FI951356A0 - N-substituoitujen oligomeerien synteesi - Google Patents

N-substituoitujen oligomeerien synteesi

Info

Publication number
FI951356A0
FI951356A0 FI951356A FI951356A FI951356A0 FI 951356 A0 FI951356 A0 FI 951356A0 FI 951356 A FI951356 A FI 951356A FI 951356 A FI951356 A FI 951356A FI 951356 A0 FI951356 A0 FI 951356A0
Authority
FI
Finland
Prior art keywords
oligomers
substituted
poly
nsgs
synthesis
Prior art date
Application number
FI951356A
Other languages
English (en)
Swedish (sv)
Other versions
FI951356A (fi
Inventor
Ronald N Zuckermann
Janice M Kerr
Stephen Brian Henry Kent
Walter H Moos
Reyna J Simon
Dane A Goff
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of FI951356A0 publication Critical patent/FI951356A0/fi
Publication of FI951356A publication Critical patent/FI951356A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C08G69/10—Alpha-amino-carboxylic acids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Polyamides (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FI951356A 1992-09-24 1995-03-22 N-substituoitujen oligomeerien synteesi FI951356A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95085392A 1992-09-24 1992-09-24
PCT/US1993/009117 WO1994006451A1 (en) 1992-09-24 1993-09-24 Synthesis of n-substituted oligomers

Publications (2)

Publication Number Publication Date
FI951356A0 true FI951356A0 (fi) 1995-03-22
FI951356A FI951356A (fi) 1995-04-26

Family

ID=25490930

Family Applications (1)

Application Number Title Priority Date Filing Date
FI951356A FI951356A (fi) 1992-09-24 1995-03-22 N-substituoitujen oligomeerien synteesi

Country Status (17)

Country Link
US (1) US20020115612A1 (fi)
EP (2) EP1258492A1 (fi)
JP (3) JP3461505B2 (fi)
KR (1) KR0168709B1 (fi)
AT (1) ATE228532T1 (fi)
AU (1) AU679945B2 (fi)
BG (1) BG99521A (fi)
BR (1) BR9307092A (fi)
CA (1) CA2144067A1 (fi)
DE (1) DE69332524T2 (fi)
FI (1) FI951356A (fi)
HK (1) HK1049173A1 (fi)
HU (1) HUT72614A (fi)
NO (1) NO950682L (fi)
NZ (1) NZ256952A (fi)
PL (1) PL308204A1 (fi)
WO (1) WO1994006451A1 (fi)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5877278A (en) * 1992-09-24 1999-03-02 Chiron Corporation Synthesis of N-substituted oligomers
US5536853A (en) * 1994-04-11 1996-07-16 Chiron Corporation Opiate receptor ligands
US5939268A (en) * 1994-07-26 1999-08-17 The Scripps Research Institute Combinatorial libraries of molecules and methods for producing same
AU4522196A (en) * 1994-12-30 1996-07-24 Chiron Corporation Method for the controlled synthesis of polynucleotide mixtures which encode desired mixtures of peptides
US5481020A (en) * 1994-12-30 1996-01-02 Chiron Corporation Opiate receptor ligands
US5891742A (en) * 1995-01-19 1999-04-06 Chiron Corporation Affinity selection of ligands by mass spectroscopy
US5627210A (en) * 1995-02-06 1997-05-06 Chiron Corporation Branched combinatorial libraries
US5747458A (en) * 1995-06-07 1998-05-05 Chiron Corporation Urokinase receptor ligands
US5958792A (en) * 1995-06-07 1999-09-28 Chiron Corporation Combinatorial libraries of substrate-bound cyclic organic compounds
US6277583B1 (en) 1996-02-07 2001-08-21 Conjuchem, Inc. Affinity labeling libraries and applications thereof
DE69725878T2 (de) * 1996-08-13 2004-07-29 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Zusammensetzungen zur polynukleotidabgabe
US6045755A (en) * 1997-03-10 2000-04-04 Trega Biosciences,, Inc. Apparatus and method for combinatorial chemistry synthesis
ATE437887T1 (de) * 1997-04-28 2009-08-15 Novartis Vaccines & Diagnostic Vorrichtung zur herstellung von oligomeren, insbesondere peptoiden, mit rückführung der reagenzien
US6197332B1 (en) 1997-08-13 2001-03-06 Chiron Corporation Lipid-conjugated polyamide compounds and related compositions and methods thereof
EP1056474B1 (en) 1997-11-07 2002-06-12 ConjuChem, Inc. Affinity markers for human serum albumin
ATE279430T1 (de) 1998-03-05 2004-10-15 Chiron Corp Verfahren zur verbesserung der serum halbwertszeit von biologisch aktiven molekülen
WO2000043547A1 (en) 1999-01-20 2000-07-27 Northwestern University Dna mobility modifier
ATE387507T1 (de) 2000-12-23 2008-03-15 Novartis Vaccines & Diagnostic Screeningverfahren für die oligonukleotidtransfektion
US7664553B2 (en) * 2005-04-27 2010-02-16 Cardiac Pacemakers, Inc. System and method for enabling communications with implantable medical devices
KR20080048527A (ko) * 2005-09-09 2008-06-02 노파르티스 아게 프리온-특이적 펩토이드 시약
JP2009525269A (ja) * 2006-01-30 2009-07-09 ユーロ−セルティーク エス．エイ． カルシウムチャネルブロッカーとしての環状尿素化合物
DE102006039615A1 (de) * 2006-08-24 2008-03-13 Leibniz-Institut Für Pflanzenbiochemie Esterelongationsverfahren zum sequenzgesteuerten Aufbau alternierender Peptid-Peptoid-Polymere (Peptid-Peptoid-Polymere)
ES2542509T3 (es) 2007-01-22 2015-08-06 Orthotrophix, Inc. Una composición peptídica y un método de estimulación de la formación de cartílago
JP4997038B2 (ja) * 2007-07-27 2012-08-08 株式会社ブリヂストン 更生タイヤ用トレッド及び更生タイヤ
WO2009105167A2 (en) * 2008-02-08 2009-08-27 Northwestern University Selective poly-n-substituted glycine antibiotics
WO2011115687A2 (en) * 2010-03-19 2011-09-22 Northwestern University Alkylated sp-b peptoid compounds and related lung surfactant compositions
US9764953B2 (en) 2013-03-20 2017-09-19 The Regents Of The University Of California Peptoids useful for the mineralization of apatite
CN108347916B (zh) 2015-10-14 2022-02-08 先时迈纳米生物科技股份有限公司 一种减少冰晶形成的组合物及其方法
JP2019518017A (ja) 2016-02-09 2019-06-27 アレクサンダー・クランツ トレースレス親和性標識を使用したタンパク質の部位選択的官能化
CA3026074A1 (en) 2016-06-01 2017-12-07 M3 Biotechnology, Inc. N-hexanoic-l-tyrosine-l-isoleucine-(6)-aminohexanoic amide compounds and their use to treat neurodegenerative diseases
EP3681900A4 (en) 2017-09-11 2021-09-08 Protagonist Therapeutics, Inc. OPIOID AGONIST PEPTIDES AND THEIR USES
JP2021502418A (ja) 2017-11-04 2021-01-28 アドバンスト・プロテオーム・セラピューティクス・インコーポレイテッド ポリペプチドを修飾するための組成物及び方法
KR20240007491A (ko) 2022-07-08 2024-01-16 문정현 수평유지하는 유모차

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1037474A (en) * 1964-04-21 1966-07-27 British Nylon Spinners Ltd N-substituted polyamides and filaments therefrom
US3634364A (en) * 1969-09-26 1972-01-11 Grace W R & Co Polyminodiacetic acid and polysarcosine homopolymers
DE2447305C3 (de) * 1973-10-05 1979-09-13 Miyoshi Yushi K.K., Tokio Verfahren zur Herstellung chelatbildender Polymerisate
EP0639582B1 (en) * 1985-03-15 1998-09-16 Antivirals Inc. Polynucleotide assay reagent and method
US5066716A (en) * 1988-12-13 1991-11-19 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Synthesis of chloroacetyl and bromoacetyl modified peptides for the preparation of synthetic peptide polymers, conjugated peptides, and cyclic peptides
IE66205B1 (en) * 1990-06-14 1995-12-13 Paul A Bartlett Polypeptide analogs

Also Published As

Publication number Publication date
US20020115612A1 (en) 2002-08-22
AU679945B2 (en) 1997-07-17
NZ256952A (en) 1997-07-27
HU9500855D0 (en) 1995-05-29
HUT72614A (en) 1996-05-28
CA2144067A1 (en) 1994-03-31
ATE228532T1 (de) 2002-12-15
NO950682L (no) 1995-04-18
HK1049173A1 (zh) 2003-05-02
BG99521A (en) 1996-01-31
EP0671928A1 (en) 1995-09-20
JP2000239242A (ja) 2000-09-05
EP0671928A4 (en) 1997-04-23
JP3596752B2 (ja) 2004-12-02
JP2003012622A (ja) 2003-01-15
KR0168709B1 (ko) 1999-01-15
AU5292093A (en) 1994-04-12
DE69332524D1 (de) 2003-01-16
DE69332524T2 (de) 2003-04-24
PL308204A1 (en) 1995-07-24
EP0671928B1 (en) 2002-11-27
NO950682D0 (no) 1995-02-23
KR950703349A (ko) 1995-09-20
BR9307092A (pt) 1999-03-30
JPH08501565A (ja) 1996-02-20
WO1994006451A1 (en) 1994-03-31
JP3461505B2 (ja) 2003-10-27
FI951356A (fi) 1995-04-26
EP1258492A1 (en) 2002-11-20

Similar Documents

Publication Publication Date Title
FI951356A0 (fi) N-substituoitujen oligomeerien synteesi
DE69626621D1 (de) Synthese von n-substituierten oligomeren
DE69130831D1 (de) Synthese äquimolarer mischungen vielzähliger oligomere, speziell oligopeptidmischungen
MY116539A (en) New amino acid derivatives
DK0607054T3 (da) Nyt kemokin produceret af hematopoetiske celler og DNA kodende for kemokines
DE69432147D1 (de) Topologisch getrennte kodierende festphasen-bibliotheken
DE69803913D1 (de) Fluorierung von 1,1,3,3,-Tetrachloro-2-propen in der Gasphase
ES2114633T3 (es) Preparacion y escrutinio de bibliotecas de peptidos muy diversificados en cuanto a su actividad de fijacion.
SE9602263D0 (sv) New amino acid derivatives
DE69416804D1 (de) Entfernung von Verunreinigungen aus Synthesegas
EA200000320A1 (ru) Изохинолины в качестве ингибиторов урокиназы
ATE402212T1 (de) Verfahren zur herstellung von polyisocyanaten
CA2312431A1 (en) New compounds
DK0906272T3 (da) Peptider
MXPA04004802A (es) Derivados del 1,2,4-triazol que contienen un grupo sulfamato como inhibidores de aromatasa.
DE69111327D1 (de) Block von Mikroverbindungsstiften und Verfahren zu dessen Herstellung.
ATE197150T1 (de) Verfahren zur herstellung von dihydroxypyrimidin- derivaten
CA2424558A1 (en) Pitch cycle search range setting apparatus and pitch cycle search apparatus
EP0369743A3 (en) Heterocyclic amides
DE69104816D1 (de) Verfahren zur Herstellung von Ammoniak-Synthesegas.
WO2003014094A3 (de) Heterocyclylarylsulfonamide
DE59006414D1 (de) Verfahren für die Festphasenpolymerisation von Acrylnitril aus der Gasphase.
WO2005040111A3 (en) Combinatorial library of 3-aryl-1h-indole-2-carboxylic acids
WO1999065855A3 (de) Kombinatorische bibliotheken geminal substituierter amine
DE60235497D1 (de) Synthese von 2-cyanziridin-1-carbonsäureamid

Legal Events

Date Code Title Description
FD Application lapsed