BG46457A3 - Method for preparing of replaced thiazolidine- 4(s)- carbonic acids - Google Patents
Method for preparing of replaced thiazolidine- 4(s)- carbonic acidsInfo
- Publication number
- BG46457A3 BG46457A3 BG075405A BG7540586A BG46457A3 BG 46457 A3 BG46457 A3 BG 46457A3 BG 075405 A BG075405 A BG 075405A BG 7540586 A BG7540586 A BG 7540586A BG 46457 A3 BG46457 A3 BG 46457A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- thiazolidine
- preparing
- replaced
- carbonic acids
- general formula
- Prior art date
Links
- -1 benzofuryl- Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 230000002443 hepatoprotective effect Effects 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000003392 indanyl group Chemical group C1(CCC2=CC=CC=C12)* 0.000 abstract 1
- 125000002183 isoquinolinyl group Chemical group C1(=NC=CC2=CC=CC=C12)* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000001725 pyrenyl group Chemical group 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 125000002943 quinolinyl group Chemical group N1=C(C=CC2=CC=CC=C12)* 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU852388A HU200177B (en) | 1985-06-18 | 1985-06-18 | Process for producing thiazolidinecarboxylic acids and pharmaceutical compositions comprising such compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
BG46457A3 true BG46457A3 (en) | 1989-12-15 |
Family
ID=10959103
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG075405A BG46457A3 (en) | 1985-06-18 | 1986-06-18 | Method for preparing of replaced thiazolidine- 4(s)- carbonic acids |
Country Status (21)
Country | Link |
---|---|
US (1) | US4775675A (ja) |
EP (1) | EP0206197A1 (ja) |
JP (1) | JPS6248672A (ja) |
KR (1) | KR870000312A (ja) |
CN (1) | CN86104085A (ja) |
AR (1) | AR241532A1 (ja) |
BG (1) | BG46457A3 (ja) |
DD (1) | DD259866A5 (ja) |
DK (1) | DK259386A (ja) |
ES (1) | ES8800919A1 (ja) |
FI (1) | FI862608A (ja) |
GB (1) | GB2177089B (ja) |
GR (1) | GR861517B (ja) |
HU (1) | HU200177B (ja) |
IL (1) | IL78942A0 (ja) |
IN (1) | IN165646B (ja) |
NO (1) | NO862408L (ja) |
PH (1) | PH22790A (ja) |
PL (2) | PL148541B1 (ja) |
PT (1) | PT82769B (ja) |
SU (2) | SU1443800A3 (ja) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5740492A (en) * | 1980-08-22 | 1982-03-06 | Yamanouchi Pharmaceut Co Ltd | Novel 2-phenylimidazo 2,1-b benzothiazole derivative |
CN1030415A (zh) * | 1987-02-20 | 1989-01-18 | 山之内制药株式会社 | 饱和的杂环碳酰胺衍生物和它的制备方法 |
IT1223565B (it) * | 1987-12-21 | 1990-09-19 | Zambon Spa | Derivati dell'acido tiazolidin 4 carbossilico ad attivita' farmaceutica |
JP2726999B2 (ja) * | 1988-06-22 | 1998-03-11 | 日研化学株式会社 | イミダゾ[2,1−b]ベンゾチアゾール誘導体及び該化合物を有効成分とする抗潰瘍剤 |
GB9026114D0 (en) * | 1990-11-30 | 1991-01-16 | Norsk Hydro As | New compounds |
EP0494405B2 (en) * | 1991-01-10 | 2000-04-19 | Transcend Therapeutics, Inc. | Use of L-2-oxo thiazolidine-4-carboxylate for the treatment of pulmonary diseases |
US5747459A (en) * | 1991-02-04 | 1998-05-05 | Nestec, Ltd. | Method for insuring adequate intracellular glutathione in tissue |
US5849686A (en) * | 1991-03-11 | 1998-12-15 | Creative Biomolecules, Inc. | Morphogen-induced liver regeneration |
US5214062A (en) * | 1992-04-08 | 1993-05-25 | Clintec Nutrition Co. | Method and composition for treating immune disorders, inflammation and chronic infections |
US5430045A (en) * | 1992-04-23 | 1995-07-04 | Free Radical Sciences, Inc. | Method of reducing or preventing bone marrow hypoplasia |
US5447712A (en) * | 1993-12-09 | 1995-09-05 | Free Radical Sciences | Method of reducing cyclophosphamide induced hemorrhagic cystitis |
US6083966A (en) * | 1998-08-31 | 2000-07-04 | University Of Florida | Thiazoline acid derivatives |
CN1585639A (zh) * | 1998-09-21 | 2005-02-23 | 佛罗里达大学研究基金会 | 抗疟疾制剂 |
AU5319700A (en) | 1999-06-02 | 2000-12-18 | S. Mbua Ngale Efange | Nicotine receptor ligands |
AU6676100A (en) | 1999-08-17 | 2001-03-13 | University Of Saskatchewan Technologies Inc. | Improved treatment for acute physical insult to the central nervous system |
WO2005034949A1 (en) * | 2003-09-09 | 2005-04-21 | University Of Florida | Desferrithiocin derivatives and their use as iron chelators |
DE102004021658A1 (de) * | 2004-05-03 | 2005-12-01 | Rudy Dr. Susilo | Kombinationspräparate enthaltend 2-Methylthiazolidin-2,4-dicarbonsäure |
ES2614086T3 (es) | 2005-04-04 | 2017-05-29 | University Of Florida Research Foundation, Inc. | Análogos de poliéter de desferritiocina |
AU2008229472B2 (en) * | 2007-03-15 | 2013-03-14 | University Of Florida Research Foundation, Inc. | Desferrithiocin polyether analogues |
ES2761200T3 (es) | 2011-12-16 | 2020-05-19 | Univ Florida | Usos de análogos de 4'-desferritiocina |
EA030611B1 (ru) * | 2013-03-15 | 2018-08-31 | Кэнсер Рисерч Текнолоджи, Ллк | Способы и композиции для модуляции гамма-глутамилового цикла |
EP3071201A4 (en) | 2013-11-22 | 2017-04-26 | University of Florida Research Foundation, Inc. | Desferrithiocin analogs and uses thereof |
WO2016176343A1 (en) | 2015-04-27 | 2016-11-03 | University Of Florida Research Foundation, Incorporated | Metabolically programmed metal chelators and uses thereof |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR923562A (fr) * | 1946-02-01 | 1947-07-10 | Tube électronique | |
CH540234A (de) * | 1968-09-06 | 1973-08-15 | Degussa | Verfahren zur Herstellung von Penicillamin |
ES381037A1 (es) * | 1969-06-05 | 1973-07-01 | Ferlux | Acido tiazolidin dicarboxilico-2,4 y sus derivados y proce-dimiento para su obtencion. |
DE2116629A1 (en) * | 1971-04-05 | 1972-10-19 | Institutul de Biochimie, Bukarest | 4-thiazolidinecarboxylic acid derivs - with in vivo thiol liberating activity |
CA962269A (en) * | 1971-05-05 | 1975-02-04 | Robert E. Grahame (Jr.) | Thiazoles, and their use as insecticides |
US3947464A (en) * | 1972-07-28 | 1976-03-30 | Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler | Salts of phenylpropanolamine with thiazolidine carboxylic acids |
DE2446100C3 (de) * | 1974-09-26 | 1982-01-14 | Ludwig Merckle Kg Chem. Pharm. Fabrik, 7902 Blaubeuren | Phenoxyalkancarbonsäureamide von Thiazolidincarbonsäuren, Verfahren zu ihrer Herstellung und Arzneimittel |
GB1473752A (en) * | 1975-04-09 | 1977-05-18 | Rexolin Chem Ab | Composition of nitrofurans and its use in controlling formation of slime |
FR2356423A1 (fr) * | 1976-07-01 | 1978-01-27 | Oeriu Simion | Derives de l'acide thiazolidinecarboxylique, leur preparation et leur application comme medicaments |
EP0045281B1 (de) * | 1980-07-28 | 1985-05-08 | Ciba-Geigy Ag | Thiazolinderivate und Verfahren zu ihrer Herstellung |
-
1985
- 1985-06-18 HU HU852388A patent/HU200177B/hu not_active IP Right Cessation
-
1986
- 1986-05-27 IL IL78942A patent/IL78942A0/xx unknown
- 1986-06-02 DK DK259386A patent/DK259386A/da not_active Application Discontinuation
- 1986-06-04 IN IN416/CAL/86A patent/IN165646B/en unknown
- 1986-06-05 PH PH33857A patent/PH22790A/en unknown
- 1986-06-11 GR GR861517A patent/GR861517B/el unknown
- 1986-06-13 US US06/874,111 patent/US4775675A/en not_active Expired - Fee Related
- 1986-06-16 PL PL1986260106A patent/PL148541B1/pl unknown
- 1986-06-16 PT PT82769A patent/PT82769B/pt not_active IP Right Cessation
- 1986-06-16 DD DD86291335A patent/DD259866A5/de not_active IP Right Cessation
- 1986-06-16 PL PL1986273754A patent/PL149453B1/pl unknown
- 1986-06-16 GB GB8614616A patent/GB2177089B/en not_active Expired
- 1986-06-17 ES ES556135A patent/ES8800919A1/es not_active Expired
- 1986-06-17 JP JP61139386A patent/JPS6248672A/ja active Pending
- 1986-06-17 NO NO862408A patent/NO862408L/no unknown
- 1986-06-18 SU SU864027696A patent/SU1443800A3/ru active
- 1986-06-18 EP EP86108186A patent/EP0206197A1/de active Pending
- 1986-06-18 AR AR86304306A patent/AR241532A1/es active
- 1986-06-18 CN CN198686104085A patent/CN86104085A/zh active Pending
- 1986-06-18 BG BG075405A patent/BG46457A3/xx unknown
- 1986-06-18 FI FI862608A patent/FI862608A/fi not_active Application Discontinuation
- 1986-06-18 KR KR1019860004835A patent/KR870000312A/ko not_active IP Right Cessation
- 1986-11-19 SU SU864028509A patent/SU1475905A1/ru active
Also Published As
Publication number | Publication date |
---|---|
PT82769A (en) | 1986-07-01 |
GR861517B (en) | 1986-10-10 |
NO862408L (no) | 1986-12-19 |
FI862608A (fi) | 1986-12-19 |
PH22790A (en) | 1988-12-12 |
PT82769B (pt) | 1988-04-21 |
IL78942A0 (en) | 1986-09-30 |
GB2177089B (en) | 1989-07-19 |
NO862408D0 (no) | 1986-06-17 |
AR241532A1 (es) | 1992-08-31 |
IN165646B (ja) | 1989-12-02 |
ES556135A0 (es) | 1987-12-01 |
SU1443800A3 (ru) | 1988-12-07 |
JPS6248672A (ja) | 1987-03-03 |
US4775675A (en) | 1988-10-04 |
PL148541B1 (en) | 1989-10-31 |
SU1475905A1 (ru) | 1989-04-30 |
DK259386A (da) | 1986-12-19 |
DD259866A5 (de) | 1988-09-07 |
PL149453B1 (en) | 1990-02-28 |
GB2177089A (en) | 1987-01-14 |
CN86104085A (zh) | 1987-04-22 |
HUT41774A (en) | 1987-05-28 |
KR870000312A (ko) | 1987-02-17 |
FI862608A0 (fi) | 1986-06-18 |
GB8614616D0 (en) | 1986-07-23 |
HU200177B (en) | 1990-04-28 |
EP0206197A1 (de) | 1986-12-30 |
DK259386D0 (da) | 1986-06-02 |
ES8800919A1 (es) | 1987-12-01 |
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