AR247921A1 - Un proceso para la preparacion de (s)cianohidrinas opticamente activas. - Google Patents

Un proceso para la preparacion de (s)cianohidrinas opticamente activas.

Info

Publication number
AR247921A1
AR247921A1 AR92323883A AR32388392A AR247921A1 AR 247921 A1 AR247921 A1 AR 247921A1 AR 92323883 A AR92323883 A AR 92323883A AR 32388392 A AR32388392 A AR 32388392A AR 247921 A1 AR247921 A1 AR 247921A1
Authority
AR
Argentina
Prior art keywords
optically active
porous membrane
enzymes
aldehyde
acid
Prior art date
Application number
AR92323883A
Other languages
English (en)
Original Assignee
Fmc Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fmc Corp filed Critical Fmc Corp
Application granted granted Critical
Publication of AR247921A1 publication Critical patent/AR247921A1/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/002—Nitriles (-CN)
    • C12P13/004—Cyanohydrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PREPARACION DE (S)-CIANOHIDRINAS OPTICAMENTE ACTIVAS POR LA REACCION DE UN ALDEHIDO CON ACIDO HIDROCIANICO A TRAVES DE LA PUESTA EN CONTACTO DE UN SOLVENTE ORGANICO QUE CONTIENE AL ACIDO Y ALDEHIDO CON LA ENZIMA S- OXINITRILASA, Y EN DONDE LA ENZIMA ESTA UNIDA QUIMICAMENTE A UN SUSTRATO INSOLUBLE, QUE COMPRENDE A UNA MEMBRANA POROSA A TRAVES DE LA CUAL SE HACE PASAR A LOS REACTANTES; ESTA MEMBRANA POROSA ESTA FORMADA POR UN ENLAZANTE RESINOSO POLIMERICO QUE TIENE PARTICULAS DE RELLENO O CARGA FINAMENTE DIVIDIDAS DISPERSAS EN SU ESTRUCTURA Y UNA TRAMA DE POROS INTERCONECTADOS DENTRO DE ELLA; SIENDO LA MEMBRANA POROSA PERMEABLE AL FLUJO DE UN FLUIDO CON LOS REACTIVOS MENCIONADOS.
AR92323883A 1991-12-17 1992-12-11 Un proceso para la preparacion de (s)cianohidrinas opticamente activas. AR247921A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/809,803 US5177242A (en) 1991-12-17 1991-12-17 Process for preparing optically active cyanohydrins with enzymes

Publications (1)

Publication Number Publication Date
AR247921A1 true AR247921A1 (es) 1995-04-28

Family

ID=25202264

Family Applications (1)

Application Number Title Priority Date Filing Date
AR92323883A AR247921A1 (es) 1991-12-17 1992-12-11 Un proceso para la preparacion de (s)cianohidrinas opticamente activas.

Country Status (25)

Country Link
US (1) US5177242A (es)
EP (1) EP0590096B1 (es)
JP (2) JPH05507736A (es)
KR (1) KR970009155B1 (es)
CN (1) CN1075166A (es)
AR (1) AR247921A1 (es)
AT (1) ATE135047T1 (es)
AU (1) AU647982B2 (es)
BG (1) BG61277B1 (es)
BR (1) BR9205413A (es)
CA (1) CA2093826C (es)
CZ (1) CZ280422B6 (es)
DE (2) DE590096T1 (es)
FI (1) FI931583A (es)
HU (1) HUT71308A (es)
IL (1) IL104046A0 (es)
MW (1) MW4993A1 (es)
MX (1) MX9206954A (es)
OA (1) OA09873A (es)
PL (1) PL170490B1 (es)
RO (1) RO112765B1 (es)
RU (1) RU2092558C1 (es)
SK (1) SK36293A3 (es)
TW (1) TW242166B (es)
WO (1) WO1993012072A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT396252B (de) * 1991-10-31 1993-07-26 Chemie Linz Gmbh Enzymatisches verfahren zur enantioselektiven herstellung optisch aktiver cyanhydrine
GB9222253D0 (en) * 1992-10-23 1992-12-09 Celltech Ltd Chemical compounds
AT400035B (de) * 1993-06-01 1995-09-25 Chemie Linz Gmbh Enzymatisches verfahren zur herstellung aliphatischer s-cyanhydrine
DE4322064A1 (de) * 1993-07-02 1995-01-12 Chemie Linz Deutschland Enzymatisches Verfahren zur Herstellung aliphatischer S-Cyanhydrine
DE19529116A1 (de) * 1995-08-08 1997-03-06 Chemie Linz Deutschland Gmbh I (S)-Hydroxynitrillyase aus Hevea brasiliensis
DE19703314A1 (de) * 1996-02-09 1997-08-14 Degussa Verfahren zur Herstellung von (S)-Cyanhydrinen
CN1093531C (zh) * 1998-05-04 2002-10-30 中国科学院上海有机化学研究所 氰醇裂解酶催化合成光学活性氰醇化合物
CN1083009C (zh) * 1999-07-16 2002-04-17 中国科学院上海有机化学研究所 一种新酶源的醇腈裂解酶催化合成光学活性氰醇化合物的方法
WO2001038554A2 (de) * 1999-11-25 2001-05-31 Degussa Ag Verfahren zur herstellung von optisch aktiven cyanhydrinen
JP3709317B2 (ja) * 2000-01-12 2005-10-26 株式会社日本触媒 光学活性シアノヒドリンの合成方法
US7078225B2 (en) * 2000-06-02 2006-07-18 Nippon Shokubai Co., Ltd. Method for enzymatically producing an optically active cyanohydrin
WO2007026623A1 (ja) * 2005-08-30 2007-03-08 Sumitomo Chemical Company, Limited ３−アミノ−６−クロロピリダジンの製造方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862030A (en) * 1972-12-13 1975-01-21 Amerace Esna Corp Microporous sub-micron filter media
IL46178A (en) * 1974-12-03 1978-10-31 Rehovot Res Prod Method for the performance of enzymatic reactions
US4102746A (en) * 1975-08-29 1978-07-25 Amerace Corporation Immobilized proteins
US4169014A (en) * 1976-08-16 1979-09-25 Amerace Corporation Method of immobilizing proteinaceous substances
US4795704A (en) * 1985-10-11 1989-01-03 Sepracor, Inc. Multiphase asymmetric membrane reactor systems
US4959467A (en) * 1985-11-27 1990-09-25 Allied-Signal Inc. Control of product selectivity in the addition of HCN to arabinose
US4900667A (en) * 1985-12-19 1990-02-13 Allied-Signal Inc. One carbon homologation of carbohydrates by transcyanohydrination
DE3701383A1 (de) * 1987-01-20 1988-07-28 Degussa Verfahren zur herstellung von optisch aktiven cyanhydrinen
US4800162A (en) * 1987-04-01 1989-01-24 Sepracor, Inc. Method for resolution of steroisomers in multiphase and extractive membrane reactors
DE3823864A1 (de) * 1988-01-29 1989-08-10 Kernforschungsanlage Juelich Enymatisches verfahren zur herstellung von optisch aktiven cyanhydrinen
DE3917374A1 (de) * 1988-07-14 1990-12-06 Forschungszentrum Juelich Gmbh Verfahren zur herstellung von s-cyanhydrinen
DE59106876D1 (de) * 1990-03-16 1995-12-21 Forschungszentrum Juelich Gmbh Verfahren zur enzymatischen Herstellung optisch aktiver Cyanhydrine.
AT396252B (de) * 1991-10-31 1993-07-26 Chemie Linz Gmbh Enzymatisches verfahren zur enantioselektiven herstellung optisch aktiver cyanhydrine

Also Published As

Publication number Publication date
CZ280422B6 (cs) 1996-01-17
RO112765B1 (ro) 1997-12-30
OA09873A (en) 1994-09-15
AU647982B2 (en) 1994-03-31
EP0590096A4 (en) 1994-02-18
AU3141493A (en) 1993-07-19
MX9206954A (es) 1993-06-01
HUT71308A (en) 1995-11-28
BG61277B1 (en) 1997-04-30
WO1993012072A1 (en) 1993-06-24
EP0590096B1 (en) 1996-03-06
MW4993A1 (en) 1994-10-12
DE69208878D1 (de) 1996-04-11
DE69208878T2 (de) 1996-10-31
DE590096T1 (de) 1994-07-28
RU2092558C1 (ru) 1997-10-10
JPH0832243B2 (ja) 1996-03-29
US5177242A (en) 1993-01-05
FI931583A (fi) 1993-06-18
HU9301020D0 (en) 1993-11-29
CN1075166A (zh) 1993-08-11
TW242166B (es) 1995-03-01
CZ65193A3 (en) 1994-04-13
PL170490B1 (pl) 1996-12-31
JPH05507736A (ja) 1993-11-04
ATE135047T1 (de) 1996-03-15
KR970009155B1 (ko) 1997-06-07
FI931583A0 (fi) 1993-04-07
BR9205413A (pt) 1994-05-31
JPH06506674A (ja) 1994-07-28
CA2093826C (en) 1995-08-29
BG97619A (bg) 1994-03-31
IL104046A0 (en) 1993-05-13
EP0590096A1 (en) 1994-04-06
CA2093826A1 (en) 1993-06-18
SK36293A3 (en) 1993-10-06

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