29
HUT72614A (en) 1996-05-28
BR9307092A (pt) 1999-03-30
EP0671928A4 (de) 1997-04-23
DE69332524T2 (de) 2003-04-24
CA2144067A1 (en) 1994-03-31
EP0671928B1 (de) 2002-11-27

Similar Documents

Publication Publication Date Title
BG99521A (en) Preparation of n-substituted oligomers
CA2179530A1 (en) Cyclic polyamines
GR3030061T3 (en) Method of preparing a radioactive rhenium complex solution.
EP0722458A4 (de) Peralkylierte oligopeptidmischungen
BG101482A (en) Substituted 4-biarylbutane or 5-biarylpentane acids and their derivatives as inhibitors of matrix metalloprotease
ES2008828A6 (es) Procedimiento para la obtencion de poliamidas transparentes termoplasticas.
ATE42564T1 (de) Verfahren zur herstellung von polyamidpulvern.
GB1536870A (en) Process for removal of polyphenols in vegetable beverages
ATE28078T1 (de) Peptide derivate, inhibitor von saeureproteasen, verfahren zu deren herstellung.
DE3069862D1 (en) Process for preparing polyamides having a modified dye affinity and the products thus obtained
EP0273243A3 (de) Amino- und Amidgruppen enthaltende Polyesterpolyole und daraus hergestellte Poly(harnstoff)urethane
GR900300062T1 (en) Immunostimulating peptides, a process for their preparation and pharmaceutical commpositions containing them
IE42978L (en) Azabicyclo compounds
JPS5668610A (en) Antitumorigenic agent containing napthalenesulfonamide as effective component
ATE380798T1 (de) Neue aminoalkoholderivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel und reagenzien
ATE172185T1 (de) Verfahren zur gleichzeitigen herstellung von dicarbonsäuren und diaminen durch spaltung von polyamiden in ihre monomeren bestandteile
ATE32342T1 (de) N-nitroso-n-(beta-chloro-aethyl)-carboroylpeptide.
GB1161177A (en) Novel Polyamide and process for its preparation
RU92008969A (ru) 1-аминоалкилпроизводные 5(6)-амино-2-(n-аминофенил)бензимидозола в качестве мономеров для высокопрочных термостойких анионообменных полимерных материалов
TW327631B (en) Process for the preparation of N-(ortho-alkylphenyl)-imides
EP0277596A3 (de) Amino-beta-alkylstyrole verwendet zur Herstellung von Polyurethan/Harnstoffsystemen und Polymeren
DE69620162D1 (de) Reduktives verfahren zur herstellung von ethylendiamindibernsteinsäure
GB1472468A (en) Melt-condensed polyamide interpolymers
TH23453A (th) กรดดีโพลิเมอร์ไรซ์โพลิเอมีด
IL100093A (en) Thrombin-binding substance and process for preparing the same