BG62887B1 - Нафтиламиди като средства, повлияващи централната нервна система - Google Patents
Нафтиламиди като средства, повлияващи централната нервна система Download PDFInfo
- Publication number
- BG62887B1 BG62887B1 BG100830A BG10083096A BG62887B1 BG 62887 B1 BG62887 B1 BG 62887B1 BG 100830 A BG100830 A BG 100830A BG 10083096 A BG10083096 A BG 10083096A BG 62887 B1 BG62887 B1 BG 62887B1
- Authority
- BG
- Bulgaria
- Prior art keywords
- ethyl
- naphthalenecarboxamide
- bromo
- piperazinyl
- methoxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
- C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/66—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Liquid Carbonaceous Fuels (AREA)
- Quinoline Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Furan Compounds (AREA)
- Chemical And Physical Treatments For Wood And The Like (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/217,395 US5395835A (en) | 1994-03-24 | 1994-03-24 | Naphthalamides as central nervous system agents |
| PCT/US1995/001974 WO1995025727A1 (en) | 1994-03-24 | 1995-02-16 | Naphthylamides as central nervous system agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BG100830A BG100830A (en) | 1997-10-31 |
| BG62887B1 true BG62887B1 (bg) | 2000-10-31 |
Family
ID=22810896
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG100830A BG62887B1 (bg) | 1994-03-24 | 1996-09-05 | Нафтиламиди като средства, повлияващи централната нервна система |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US5395835A (no) |
| EP (1) | EP0751939B9 (no) |
| JP (1) | JP3771581B2 (no) |
| KR (1) | KR100366175B1 (no) |
| AT (1) | ATE219068T1 (no) |
| AU (1) | AU683358B2 (no) |
| BG (1) | BG62887B1 (no) |
| CZ (1) | CZ284377B6 (no) |
| DE (1) | DE69527053T2 (no) |
| DK (1) | DK0751939T5 (no) |
| ES (1) | ES2178668T4 (no) |
| FI (1) | FI113370B (no) |
| HU (1) | HUT76058A (no) |
| MX (1) | MX9602517A (no) |
| NO (1) | NO306779B1 (no) |
| NZ (1) | NZ281824A (no) |
| PH (1) | PH31335A (no) |
| PL (1) | PL181270B1 (no) |
| PT (1) | PT751939E (no) |
| RO (1) | RO117452B1 (no) |
| RU (1) | RU2157370C2 (no) |
| WO (1) | WO1995025727A1 (no) |
| ZA (1) | ZA952382B (no) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4425146A1 (de) * | 1994-07-15 | 1996-01-18 | Basf Ag | Verwendung heterocyclischer Verbindungen |
| DE69618050T2 (de) * | 1995-03-17 | 2002-07-11 | Aventis Pharmaceuticals Inc., Cincinnati | Substituierte Benzylthienylpiperazine, ihre Anwendung als Arzneimittel und Verfahren für ihre Herstellung |
| FR2738569B1 (fr) * | 1995-09-12 | 1997-11-28 | Pf Medicament | Nouveaux derives naphtamide de 3 beta-amino azabicyclo octane ou nonane, leur procede de preparation, leur utilisation a titre de medicament antipsychotique |
| US5659033A (en) * | 1995-09-13 | 1997-08-19 | Neurogen Corporation | N-aminoalkylfluorenecarboxamides; a new class of dopamine receptor subtype specific ligands |
| FR2742149B1 (fr) | 1995-12-11 | 1998-02-13 | Inst Nat Sante Rech Med | Nouveaux derives de 2-naphtamides et leurs applications therapeutiques |
| US5710274A (en) * | 1996-02-28 | 1998-01-20 | Neurogen Corporation | N-aminoalkyldibenzofurancarboxamides; new dopamine receptor subtype specific ligands |
| US5703235A (en) | 1996-03-21 | 1997-12-30 | Neurogen Corporation | N-Aminoalkyl-2-anthracenecarboxamides; new dopamine receptor subtype specific ligands |
| US5763609A (en) * | 1996-03-21 | 1998-06-09 | Neurogen Corporation | Certain pyrrolo pyridine-3-carboxamides; a new class of gaba brain receptor ligands |
| US5703083A (en) * | 1996-04-15 | 1997-12-30 | Neurogen Corporation | N-aminoalkyl-1-biphenylenyl-2-carboxamides; new dopamine receptor subtype specific ligands |
| US5703237A (en) * | 1996-04-18 | 1997-12-30 | Neurogen Corporation | N-Aminoalkyl-2-anthraquinonecarboxamides; new dopamine receptor subtype specific ligands |
| US5688950A (en) * | 1996-04-23 | 1997-11-18 | Neurogen Corporation | Tricyclic aminoalkylcarboxamides; novel dopamine D3 receptor subtype specific ligands |
| US5892041A (en) * | 1996-08-12 | 1999-04-06 | Neurogen Corporation | Fused indolecarboxamides: dopamine receptor subtype specific ligands |
| US6635642B1 (en) | 1997-09-03 | 2003-10-21 | Guilford Pharmaceuticals Inc. | PARP inhibitors, pharmaceutical compositions comprising same, and methods of using same |
| US6197785B1 (en) | 1997-09-03 | 2001-03-06 | Guilford Pharmaceuticals Inc. | Alkoxy-substituted compounds, methods, and compositions for inhibiting PARP activity |
| US6346536B1 (en) | 1997-09-03 | 2002-02-12 | Guilford Pharmaceuticals Inc. | Poly(ADP-ribose) polymerase inhibitors and method for treating neural or cardiovascular tissue damage using the same |
| US6426415B1 (en) | 1997-09-03 | 2002-07-30 | Guilford Pharmaceuticals Inc. | Alkoxy-substituted compounds, methods and compositions for inhibiting parp activity |
| US6291425B1 (en) | 1999-09-01 | 2001-09-18 | Guilford Pharmaceuticals Inc. | Compounds, methods and pharmaceutical compositions for treating cellular damage, such as neural or cardiovascular tissue damage |
| US6514983B1 (en) | 1997-09-03 | 2003-02-04 | Guilford Pharmaceuticals Inc. | Compounds, methods and pharmaceutical compositions for treating neural or cardiovascular tissue damage |
| US6395749B1 (en) | 1998-05-15 | 2002-05-28 | Guilford Pharmaceuticals Inc. | Carboxamide compounds, methods, and compositions for inhibiting PARP activity |
| EP1077944A1 (en) * | 1998-05-15 | 2001-02-28 | Guilford Pharmaceuticals Inc. | Carboxamide compounds, compositions, and methods for inhibiting parp activity |
| US6387902B1 (en) | 1998-12-31 | 2002-05-14 | Guilford Pharmaceuticals, Inc. | Phenazine compounds, methods and pharmaceutical compositions for inhibiting PARP |
| ES2311012T3 (es) * | 2000-03-27 | 2009-02-01 | ABBOTT GMBH & CO. KG | Ligandos del receptor d3 de la dopamina para el tratamiento de la adiccion. |
| US6723733B2 (en) | 2000-05-19 | 2004-04-20 | Guilford Pharmaceuticals, Inc. | Sulfonamide and carbamide derivatives of 6(5H)phenanthridinones and their uses |
| WO2001091796A2 (en) | 2000-06-01 | 2001-12-06 | Guilford Pharmaceuticals Inc. | Methods, compounds and compositions for treating gout |
| WO2002006240A1 (en) | 2000-07-13 | 2002-01-24 | Guilford Pharmaceuticals Inc. | Substituted 4,9-dihydrocyclopenta[imn] phenanthridine-5-ones, derivatives thereof and their uses |
| DE60216753T2 (de) * | 2001-02-16 | 2008-01-03 | Aventis Pharmaceuticals Inc. | Heterocyclische harnstoffderivate und deren verwendung als dopamine d3 receptor liganden |
| EP1688412A3 (en) * | 2001-02-16 | 2006-08-16 | Aventis Pharmaceuticals, Inc. | Novel heterocyclic amide derivatives and their use as dopamine D3 receptor ligands |
| JP2005531571A (ja) * | 2002-05-23 | 2005-10-20 | アボット・ラボラトリーズ | 性機能不全の治療に有用なアセトアミド類およびベンズアミド類 |
| EP1870405A1 (en) * | 2006-06-22 | 2007-12-26 | Bioprojet | Carbonylated (Aza)cyclohexanes as dopamine D3 receptor ligands |
| KR20230001660U (ko) | 2022-02-08 | 2023-08-16 | 주식회사 승진피엘에스 | 옷걸이용 지주 고정장치 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1543944A (fr) * | 1967-03-10 | 1968-10-31 | Bruneau & Cie Lab | Dérivés amidés de l'acide salicylique et leur préparation |
| US3846430A (en) * | 1968-01-12 | 1974-11-05 | Bruneau & Cie Lab | 1-(2-methoxy-phenyl)-4-{8 2-(4-fluoro-benzamido)-ethyl{9 -piperazine |
| US4975439A (en) * | 1987-09-25 | 1990-12-04 | Janssen Pharmaceutical N.V. | Novel substituted N-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides |
| IL90279A (en) * | 1988-05-24 | 1995-03-30 | American Home Prod | History of piperazinyl carboxamide, their preparation and the pharmaceutical preparations containing them |
| US5010078A (en) * | 1988-05-24 | 1991-04-23 | American Home Products Corporation | Aryl- and heteroaryl piperazinyl carboxamides having central nervous system activity |
| JP2671059B2 (ja) * | 1990-11-30 | 1997-10-29 | 富士レビオ株式会社 | ナフトエ酸誘導体 |
| FR2682953B1 (fr) * | 1991-10-23 | 1995-04-21 | Inst Nat Sante Rech Med | Nouveaux derives de naphtamides, leur procede de preparation et leur application dans le domaine therapeutique. |
| SE9201138D0 (sv) * | 1992-04-09 | 1992-04-09 | Astra Ab | Novel phthalimidoalkylpiperazines |
| FR2693722B1 (fr) * | 1992-07-16 | 1994-10-14 | Meram Lab | Dérivés de la N-cycloalkylpipérazine, procédé d'obtention et compositions pharmaceutiques les contenant. |
| GB9218113D0 (en) * | 1992-08-26 | 1992-10-14 | Lilly Industries Ltd | Pharmaceutical compounds |
-
1994
- 1994-03-24 US US08/217,395 patent/US5395835A/en not_active Expired - Fee Related
-
1995
- 1995-02-16 JP JP52463695A patent/JP3771581B2/ja not_active Expired - Fee Related
- 1995-02-16 KR KR1019960705267A patent/KR100366175B1/ko not_active IP Right Cessation
- 1995-02-16 WO PCT/US1995/001974 patent/WO1995025727A1/en active IP Right Grant
- 1995-02-16 DE DE69527053T patent/DE69527053T2/de not_active Expired - Fee Related
- 1995-02-16 NZ NZ281824A patent/NZ281824A/en unknown
- 1995-02-16 DK DK95911021T patent/DK0751939T5/da active
- 1995-02-16 CZ CZ962768A patent/CZ284377B6/cs not_active IP Right Cessation
- 1995-02-16 RO RO96-01853A patent/RO117452B1/ro unknown
- 1995-02-16 MX MX9602517A patent/MX9602517A/es not_active IP Right Cessation
- 1995-02-16 AU AU18774/95A patent/AU683358B2/en not_active Ceased
- 1995-02-16 RU RU96119964/04A patent/RU2157370C2/ru not_active IP Right Cessation
- 1995-02-16 AT AT95911021T patent/ATE219068T1/de not_active IP Right Cessation
- 1995-02-16 HU HU9602605A patent/HUT76058A/hu unknown
- 1995-02-16 EP EP95911021A patent/EP0751939B9/en not_active Expired - Lifetime
- 1995-02-16 PL PL95316313A patent/PL181270B1/pl not_active IP Right Cessation
- 1995-02-16 ES ES95911021T patent/ES2178668T4/es not_active Expired - Lifetime
- 1995-02-16 PT PT95911021T patent/PT751939E/pt unknown
- 1995-03-21 PH PH50161A patent/PH31335A/en unknown
- 1995-03-23 ZA ZA952382A patent/ZA952382B/xx unknown
-
1996
- 1996-08-23 FI FI963294A patent/FI113370B/fi not_active IP Right Cessation
- 1996-09-05 BG BG100830A patent/BG62887B1/bg unknown
- 1996-09-23 NO NO963996A patent/NO306779B1/no not_active IP Right Cessation
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