BG34037A3 - A method of obtaining substituted n- methylene derivatives of thienamycine - Google Patents

A method of obtaining substituted n- methylene derivatives of thienamycine

Info

Publication number
BG34037A3
BG34037A3 BG7634723A BG3472376A BG34037A3 BG 34037 A3 BG34037 A3 BG 34037A3 BG 7634723 A BG7634723 A BG 7634723A BG 3472376 A BG3472376 A BG 3472376A BG 34037 A3 BG34037 A3 BG 34037A3
Authority
BG
Bulgaria
Prior art keywords
thienamycine
methylene derivatives
obtaining substituted
substituted
obtaining
Prior art date
Application number
BG7634723A
Other languages
Bulgarian (bg)
English (en)
Inventor
Christensen
Leanza
Wildonger
Original Assignee
Merck & Co Inc,Us
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc,Us filed Critical Merck & Co Inc,Us
Publication of BG34037A3 publication Critical patent/BG34037A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BG7634723A 1975-11-21 1976-11-19 A method of obtaining substituted n- methylene derivatives of thienamycine BG34037A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63429675A 1975-11-21 1975-11-21
US67626176A 1976-04-12 1976-04-12
US73365476A 1976-10-18 1976-10-18

Publications (1)

Publication Number Publication Date
BG34037A3 true BG34037A3 (en) 1983-06-15

Family

ID=27417545

Family Applications (1)

Application Number Title Priority Date Filing Date
BG7634723A BG34037A3 (en) 1975-11-21 1976-11-19 A method of obtaining substituted n- methylene derivatives of thienamycine

Country Status (27)

Country Link
AT (1) AT358168B (de)
AU (1) AU512383B2 (de)
BG (1) BG34037A3 (de)
CA (1) CA1083577A (de)
CH (2) CH632510A5 (de)
DD (1) DD127742A5 (de)
DE (1) DE2652679A1 (de)
DK (1) DK157401C (de)
EG (1) EG12261A (de)
ES (1) ES453501A1 (de)
FI (1) FI62306C (de)
FR (1) FR2332012A1 (de)
GB (1) GB1570990A (de)
GR (1) GR62072B (de)
HK (1) HK29683A (de)
HU (1) HU180865B (de)
IE (1) IE44433B1 (de)
IL (1) IL50911A (de)
KE (1) KE3286A (de)
NL (1) NL189297C (de)
NO (1) NO153298C (de)
NZ (1) NZ182630A (de)
PH (1) PH16714A (de)
PL (1) PL110937B1 (de)
PT (1) PT65865B (de)
SE (1) SE427841B (de)
SG (1) SG10983G (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593524A (en) * 1976-11-19 1981-07-15 Merck & Co Inc 1-carba-2-penem-3-carboxylic acids
SE436569B (sv) * 1977-05-05 1985-01-07 Merck & Co Inc Analogiforfarande for framstellning av tienamycinderivat
US4232030A (en) * 1977-09-15 1980-11-04 Merck & Co., Inc. Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone
DK153486C (da) * 1978-07-03 1988-11-28 Merck & Co Inc Analogifremgangsmaade til fremstilling af krystallinsk n-formimidoyl-thienamycin-monohydrat
EP0044170A1 (de) * 1980-07-11 1982-01-20 Beecham Group Plc Beta-Lactam-Antibiotika, ihre Herstellung und Verwendung
CA2089261A1 (en) * 1990-08-30 1992-03-01 John F.W. Keana Substituted amidines having high binding to the sigma receptor and the use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1004670A (en) * 1963-04-23 1965-09-15 Beecham Res Lab Penicillins
GB1348984A (en) * 1970-06-16 1974-03-27 Merck & Co Inc Antibiotics and processes for their production
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics

Also Published As

Publication number Publication date
SG10983G (en) 1983-12-16
NZ182630A (en) 1979-07-11
KE3286A (en) 1983-06-17
NL7612939A (nl) 1977-05-24
AU1964776A (en) 1978-05-25
DK523576A (da) 1977-05-22
CH633800A5 (en) 1982-12-31
GR62072B (en) 1979-02-20
PT65865B (en) 1978-10-12
NL189297B (nl) 1992-10-01
GB1570990A (en) 1980-07-09
ES453501A1 (es) 1978-03-01
NL189297C (nl) 1993-03-01
AT358168B (de) 1980-08-25
FI763308A (de) 1977-05-22
IL50911A (en) 1981-01-30
PT65865A (en) 1976-12-01
SE427841B (sv) 1983-05-09
FR2332012B1 (de) 1978-11-17
PL193809A1 (pl) 1978-01-16
DE2652679C2 (de) 1990-03-01
IL50911A0 (en) 1977-01-31
HU180865B (en) 1983-04-29
NO763958L (de) 1977-05-24
SE7612963L (sv) 1977-05-22
DK157401B (da) 1990-01-02
PH16714A (en) 1984-01-25
NO153298C (no) 1986-02-19
IE44433B1 (en) 1981-12-02
CH632510A5 (en) 1982-10-15
PL110937B1 (en) 1980-08-30
HK29683A (en) 1983-08-26
FI62306B (fi) 1982-08-31
FI62306C (fi) 1982-12-10
CA1083577A (en) 1980-08-12
NO153298B (no) 1985-11-11
EG12261A (en) 1978-12-31
IE44433L (en) 1977-05-21
ATA863476A (de) 1980-01-15
DD127742A5 (de) 1977-10-12
DE2652679A1 (de) 1977-06-02
FR2332012A1 (fr) 1977-06-17
DK157401C (da) 1990-05-21
AU512383B2 (en) 1980-10-09

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