BG61277B1 - Process for the preparation of optically activecyanohydrines with enzymes - Google Patents

Process for the preparation of optically activecyanohydrines with enzymes Download PDF

Info

Publication number
BG61277B1
BG61277B1 BG97619A BG9761993A BG61277B1 BG 61277 B1 BG61277 B1 BG 61277B1 BG 97619 A BG97619 A BG 97619A BG 9761993 A BG9761993 A BG 9761993A BG 61277 B1 BG61277 B1 BG 61277B1
Authority
BG
Bulgaria
Prior art keywords
membrane
enzyme
aldehyde
porous membrane
binder
Prior art date
Application number
BG97619A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG97619A (bg
Inventor
Stephen W Andruski
Bruce Goldberg
Original Assignee
Fmc Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fmc Corp filed Critical Fmc Corp
Publication of BG97619A publication Critical patent/BG97619A/bg
Publication of BG61277B1 publication Critical patent/BG61277B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/002—Nitriles (-CN)
    • C12P13/004—Cyanohydrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BG97619A 1991-12-17 1993-04-07 Process for the preparation of optically activecyanohydrines with enzymes BG61277B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/809,803 US5177242A (en) 1991-12-17 1991-12-17 Process for preparing optically active cyanohydrins with enzymes
PCT/US1992/009945 WO1993012072A1 (fr) 1991-12-17 1992-11-13 Procede de preparation de cyanohydrines optiquement actives avec des enzymes

Publications (2)

Publication Number Publication Date
BG97619A BG97619A (bg) 1994-03-31
BG61277B1 true BG61277B1 (en) 1997-04-30

Family

ID=25202264

Family Applications (1)

Application Number Title Priority Date Filing Date
BG97619A BG61277B1 (en) 1991-12-17 1993-04-07 Process for the preparation of optically activecyanohydrines with enzymes

Country Status (25)

Country Link
US (1) US5177242A (fr)
EP (1) EP0590096B1 (fr)
JP (2) JPH0832243B2 (fr)
KR (1) KR970009155B1 (fr)
CN (1) CN1075166A (fr)
AR (1) AR247921A1 (fr)
AT (1) ATE135047T1 (fr)
AU (1) AU647982B2 (fr)
BG (1) BG61277B1 (fr)
BR (1) BR9205413A (fr)
CA (1) CA2093826C (fr)
CZ (1) CZ280422B6 (fr)
DE (2) DE69208878T2 (fr)
FI (1) FI931583A (fr)
HU (1) HUT71308A (fr)
IL (1) IL104046A0 (fr)
MW (1) MW4993A1 (fr)
MX (1) MX9206954A (fr)
OA (1) OA09873A (fr)
PL (1) PL170490B1 (fr)
RO (1) RO112765B1 (fr)
RU (1) RU2092558C1 (fr)
SK (1) SK36293A3 (fr)
TW (1) TW242166B (fr)
WO (1) WO1993012072A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT396252B (de) * 1991-10-31 1993-07-26 Chemie Linz Gmbh Enzymatisches verfahren zur enantioselektiven herstellung optisch aktiver cyanhydrine
GB9222253D0 (en) * 1992-10-23 1992-12-09 Celltech Ltd Chemical compounds
AT400035B (de) * 1993-06-01 1995-09-25 Chemie Linz Gmbh Enzymatisches verfahren zur herstellung aliphatischer s-cyanhydrine
DE4322064A1 (de) * 1993-07-02 1995-01-12 Chemie Linz Deutschland Enzymatisches Verfahren zur Herstellung aliphatischer S-Cyanhydrine
DE19529116A1 (de) * 1995-08-08 1997-03-06 Chemie Linz Deutschland Gmbh I (S)-Hydroxynitrillyase aus Hevea brasiliensis
DE59711628D1 (de) * 1996-02-09 2004-06-24 Degussa Verfahren zur Herstellung von (S)-Cyanhydrinen
CN1093531C (zh) * 1998-05-04 2002-10-30 中国科学院上海有机化学研究所 氰醇裂解酶催化合成光学活性氰醇化合物
CN1083009C (zh) * 1999-07-16 2002-04-17 中国科学院上海有机化学研究所 一种新酶源的醇腈裂解酶催化合成光学活性氰醇化合物的方法
EP1232277B1 (fr) * 1999-11-25 2003-05-28 Degussa AG Procede de production de cyanhydrines optiquement actives
JP3709317B2 (ja) 2000-01-12 2005-10-26 株式会社日本触媒 光学活性シアノヒドリンの合成方法
US7078225B2 (en) * 2000-06-02 2006-07-18 Nippon Shokubai Co., Ltd. Method for enzymatically producing an optically active cyanohydrin
WO2007026623A1 (fr) * 2005-08-30 2007-03-08 Sumitomo Chemical Company, Limited Procédé de production de 3-amino-6-chloropyridazine

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862030A (en) * 1972-12-13 1975-01-21 Amerace Esna Corp Microporous sub-micron filter media
IL46178A (en) * 1974-12-03 1978-10-31 Rehovot Res Prod Method for the performance of enzymatic reactions
US4102746A (en) * 1975-08-29 1978-07-25 Amerace Corporation Immobilized proteins
US4169014A (en) * 1976-08-16 1979-09-25 Amerace Corporation Method of immobilizing proteinaceous substances
US4795704A (en) * 1985-10-11 1989-01-03 Sepracor, Inc. Multiphase asymmetric membrane reactor systems
US4959467A (en) * 1985-11-27 1990-09-25 Allied-Signal Inc. Control of product selectivity in the addition of HCN to arabinose
US4900667A (en) * 1985-12-19 1990-02-13 Allied-Signal Inc. One carbon homologation of carbohydrates by transcyanohydrination
DE3701383A1 (de) * 1987-01-20 1988-07-28 Degussa Verfahren zur herstellung von optisch aktiven cyanhydrinen
US4800162A (en) * 1987-04-01 1989-01-24 Sepracor, Inc. Method for resolution of steroisomers in multiphase and extractive membrane reactors
DE3823864A1 (de) * 1988-01-29 1989-08-10 Kernforschungsanlage Juelich Enymatisches verfahren zur herstellung von optisch aktiven cyanhydrinen
DE3917374A1 (de) * 1988-07-14 1990-12-06 Forschungszentrum Juelich Gmbh Verfahren zur herstellung von s-cyanhydrinen
EP0446826B1 (fr) * 1990-03-16 1995-11-15 Forschungszentrum Jülich Gmbh Procédé pour la préparation enzymatique de cyannydrine optiquement active
AT396252B (de) * 1991-10-31 1993-07-26 Chemie Linz Gmbh Enzymatisches verfahren zur enantioselektiven herstellung optisch aktiver cyanhydrine

Also Published As

Publication number Publication date
EP0590096B1 (fr) 1996-03-06
MX9206954A (es) 1993-06-01
DE590096T1 (de) 1994-07-28
EP0590096A1 (fr) 1994-04-06
SK36293A3 (en) 1993-10-06
RO112765B1 (ro) 1997-12-30
EP0590096A4 (fr) 1994-02-18
AU3141493A (en) 1993-07-19
CA2093826A1 (fr) 1993-06-18
DE69208878D1 (de) 1996-04-11
AU647982B2 (en) 1994-03-31
ATE135047T1 (de) 1996-03-15
IL104046A0 (en) 1993-05-13
CA2093826C (fr) 1995-08-29
BR9205413A (pt) 1994-05-31
JPH05507736A (ja) 1993-11-04
JPH06506674A (ja) 1994-07-28
AR247921A1 (es) 1995-04-28
WO1993012072A1 (fr) 1993-06-24
HU9301020D0 (en) 1993-11-29
HUT71308A (en) 1995-11-28
CN1075166A (zh) 1993-08-11
CZ65193A3 (en) 1994-04-13
BG97619A (bg) 1994-03-31
RU2092558C1 (ru) 1997-10-10
CZ280422B6 (cs) 1996-01-17
KR970009155B1 (ko) 1997-06-07
FI931583A (fi) 1993-06-18
DE69208878T2 (de) 1996-10-31
JPH0832243B2 (ja) 1996-03-29
MW4993A1 (en) 1994-10-12
TW242166B (fr) 1995-03-01
US5177242A (en) 1993-01-05
PL170490B1 (pl) 1996-12-31
OA09873A (en) 1994-09-15
FI931583A0 (fi) 1993-04-07

Similar Documents

Publication Publication Date Title
Yoshikawa et al. Molecularly imprinted membranes: past, present, and future
US4102746A (en) Immobilized proteins
US4169014A (en) Method of immobilizing proteinaceous substances
BG61277B1 (en) Process for the preparation of optically activecyanohydrines with enzymes
CA2121747C (fr) Polymere hydrophile recouvert de matrices a base de polymere d'hydrocarbure perfluore, leur preparation et leur utilisation dans les travaux de bioaffinite
CN109772178B (zh) 一种基于点击化学双面负载的乙胺嘧啶分子印迹复合膜的制备方法及应用
US4705753A (en) Biologically active acrylonitrile-based copolymeric membrane
Ingole et al. Methods for separation of organic and pharmaceutical compounds by different polymer materials
FR2534486A1 (fr) Support particulaire greffe en surface, son procede de preparation et adsorbants pour chromatographie d'affinite incorporant ce support, ainsi que leur utilisation, notamment en biologie
JPH0458311B2 (fr)
JP3151331B2 (ja) 生化学物質の固定化方法
JPH0616699A (ja) 生化学物質の固定化方法
JP3441530B2 (ja) 温度応答型分離材料及びその製造方法
JP3441496B2 (ja) アフィニティー分離材料
JPS5853922B2 (ja) 加水分解用触媒膜
Kawai et al. Immobilization of ascorbic acid oxydase in multilayers onto porous hollow-fiber membrane
CN110841602B (zh) 基于贻贝仿生化学的血液净化材料及其制备方法
SU755296A1 (ru) Способ получения активированных носителей для иммобилизации биологически активных веществ 1
Wulff Imprinting techniques in synthetic polymers—new options for chemosensors
JPH06256434A (ja) 多孔体、多孔体からなる多孔性担体、多孔性担体を用いた固定化機能性物質、これらの製造方法および多孔体製造用組成物
JPS6254127B2 (fr)
JPH08319431A (ja) スーパー抗原吸着材料
Pişkin Structural and transport properties of polymeric carriers for bioagents and immobilization techniques and their applications