BG61593B1 - Имидазолилалкенови киселини - Google Patents

Имидазолилалкенови киселини Download PDF

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Publication number
BG61593B1
BG61593B1 BG98454A BG9845494A BG61593B1 BG 61593 B1 BG61593 B1 BG 61593B1 BG 98454 A BG98454 A BG 98454A BG 9845494 A BG9845494 A BG 9845494A BG 61593 B1 BG61593 B1 BG 61593B1
Authority
BG
Bulgaria
Prior art keywords
methyl
butyl
imidazol
thienyl
compound
Prior art date
Application number
BG98454A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG98454A (bg
Inventor
Richard M. Keenan
Joseph Weinstock
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of BG98454A publication Critical patent/BG98454A/bg
Publication of BG61593B1 publication Critical patent/BG61593B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BG98454A 1991-08-14 1994-02-11 Имидазолилалкенови киселини BG61593B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/746,262 US5185351A (en) 1989-06-14 1991-08-14 Imidazolyl-alkenoic acids useful as angiotensin II receptor antagonists
PCT/US1992/006734 WO1993003722A1 (en) 1991-08-14 1992-08-12 Imidazolyl-alkenoic acids

Publications (2)

Publication Number Publication Date
BG98454A BG98454A (bg) 1995-02-28
BG61593B1 true BG61593B1 (bg) 1998-01-30

Family

ID=25000103

Family Applications (1)

Application Number Title Priority Date Filing Date
BG98454A BG61593B1 (bg) 1991-08-14 1994-02-11 Имидазолилалкенови киселини

Country Status (32)

Country Link
US (1) US5185351A (enExample)
EP (1) EP0641203B1 (enExample)
JP (1) JPH07500579A (enExample)
CN (1) CN1036396C (enExample)
AP (3) AP525A (enExample)
AT (1) ATE226073T1 (enExample)
AU (1) AU667824B2 (enExample)
BG (1) BG61593B1 (enExample)
BR (1) BR9206443A (enExample)
CA (1) CA2115170C (enExample)
CZ (1) CZ281635B6 (enExample)
DE (1) DE69232817T2 (enExample)
DK (1) DK0641203T3 (enExample)
ES (1) ES2185617T3 (enExample)
FI (1) FI114796B (enExample)
HU (1) HU225048B1 (enExample)
IL (1) IL102813A (enExample)
MA (1) MA22626A1 (enExample)
MX (1) MX9204737A (enExample)
MY (1) MY110205A (enExample)
NO (1) NO305172B1 (enExample)
NZ (1) NZ243966A (enExample)
OA (1) OA09884A (enExample)
PL (1) PL177234B1 (enExample)
PT (1) PT100779B (enExample)
RO (1) RO113643B1 (enExample)
RU (1) RU2124513C1 (enExample)
SK (1) SK281252B6 (enExample)
TW (1) TW234690B (enExample)
UA (1) UA40587C2 (enExample)
WO (1) WO1993003722A1 (enExample)
ZA (1) ZA926133B (enExample)

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* Cited by examiner, † Cited by third party
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US6025380A (en) * 1990-12-14 2000-02-15 Smithkline Beecham Plc Medicament
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US6034114A (en) * 1990-12-14 2000-03-07 Smithkline Beecham Plc Medicament
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DK0565634T3 (da) * 1990-12-14 1999-09-27 Smithkline Beecham Corp Angiotensin-II-receptorblokkersammensætninger
GB9027208D0 (en) * 1990-12-14 1991-02-06 Smithkline Beecham Plc Medicaments
GB9027199D0 (en) * 1990-12-14 1991-02-06 Smithkline Beecham Plc Medicaments

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AU667824B2 (en) 1996-04-18
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CN1036396C (zh) 1997-11-12
EP0641203B1 (en) 2002-10-16
CA2115170C (en) 2004-05-25
JPH07500579A (ja) 1995-01-19
CZ281635B6 (cs) 1996-11-13
AP526A (en) 1996-09-06
MY110205A (en) 1998-02-28
TW234690B (enExample) 1994-11-21
AP527A (en) 1996-09-06
HU9400413D0 (en) 1994-05-30
NZ243966A (en) 1996-08-27
WO1993003722A1 (en) 1993-03-04
DE69232817D1 (de) 2002-11-21
CA2115170A1 (en) 1993-03-04
ZA926133B (en) 1993-03-31
NO940476L (no) 1994-04-11
AP9200416A0 (en) 1992-10-31
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EP0641203A1 (en) 1995-03-08
BR9206443A (pt) 1994-09-27
HUT70157A (en) 1995-09-28
FI940642A0 (fi) 1994-02-11
AP9500741A0 (en) 1995-07-31
RO113643B1 (ro) 1998-09-30
MX9204737A (es) 1994-02-28
US5185351A (en) 1993-02-09
RU2124513C1 (ru) 1999-01-10
IL102813A0 (en) 1993-01-31
CZ31194A3 (en) 1994-12-15
IL102813A (en) 1999-07-14
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AU2475692A (en) 1993-03-16
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AP9500742A0 (en) 1995-07-31
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OA09884A (en) 1994-09-15
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