ATE235504T1 - Verfahren zur kontrollierten synthese von beliebigen peptidmischungen kodierende polynukleotidmischungen - Google Patents
Verfahren zur kontrollierten synthese von beliebigen peptidmischungen kodierende polynukleotidmischungenInfo
- Publication number
- ATE235504T1 ATE235504T1 AT95943853T AT95943853T ATE235504T1 AT E235504 T1 ATE235504 T1 AT E235504T1 AT 95943853 T AT95943853 T AT 95943853T AT 95943853 T AT95943853 T AT 95943853T AT E235504 T1 ATE235504 T1 AT E235504T1
- Authority
- AT
- Austria
- Prior art keywords
- peptide
- mixtures
- polynucleotides
- mixture
- proportions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36666294A | 1994-12-30 | 1994-12-30 | |
PCT/US1995/016443 WO1996020947A1 (en) | 1994-12-30 | 1995-12-15 | Method for the controlled synthesis of polynucleotide mixtures which encode desired mixtures of peptides |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE235504T1 true ATE235504T1 (de) | 2003-04-15 |
Family
ID=23443980
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95943853T ATE235504T1 (de) | 1994-12-30 | 1995-12-15 | Verfahren zur kontrollierten synthese von beliebigen peptidmischungen kodierende polynukleotidmischungen |
Country Status (8)
Country | Link |
---|---|
US (1) | US5789577A (de) |
EP (1) | EP0800526B1 (de) |
JP (1) | JPH10511554A (de) |
AT (1) | ATE235504T1 (de) |
AU (1) | AU4522196A (de) |
CA (1) | CA2208693A1 (de) |
DE (1) | DE69530119T2 (de) |
WO (1) | WO1996020947A1 (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6438561B1 (en) * | 1998-11-19 | 2002-08-20 | Navigation Technologies Corp. | Method and system for using real-time traffic broadcasts with navigation systems |
US20030054390A1 (en) * | 1999-01-19 | 2003-03-20 | Maxygen, Inc. | Oligonucleotide mediated nucleic acid recombination |
US6436675B1 (en) | 1999-09-28 | 2002-08-20 | Maxygen, Inc. | Use of codon-varied oligonucleotide synthesis for synthetic shuffling |
US6376246B1 (en) | 1999-02-05 | 2002-04-23 | Maxygen, Inc. | Oligonucleotide mediated nucleic acid recombination |
US6368861B1 (en) | 1999-01-19 | 2002-04-09 | Maxygen, Inc. | Oligonucleotide mediated nucleic acid recombination |
US6917882B2 (en) * | 1999-01-19 | 2005-07-12 | Maxygen, Inc. | Methods for making character strings, polynucleotides and polypeptides having desired characteristics |
US7702464B1 (en) | 2001-08-21 | 2010-04-20 | Maxygen, Inc. | Method and apparatus for codon determining |
EP1108783A3 (de) | 1999-01-19 | 2001-09-05 | Maxygen, Inc. | Oligonukletiden-gesteuerte Nukleinsäurerekombination |
US8457903B1 (en) | 1999-01-19 | 2013-06-04 | Codexis Mayflower Holdings, Llc | Method and/or apparatus for determining codons |
US6961664B2 (en) | 1999-01-19 | 2005-11-01 | Maxygen | Methods of populating data structures for use in evolutionary simulations |
US20070065838A1 (en) * | 1999-01-19 | 2007-03-22 | Maxygen, Inc. | Oligonucleotide mediated nucleic acid recombination |
US7873477B1 (en) | 2001-08-21 | 2011-01-18 | Codexis Mayflower Holdings, Llc | Method and system using systematically varied data libraries |
US7024312B1 (en) | 1999-01-19 | 2006-04-04 | Maxygen, Inc. | Methods for making character strings, polynucleotides and polypeptides having desired characteristics |
US7604996B1 (en) * | 1999-08-18 | 2009-10-20 | Illumina, Inc. | Compositions and methods for preparing oligonucleotide solutions |
US7430477B2 (en) | 1999-10-12 | 2008-09-30 | Maxygen, Inc. | Methods of populating data structures for use in evolutionary simulations |
US20050095648A1 (en) * | 2003-10-30 | 2005-05-05 | Mario Geysen | Method for designing linear epitopes and algorithm therefor and polypeptide epitopes |
US20100113287A1 (en) * | 2004-09-10 | 2010-05-06 | Rosetta Inpharmatics Llc | Methods for assessing the representation of nucleic acid molecules in a nucleic acid library |
US7642539B2 (en) * | 2005-12-13 | 2010-01-05 | Macronix International Co., Ltd. | Thin film fuse phase change cell with thermal isolation pad and manufacturing method |
EP3814494B1 (de) | 2018-06-29 | 2023-11-01 | Thermo Fisher Scientific GENEART GmbH | Hochdurchsatzanordnung von nukleinsäuremolekülen |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5010175A (en) * | 1988-05-02 | 1991-04-23 | The Regents Of The University Of California | General method for producing and selecting peptides with specific properties |
US5223409A (en) * | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
JPH04504416A (ja) * | 1989-02-17 | 1992-08-06 | コセルコ・ミモトープス・ピィ・ティ・ワイ.エル・ティ・ディ. | ペプチドの使用方法と合成方法 |
EP0494955B1 (de) * | 1989-10-05 | 1998-07-15 | Optein, Inc. | Zellfreie synthese und isolierung von genen und polypeptiden |
US5723286A (en) * | 1990-06-20 | 1998-03-03 | Affymax Technologies N.V. | Peptide library and screening systems |
WO1992002536A1 (en) * | 1990-08-02 | 1992-02-20 | The Regents Of The University Of Colorado | Systematic polypeptide evolution by reverse translation |
US5264563A (en) * | 1990-08-24 | 1993-11-23 | Ixsys Inc. | Process for synthesizing oligonucleotides with random codons |
IL99553A0 (en) * | 1990-09-28 | 1992-08-18 | Ixsys Inc | Compositions containing oligonucleotides linked to expression elements,a kit for the preparation of vectors useful for the expression of a diverse population of random peptides and methods utilizing the same |
EP0638089B2 (de) * | 1992-04-15 | 2008-03-05 | The Johns Hopkins University | Synthese von verschiedenen und nützlichen oligonukleotidsammlungen |
PL308204A1 (en) * | 1992-09-24 | 1995-07-24 | Chiron Corp | Synthesis of n-substituted oligomers |
-
1995
- 1995-12-15 EP EP95943853A patent/EP0800526B1/de not_active Expired - Lifetime
- 1995-12-15 JP JP8521037A patent/JPH10511554A/ja active Pending
- 1995-12-15 DE DE69530119T patent/DE69530119T2/de not_active Expired - Fee Related
- 1995-12-15 CA CA002208693A patent/CA2208693A1/en not_active Abandoned
- 1995-12-15 AT AT95943853T patent/ATE235504T1/de not_active IP Right Cessation
- 1995-12-15 WO PCT/US1995/016443 patent/WO1996020947A1/en active IP Right Grant
- 1995-12-15 AU AU45221/96A patent/AU4522196A/en not_active Abandoned
-
1996
- 1996-12-06 US US08/760,919 patent/US5789577A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPH10511554A (ja) | 1998-11-10 |
EP0800526A1 (de) | 1997-10-15 |
AU4522196A (en) | 1996-07-24 |
DE69530119T2 (de) | 2003-09-25 |
CA2208693A1 (en) | 1996-07-11 |
US5789577A (en) | 1998-08-04 |
WO1996020947A1 (en) | 1996-07-11 |
EP0800526B1 (de) | 2003-03-26 |
DE69530119D1 (de) | 2003-05-08 |
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Legal Events
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |