BG62167B1 - Производни на аскорбинова киселина,методи за тяхното получаване и приложение - Google Patents

Производни на аскорбинова киселина,методи за тяхното получаване и приложение Download PDF

Info

Publication number
BG62167B1
BG62167B1 BG98438A BG9843894A BG62167B1 BG 62167 B1 BG62167 B1 BG 62167B1 BG 98438 A BG98438 A BG 98438A BG 9843894 A BG9843894 A BG 9843894A BG 62167 B1 BG62167 B1 BG 62167B1
Authority
BG
Bulgaria
Prior art keywords
group
ascorbic acid
general formula
formula
compounds
Prior art date
Application number
BG98438A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG98438A (bg
Inventor
Bozidar Suskovic
Vanja Vela
Mira Buncic
Original Assignee
Pliva Farmaceutska,Kemijska,Prehrambena Ikozmeticka Industrija, Dionicko Drustvo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Farmaceutska,Kemijska,Prehrambena Ikozmeticka Industrija, Dionicko Drustvo filed Critical Pliva Farmaceutska,Kemijska,Prehrambena Ikozmeticka Industrija, Dionicko Drustvo
Publication of BG98438A publication Critical patent/BG98438A/bg
Publication of BG62167B1 publication Critical patent/BG62167B1/bg

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/62Three oxygen atoms, e.g. ascorbic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/66Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)
  • Furan Compounds (AREA)
BG98438A 1993-02-05 1994-02-04 Производни на аскорбинова киселина,методи за тяхното получаване и приложение BG62167B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HR930131A HRP930131A2 (en) 1993-02-05 1993-02-05 Amino-ascorbic acid derivatives, process for the preparation and use thereof
JP6013667A JPH07101950A (ja) 1993-02-05 1994-02-07 アミノ−アスコルビン酸誘導体、その製造法及び用途

Publications (2)

Publication Number Publication Date
BG98438A BG98438A (bg) 1994-09-30
BG62167B1 true BG62167B1 (bg) 1999-04-30

Family

ID=26316867

Family Applications (1)

Application Number Title Priority Date Filing Date
BG98438A BG62167B1 (bg) 1993-02-05 1994-02-04 Производни на аскорбинова киселина,методи за тяхното получаване и приложение

Country Status (11)

Country Link
EP (3) EP0609899A1 (zh)
JP (1) JPH07101950A (zh)
CN (1) CN1099753A (zh)
BG (1) BG62167B1 (zh)
CA (1) CA2114970C (zh)
CZ (1) CZ24594A3 (zh)
HR (1) HRP930131A2 (zh)
HU (1) HUT71606A (zh)
PL (1) PL302144A1 (zh)
SI (1) SI9400061A (zh)
SK (1) SK12894A3 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4980911B2 (ja) 2005-01-25 2012-07-18 パナソニック株式会社 電源システム
KR101119027B1 (ko) * 2009-05-07 2012-03-14 (주)코스몰 아스코르빈산 유도체의 제조방법
JP2013230984A (ja) * 2010-08-19 2013-11-14 Seiwa Kasei Co Ltd アスコルビン酸由来組成物、その製造方法、及び化粧料
JP6872548B2 (ja) 2015-12-03 2021-05-19 スリーエム イノベイティブ プロパティズ カンパニー 光解離性還元剤を有するレドックス重合性組成物
CN118480032A (zh) * 2021-04-30 2024-08-13 禾美生物科技(浙江)有限公司 抗坏血酸多肽衍生物及其制备方法和应用
CN114369075B (zh) * 2022-02-14 2023-09-29 河北乐开节能科技股份有限公司 利用2-酮基-l-古龙酸的水溶液一步制备vc结晶的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2616351A1 (de) * 1975-05-03 1976-11-11 Hoffmann La Roche Halogenderivate
US4440738A (en) * 1982-06-10 1984-04-03 Mallinckrodt, Inc. Stable radiographic imaging agents
US4504462A (en) * 1982-06-10 1985-03-12 Mallinckrodt, Inc. Process for making a lyophilized product for use in skeletal imaging
EP0446539A1 (en) * 1990-03-16 1991-09-18 Merrell Dow Pharmaceuticals Inc. Novel ascorbic acid derivatives

Also Published As

Publication number Publication date
CN1099753A (zh) 1995-03-08
HUT71606A (en) 1996-01-29
CA2114970A1 (en) 1994-08-06
HRP930131A2 (en) 1997-02-28
CZ24594A3 (en) 1994-08-17
BG98438A (bg) 1994-09-30
EP0791588A1 (en) 1997-08-27
SI9400061A (en) 1994-09-30
CA2114970C (en) 1999-06-22
SK12894A3 (en) 1994-12-07
HU9400325D0 (en) 1994-05-30
EP0609899A1 (en) 1994-08-10
JPH07101950A (ja) 1995-04-18
EP0791587A1 (en) 1997-08-27
PL302144A1 (en) 1994-08-08

Similar Documents

Publication Publication Date Title
Gibson et al. Selective removal of an N-BOC protecting group in the presence of a tert-butyl ester and other acid-sensitive groups
Nishizawa et al. Synthesis and structure-activity relations of bestatin analogs, inhibitors of aminopeptidase B
DK170750B1 (da) Vandopløselige, farmaceutisk acceptable salte af i 43-stillingen monosubstitueret rapamycin, fremgangsmåde til fremstilling heraf og injicerbare, farmaceutiske præparater indeholdende et sådant salt.
Greenberg et al. Structure and dynamics of Troeger's base and simple derivatives in acidic media
BG60999B1 (en) Method for the preparation of clavulanic acid
NL8202626A (nl) Derivaten van 9-(2-hydroxyethoxymethyl)guanine.
Khomutov et al. Synthesis of hydroxylamine analogues of polyamines
Georg et al. Asymmetric synthesis of α-alkylated α-amino acids via Schmidt rearrangement of α, α-bisalkylated β-keto esters
BG62167B1 (bg) Производни на аскорбинова киселина,методи за тяхното получаване и приложение
Iyengar et al. Preparation and antitumor activity of 7-substituted 1, 2-aziridinomitosenes
Sauer et al. Memory effect of chirality in the photocyclization of modified dipeptides
EP0081726B1 (en) Nitrobenzoic acid amide derivatives
Granier et al. First unequivocal synthesis of 1 or 8-N-monosubstituted 1, 4, 8, 12-tetraazacyclopentadecane
Wagenaar et al. Methodology for the preparation of N-guanidino-modified arginines and related derivatives
Fikes et al. Preassociating. alpha.-nucleophiles
US5610181A (en) Derivatives of amino-ascorbic acid, the processes for their preparation and use
RU2126398C1 (ru) Производные аминоаскорбиновой кислоты, способы их получения и производные галоидаскорбиновой кислоты
Wadher et al. Synthesis and biological evaluation of Schiff bases of Cinchophen as antimicrobial agents
DK161833B (da) Analogifremgangsmaade til fremstilling af n-(vinblastinoyl-23)-derivater af aminosyrer eller farmaceutisk acceptable syreadditionssalte deraf
Rosowsky et al. Analogs of methotrexate and aminopterin with. gamma.-methylene and. gamma.-cyano substitution of the glutamate side chain: synthesis and in vitro biological activity. 40
CN105566447A (zh) 一种凋亡抑制蛋白的类肽拮抗剂及其合成方法与应用
BG62520B1 (bg) Аналози на аргинина, притежаващи инхибираща активност върхуno-синтетазата
Thanassi Reaction of diaminomaleonitrile with acetaldehyde
CN109928916A (zh) 一类作为ido抑制剂的喹啉-4-基环己烷类化合物
CN118005716B (zh) 一种细胞毒素衍生物及制备方法与应用