BG62771B1 - Хетероциклилкарбоксамидни производни, метод за получаването и използването им като терапевтични средства - Google Patents
Хетероциклилкарбоксамидни производни, метод за получаването и използването им като терапевтични средства Download PDFInfo
- Publication number
- BG62771B1 BG62771B1 BG102145A BG10214597A BG62771B1 BG 62771 B1 BG62771 B1 BG 62771B1 BG 102145 A BG102145 A BG 102145A BG 10214597 A BG10214597 A BG 10214597A BG 62771 B1 BG62771 B1 BG 62771B1
- Authority
- BG
- Bulgaria
- Prior art keywords
- methyl
- benzodioxan
- carboxamide
- ylmethyl
- pyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9514380.6A GB9514380D0 (en) | 1995-07-13 | 1995-07-13 | Therapeutic agents |
| PCT/EP1996/002890 WO1997003071A1 (en) | 1995-07-13 | 1996-07-02 | Heterocyclylcarboxamide derivatives and their use as therapeutic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BG102145A BG102145A (en) | 1998-11-30 |
| BG62771B1 true BG62771B1 (bg) | 2000-07-31 |
Family
ID=10777626
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG102145A BG62771B1 (bg) | 1995-07-13 | 1997-12-23 | Хетероциклилкарбоксамидни производни, метод за получаването и използването им като терапевтични средства |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US5935973A (pt) |
| EP (1) | EP0839145B1 (pt) |
| JP (1) | JPH11508599A (pt) |
| KR (1) | KR19990028918A (pt) |
| CN (1) | CN1071755C (pt) |
| AT (1) | ATE253573T1 (pt) |
| AU (1) | AU708890B2 (pt) |
| BG (1) | BG62771B1 (pt) |
| BR (1) | BR9609506A (pt) |
| CA (1) | CA2223472A1 (pt) |
| CZ (1) | CZ388497A3 (pt) |
| DE (1) | DE69630604T2 (pt) |
| GB (1) | GB9514380D0 (pt) |
| HR (1) | HRP960348A2 (pt) |
| HU (1) | HUP9901485A3 (pt) |
| IL (1) | IL122540A (pt) |
| MX (1) | MX9800084A (pt) |
| NO (1) | NO980129D0 (pt) |
| NZ (1) | NZ313164A (pt) |
| PL (1) | PL324529A1 (pt) |
| RU (1) | RU2169147C2 (pt) |
| SK (1) | SK2498A3 (pt) |
| TR (1) | TR199800041T1 (pt) |
| TW (1) | TW454006B (pt) |
| WO (1) | WO1997003071A1 (pt) |
| ZA (1) | ZA965921B (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9811879D0 (en) * | 1998-06-03 | 1998-07-29 | Knoll Ag | Therapeutic agents |
| GB9915616D0 (en) * | 1999-07-05 | 1999-09-01 | Knoll Ag | Therapeutic agents |
| UA73981C2 (en) | 2000-03-10 | 2005-10-17 | Merck Patent Gmbh | (r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane for treatment of extrapyramidal movement disorders (variants), pharmaceutical composition and kit |
| WO2001078648A2 (en) * | 2000-04-17 | 2001-10-25 | Dong Wha Pharm. Ind. Co., Ltd. | 6-methylnicotinamide derivatives as antiviral agents |
| CA2428519A1 (en) * | 2000-11-14 | 2002-05-23 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Novel uses of combined selective dopamine d2 receptor antagonists and 5-ht1a receptor agonists |
| GB0112836D0 (en) | 2001-05-25 | 2001-07-18 | Smithkline Beecham Plc | Medicaments |
| US8106074B2 (en) | 2001-07-13 | 2012-01-31 | Pierre Fabre Medicament | Pyridin-2-yl-methylamine derivatives for treating opiate dependence |
| CN1292749C (zh) | 2001-07-26 | 2007-01-03 | 默克专利股份有限公司 | 2－[5－(4－氟苯基)－3－吡啶基甲氨基甲基]苯并二氢吡喃及其生理学上可接受的盐的新用途 |
| KR101204247B1 (ko) | 2003-07-22 | 2012-11-22 | 아스텍스 테라퓨틱스 리미티드 | 3,4-이치환된 1ｈ-피라졸 화합물 및 그의 시클린 의존성키나제 (ｃｄｋ) 및 글리코겐 합성효소 키나제-3(ｇｓｋ-3) 조정제로서 용도 |
| WO2005080394A1 (en) * | 2004-02-24 | 2005-09-01 | Bioaxone Therapeutique Inc. | 4-substituted piperidine derivatives |
| JP4604583B2 (ja) * | 2004-07-20 | 2011-01-05 | ダイソー株式会社 | １−アミド−３−（２−ヒドロキシフェノキシ）−２−プロパノール誘導体、ならびに２−アミドメチル−１，４−ベンゾジオキサン誘導体の製造法 |
| WO2006077424A1 (en) | 2005-01-21 | 2006-07-27 | Astex Therapeutics Limited | Pharmaceutical compounds |
| JP5475235B2 (ja) | 2005-01-21 | 2014-04-16 | アステックス・セラピューティクス・リミテッド | 医薬化合物 |
| TWI457122B (zh) | 2007-07-20 | 2014-10-21 | Orion Corp | 作為用於治療周邊和中央神經系統疾病之alpha2C拮抗劑的2,3－二氫苯並[1,4]戴奧辛－2－基甲基衍生物 |
| AU2009242092A1 (en) * | 2008-04-29 | 2009-11-05 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | Modulators of dopamine neurotransmission |
| MX356699B (es) * | 2012-06-11 | 2018-06-11 | Bristol Myers Squibb Co | Profarmacos de acido fosforamidico de 5-[5-fenil-4-(piridin-2-ilme tilamino) quinazolin-2-il]piridin-3-sulfonamida. |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8302622D0 (en) * | 1983-01-31 | 1983-03-02 | Celltech Ltd | Immunoassay |
| EP0200960A1 (en) * | 1985-05-08 | 1986-11-12 | Abbott Laboratories | Total estriol fluorescence polarization immunoassay |
| WO1991013872A1 (en) * | 1990-03-15 | 1991-09-19 | The Upjohn Company | Therapeutically useful heterocyclic indole compounds |
| US5240943A (en) * | 1991-12-19 | 1993-08-31 | G. D. Searle & Co. | Benzopyran class iii antiarrhythmic agents |
| GB9314758D0 (en) * | 1993-07-16 | 1993-08-25 | Wyeth John & Brother Ltd | Heterocyclic derivatives |
| GB9318431D0 (en) * | 1993-09-06 | 1993-10-20 | Boots Co Plc | Therapeutic agents |
| FR2724383B1 (fr) * | 1994-09-13 | 1996-10-18 | Synthelabo | Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique |
-
1995
- 1995-07-13 GB GBGB9514380.6A patent/GB9514380D0/en active Pending
-
1996
- 1996-07-02 SK SK24-98A patent/SK2498A3/sk unknown
- 1996-07-02 CZ CZ973884A patent/CZ388497A3/cs unknown
- 1996-07-02 IL IL12254096A patent/IL122540A/en not_active IP Right Cessation
- 1996-07-02 US US08/981,671 patent/US5935973A/en not_active Expired - Lifetime
- 1996-07-02 NZ NZ313164A patent/NZ313164A/xx unknown
- 1996-07-02 CN CN96195477A patent/CN1071755C/zh not_active Expired - Fee Related
- 1996-07-02 DE DE69630604T patent/DE69630604T2/de not_active Expired - Fee Related
- 1996-07-02 CA CA002223472A patent/CA2223472A1/en not_active Abandoned
- 1996-07-02 MX MX9800084A patent/MX9800084A/es not_active Application Discontinuation
- 1996-07-02 AU AU65172/96A patent/AU708890B2/en not_active Ceased
- 1996-07-02 AT AT96924847T patent/ATE253573T1/de not_active IP Right Cessation
- 1996-07-02 RU RU98102441/04A patent/RU2169147C2/ru active
- 1996-07-02 WO PCT/EP1996/002890 patent/WO1997003071A1/en not_active Application Discontinuation
- 1996-07-02 TR TR1998/00041T patent/TR199800041T1/xx unknown
- 1996-07-02 PL PL96324529A patent/PL324529A1/xx unknown
- 1996-07-02 JP JP9505471A patent/JPH11508599A/ja not_active Withdrawn
- 1996-07-02 BR BR9609506A patent/BR9609506A/pt unknown
- 1996-07-02 KR KR1019980700220A patent/KR19990028918A/ko not_active Application Discontinuation
- 1996-07-02 HU HU9901485A patent/HUP9901485A3/hu unknown
- 1996-07-02 EP EP96924847A patent/EP0839145B1/en not_active Expired - Lifetime
- 1996-07-12 HR HR9514380.6A patent/HRP960348A2/hr not_active Application Discontinuation
- 1996-07-12 ZA ZA9605921A patent/ZA965921B/xx unknown
- 1996-12-19 TW TW085115692A patent/TW454006B/zh not_active IP Right Cessation
-
1997
- 1997-12-23 BG BG102145A patent/BG62771B1/bg unknown
-
1998
- 1998-01-12 NO NO980129A patent/NO980129D0/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ313164A (en) | 1999-07-29 |
| HUP9901485A2 (en) | 2000-07-28 |
| HUP9901485A3 (en) | 2001-03-28 |
| EP0839145A1 (en) | 1998-05-06 |
| HRP960348A2 (en) | 1998-04-30 |
| IL122540A0 (en) | 1998-06-15 |
| IL122540A (en) | 2001-10-31 |
| US5935973A (en) | 1999-08-10 |
| CN1071755C (zh) | 2001-09-26 |
| TR199800041T1 (xx) | 1998-05-21 |
| DE69630604T2 (de) | 2004-09-23 |
| WO1997003071A1 (en) | 1997-01-30 |
| AU708890B2 (en) | 1999-08-12 |
| MX9800084A (es) | 1998-03-29 |
| CA2223472A1 (en) | 1997-01-30 |
| RU2169147C2 (ru) | 2001-06-20 |
| CZ388497A3 (cs) | 1998-06-17 |
| CN1190967A (zh) | 1998-08-19 |
| BR9609506A (pt) | 1999-06-01 |
| NO980129L (no) | 1998-01-12 |
| GB9514380D0 (en) | 1995-09-13 |
| ZA965921B (en) | 1998-01-12 |
| TW454006B (en) | 2001-09-11 |
| BG102145A (en) | 1998-11-30 |
| SK2498A3 (en) | 1998-09-09 |
| KR19990028918A (ko) | 1999-04-15 |
| NO980129D0 (no) | 1998-01-12 |
| EP0839145B1 (en) | 2003-11-05 |
| ATE253573T1 (de) | 2003-11-15 |
| JPH11508599A (ja) | 1999-07-27 |
| AU6517296A (en) | 1997-02-10 |
| PL324529A1 (en) | 1998-06-08 |
| DE69630604D1 (de) | 2003-12-11 |
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