BG63159B1 - Производни на заместени 4-бифенил-4-хидрокси-маслени киселини като инхибитори на матрични металопротеази - Google Patents
Производни на заместени 4-бифенил-4-хидрокси-маслени киселини като инхибитори на матрични металопротеази Download PDFInfo
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- C07C59/40—Unsaturated compounds
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- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
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- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
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- C07C2601/00—Systems containing only non-condensed rings
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- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
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- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
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- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
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- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
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- Hematology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3026496P | 1996-10-31 | 1996-10-31 | |
| PCT/US1997/019960 WO1998022436A1 (en) | 1996-10-31 | 1997-10-30 | Substituted 4-biphenyl-4-hydroxybutyric acid derivatives as matrix metalloprotease inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BG103426A BG103426A (en) | 2000-01-31 |
| BG63159B1 true BG63159B1 (bg) | 2001-05-31 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG103426A BG63159B1 (bg) | 1996-10-31 | 1999-05-21 | Производни на заместени 4-бифенил-4-хидрокси-маслени киселини като инхибитори на матрични металопротеази |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US5939583A (pt) |
| EP (1) | EP0937036B1 (pt) |
| JP (1) | JP2001505877A (pt) |
| KR (1) | KR20000052899A (pt) |
| CN (1) | CN1140508C (pt) |
| AR (1) | AR009137A1 (pt) |
| AT (1) | ATE210112T1 (pt) |
| AU (1) | AU731830B2 (pt) |
| BG (1) | BG63159B1 (pt) |
| BR (1) | BR9712707A (pt) |
| CA (1) | CA2268770A1 (pt) |
| CZ (1) | CZ148599A3 (pt) |
| DE (1) | DE69708909T2 (pt) |
| DK (1) | DK0937036T3 (pt) |
| EE (1) | EE03745B1 (pt) |
| ES (1) | ES2167021T3 (pt) |
| HU (1) | HUP9904664A3 (pt) |
| ID (1) | ID18712A (pt) |
| IL (1) | IL129420A (pt) |
| MY (1) | MY117687A (pt) |
| NO (1) | NO312629B1 (pt) |
| PL (1) | PL333112A1 (pt) |
| PT (1) | PT937036E (pt) |
| SK (1) | SK58399A3 (pt) |
| TR (1) | TR199900945T2 (pt) |
| TW (1) | TW464642B (pt) |
| UA (1) | UA57047C2 (pt) |
| WO (1) | WO1998022436A1 (pt) |
| ZA (1) | ZA979756B (pt) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2780402B1 (fr) * | 1998-06-30 | 2001-04-27 | Adir | Nouveaux composes acides carboxyliques et hydroxamiques inhibiteurs de metalloproteases, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| TR200101970T2 (tr) | 1998-12-30 | 2002-03-21 | Bayer Aktiengesellschaft | Solunum yollarì hastalìklarìnìn tedavisinde matriks metaloproteaz inhibitrleri olarak ikameli 4-biarilbutirik ve 5-biarilpentanoik asit trevlerinin kullanìlmasì |
| EP1031349A1 (en) * | 1999-02-25 | 2000-08-30 | Bayer Aktiengesellschaft | Use of substituted 4-biarylbutyric and 5-biarylpentanoic acid derivatives for the treatment of cerebral diseases |
| DE10058163C2 (de) * | 2000-11-22 | 2003-07-10 | Bebig Isotopen Und Medizintech | Verfahren und Applikator zum Positionieren und/oder Auswerfen von Strahlenquellen über Hohlnadeln in biologisches Gewebe |
| EP1594459B1 (en) | 2002-12-30 | 2010-02-17 | Angiotech International Ag | Drug delivery from rapid gelling polymer composition |
| US8460243B2 (en) | 2003-06-10 | 2013-06-11 | Abbott Diabetes Care Inc. | Glucose measuring module and insulin pump combination |
| US7722536B2 (en) | 2003-07-15 | 2010-05-25 | Abbott Diabetes Care Inc. | Glucose measuring device integrated into a holster for a personal area network device |
| CA2572455C (en) | 2004-06-04 | 2014-10-28 | Therasense, Inc. | Diabetes care host-client architecture and data management system |
| JP4994247B2 (ja) * | 2005-02-22 | 2012-08-08 | ランバクシー ラボラトリーズ リミテッド | 喘息及びそのほかの疾病の治療用のマトリクスメタロプロテイナーゼ阻害剤としての５−フェニルペンタン酸誘導体 |
| US7414142B2 (en) | 2005-09-19 | 2008-08-19 | Wyeth | 5-aryl-indan-1-one oximes and analogs useful as progesterone receptor modulators |
| US7319152B2 (en) | 2005-09-19 | 2008-01-15 | Wyeth | 5-Aryl-indan-1-one and analogs useful as progesterone receptor modulators |
| WO2007122743A1 (ja) * | 2006-04-17 | 2007-11-01 | Sumitomo Chemical Company, Limited | 多環式ラクタム類の製造方法 |
| CA2661299A1 (en) * | 2006-08-22 | 2008-02-28 | Ranbaxy Laboratories Limited | Beta -hydroxy-and amino-substituted carboxylic acids as matrix metalloproteinase inhibitors |
| US10136845B2 (en) | 2011-02-28 | 2018-11-27 | Abbott Diabetes Care Inc. | Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same |
| JP6804352B2 (ja) * | 2017-03-22 | 2020-12-23 | 大阪瓦斯株式会社 | コラゲナーゼｍｍｐ１及び３の産生抑制剤 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1040735A (en) * | 1964-07-23 | 1966-09-01 | British Drug Houses Ltd | 4-aryl-3-hydroxybutyric acid and esters, amides and salts thereof |
| US4021479A (en) * | 1971-03-17 | 1977-05-03 | Boehringer Ingelheim Gmbh | Derivatives of 4-(4-biphenylyl)-butyric acid |
| ES446581A1 (es) * | 1975-04-04 | 1977-06-16 | Boots Co Ltd | Un procedimiento para preparar acidos 2-arilpropionicos. |
| US4151302A (en) * | 1975-06-28 | 1979-04-24 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Araliphatic dihalogen compounds composition and method of use |
| US4168385A (en) * | 1975-09-25 | 1979-09-18 | American Cyanamid Company | Hypolipemic phenylacetic acid derivatives |
| US4567289A (en) * | 1979-08-17 | 1986-01-28 | Merck & Co., Inc. | Substituted pyranone inhibitors of cholesterol synthesis |
| JPS60169462A (ja) * | 1984-02-15 | 1985-09-02 | Sumitomo Chem Co Ltd | 光学活性なフエニルセリン誘導体の製造法 |
| CA1223602A (en) * | 1983-05-25 | 1987-06-30 | Naohito Ohashi | Process for producing 3-(3,4-dihydroxyphenyl) serine |
| US4855321A (en) * | 1986-01-31 | 1989-08-08 | Merck & Co., Inc. | Antihypercholesterolemic compounds |
| US5001128A (en) * | 1987-12-21 | 1991-03-19 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | HMG-COA reductase inhibitors |
| US5393780A (en) * | 1993-03-26 | 1995-02-28 | Fujirebio Inc. | 4-fluorobiphenyl derivatives |
| US5789434A (en) * | 1994-11-15 | 1998-08-04 | Bayer Corporation | Derivatives of substituted 4-biarylbutyric acid as matrix metalloprotease inhibitors |
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1997
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- 1997-10-30 CZ CZ991485A patent/CZ148599A3/cs unknown
- 1997-10-30 ZA ZA9709756A patent/ZA979756B/xx unknown
- 1997-10-30 TW TW086116305A patent/TW464642B/zh not_active IP Right Cessation
- 1997-10-30 BR BR9712707-8A patent/BR9712707A/pt unknown
- 1997-10-30 AU AU51024/98A patent/AU731830B2/en not_active Ceased
- 1997-10-30 UA UA99052950A patent/UA57047C2/uk unknown
- 1997-10-30 IL IL12942097A patent/IL129420A/xx not_active IP Right Cessation
- 1997-10-30 PL PL97333112A patent/PL333112A1/xx unknown
- 1997-10-30 DK DK97945585T patent/DK0937036T3/da active
- 1997-10-30 HU HU9904664A patent/HUP9904664A3/hu unknown
- 1997-10-30 WO PCT/US1997/019960 patent/WO1998022436A1/en not_active Application Discontinuation
- 1997-10-30 KR KR1019990703763A patent/KR20000052899A/ko not_active Application Discontinuation
- 1997-10-30 PT PT97945585T patent/PT937036E/pt unknown
- 1997-10-30 ES ES97945585T patent/ES2167021T3/es not_active Expired - Lifetime
- 1997-10-30 EE EEP199900180A patent/EE03745B1/xx not_active IP Right Cessation
- 1997-10-30 JP JP52367798A patent/JP2001505877A/ja active Pending
- 1997-10-30 AR ARP970105054A patent/AR009137A1/es unknown
- 1997-10-30 SK SK583-99A patent/SK58399A3/sk unknown
- 1997-10-30 TR TR1999/00945T patent/TR199900945T2/xx unknown
- 1997-10-30 AT AT97945585T patent/ATE210112T1/de not_active IP Right Cessation
- 1997-10-30 CA CA002268770A patent/CA2268770A1/en not_active Abandoned
- 1997-10-30 DE DE69708909T patent/DE69708909T2/de not_active Expired - Fee Related
- 1997-10-30 CN CNB971809100A patent/CN1140508C/zh not_active Expired - Fee Related
- 1997-10-30 EP EP97945585A patent/EP0937036B1/en not_active Expired - Lifetime
- 1997-10-30 US US08/960,921 patent/US5939583A/en not_active Expired - Fee Related
- 1997-10-31 ID IDP973569A patent/ID18712A/id unknown
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1999
- 1999-04-27 NO NO19991994A patent/NO312629B1/no not_active IP Right Cessation
- 1999-05-21 BG BG103426A patent/BG63159B1/bg unknown
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