BG51250A3 - Method for the preparation of thiadiazolo- and oxadiazolotetrahydroisoquinoline compound - Google Patents
Method for the preparation of thiadiazolo- and oxadiazolotetrahydroisoquinoline compound Download PDFInfo
- Publication number
- BG51250A3 BG51250A3 BG048339A BG4833980A BG51250A3 BG 51250 A3 BG51250 A3 BG 51250A3 BG 048339 A BG048339 A BG 048339A BG 4833980 A BG4833980 A BG 4833980A BG 51250 A3 BG51250 A3 BG 51250A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- oxadiazolotetrahydroisoquinoline
- thiadiazolo
- compound
- preparation
- acetyl
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 2
- UCTWMZQNUQWSLP-UHFFFAOYSA-N adrenaline Chemical compound CNCC(O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-UHFFFAOYSA-N 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- MOMFXATYAINJML-UHFFFAOYSA-N 2-Acetylthiazole Chemical group CC(=O)C1=NC=CS1 MOMFXATYAINJML-UHFFFAOYSA-N 0.000 abstract 1
- 108010002822 Phenylethanolamine N-Methyltransferase Proteins 0.000 abstract 1
- 102100028917 Phenylethanolamine N-methyltransferase Human genes 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000006193 diazotization reaction Methods 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5434379A | 1979-07-02 | 1979-07-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG51250A3 true BG51250A3 (en) | 1993-03-15 |
Family
ID=21990408
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG048339A BG51250A3 (en) | 1979-07-02 | 1980-07-01 | Method for the preparation of thiadiazolo- and oxadiazolotetrahydroisoquinoline compound |
Country Status (30)
| Country | Link |
|---|---|
| EP (1) | EP0023761B1 (de) |
| JP (1) | JPS5610192A (de) |
| KR (1) | KR840000396B1 (de) |
| AR (1) | AR225925A1 (de) |
| AT (1) | ATE6515T1 (de) |
| AU (1) | AU531641B2 (de) |
| BG (1) | BG51250A3 (de) |
| CA (1) | CA1129415A (de) |
| CS (1) | CS215064B2 (de) |
| DD (1) | DD151750A5 (de) |
| DE (1) | DE3066826D1 (de) |
| DK (1) | DK151029C (de) |
| ES (1) | ES492971A0 (de) |
| FI (1) | FI67221C (de) |
| GR (1) | GR69206B (de) |
| HU (1) | HU179382B (de) |
| IE (1) | IE50290B1 (de) |
| IL (1) | IL60426A (de) |
| IN (1) | IN160542B (de) |
| MX (1) | MX6317E (de) |
| NO (1) | NO801951L (de) |
| NZ (1) | NZ194156A (de) |
| PH (1) | PH17042A (de) |
| PL (2) | PL127098B1 (de) |
| PT (1) | PT71458A (de) |
| RO (1) | RO79707A (de) |
| SU (1) | SU1072809A3 (de) |
| YU (1) | YU171180A (de) |
| ZA (1) | ZA802987B (de) |
| ZW (1) | ZW14680A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4352809A (en) * | 1981-09-04 | 1982-10-05 | Smithkline Corporation | Method of producing alpha2 antagonism |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3988339A (en) * | 1974-02-08 | 1976-10-26 | Smithkline Corporation | Pharmaceutical compositions and methods of inhibiting phenylethanolamine N-methyltransferase |
| US3939164A (en) * | 1974-02-08 | 1976-02-17 | Smithkline Corporation | 7 AND 8-Halo substituted 1,2,3,4-tetrahydroisoquinoline compounds |
-
1980
- 1980-05-20 ZA ZA00802987A patent/ZA802987B/xx unknown
- 1980-06-25 CA CA354,710A patent/CA1129415A/en not_active Expired
- 1980-06-25 CS CS804525A patent/CS215064B2/cs unknown
- 1980-06-25 PH PH24191A patent/PH17042A/en unknown
- 1980-06-25 JP JP8720980A patent/JPS5610192A/ja active Pending
- 1980-06-26 IN IN485/DEL/80A patent/IN160542B/en unknown
- 1980-06-26 AU AU59677/80A patent/AU531641B2/en not_active Ceased
- 1980-06-26 EP EP80302140A patent/EP0023761B1/de not_active Expired
- 1980-06-26 PT PT71458A patent/PT71458A/pt unknown
- 1980-06-26 NZ NZ194156A patent/NZ194156A/xx unknown
- 1980-06-26 DE DE8080302140T patent/DE3066826D1/de not_active Expired
- 1980-06-26 AT AT80302140T patent/ATE6515T1/de not_active IP Right Cessation
- 1980-06-26 DK DK274280A patent/DK151029C/da not_active IP Right Cessation
- 1980-06-27 IL IL60426A patent/IL60426A/xx unknown
- 1980-06-27 NO NO801951A patent/NO801951L/no unknown
- 1980-06-27 ZW ZW146/80A patent/ZW14680A1/xx unknown
- 1980-06-28 KR KR1019800002551A patent/KR840000396B1/ko active
- 1980-06-30 DD DD80222268A patent/DD151750A5/de unknown
- 1980-06-30 IE IE1352/80A patent/IE50290B1/en unknown
- 1980-06-30 AR AR281587A patent/AR225925A1/es active
- 1980-06-30 RO RO80101552A patent/RO79707A/ro unknown
- 1980-07-01 BG BG048339A patent/BG51250A3/xx unknown
- 1980-07-01 PL PL1980225377A patent/PL127098B1/pl unknown
- 1980-07-01 FI FI802112A patent/FI67221C/fi not_active IP Right Cessation
- 1980-07-01 ES ES492971A patent/ES492971A0/es active Granted
- 1980-07-01 HU HU80801631A patent/HU179382B/hu unknown
- 1980-07-01 SU SU802942953A patent/SU1072809A3/ru active
- 1980-07-01 PL PL23061980A patent/PL230619A1/xx unknown
- 1980-07-01 GR GR62330A patent/GR69206B/el unknown
- 1980-07-01 YU YU01711/80A patent/YU171180A/xx unknown
- 1980-07-02 MX MX808900U patent/MX6317E/es unknown
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