DK256875A - Fremgangsmade til fremstilling af analoge til daunomycin - Google Patents

Fremgangsmade til fremstilling af analoge til daunomycin

Info

Publication number
DK256875A
DK256875A DK256875A DK256875A DK256875A DK 256875 A DK256875 A DK 256875A DK 256875 A DK256875 A DK 256875A DK 256875 A DK256875 A DK 256875A DK 256875 A DK256875 A DK 256875A
Authority
DK
Denmark
Prior art keywords
daunomycin
analogs
procedure
preparation
Prior art date
Application number
DK256875A
Other languages
English (en)
Other versions
DK147304B (da
DK147304C (da
Inventor
B Patelli
L Bernardi
F Arcamone
A D Marco
Original Assignee
Farmaceutici Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia filed Critical Farmaceutici Italia
Publication of DK256875A publication Critical patent/DK256875A/da
Publication of DK147304B publication Critical patent/DK147304B/da
Application granted granted Critical
Publication of DK147304C publication Critical patent/DK147304C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK256875A 1974-06-12 1975-06-09 Analogifremgangsmaade til fremstilling af (-) daunosaminyl-4-demethoxydaunomycinon som en blanding af (7s : 9r) og (7r : 9r) alfa-anomere DK147304C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2608374 1974-06-12
GB2608374A GB1467383A (en) 1974-06-12 1974-06-12 Daunomycin analogues

Publications (3)

Publication Number Publication Date
DK256875A true DK256875A (da) 1975-12-13
DK147304B DK147304B (da) 1984-06-12
DK147304C DK147304C (da) 1984-12-17

Family

ID=10238087

Family Applications (1)

Application Number Title Priority Date Filing Date
DK256875A DK147304C (da) 1974-06-12 1975-06-09 Analogifremgangsmaade til fremstilling af (-) daunosaminyl-4-demethoxydaunomycinon som en blanding af (7s : 9r) og (7r : 9r) alfa-anomere

Country Status (17)

Country Link
US (1) US4046878A (da)
JP (1) JPS5840557B2 (da)
AT (1) AT337363B (da)
BE (1) BE830090A (da)
BG (1) BG61059B2 (da)
CH (1) CH611317A5 (da)
DE (2) DE19375027I2 (da)
DK (1) DK147304C (da)
ES (1) ES438431A1 (da)
FR (1) FR2274629A1 (da)
GB (1) GB1467383A (da)
HK (1) HK982A (da)
MY (1) MY103666A (da)
NL (1) NL173272C (da)
SE (1) SE423633B (da)
SU (1) SU645588A3 (da)
ZA (1) ZA753722B (da)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1506200A (en) * 1975-04-30 1978-04-05 Farmaceutici Italia Glycosides
GB1509875A (en) * 1976-06-14 1978-05-04 Farmaceutici Italia Optically active anthracyclinones and anthracycline glycosides
US4161480A (en) * 1978-06-05 1979-07-17 G. D. Searle & Co. Intermediates for the synthesis of 4-demethoxydaunorubicin
US4201773A (en) * 1978-07-26 1980-05-06 The United States Of America As Represented By The Department Of Health, Education And Welfare 7-O-(2,6-Dideoxy-α-L-lyxo-hexopyranosyl)-daunomycinone, desmethoxy daunomycinone, adriamycinone, and carminomycinone
IL55431A (en) * 1978-08-24 1982-07-30 Yeda Res & Dev Anthracycline type antibiotics,their preparation and pharmaceutical compositions comprising them
NL8001417A (nl) * 1979-03-17 1980-09-19 Erba Farmitalia Antitumorglycosiden.
JPS5673039A (en) * 1979-08-20 1981-06-17 Hoffmann La Roche Naphthacene derivative
DE3060472D1 (en) * 1979-09-01 1982-07-15 Erba Farmitalia Anthracycline glycosides, processes for their preparation and pharmaceutical composition containing them
DE3100968A1 (de) * 1980-01-16 1982-01-14 Farmitalia Carlo Erba S.p.A., 20159 Milano Anthracyclinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4348388A (en) * 1980-04-02 1982-09-07 G.D. Searle & Co. 11-Amino-11-deoxydaunorubicin and analogs
ZA814722B (en) * 1980-07-18 1982-07-28 Hoffmann La Roche Novel anthracycline glycosides
US5138042A (en) * 1981-05-28 1992-08-11 Farmitalia Carlo Erba S.P.A. 6-deoxyanthracyclines
IT1210476B (it) * 1981-05-28 1989-09-14 Erba Farmitalia Antracicline.
GB8317037D0 (en) * 1983-06-23 1983-07-27 Erba Farmitalia 6-deoxyanthracyclines
US4563444A (en) * 1982-05-26 1986-01-07 Farmitalia Carlo Erba S.P.A. Anthracycline glycosides, use and compositions containing same
US4604381A (en) * 1982-07-16 1986-08-05 Farmitalia Carlo Erba S.P.A. 4-demethoxy-13-dihydrodaunorubicin and use thereof
US4562177A (en) * 1982-08-17 1985-12-31 The Ohio State University Research Foundation 3'-Amino-2' halo-anthracycline antibiotics
US4564674A (en) * 1983-10-31 1986-01-14 Sagami Chemical Research Center Process for an anthracycline derivative, and an anthracyclinone derivative useful for the process
US4496485A (en) * 1983-11-25 1985-01-29 G. D. Searle & Co. Asymmetric 7-O-(substituted acetyl)-4-demethoxydaunomycinones
US4537882A (en) * 1984-05-10 1985-08-27 Ohio State University 4-Demethoxy-3'-desamino-2'-halo-anthracycline and pharmaceutical composition containing same
US4697005A (en) * 1985-03-20 1987-09-29 Ohio State University Research Foundation 1-fluoro, 4-fluoro, and 1,4-difluoro anthracycline anticancer antibiotics
US5124317A (en) * 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.P.A. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
NZ224252A (en) * 1987-04-21 1991-09-25 Erba Carlo Spa An anthracycline glycoside and its preparation
JPS63191263U (da) * 1987-05-29 1988-12-09
GB2212154B (en) * 1987-11-10 1991-03-27 Erba Carlo Spa New 4-demethoxy anthracycline derivatives
GB8803301D0 (en) * 1988-02-12 1988-03-09 Erba Carlo Spa Process for preparation of 4-demethoxy-daunomycinone aglycone of 4-demethoxy-daunorubicin
GB8808475D0 (en) * 1988-04-11 1988-05-11 Erba Carlo Spa Process for preparing 4-demethoxydauno-mycinone
GB8818167D0 (en) * 1988-07-29 1988-09-01 Erba Carlo Spa Novel 4-substituted anthracyclinones & process for their preparation
AU3586293A (en) * 1992-03-02 1993-10-05 Pfizer Inc. Sugar derivatives of macrolides
AU2003299378A1 (en) * 2002-10-11 2004-05-04 Board Of Regents, The University Of Texas System Method and compounds for inhibiting hec1 activity for the treatment of proliferative diseases
KR101345002B1 (ko) 2005-01-21 2013-12-31 아스텍스 테라퓨틱스 리미티드 제약 화합물
WO2008044045A1 (en) 2006-10-12 2008-04-17 Astex Therapeutics Limited Pharmaceutical combinations
EP2073803B1 (en) 2006-10-12 2018-09-19 Astex Therapeutics Limited Pharmaceutical combinations
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
ES2623016T3 (es) * 2008-12-23 2017-07-10 Gilead Pharmasset Llc Fosforamidatos de nucleósido de 2-amino purina 6-O-sustituida
EA019295B1 (ru) 2008-12-23 2014-02-28 Джилид Фармассет, Ллс. Соединения пуриновых нуклеозидов и способ их получения
NZ593649A (en) * 2008-12-23 2013-11-29 Gilead Pharmasset Llc Nucleoside analogs
RS56741B1 (sr) 2009-11-13 2018-03-30 Daiichi Sankyo Europe Gmbh Materijal i postupci za lečenje ili prevenciju bolesti povezanih sa her-3
HUE026235T2 (en) 2010-03-31 2016-06-28 Gilead Pharmasset Llc Crystalline (S) -isopropyl 2 - (((S) - (((2R, 3R, 4R, 5R) -5- (2,4-dioxo-3,4-dihydropyrimidin-1 (2H) -IL) - 4-Fluoro-3-hydroxy-4-methyltetrahydrofuran-2-IL) methoxy) (phenoxy) phosphoryl) amino) propanoate
US20120156130A1 (en) 2010-08-06 2012-06-21 Thore Hettmann Use of her3 binding agents in prostate treatment
DE102011113652A1 (de) 2011-09-19 2013-03-21 Heraeus Precious Metals Gmbh & Co. Kg Kristallisierung von Idarubicinhydrochlorid
JP6050822B2 (ja) 2011-10-03 2016-12-21 モレインクス，エービー ナノ粒子、ナノ粒子の調製のための処理、および癌治療および食品関連化合物を含む医療分野における両親媒性分子または疎水性分子ための担体としてのナノ粒子の使用
AR095962A1 (es) 2013-04-01 2015-11-25 Moreinx Ab Nanopartículas, compuestas de esterol y saponina de quillaja saponaria molina, proceso para preparación y uso de las mismas como portadores para moléculas anfipáticas o hidrófobas en el campo de la medicina incluyendo tratamiento de cáncer y compuestos relacionados con alimentos
EP3669890A1 (en) 2018-12-18 2020-06-24 Croda International PLC Filamentous nanoparticles having vaccine adjuvant effect

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3427300A (en) * 1965-11-12 1969-02-11 Merck & Co Inc Anti-inflammatory steroid 2'-acetamido-2'-deoxy-glucoside compounds
US3803124A (en) * 1968-04-12 1974-04-09 Farmaceutici It Soc Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
US3686163A (en) * 1968-05-14 1972-08-22 Farmaceutici Italia Dihydrodaunomycin antibiotic and derivatives thereof

Also Published As

Publication number Publication date
NL173272B (nl) 1983-08-01
SE423633B (sv) 1982-05-17
DE2525633B2 (da) 1979-03-01
ES438431A1 (es) 1977-02-01
ATA437375A (de) 1976-10-15
NL173272C (nl) 1984-01-02
DE2525633A1 (de) 1976-01-02
JPS5840557B2 (ja) 1983-09-06
US4046878A (en) 1977-09-06
NL7506745A (nl) 1975-12-16
JPS518260A (da) 1976-01-23
DE2525633C3 (da) 1979-10-18
AT337363B (de) 1977-06-27
MY103666A (en) 1993-08-28
DK147304B (da) 1984-06-12
DK147304C (da) 1984-12-17
GB1467383A (en) 1977-03-16
SU645588A3 (ru) 1979-01-30
AU8197975A (en) 1976-12-16
BG61059B2 (bg) 1996-09-30
BE830090A (fr) 1975-12-11
ZA753722B (en) 1976-09-29
SE7506589L (sv) 1975-12-15
CH611317A5 (da) 1979-05-31
HK982A (en) 1982-01-22
FR2274629A1 (fr) 1976-01-09
FR2274629B1 (da) 1980-01-11
DE19375027I2 (de) 2002-06-13

Similar Documents

Publication Publication Date Title
DK256875A (da) Fremgangsmade til fremstilling af analoge til daunomycin
DK315375A (da) Fremgangsmade til fremstilling af sulfonater af s-adenosil-l-methionin
DK142237C (da) Kontinuerlig fremgangsmaade til fremstilling af alkoxysilaner
DK239075A (da) Fremgangsmade til fremstilling af iodbenzenderivater
DK144298C (da) Fremgangsmaade til fremstilling af alkyl-tert-butylethere
DK144160C (da) Analogifremgangsmaade til fremstilling af 8-thiomethylergoliner
DK217375A (da) Fremgangsmade til fremstilling af biphenylylderivater
DK136398C (da) Fremgangsmaade til fremstilling af et analgetisk-antipyretisk praeparat
DK385475A (da) Fremgangsmade til fremstilling af secoprostaglandiner
DK179675A (da) Fremgangsmade til fremstilling af 6-amino-5-r3-2,4-diaminopyrimidin-3-oxider
DK482175A (da) Fremgangsmade til fremstilling af anti-tumor glycosider
DK141849C (da) Fremgangsmaade til fremstilling af slagseje vinylaromat-podecopolymere
DK206375A (da) Fremgangsmade til fremstilling af thiaprostaglandiner
DK574075A (da) Fremgangsmade til fremstilling af 2-methoxybenzamider
DK211075A (da) Fremgangsmade til fremstilling af abietamidderivater
DK528475A (da) Fremgangsmade til fremstilling af tetramethylethylendiamin
DK543875A (da) Fremgangsmade til fremstilling af hydroxyphenylacetonitriler
DK583775A (da) Fremgangsmade til fremstilling af 3-fluorbenzodiazepiner
DK390975A (da) Fremgangsmade til fremstilling af omega-nor-cycloalkyl-13,14-dehydroprostaglandiner
DK145696C (da) Fremgangsmaade til fremstilling af 2-arylamino-2-imidazolin-derivater
DK48675A (da) Fremgangsmade til fremstilling af biphenylylderivater
DK271975A (da) Fremgangsmade til fremstilling af acylderivater
DK137539C (da) Fremgangsmaade til fremstilling af 11beta-fluor-4-androsten-3-oner
DK198175A (da) Fremgangsmade til fremstilling af indolkinolizidinderivater
DK593575A (da) Fremgangsmade til fremstilling af trichlorethylchlorformiat

Legal Events

Date Code Title Description
PUP Patent expired