BG63803B1 - Фармацевтичен състав за профилактика и лечение надиабетични усложнения - Google Patents
Фармацевтичен състав за профилактика и лечение надиабетични усложнения Download PDFInfo
- Publication number
- BG63803B1 BG63803B1 BG102633A BG10263398A BG63803B1 BG 63803 B1 BG63803 B1 BG 63803B1 BG 102633 A BG102633 A BG 102633A BG 10263398 A BG10263398 A BG 10263398A BG 63803 B1 BG63803 B1 BG 63803B1
- Authority
- BG
- Bulgaria
- Prior art keywords
- treatment
- pharmaceutically acceptable
- prevention
- compound
- benzyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/60—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP34016195 | 1995-12-27 | ||
PCT/JP1996/003776 WO1997024333A1 (fr) | 1995-12-27 | 1996-12-24 | Composes de prevention/traitement s'appliquant aux complications de diabetes |
Publications (2)
Publication Number | Publication Date |
---|---|
BG102633A BG102633A (en) | 1999-09-30 |
BG63803B1 true BG63803B1 (bg) | 2003-01-31 |
Family
ID=18334321
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG102633A BG63803B1 (bg) | 1995-12-27 | 1998-07-15 | Фармацевтичен състав за профилактика и лечение надиабетични усложнения |
Country Status (23)
Country | Link |
---|---|
US (8) | US6060496A (fr) |
EP (2) | EP0881218B1 (fr) |
JP (1) | JP3448869B2 (fr) |
KR (2) | KR100471351B1 (fr) |
CN (2) | CN1159009C (fr) |
AT (1) | ATE252563T1 (fr) |
AU (1) | AU716332B2 (fr) |
BG (1) | BG63803B1 (fr) |
BR (1) | BR9612316A (fr) |
CA (1) | CA2241856C (fr) |
CZ (1) | CZ294485B6 (fr) |
DE (1) | DE69630465T2 (fr) |
EE (1) | EE03524B1 (fr) |
ES (1) | ES2210399T3 (fr) |
HK (1) | HK1015777A1 (fr) |
HU (1) | HUP0000422A3 (fr) |
IL (1) | IL125104A (fr) |
IS (1) | IS4784A (fr) |
MX (1) | MX9805317A (fr) |
NO (1) | NO316494B1 (fr) |
NZ (1) | NZ324454A (fr) |
RU (1) | RU2173148C2 (fr) |
WO (1) | WO1997024333A1 (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE252563T1 (de) * | 1995-12-27 | 2003-11-15 | Mitsubishi Pharma Corp | Vorsorge-/heilmittel fur die komplikationen von diabetes |
EP1186296B1 (fr) * | 1999-05-25 | 2007-04-18 | Mitsubishi Pharma Corporation | Promoteurs de l'expression de la glycoproteine associee a la myeline (mag) |
US6482844B1 (en) * | 2000-04-07 | 2002-11-19 | Neurogen Corporation | 1-benzylimidazole derivatives |
AU2001215513A1 (en) * | 2000-11-24 | 2002-06-03 | Toyo Shinyaku Co., Ltd. | Foods containing young wheat leaf powder |
DE10229180A1 (de) | 2002-06-28 | 2004-01-29 | Aventis Pharma Deutschland Gmbh | Verwendung von Vasopeptidase-Inhibitoren bei der Behandlung von metabolischen Erkrankungen, Nephropathie und mit AGE assoziierten Erkrankungen |
EP1535077A2 (fr) * | 2002-08-29 | 2005-06-01 | University Of Florida Research Foundation, Inc. | Equilibre des prostaglandines altere par mediation de cox-2 dans les complications liees au diabete |
GB0314945D0 (en) * | 2003-06-26 | 2003-07-30 | Black & Decker Inc | Vacuum cleaner |
EP2234608A2 (fr) | 2007-12-11 | 2010-10-06 | Viamet Pharmaceuticals, Inc. | Inhibiteurs de métalloenzymes utilisant des fractions de liaison à un métal en combinaison avec des fractions de ciblage |
RU2741715C1 (ru) * | 2020-03-20 | 2021-01-28 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Пермский государственный медицинский университет имени академика Е.А. Вагнера" Министерства здравоохранения Российской Федерации | Способ прогнозирования формирования микрососудистых осложнений сахарного диабета 2 типа |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK531479A (da) * | 1979-01-19 | 1980-07-20 | Pfizer | Fremgangsmaade til fremstilling af imidazolderivater og salte deraf |
JPS61277670A (ja) * | 1985-06-03 | 1986-12-08 | Yoshitomi Pharmaceut Ind Ltd | イミダゾ−ル誘導体 |
US4661603A (en) * | 1982-03-03 | 1987-04-28 | Yoshitomi Pharmaceutical Industries, Ltd. | Imidazole derivatives |
JPS6147477A (ja) * | 1984-08-14 | 1986-03-07 | Kowa Co | 新規1,4−ジヒドロピリジン−3,5−ジカルボン酸エステル誘導体 |
JPS63119425A (ja) * | 1986-11-07 | 1988-05-24 | Yoshitomi Pharmaceut Ind Ltd | 免疫機能改善薬 |
JPS63310825A (ja) * | 1987-06-03 | 1988-12-19 | フアルミタリア・カルロ・エルバ・エツセ・エルレ・エルレ | 医薬に有用な二環式化合物のn−イミダゾリル誘導体 |
EP0379579A4 (en) * | 1988-02-03 | 1991-01-02 | Yoshitomi Pharmaceutical Industries, Ltd. | Pharmaceutical composition having improved releasability |
JP2814513B2 (ja) * | 1988-02-03 | 1998-10-22 | 吉富製薬株式会社 | 溶出性の改良された製剤組成物 |
WO1990012009A1 (fr) | 1989-03-31 | 1990-10-18 | Kyoto Pharmaceutical Industries, Ltd. | Nouveaux derives d'imidazole, leur production, et leurs emplois comme medicaments |
JPH037281A (ja) * | 1989-03-31 | 1991-01-14 | Kyoto Yakuhin Kogyo Kk | 新規イミダゾール誘導体およびその医薬用途 |
US5401851A (en) * | 1992-06-03 | 1995-03-28 | Eli Lilly And Company | Angiotensin II antagonists |
ATE252563T1 (de) | 1995-12-27 | 2003-11-15 | Mitsubishi Pharma Corp | Vorsorge-/heilmittel fur die komplikationen von diabetes |
-
1996
- 1996-12-24 AT AT96942640T patent/ATE252563T1/de not_active IP Right Cessation
- 1996-12-24 DE DE69630465T patent/DE69630465T2/de not_active Expired - Lifetime
- 1996-12-24 KR KR10-2004-7004476A patent/KR100471351B1/ko not_active IP Right Cessation
- 1996-12-24 CA CA002241856A patent/CA2241856C/fr not_active Expired - Fee Related
- 1996-12-24 EP EP96942640A patent/EP0881218B1/fr not_active Expired - Lifetime
- 1996-12-24 AU AU11735/97A patent/AU716332B2/en not_active Ceased
- 1996-12-24 IL IL12510496A patent/IL125104A/en not_active IP Right Cessation
- 1996-12-24 US US09/091,993 patent/US6060496A/en not_active Expired - Lifetime
- 1996-12-24 NZ NZ324454A patent/NZ324454A/xx unknown
- 1996-12-24 JP JP52417797A patent/JP3448869B2/ja not_active Expired - Fee Related
- 1996-12-24 ES ES96942640T patent/ES2210399T3/es not_active Expired - Lifetime
- 1996-12-24 BR BR9612316A patent/BR9612316A/pt not_active Application Discontinuation
- 1996-12-24 RU RU98113956/14A patent/RU2173148C2/ru not_active IP Right Cessation
- 1996-12-24 CN CNB011172541A patent/CN1159009C/zh not_active Expired - Fee Related
- 1996-12-24 CZ CZ19982012A patent/CZ294485B6/cs not_active IP Right Cessation
- 1996-12-24 WO PCT/JP1996/003776 patent/WO1997024333A1/fr active IP Right Grant
- 1996-12-24 KR KR10-1998-0702751A patent/KR100443891B1/ko not_active IP Right Cessation
- 1996-12-24 EE EE9800208A patent/EE03524B1/xx not_active IP Right Cessation
- 1996-12-24 HU HU0000422A patent/HUP0000422A3/hu unknown
- 1996-12-24 CN CN96180052A patent/CN1092645C/zh not_active Expired - Fee Related
- 1996-12-24 EP EP03022894A patent/EP1394151A1/fr not_active Withdrawn
-
1998
- 1998-06-26 IS IS4784A patent/IS4784A/is unknown
- 1998-06-26 NO NO982988A patent/NO316494B1/no not_active IP Right Cessation
- 1998-06-29 MX MX9805317A patent/MX9805317A/es not_active IP Right Cessation
- 1998-07-15 BG BG102633A patent/BG63803B1/bg unknown
-
1999
- 1999-03-02 HK HK99100842A patent/HK1015777A1/xx not_active IP Right Cessation
-
2000
- 2000-02-04 US US09/498,481 patent/US6258834B1/en not_active Expired - Lifetime
-
2001
- 2001-05-08 US US09/850,000 patent/US20010036957A1/en not_active Abandoned
-
2002
- 2002-02-25 US US10/080,660 patent/US20020169194A1/en not_active Abandoned
-
2003
- 2003-01-30 US US10/354,136 patent/US20030130332A1/en not_active Abandoned
-
2004
- 2004-02-24 US US10/784,232 patent/US20040171663A1/en not_active Abandoned
-
2005
- 2005-06-15 US US11/152,376 patent/US20050239856A1/en not_active Abandoned
-
2006
- 2006-02-28 US US11/363,202 patent/US20060148875A1/en not_active Abandoned
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