BG25087A3 - A method of obtaining 2-tetrahydrofurfuryl-6,7-benzomorphanes and their salts - Google Patents

A method of obtaining 2-tetrahydrofurfuryl-6,7-benzomorphanes and their salts

Info

Publication number
BG25087A3
BG25087A3 BG7500029183A BG2918375A BG25087A3 BG 25087 A3 BG25087 A3 BG 25087A3 BG 7500029183 A BG7500029183 A BG 7500029183A BG 2918375 A BG2918375 A BG 2918375A BG 25087 A3 BG25087 A3 BG 25087A3
Authority
BG
Bulgaria
Prior art keywords
benzomorphanes
tetrahydrofurfuryl
salts
obtaining
Prior art date
Application number
BG7500029183A
Other languages
Bulgarian (bg)
English (en)
Inventor
Merz
Langbein
Walther
Stockhaus
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of BG25087A3 publication Critical patent/BG25087A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BG7500029183A 1974-03-09 1975-03-07 A method of obtaining 2-tetrahydrofurfuryl-6,7-benzomorphanes and their salts BG25087A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
BG25087A3 true BG25087A3 (en) 1978-07-12

Family

ID=5909593

Family Applications (3)

Application Number Title Priority Date Filing Date
BG7500030538A BG24814A4 (en) 1974-03-09 1975-03-07 Method of obtaining 2-tetrahydrofurfuryl-6,7-benzomorphanes and salts thereof
BG7500030537A BG24813A4 (en) 1974-03-09 1975-03-07 Method of obtaining 2-tetrahydrofurfuryl-6,7-benzomorphanes and salts thereof
BG7500029183A BG25087A3 (en) 1974-03-09 1975-03-07 A method of obtaining 2-tetrahydrofurfuryl-6,7-benzomorphanes and their salts

Family Applications Before (2)

Application Number Title Priority Date Filing Date
BG7500030538A BG24814A4 (en) 1974-03-09 1975-03-07 Method of obtaining 2-tetrahydrofurfuryl-6,7-benzomorphanes and salts thereof
BG7500030537A BG24813A4 (en) 1974-03-09 1975-03-07 Method of obtaining 2-tetrahydrofurfuryl-6,7-benzomorphanes and salts thereof

Country Status (25)

Country Link
JP (1) JPS5827275B2 (ja)
AT (1) AT344332B (ja)
BE (1) BE826440A (ja)
BG (3) BG24814A4 (ja)
CA (1) CA1049511A (ja)
CH (8) CH612425A5 (ja)
CS (1) CS188221B2 (ja)
DD (1) DD119236A5 (ja)
DE (1) DE2411382C3 (ja)
DK (1) DK137188C (ja)
ES (6) ES440348A1 (ja)
FI (1) FI63571C (ja)
FR (1) FR2262984B1 (ja)
GB (1) GB1496418A (ja)
HU (1) HU177408B (ja)
IE (1) IE40945B1 (ja)
IL (1) IL46760A (ja)
NL (1) NL7502724A (ja)
NO (1) NO141800C (ja)
PH (1) PH14127A (ja)
PL (3) PL93700B1 (ja)
RO (2) RO69617A (ja)
SE (1) SE421919B (ja)
SU (3) SU577982A3 (ja)
ZA (1) ZA751394B (ja)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
CZ291132B6 (cs) * 1995-03-10 2002-12-11 Photocure Asa Estery kyselin 5-aminolevulových a farmaceutický prostředek s jejich obsahem
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
ES2395081T3 (es) 2007-07-26 2013-02-08 Vitae Pharmaceuticals, Inc. Síntesis de inhibidores de la 11beta-hidroxiesteroide deshidrogenasa de tipo 1
TW200927115A (en) 2007-11-16 2009-07-01 Boehringer Ingelheim Int Aryl-and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
EP2229368A1 (en) 2007-12-11 2010-09-22 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
JP5490020B2 (ja) 2008-01-24 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状カルバゼート及びセミカルバジドインヒビター
CA2715290A1 (en) 2008-02-15 2009-08-20 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009134392A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009134387A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
JP5301563B2 (ja) 2008-05-01 2013-09-25 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター
CL2009001151A1 (es) 2008-05-13 2010-08-13 Boehringer Ingelheim Int Compuestos derivados de acidos carbociclicos aliciclicos de benzomorfanos, procedimiento de preparacion, composicion farmaceutica, utiles para tratar enfermedades influenciadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa, como trastornos metabolicos.
CA2729998A1 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2324018B1 (en) 2008-07-25 2013-09-04 Boehringer Ingelheim International GmbH Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
US8927539B2 (en) 2009-06-11 2015-01-06 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure
AR078887A1 (es) 2009-11-06 2011-12-07 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen.
EP2582698B1 (en) 2010-06-16 2016-09-14 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
WO2013025664A1 (en) 2011-08-17 2013-02-21 Boehringer Ingelheim International Gmbh Indenopyridine derivatives

Also Published As

Publication number Publication date
IL46760A (en) 1978-12-17
SU577983A3 (ru) 1977-10-25
SE7502592L (ja) 1975-09-10
JPS50123675A (ja) 1975-09-29
PL93700B1 (ja) 1977-06-30
JPS5827275B2 (ja) 1983-06-08
RO70051A (ro) 1980-12-30
ZA751394B (en) 1976-11-24
DE2411382B2 (de) 1979-01-18
FI63571B (fi) 1983-03-31
IE40945B1 (en) 1979-09-12
CH620439A5 (en) 1980-11-28
FR2262984B1 (ja) 1978-07-28
DE2411382C3 (de) 1979-09-06
FR2262984A1 (ja) 1975-10-03
PL93499B1 (ja) 1977-05-30
BG24813A4 (en) 1978-05-12
IL46760A0 (en) 1975-05-22
CH620440A5 (en) 1980-11-28
ATA153875A (de) 1977-11-15
CH622016A5 (en) 1981-03-13
IE40945L (en) 1975-09-09
FI63571C (fi) 1983-07-11
FI750652A (ja) 1975-09-10
ES440350A1 (es) 1977-03-16
CH622015A5 (en) 1981-03-13
DK137188B (da) 1978-01-30
NL7502724A (nl) 1975-09-11
CH622017A5 (en) 1981-03-13
SU588916A3 (ru) 1978-01-15
BG24814A4 (en) 1978-05-12
PH14127A (en) 1981-02-26
ES440349A1 (es) 1977-03-01
ES440347A1 (es) 1977-06-01
BE826440A (fr) 1975-09-08
CH620681A5 (en) 1980-12-15
DE2411382A1 (de) 1975-09-18
RO69617A (ro) 1980-08-15
HU177408B (en) 1981-10-28
NO141800B (no) 1980-02-04
DK137188C (da) 1978-07-03
ES440346A1 (es) 1977-03-01
SU577982A3 (ru) 1977-10-25
AT344332B (de) 1978-07-10
PL93699B1 (ja) 1977-06-30
NO750773L (ja) 1975-09-10
CH612425A5 (en) 1979-07-31
ES440345A1 (es) 1977-03-01
DK92975A (ja) 1975-09-10
NO141800C (no) 1980-06-04
SE421919B (sv) 1982-02-08
GB1496418A (en) 1977-12-30
CH622014A5 (en) 1981-03-13
AU7894275A (en) 1976-09-16
ES440348A1 (es) 1977-06-01
CS188221B2 (en) 1979-02-28
CA1049511A (en) 1979-02-27
DD119236A5 (ja) 1976-04-12

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