BG97200A - Заместени бензимидазоли,метод за получаването им и тяхното фармацевтично приложение - Google Patents
Заместени бензимидазоли,метод за получаването им и тяхното фармацевтично приложение Download PDFInfo
- Publication number
- BG97200A BG97200A BG097200A BG9720092A BG97200A BG 97200 A BG97200 A BG 97200A BG 097200 A BG097200 A BG 097200A BG 9720092 A BG9720092 A BG 9720092A BG 97200 A BG97200 A BG 97200A
- Authority
- BG
- Bulgaria
- Prior art keywords
- preparation
- pharmaceutical application
- substituted benzimidazoles
- benzimidazoles
- substituted
- Prior art date
Links
- 150000001556 benzimidazoles Chemical class 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9002206A SE9002206D0 (sv) | 1990-06-20 | 1990-06-20 | New compounds |
| PCT/SE1991/000415 WO1991019711A1 (en) | 1990-06-20 | 1991-06-11 | Substituted benzimidazoles, process for their preparation and their pharmaceutical use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG97200A true BG97200A (bg) | 1993-12-24 |
Family
ID=20379831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG097200A BG97200A (bg) | 1990-06-20 | 1992-12-18 | Заместени бензимидазоли,метод за получаването им и тяхното фармацевтично приложение |
Country Status (27)
| Country | Link |
|---|---|
| EP (1) | EP0535081A1 (cs) |
| JP (1) | JPH05507713A (cs) |
| CN (1) | CN1058212A (cs) |
| AP (1) | AP215A (cs) |
| AU (1) | AU649453B2 (cs) |
| BG (1) | BG97200A (cs) |
| CA (1) | CA2083714A1 (cs) |
| CZ (1) | CZ279772B6 (cs) |
| FI (1) | FI925766A7 (cs) |
| HU (1) | HUT62881A (cs) |
| IE (1) | IE912025A1 (cs) |
| IL (1) | IL98470A0 (cs) |
| IS (1) | IS3721A7 (cs) |
| LT (2) | LT3977B (cs) |
| LV (1) | LV10953A (cs) |
| MA (1) | MA22199A1 (cs) |
| NO (1) | NO924775L (cs) |
| NZ (1) | NZ238546A (cs) |
| OA (1) | OA09682A (cs) |
| PT (1) | PT98035A (cs) |
| RO (1) | RO110493B1 (cs) |
| SE (1) | SE9002206D0 (cs) |
| TN (1) | TNSN91049A1 (cs) |
| TW (1) | TW216418B (cs) |
| WO (1) | WO1991019711A1 (cs) |
| YU (1) | YU104191A (cs) |
| ZA (2) | ZA914297B (cs) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9002043D0 (sv) * | 1990-06-07 | 1990-06-07 | Astra Ab | Improved method for synthesis |
| SE9103776D0 (sv) * | 1991-12-19 | 1991-12-19 | Astra Ab | New compounds |
| IS4232A (is) * | 1993-12-06 | 1995-06-07 | Astra Aktiebolag | Súbstitúerað bensimidasól, aðferðir við framleiðslu þess og lyfjafræðileg notkun |
| SE504459C2 (sv) * | 1994-07-15 | 1997-02-17 | Astra Ab | Förfarande för framställning av substituerade sulfoxider |
| SE9500422D0 (sv) * | 1995-02-06 | 1995-02-06 | Astra Ab | New oral pharmaceutical dosage forms |
| SE9500478D0 (sv) * | 1995-02-09 | 1995-02-09 | Astra Ab | New pharmaceutical formulation and process |
| SE9600070D0 (sv) | 1996-01-08 | 1996-01-08 | Astra Ab | New oral pharmaceutical dosage forms |
| PT1257269E (pt) | 2000-02-24 | 2005-03-31 | Kopran Res Lab Ltd | Derivados do benzimidazole anti-ulcera estavel em relacao ao acido de administracao oral |
| SE0101379D0 (sv) | 2001-04-18 | 2001-04-18 | Diabact Ab | Komposition som hämmar utsöndring av magsyra |
| US8206741B2 (en) | 2001-06-01 | 2012-06-26 | Pozen Inc. | Pharmaceutical compositions for the coordinated delivery of NSAIDs |
| ATE419840T1 (de) | 2002-04-09 | 2009-01-15 | Flamel Tech Sa | Orale wässrige suspension, mikrokapseln enthaltend, zur kontrollierten freisetzung von wirkstoffen |
| SE0203065D0 (sv) | 2002-10-16 | 2002-10-16 | Diabact Ab | Gastric acid secretion inhibiting composition |
| AU2004314693B2 (en) | 2003-09-26 | 2011-04-07 | Alza Corporation | Drug coating providing high drug loading and methods for providing the same |
| TW200606163A (en) | 2004-04-22 | 2006-02-16 | Eisai Co Ltd | Imidazopyridine compound |
| US8541026B2 (en) | 2004-09-24 | 2013-09-24 | Abbvie Inc. | Sustained release formulations of opioid and nonopioid analgesics |
| US20070015782A1 (en) | 2005-04-15 | 2007-01-18 | Eisai Co., Ltd. | Benzimidazole compound |
| US9040564B2 (en) | 2005-04-28 | 2015-05-26 | Eisai R&D Management Co., Ltd. | Stabilized composition |
| US7803817B2 (en) | 2005-05-11 | 2010-09-28 | Vecta, Ltd. | Composition and methods for inhibiting gastric acid secretion |
| US7981908B2 (en) | 2005-05-11 | 2011-07-19 | Vecta, Ltd. | Compositions and methods for inhibiting gastric acid secretion |
| WO2007122686A1 (ja) * | 2006-04-14 | 2007-11-01 | Eisai R & D Management Co., Ltd. | ベンズイミダゾール化合物 |
| US9233092B2 (en) | 2006-07-25 | 2016-01-12 | Vecta, Ltd. | Compositions and methods for inhibiting gastric acid secretion using derivatives of small dicarboxylic acids in combination with PPI |
| EP2065379A4 (en) * | 2006-10-13 | 2011-01-19 | Eisai R&D Man Co Ltd | BENZIMIDAZOLE HAVING INHIBITORY ACTIVITY OF GASTRIC ACID SECRETION |
| KR20110079641A (ko) | 2008-09-09 | 2011-07-07 | 아스트라제네카 아베 | 제약 조성물을 이를 필요로 하는 환자에게 전달하는 방법 |
| KR20120030106A (ko) | 2009-06-25 | 2012-03-27 | 아스트라제네카 아베 | Ｎｓａｉｄ-연관된 궤양의 발생 위험이 있는 환자의 치료 방법 |
| WO2011080500A2 (en) | 2009-12-29 | 2011-07-07 | Orexo Ab | New pharmaceutical dosage form for the treatment of gastric acid-related disorders |
| WO2011080501A2 (en) | 2009-12-29 | 2011-07-07 | Orexo Ab | New pharmaceutical dosage form for the treatment of gastric acid-related disorders |
| WO2011080502A2 (en) | 2009-12-29 | 2011-07-07 | Orexo Ab | New pharmaceutical dosage form for the treatment of gastric acid-related disorders |
| EP2601947A1 (en) | 2011-12-05 | 2013-06-12 | Abo Bakr Mohammed Ali Al-Mehdar | Fixed-dose combination for treatment of helicobacter pylori associated diseases |
| CN104519888A (zh) | 2011-12-28 | 2015-04-15 | 波曾公司 | 用于递送奥美拉唑和乙酰水杨酸的改良组合物和方法 |
| IL265108B2 (en) | 2016-09-14 | 2024-03-01 | Yufeng Jane Tseng | Novel substituted benzimidazole derivatives as d-amino acid oxidase (daao) inhibitors |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE418966B (sv) | 1974-02-18 | 1981-07-06 | Haessle Ab | Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan |
| SE416649B (sv) | 1974-05-16 | 1981-01-26 | Haessle Ab | Forfarande for framstellning av foreningar som paverkar magsyrasekretionen |
| IN148930B (cs) | 1977-09-19 | 1981-07-25 | Hoffmann La Roche | |
| SE7804231L (sv) | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
| US4359465A (en) | 1980-07-28 | 1982-11-16 | The Upjohn Company | Methods for treating gastrointestinal inflammation |
| CH644116A5 (de) | 1980-08-21 | 1984-07-13 | Hoffmann La Roche | Imidazolderivate. |
| SE8300736D0 (sv) | 1983-02-11 | 1983-02-11 | Haessle Ab | Novel pharmacologically active compounds |
| SE8301182D0 (sv) | 1983-03-04 | 1983-03-04 | Haessle Ab | Novel compounds |
| IL75400A (en) * | 1984-06-16 | 1988-10-31 | Byk Gulden Lomberg Chem Fab | Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same |
| AU568441B2 (en) * | 1984-09-24 | 1987-12-24 | Upjohn Company, The | 2-(pyridylalkenesulfinyl) benzimidazole derivatives |
| IL76839A (en) * | 1984-10-31 | 1988-08-31 | Byk Gulden Lomberg Chem Fab | Picoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same |
| US4738975A (en) | 1985-07-02 | 1988-04-19 | Takeda Chemical Industries, Ltd. | Pyridine derivatives, and use as anti-ulcer agents |
| SE8505112D0 (sv) * | 1985-10-29 | 1985-10-29 | Haessle Ab | Novel pharmacological compounds |
| NZ234564A (en) | 1986-11-21 | 1991-04-26 | Haessle Ab | 1-substituted benzimidazoles and pharmaceutical compositions |
| DE3722810A1 (de) * | 1987-07-10 | 1989-01-19 | Hoechst Ag | Substituierte benzimidazole, verfahren zu deren herstellung, diese enthaltende pharmazeutische zubereitungen und deren verwendung |
| HU886738D0 (en) * | 1987-10-30 | 1990-02-28 | Haessle Ab | Process for the preparation of pharmaceutical compositions against osteoporosis containing 2-pyridinyl-methyl-(sulfinyl or thio)-benzimidazoles |
| ZA889194B (en) * | 1987-12-11 | 1989-08-30 | Byk Gulden Lomberg Chemisch Fa | Novel benzimidazole derivatives |
| WO1989011479A1 (en) * | 1988-05-25 | 1989-11-30 | Byk Gulden Lomberg Chemische Fabrik Gmbh | New fluoralkoxy compounds |
-
1990
- 1990-06-20 SE SE9002206A patent/SE9002206D0/xx unknown
-
1991
- 1991-06-05 ZA ZA914297A patent/ZA914297B/xx unknown
- 1991-06-05 ZA ZA914296A patent/ZA914296B/xx unknown
- 1991-06-11 JP JP91511435A patent/JPH05507713A/ja active Pending
- 1991-06-11 AU AU80097/91A patent/AU649453B2/en not_active Ceased
- 1991-06-11 HU HU924033A patent/HUT62881A/hu unknown
- 1991-06-11 EP EP91911659A patent/EP0535081A1/en not_active Withdrawn
- 1991-06-11 RO RO92-01581A patent/RO110493B1/ro unknown
- 1991-06-11 CA CA002083714A patent/CA2083714A1/en not_active Abandoned
- 1991-06-11 WO PCT/SE1991/000415 patent/WO1991019711A1/en not_active Application Discontinuation
- 1991-06-12 YU YU104191A patent/YU104191A/sh unknown
- 1991-06-12 TW TW080104582A patent/TW216418B/zh active
- 1991-06-12 IL IL98470A patent/IL98470A0/xx unknown
- 1991-06-14 IE IE202591A patent/IE912025A1/en unknown
- 1991-06-14 NZ NZ238546A patent/NZ238546A/en unknown
- 1991-06-18 MA MA22462A patent/MA22199A1/fr unknown
- 1991-06-19 AP APAP/P/1991/000285A patent/AP215A/en active
- 1991-06-19 PT PT98035A patent/PT98035A/pt not_active Application Discontinuation
- 1991-06-19 TN TNTNSN91049A patent/TNSN91049A1/fr unknown
- 1991-06-20 CN CN91105024A patent/CN1058212A/zh active Pending
- 1991-06-20 CZ CS911894A patent/CZ279772B6/cs unknown
- 1991-06-20 IS IS3721A patent/IS3721A7/is unknown
-
1992
- 1992-11-27 OA OA60306A patent/OA09682A/en unknown
- 1992-12-10 NO NO92924775A patent/NO924775L/no unknown
- 1992-12-18 FI FI925766A patent/FI925766A7/fi not_active Application Discontinuation
- 1992-12-18 BG BG097200A patent/BG97200A/bg unknown
-
1993
- 1993-08-27 LV LV931045A patent/LV10953A/xx unknown
- 1993-12-30 LT LTIP1713A patent/LT3977B/lt not_active IP Right Cessation
- 1993-12-30 LT LTIP1712A patent/LT3952B/lt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| SE9002206D0 (sv) | 1990-06-20 |
| MA22199A1 (fr) | 1992-04-01 |
| IE912025A1 (en) | 1992-01-01 |
| EP0535081A1 (en) | 1993-04-07 |
| AP9100285A0 (en) | 1991-07-31 |
| CN1058212A (zh) | 1992-01-29 |
| TW216418B (cs) | 1993-11-21 |
| LT3952B (en) | 1996-05-27 |
| AU649453B2 (en) | 1994-05-26 |
| LTIP1713A (en) | 1995-08-25 |
| LV10953A (lv) | 1995-12-20 |
| NZ238546A (en) | 1994-03-25 |
| CZ279772B6 (cs) | 1995-06-14 |
| OA09682A (en) | 1993-05-15 |
| HU9204033D0 (en) | 1993-03-29 |
| LTIP1712A (en) | 1995-08-25 |
| AP215A (en) | 1992-09-02 |
| WO1991019711A1 (en) | 1991-12-26 |
| NO924775D0 (no) | 1992-12-10 |
| CA2083714A1 (en) | 1991-12-21 |
| JPH05507713A (ja) | 1993-11-04 |
| RO110493B1 (ro) | 1996-01-30 |
| FI925766A0 (fi) | 1992-12-18 |
| AU8009791A (en) | 1992-01-07 |
| PT98035A (pt) | 1992-03-31 |
| TNSN91049A1 (fr) | 1992-10-25 |
| LT3977B (en) | 1996-06-25 |
| ZA914297B (en) | 1992-03-25 |
| HUT62881A (en) | 1993-06-28 |
| YU104191A (sh) | 1994-01-20 |
| IL98470A0 (en) | 1992-07-15 |
| ZA914296B (en) | 1992-03-25 |
| NO924775L (no) | 1992-12-10 |
| FI925766A7 (fi) | 1992-12-18 |
| CS189491A3 (en) | 1992-04-15 |
| IS3721A7 (is) | 1991-12-21 |
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