BG63711B1 - Фармацевтичен препарат, съдържащ протеиназен инхибитор и моноглицерид - Google Patents

Фармацевтичен препарат, съдържащ протеиназен инхибитор и моноглицерид Download PDF

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Publication number
BG63711B1
BG63711B1 BG102106A BG10210697A BG63711B1 BG 63711 B1 BG63711 B1 BG 63711B1 BG 102106 A BG102106 A BG 102106A BG 10210697 A BG10210697 A BG 10210697A BG 63711 B1 BG63711 B1 BG 63711B1
Authority
BG
Bulgaria
Prior art keywords
hydroxy
phenyl
amino
acid
butyl
Prior art date
Application number
BG102106A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG102106A (en
Inventor
Anne BAILEY
Josephine FERDINANDO
Navnit Shah
Original Assignee
F. Hoffmann- La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/616,233 external-priority patent/US6008228A/en
Application filed by F. Hoffmann- La Roche Ag filed Critical F. Hoffmann- La Roche Ag
Publication of BG102106A publication Critical patent/BG102106A/xx
Publication of BG63711B1 publication Critical patent/BG63711B1/bg

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/472Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
BG102106A 1995-06-06 1997-12-05 Фармацевтичен препарат, съдържащ протеиназен инхибитор и моноглицерид BG63711B1 (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46849395A 1995-06-06 1995-06-06
US08/616,233 US6008228A (en) 1995-06-06 1996-05-07 Pharmaceutical compositions containing proteinase inhibitors
PCT/EP1996/002431 WO1996039142A1 (en) 1995-06-06 1996-06-04 Pharmaceutical composition comprising a proteinase inhibitor and a monoglyceride

Publications (2)

Publication Number Publication Date
BG102106A BG102106A (en) 1998-08-31
BG63711B1 true BG63711B1 (bg) 2002-10-31

Family

ID=27042422

Family Applications (1)

Application Number Title Priority Date Filing Date
BG102106A BG63711B1 (bg) 1995-06-06 1997-12-05 Фармацевтичен препарат, съдържащ протеиназен инхибитор и моноглицерид

Country Status (27)

Country Link
EP (1) EP0831826B1 (pt)
JP (1) JP3238412B2 (pt)
CN (1) CN1092960C (pt)
AT (1) ATE226075T1 (pt)
AU (1) AU709796B2 (pt)
BG (1) BG63711B1 (pt)
BR (1) BR9610842A (pt)
CA (1) CA2224125C (pt)
CY (1) CY2373B1 (pt)
CZ (1) CZ292192B6 (pt)
DE (1) DE69624354T2 (pt)
DK (1) DK0831826T3 (pt)
EA (1) EA001413B1 (pt)
ES (1) ES2182996T3 (pt)
HK (1) HK1010136A1 (pt)
HU (1) HU223899B1 (pt)
IL (1) IL122353A0 (pt)
IS (1) IS2661B (pt)
MX (1) MX9709193A (pt)
NO (1) NO324531B1 (pt)
NZ (1) NZ311646A (pt)
OA (1) OA10546A (pt)
PL (1) PL184820B1 (pt)
PT (1) PT831826E (pt)
SK (1) SK282121B6 (pt)
TR (1) TR199701541T1 (pt)
WO (1) WO1996039142A1 (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9810729B1 (pt) 1997-07-29 2010-07-13 composição farmacêutica para compostos lipofìlicos ácidos disposta como uma formulação auto-emulsificante.
NZ502567A (en) 1997-07-29 2002-03-28 Upjohn Co Self-emulsifying formulation for lipophilic compounds containing a pyranone and a mixture of monoglycerides and diglycerides
US7258869B1 (en) 1999-02-08 2007-08-21 Alza Corporation Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle
KR20080045300A (ko) * 1999-02-08 2008-05-22 알자 코포레이션 안정한 비수성 단일상 점성 비히클 및 그 비히클을이용하는 제형물
US7919109B2 (en) 1999-02-08 2011-04-05 Intarcia Therapeutics, Inc. Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles
US6956048B2 (en) 1999-03-31 2005-10-18 Pharmacia & Upjohn Company Pharmaceutical emulsions for retroviral protease inhibitors
US6309663B1 (en) * 1999-08-17 2001-10-30 Lipocine Inc. Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents
BR0202252A (pt) 2002-06-12 2004-06-29 Cristalia Prod Quimicos Farm Composição farmacêutica solúvel estável para administração de inibidores da hiv protease e processo de obtenção de composições farmacêuticas concentradas para a administração de inibidores da hiv protease
US7731947B2 (en) 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
DE602007009377D1 (de) 2006-05-30 2010-11-04 Intarcia Therapeutics Inc Zweiteiliger flussmodulator mit einem internen kanal für ein osmotisches ausgabesystem
WO2008133908A2 (en) 2007-04-23 2008-11-06 Intarcia Therapeutics, Inc. Suspension formulations of insulinotropic peptides and uses thereof
DK2240155T3 (da) 2008-02-13 2012-09-17 Intarcia Therapeutics Inc Indretninger, formuleringer og fremgangsmåder til levering af flere gavnlige midler
EP2108705A1 (en) 2008-04-08 2009-10-14 Universität Duisburg-Essen Method for analysing the epigenetic status of the HtrA 1 gene in a biological sample
MX352878B (es) 2009-09-28 2017-12-13 Intarcia Therapeutics Inc Establecimiento y/o terminacion rapidos de suministro de estado estable sustancial de farmaco.
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
EP4278996A3 (en) 2015-06-03 2024-01-24 i2o Therapeutics, Inc. Implant placement systems
EP3458084B1 (en) 2016-05-16 2020-04-01 Intarcia Therapeutics, Inc Glucagon-receptor selective polypeptides and methods of use thereof
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
MX2019008006A (es) 2017-01-03 2019-08-29 Intarcia Therapeutics Inc Metodos que comprenden la administracion continua de un agonista del receptor de glp-1 y la co-administracion de un farmaco.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8927913D0 (en) * 1989-12-11 1990-02-14 Hoffmann La Roche Amino acid derivatives
IL110752A (en) * 1993-09-13 2000-07-26 Abbott Lab Liquid semi-solid or solid pharmaceutical composition for an HIV protease inhibitor

Also Published As

Publication number Publication date
NO975665L (no) 1998-02-05
SK282121B6 (sk) 2001-11-06
NO975665D0 (no) 1997-12-05
AU709796B2 (en) 1999-09-09
BG102106A (en) 1998-08-31
HUP9801905A2 (hu) 1999-05-28
TR199701541T1 (xx) 1998-03-21
PL184820B1 (pl) 2002-12-31
SK162797A3 (en) 1998-05-06
MX9709193A (es) 1998-03-31
EA001413B1 (ru) 2001-02-26
DE69624354T2 (de) 2003-06-05
HK1010136A1 (en) 1999-06-17
CA2224125A1 (en) 1996-12-12
HUP9801905A3 (en) 2001-04-28
WO1996039142A1 (en) 1996-12-12
EA199800023A1 (ru) 1998-08-27
CN1186434A (zh) 1998-07-01
BR9610842A (pt) 1999-07-13
IL122353A0 (en) 1998-04-05
DK0831826T3 (da) 2003-02-03
EP0831826B1 (en) 2002-10-16
ES2182996T3 (es) 2003-03-16
CN1092960C (zh) 2002-10-23
PL323860A1 (en) 1998-04-27
CY2373B1 (en) 2004-06-04
AU6300496A (en) 1996-12-24
OA10546A (en) 2002-05-29
CZ292192B6 (cs) 2003-08-13
ATE226075T1 (de) 2002-11-15
JPH10507202A (ja) 1998-07-14
EP0831826A1 (en) 1998-04-01
JP3238412B2 (ja) 2001-12-17
DE69624354D1 (de) 2002-11-21
NO324531B1 (no) 2007-11-12
NZ311646A (en) 2000-02-28
CA2224125C (en) 2004-09-28
PT831826E (pt) 2003-02-28
IS4627A (is) 1997-12-04
IS2661B (is) 2010-08-15
HU223899B1 (hu) 2005-03-29
CZ380397A3 (cs) 1998-03-18

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