BG24813A4 - Метод за получаване на 2-тетрахидрофурфурил-6,7- бензоморфани и техните соли - Google Patents

Метод за получаване на 2-тетрахидрофурфурил-6,7- бензоморфани и техните соли

Info

Publication number
BG24813A4
BG24813A4 BG030537A BG3053775A BG24813A4 BG 24813 A4 BG24813 A4 BG 24813A4 BG 030537 A BG030537 A BG 030537A BG 3053775 A BG3053775 A BG 3053775A BG 24813 A4 BG24813 A4 BG 24813A4
Authority
BG
Bulgaria
Prior art keywords
benzomorphanes
tetrahydrofurfuryl
salts
preparation
Prior art date
Application number
BG030537A
Other languages
Bulgarian (bg)
English (en)
Inventor
Herbert Merz
Adolf Langbein
Gerhard Walther
Klaus Stockhaus
Original Assignee
C.H.Boehringer Sohn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C.H.Boehringer Sohn filed Critical C.H.Boehringer Sohn
Publication of BG24813A4 publication Critical patent/BG24813A4/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BG030537A 1974-03-09 1975-03-07 Метод за получаване на 2-тетрахидрофурфурил-6,7- бензоморфани и техните соли BG24813A4 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
BG24813A4 true BG24813A4 (bg) 1978-05-12

Family

ID=5909593

Family Applications (3)

Application Number Title Priority Date Filing Date
BG030537A BG24813A4 (bg) 1974-03-09 1975-03-07 Метод за получаване на 2-тетрахидрофурфурил-6,7- бензоморфани и техните соли
BG029183A BG25087A3 (bg) 1974-03-09 1975-03-07 Метод за получаване на 2-тетрахидрофупфупил-6,7 бензоморфани и техните соли
BG030538A BG24814A4 (bg) 1974-03-09 1975-03-07 Метод за получаване на 2-тетрахидрофурфурил-6,7 бензоморфани и техните соли

Family Applications After (2)

Application Number Title Priority Date Filing Date
BG029183A BG25087A3 (bg) 1974-03-09 1975-03-07 Метод за получаване на 2-тетрахидрофупфупил-6,7 бензоморфани и техните соли
BG030538A BG24814A4 (bg) 1974-03-09 1975-03-07 Метод за получаване на 2-тетрахидрофурфурил-6,7 бензоморфани и техните соли

Country Status (25)

Country Link
JP (1) JPS5827275B2 (en:Method)
AT (1) AT344332B (en:Method)
BE (1) BE826440A (en:Method)
BG (3) BG24813A4 (en:Method)
CA (1) CA1049511A (en:Method)
CH (8) CH612425A5 (en:Method)
CS (1) CS188221B2 (en:Method)
DD (1) DD119236A5 (en:Method)
DE (1) DE2411382C3 (en:Method)
DK (1) DK137188C (en:Method)
ES (6) ES440347A1 (en:Method)
FI (1) FI63571C (en:Method)
FR (1) FR2262984B1 (en:Method)
GB (1) GB1496418A (en:Method)
HU (1) HU177408B (en:Method)
IE (1) IE40945B1 (en:Method)
IL (1) IL46760A (en:Method)
NL (1) NL7502724A (en:Method)
NO (1) NO141800C (en:Method)
PH (1) PH14127A (en:Method)
PL (3) PL93700B1 (en:Method)
RO (2) RO69617A (en:Method)
SE (1) SE421919B (en:Method)
SU (3) SU577982A3 (en:Method)
ZA (1) ZA751394B (en:Method)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
CN1137087C (zh) * 1995-03-10 2004-02-04 光治疗公共有限公司 用作光化学疗法中的光致敏剂的5-氨基酮戊酸的酯
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
JP5470557B2 (ja) 2007-07-26 2014-04-16 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の阻害剤の合成
JP5769970B2 (ja) 2007-11-16 2015-08-26 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンゾモルファン及び関連骨格のアリール−及びヘテロアリールカルボニル誘導体、かかる化合物を含有する医薬及びこれらの使用
WO2009075835A1 (en) 2007-12-11 2009-06-18 Vitae Pharmaceutical, Inc CYCLIC UREA INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
CA2712500A1 (en) 2008-01-24 2009-07-30 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8598160B2 (en) 2008-02-15 2013-12-03 Vitae Pharmaceuticals, Inc. Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
WO2009134392A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
KR20110002492A (ko) 2008-05-01 2011-01-07 비타이 파마슈티컬즈, 인코포레이티드 11베타-하이드록시스테로이드 탈수소효소 1의 고리형 억제제
CA2723034A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2288596B1 (en) 2008-05-13 2016-11-30 Boehringer Ingelheim International GmbH Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
KR20110050459A (ko) 2008-07-25 2011-05-13 비타이 파마슈티컬즈, 인코포레이티드 11베타-하이드록시스테로이드 탈수소효소 1의 고리형 억제제
EP2324017B1 (en) 2008-07-25 2014-12-31 Boehringer Ingelheim International GmbH INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1
US8680093B2 (en) 2009-04-30 2014-03-25 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2011011123A1 (en) 2009-06-11 2011-01-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
UY33001A (es) 2009-11-06 2011-05-31 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina
EP2582698B1 (en) 2010-06-16 2016-09-14 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
WO2013025664A1 (en) 2011-08-17 2013-02-21 Boehringer Ingelheim International Gmbh Indenopyridine derivatives

Also Published As

Publication number Publication date
BG25087A3 (bg) 1978-07-12
CH622015A5 (en) 1981-03-13
NO141800B (no) 1980-02-04
CH620440A5 (en) 1980-11-28
ES440350A1 (es) 1977-03-16
BG24814A4 (bg) 1978-05-12
SU588916A3 (ru) 1978-01-15
FI63571C (fi) 1983-07-11
NO141800C (no) 1980-06-04
PL93699B1 (en:Method) 1977-06-30
RO69617A (ro) 1980-08-15
FI63571B (fi) 1983-03-31
DK92975A (en:Method) 1975-09-10
GB1496418A (en) 1977-12-30
CS188221B2 (en) 1979-02-28
IE40945B1 (en) 1979-09-12
SU577982A3 (ru) 1977-10-25
ZA751394B (en) 1976-11-24
ES440345A1 (es) 1977-03-01
IL46760A (en) 1978-12-17
SE7502592L (en:Method) 1975-09-10
CH612425A5 (en) 1979-07-31
CH622014A5 (en) 1981-03-13
FR2262984B1 (en:Method) 1978-07-28
RO70051A (ro) 1980-12-30
NO750773L (en:Method) 1975-09-10
CH622016A5 (en) 1981-03-13
PH14127A (en) 1981-02-26
DD119236A5 (en:Method) 1976-04-12
ES440349A1 (es) 1977-03-01
SU577983A3 (ru) 1977-10-25
AT344332B (de) 1978-07-10
CH620681A5 (en) 1980-12-15
DK137188C (da) 1978-07-03
DK137188B (da) 1978-01-30
ES440348A1 (es) 1977-06-01
CA1049511A (en) 1979-02-27
HU177408B (en) 1981-10-28
NL7502724A (nl) 1975-09-11
IL46760A0 (en) 1975-05-22
FI750652A7 (en:Method) 1975-09-10
PL93700B1 (en:Method) 1977-06-30
AU7894275A (en) 1976-09-16
ES440346A1 (es) 1977-03-01
IE40945L (en) 1975-09-09
DE2411382C3 (de) 1979-09-06
DE2411382A1 (de) 1975-09-18
CH620439A5 (en) 1980-11-28
JPS50123675A (en:Method) 1975-09-29
FR2262984A1 (en:Method) 1975-10-03
BE826440A (fr) 1975-09-08
DE2411382B2 (de) 1979-01-18
ES440347A1 (es) 1977-06-01
JPS5827275B2 (ja) 1983-06-08
PL93499B1 (en:Method) 1977-05-30
ATA153875A (de) 1977-11-15
CH622017A5 (en) 1981-03-13
SE421919B (sv) 1982-02-08

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