BG63693B1 - Таксоиди, тяхното получаване и фармацевтични състави, които ги съдържат - Google Patents

Таксоиди, тяхното получаване и фармацевтични състави, които ги съдържат Download PDF

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Publication number
BG63693B1
BG63693B1 BG102753A BG10275398A BG63693B1 BG 63693 B1 BG63693 B1 BG 63693B1 BG 102753 A BG102753 A BG 102753A BG 10275398 A BG10275398 A BG 10275398A BG 63693 B1 BG63693 B1 BG 63693B1
Authority
BG
Bulgaria
Prior art keywords
radical
carbon atoms
radicals
alkyl
atoms
Prior art date
Application number
BG102753A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG102753A (en
Inventor
Herve Bouchard
Jean-Dominique Bourzat
Alain Commercon
Original Assignee
Rhone-Poulenc Rorer S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone-Poulenc Rorer S.A. filed Critical Rhone-Poulenc Rorer S.A.
Publication of BG102753A publication Critical patent/BG102753A/xx
Publication of BG63693B1 publication Critical patent/BG63693B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/06—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
BG102753A 1996-03-06 1998-09-04 Таксоиди, тяхното получаване и фармацевтични състави, които ги съдържат BG63693B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9602804A FR2745814B1 (fr) 1996-03-06 1996-03-06 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR1997/000386 WO1997032869A1 (fr) 1996-03-06 1997-03-05 Taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
BG102753A BG102753A (en) 1999-09-30
BG63693B1 true BG63693B1 (bg) 2002-09-30

Family

ID=9489910

Family Applications (1)

Application Number Title Priority Date Filing Date
BG102753A BG63693B1 (bg) 1996-03-06 1998-09-04 Таксоиди, тяхното получаване и фармацевтични състави, които ги съдържат

Country Status (34)

Country Link
US (1) US6160135A (de)
EP (1) EP0885208B1 (de)
JP (1) JP2000506158A (de)
KR (1) KR19990087398A (de)
CN (1) CN1210525A (de)
AP (1) AP1023A (de)
AT (1) ATE204266T1 (de)
AU (1) AU715228B2 (de)
BG (1) BG63693B1 (de)
BR (1) BR9707887A (de)
CA (1) CA2248195A1 (de)
CZ (1) CZ283498A3 (de)
DE (1) DE69706146T2 (de)
DK (1) DK0885208T3 (de)
EA (1) EA001516B1 (de)
EE (1) EE03611B1 (de)
ES (1) ES2161446T3 (de)
FR (1) FR2745814B1 (de)
GE (1) GEP20012517B (de)
GR (1) GR3036410T3 (de)
HU (1) HUP9902425A3 (de)
IL (1) IL125998A (de)
IS (1) IS4809A (de)
NO (1) NO983472L (de)
NZ (1) NZ331040A (de)
OA (1) OA10855A (de)
PL (1) PL328691A1 (de)
PT (1) PT885208E (de)
SK (1) SK121598A3 (de)
TR (1) TR199801732T2 (de)
TW (1) TW474928B (de)
WO (1) WO1997032869A1 (de)
YU (1) YU38398A (de)
ZA (1) ZA971746B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5973160A (en) 1992-12-23 1999-10-26 Poss; Michael A. Methods for the preparation of novel sidechain-bearing taxanes
MA23823A1 (fr) 1995-03-27 1996-10-01 Aventis Pharma Sa Nouveaux taxoides, leur preparation et les compositions qui les contiennent
US6372780B2 (en) 1995-03-27 2002-04-16 Aventis Pharma S.A. Methods of treating cell lines expressing multidrug resistance P-glycoprotein
CN1221539C (zh) * 1997-12-19 2005-10-05 株式会社益力多本社 紫杉烷衍生物
EP1020188A1 (de) * 1999-01-13 2000-07-19 Aventis Pharma S.A. Neue Verwendung von Taxoid-Derivaten
NZ514074A (en) 2000-02-02 2004-03-26 Univ Florida State Res Found C10 carbonate substituted taxanes as antitumor agents
AR030188A1 (es) * 2000-02-02 2003-08-13 Univ Florida State Res Found Compuestos de taxano sustituidos con esteres en el c7; composiciones farmaceuticas que los contienen y proceso para tratar un sujeto mamifero que sufre de una condicion que responde a los taxanos
FR2859996B1 (fr) * 2003-09-19 2006-02-03 Aventis Pharma Sa Solvat acetonique du dimethoxy docetaxel et son procede de preparation
GT200500041A (es) 2004-03-05 2005-10-24 Taxanos con sustituyente lactiloxilo en el c7
WO2009023967A1 (en) * 2007-08-22 2009-02-26 6570763 Canada Inc. Process for converting 9-dihydro-13-acetylbaccatin iii into docetaxel or paclitaxel
FR2926551A1 (fr) * 2008-01-17 2009-07-24 Aventis Pharma Sa Formes cristallines du dimethoxy docetaxel et leurs procedes de preparation
CA2779009A1 (en) 2009-10-29 2011-05-05 Aventis Pharma S.A. Novel antitumoral use of cabazitaxel
CN104650012A (zh) 2013-11-22 2015-05-27 天士力控股集团有限公司 一种紫杉烷类化合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5136060A (en) * 1989-11-14 1992-08-04 Florida State University Method for preparation of taxol using an oxazinone
KR930702323A (ko) * 1991-07-17 1993-09-08 하지메 나까가와 항종양 활성을 가진 화합물(nsc-lsc1) 및 그의 제조방법
CA2100808A1 (en) * 1992-10-01 1994-04-02 Vittorio Farina Deoxy paclitaxels
ES2241923T3 (es) * 1993-03-22 2005-11-01 Florida State University Beta-lactanas utiles en la preparacion de taxanos que tienen una cadena lateral furilo o tienilo sustituido.
FR2711369B1 (fr) * 1993-10-20 1995-11-17 Rhone Poulenc Rorer Sa Nouveaux taxoïdes, leur préparation et les compositions qui les contiennent.
AU684218B2 (en) * 1994-07-26 1997-12-04 Indena S.P.A. Semi-synthetic taxanes with anti-tumoural activity
US6201140B1 (en) * 1994-07-28 2001-03-13 Bristol-Myers Squibb Company 7-0-ethers of taxane derivatives

Also Published As

Publication number Publication date
HUP9902425A3 (en) 2001-08-28
NZ331040A (en) 2000-02-28
GR3036410T3 (en) 2001-11-30
BR9707887A (pt) 1999-09-21
AP9801335A0 (en) 1998-09-30
TW474928B (en) 2002-02-01
EA001516B1 (ru) 2001-04-23
FR2745814A1 (fr) 1997-09-12
HUP9902425A2 (hu) 2001-04-28
EA199800795A1 (ru) 1999-02-25
JP2000506158A (ja) 2000-05-23
BG102753A (en) 1999-09-30
GEP20012517B (en) 2001-08-27
KR19990087398A (ko) 1999-12-27
DK0885208T3 (da) 2001-10-15
DE69706146T2 (de) 2002-05-02
ES2161446T3 (es) 2001-12-01
EP0885208B1 (de) 2001-08-16
AU2030297A (en) 1997-09-22
YU38398A (sh) 1999-07-28
IL125998A0 (en) 1999-04-11
EE9800264A (et) 1999-02-15
EE03611B1 (et) 2002-02-15
ZA971746B (en) 1997-09-16
ATE204266T1 (de) 2001-09-15
EP0885208A1 (de) 1998-12-23
IL125998A (en) 2002-02-10
FR2745814B1 (fr) 1998-04-03
DE69706146D1 (de) 2001-09-20
AU715228B2 (en) 2000-01-20
PT885208E (pt) 2001-11-30
NO983472D0 (no) 1998-07-28
SK121598A3 (en) 1999-01-11
TR199801732T2 (xx) 1998-12-21
CA2248195A1 (fr) 1997-09-12
IS4809A (is) 1998-07-24
NO983472L (no) 1998-07-28
WO1997032869A1 (fr) 1997-09-12
US6160135A (en) 2000-12-12
CN1210525A (zh) 1999-03-10
CZ283498A3 (cs) 1999-01-13
AP1023A (en) 2001-11-16
PL328691A1 (en) 1999-02-15
OA10855A (fr) 2003-02-05

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