BG61059B2 - Аналози на дономицина - Google Patents

Аналози на дономицина Download PDF

Info

Publication number
BG61059B2
BG61059B2 BG098211A BG9821193A BG61059B2 BG 61059 B2 BG61059 B2 BG 61059B2 BG 098211 A BG098211 A BG 098211A BG 9821193 A BG9821193 A BG 9821193A BG 61059 B2 BG61059 B2 BG 61059B2
Authority
BG
Bulgaria
Prior art keywords
donosaminylc
demethoxydonomycinone
sepimers
epimers
racemic
Prior art date
Application number
BG098211A
Other languages
Bulgarian (bg)
English (en)
Inventor
Bianca Patelli
Luigi Bernardi
Federico Arcamone
Aurelio Marco
Original Assignee
Farmitalia Carlo Erba S.R.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba S.R.L. filed Critical Farmitalia Carlo Erba S.R.L.
Publication of BG61059B2 publication Critical patent/BG61059B2/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
BG098211A 1974-06-12 1993-11-11 Аналози на дономицина BG61059B2 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2608374A GB1467383A (en) 1974-06-12 1974-06-12 Daunomycin analogues

Publications (1)

Publication Number Publication Date
BG61059B2 true BG61059B2 (bg) 1996-09-30

Family

ID=10238087

Family Applications (1)

Application Number Title Priority Date Filing Date
BG098211A BG61059B2 (bg) 1974-06-12 1993-11-11 Аналози на дономицина

Country Status (17)

Country Link
US (1) US4046878A (enFirst)
JP (1) JPS5840557B2 (enFirst)
AT (1) AT337363B (enFirst)
BE (1) BE830090A (enFirst)
BG (1) BG61059B2 (enFirst)
CH (1) CH611317A5 (enFirst)
DE (2) DE19375027I2 (enFirst)
DK (1) DK147304C (enFirst)
ES (1) ES438431A1 (enFirst)
FR (1) FR2274629A1 (enFirst)
GB (1) GB1467383A (enFirst)
HK (1) HK982A (enFirst)
MY (1) MY103666A (enFirst)
NL (1) NL173272C (enFirst)
SE (1) SE423633B (enFirst)
SU (1) SU645588A3 (enFirst)
ZA (1) ZA753722B (enFirst)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1506200A (en) * 1975-04-30 1978-04-05 Farmaceutici Italia Glycosides
GB1509875A (en) * 1976-06-14 1978-05-04 Farmaceutici Italia Optically active anthracyclinones and anthracycline glycosides
US4161480A (en) * 1978-06-05 1979-07-17 G. D. Searle & Co. Intermediates for the synthesis of 4-demethoxydaunorubicin
US4201773A (en) * 1978-07-26 1980-05-06 The United States Of America As Represented By The Department Of Health, Education And Welfare 7-O-(2,6-Dideoxy-α-L-lyxo-hexopyranosyl)-daunomycinone, desmethoxy daunomycinone, adriamycinone, and carminomycinone
IL55431A (en) * 1978-08-24 1982-07-30 Yeda Res & Dev Anthracycline type antibiotics,their preparation and pharmaceutical compositions comprising them
NL8001417A (nl) * 1979-03-17 1980-09-19 Erba Farmitalia Antitumorglycosiden.
JPS5673039A (en) * 1979-08-20 1981-06-17 Hoffmann La Roche Naphthacene derivative
EP0024727B1 (en) * 1979-09-01 1982-05-26 FARMITALIA CARLO ERBA S.p.A. Anthracycline glycosides, processes for their preparation and pharmaceutical composition containing them
DE3100968A1 (de) * 1980-01-16 1982-01-14 Farmitalia Carlo Erba S.p.A., 20159 Milano Anthracyclinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4348388A (en) * 1980-04-02 1982-09-07 G.D. Searle & Co. 11-Amino-11-deoxydaunorubicin and analogs
ZA814722B (en) * 1980-07-18 1982-07-28 Hoffmann La Roche Novel anthracycline glycosides
IT1210476B (it) * 1981-05-28 1989-09-14 Erba Farmitalia Antracicline.
GB8317037D0 (en) * 1983-06-23 1983-07-27 Erba Farmitalia 6-deoxyanthracyclines
US5138042A (en) * 1981-05-28 1992-08-11 Farmitalia Carlo Erba S.P.A. 6-deoxyanthracyclines
US4563444A (en) * 1982-05-26 1986-01-07 Farmitalia Carlo Erba S.P.A. Anthracycline glycosides, use and compositions containing same
US4604381A (en) * 1982-07-16 1986-08-05 Farmitalia Carlo Erba S.P.A. 4-demethoxy-13-dihydrodaunorubicin and use thereof
US4562177A (en) * 1982-08-17 1985-12-31 The Ohio State University Research Foundation 3'-Amino-2' halo-anthracycline antibiotics
US4564674A (en) * 1983-10-31 1986-01-14 Sagami Chemical Research Center Process for an anthracycline derivative, and an anthracyclinone derivative useful for the process
US4496485A (en) * 1983-11-25 1985-01-29 G. D. Searle & Co. Asymmetric 7-O-(substituted acetyl)-4-demethoxydaunomycinones
US4537882A (en) * 1984-05-10 1985-08-27 Ohio State University 4-Demethoxy-3'-desamino-2'-halo-anthracycline and pharmaceutical composition containing same
US4697005A (en) * 1985-03-20 1987-09-29 Ohio State University Research Foundation 1-fluoro, 4-fluoro, and 1,4-difluoro anthracycline anticancer antibiotics
US5124317A (en) * 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.P.A. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
NZ224252A (en) * 1987-04-21 1991-09-25 Erba Carlo Spa An anthracycline glycoside and its preparation
JPS63191263U (enFirst) * 1987-05-29 1988-12-09
GB2212154B (en) * 1987-11-10 1991-03-27 Erba Carlo Spa New 4-demethoxy anthracycline derivatives
GB8803301D0 (en) * 1988-02-12 1988-03-09 Erba Carlo Spa Process for preparation of 4-demethoxy-daunomycinone aglycone of 4-demethoxy-daunorubicin
GB8808475D0 (en) * 1988-04-11 1988-05-11 Erba Carlo Spa Process for preparing 4-demethoxydauno-mycinone
GB8818167D0 (en) * 1988-07-29 1988-09-01 Erba Carlo Spa Novel 4-substituted anthracyclinones & process for their preparation
WO1993018050A1 (en) * 1992-03-02 1993-09-16 Pfizer Inc. Sugar derivatives of macrolides
WO2004033666A2 (en) * 2002-10-11 2004-04-22 Board Of Regents, The University Of Texas System Method and compounds for inhibiting hec1 activity for the treatment of proliferative diseases
AU2006207321B2 (en) 2005-01-21 2012-09-06 Astex Therapeutics Limited Pharmaceutical compounds
JP5528807B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
JP5528806B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
CA2748057C (en) * 2008-12-23 2018-07-03 Pharmasset, Inc. Nucleoside phosphoramidates
EP2376515A1 (en) * 2008-12-23 2011-10-19 Pharmasset, Inc. Synthesis of purine nucleosides
US8551973B2 (en) * 2008-12-23 2013-10-08 Gilead Pharmasset Llc Nucleoside analogs
KR101806323B1 (ko) 2009-11-13 2017-12-07 다이이치 산쿄 유럽 게엠베하 Ｈｅｒ-３ 관련 질병을 치료하거나 예방하기 위한 물질 및 방법
CL2011000718A1 (es) 2010-03-31 2012-04-09 Gilead Pharmasset Llc Proceso para la preparacion de compuestos fosforados enantiomericos.
JP2013540694A (ja) 2010-08-06 2013-11-07 ウー３・フアルマ・ゲー・エム・ベー・ハー Ｈｅｒ３結合剤の前立腺治療における使用
DE102011113652A1 (de) 2011-09-19 2013-03-21 Heraeus Precious Metals Gmbh & Co. Kg Kristallisierung von Idarubicinhydrochlorid
TR201808733T4 (tr) 2011-10-03 2018-07-23 Mx Adjuvac Ab Kanser tedavisini ve gıda ile ilgili bileşikleri içeren tıp alanlarında amfipatik veya hidrofobik moleküller için taşıyıcı olarak nano-parçacıklar, preparasyon için proses ve bunların kullanımı.
WO2014163558A1 (en) 2013-04-01 2014-10-09 Moreinx Ab Nanoparticles, composed of sterol and saponin from quillaja saponaria molina process for preparation and use thereof as carrier for amphipatic of hydrphobic molecules in fields of medicine including cancer treatment and food related compounds
EP3669890A1 (en) 2018-12-18 2020-06-24 Croda International PLC Filamentous nanoparticles having vaccine adjuvant effect

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3427300A (en) * 1965-11-12 1969-02-11 Merck & Co Inc Anti-inflammatory steroid 2'-acetamido-2'-deoxy-glucoside compounds
US3803124A (en) * 1968-04-12 1974-04-09 Farmaceutici It Soc Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
US3686163A (en) * 1968-05-14 1972-08-22 Farmaceutici Italia Dihydrodaunomycin antibiotic and derivatives thereof

Also Published As

Publication number Publication date
DK147304C (da) 1984-12-17
AT337363B (de) 1977-06-27
FR2274629A1 (fr) 1976-01-09
DE2525633A1 (de) 1976-01-02
DE19375027I2 (de) 2002-06-13
JPS518260A (enFirst) 1976-01-23
ATA437375A (de) 1976-10-15
NL173272B (nl) 1983-08-01
FR2274629B1 (enFirst) 1980-01-11
US4046878A (en) 1977-09-06
DK256875A (da) 1975-12-13
SE423633B (sv) 1982-05-17
CH611317A5 (enFirst) 1979-05-31
NL173272C (nl) 1984-01-02
HK982A (en) 1982-01-22
DE2525633C3 (enFirst) 1979-10-18
NL7506745A (nl) 1975-12-16
AU8197975A (en) 1976-12-16
DK147304B (da) 1984-06-12
DE2525633B2 (enFirst) 1979-03-01
SE7506589L (sv) 1975-12-15
ES438431A1 (es) 1977-02-01
GB1467383A (en) 1977-03-16
SU645588A3 (ru) 1979-01-30
JPS5840557B2 (ja) 1983-09-06
BE830090A (fr) 1975-12-11
MY103666A (en) 1993-08-28
ZA753722B (en) 1976-09-29

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