BG108370A - Кристални форми на азитромицин - Google Patents
Кристални форми на азитромицин Download PDFInfo
- Publication number
- BG108370A BG108370A BG108370A BG10837003A BG108370A BG 108370 A BG108370 A BG 108370A BG 108370 A BG108370 A BG 108370A BG 10837003 A BG10837003 A BG 10837003A BG 108370 A BG108370 A BG 108370A
- Authority
- BG
- Bulgaria
- Prior art keywords
- azithromycin
- ppm
- peaks
- crystalline
- solid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2813—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/282—Organic compounds, e.g. fats
- A61K9/2826—Sugars or sugar alcohols, e.g. sucrose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29256501P | 2001-05-22 | 2001-05-22 | |
US29774101P | 2001-06-12 | 2001-06-12 | |
US34304101P | 2001-12-21 | 2001-12-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
BG108370A true BG108370A (bg) | 2004-11-30 |
Family
ID=27404135
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG108370A BG108370A (bg) | 2001-05-22 | 2003-11-18 | Кристални форми на азитромицин |
Country Status (35)
Country | Link |
---|---|
US (10) | US6977243B2 (es) |
EP (1) | EP1390377B1 (es) |
JP (3) | JP2004530703A (es) |
KR (1) | KR100574153B1 (es) |
AP (1) | AP2003002906A0 (es) |
AR (1) | AR036022A1 (es) |
AT (2) | ATE404575T1 (es) |
AU (1) | AU2002256846B2 (es) |
BG (1) | BG108370A (es) |
BR (1) | BR0209918A (es) |
CA (1) | CA2391659C (es) |
CR (1) | CR7159A (es) |
CZ (1) | CZ20033154A3 (es) |
DE (2) | DE60228345D1 (es) |
DK (1) | DK1390377T3 (es) |
EA (2) | EA009611B1 (es) |
EE (1) | EE200300575A (es) |
ES (2) | ES2258142T3 (es) |
GE (1) | GEP20084399B (es) |
HU (1) | HUP0400446A2 (es) |
IL (1) | IL158591A0 (es) |
IS (1) | IS7007A (es) |
MA (1) | MA27023A1 (es) |
MX (1) | MXPA03010028A (es) |
MY (1) | MY129319A (es) |
NO (2) | NO321894B1 (es) |
NZ (2) | NZ529118A (es) |
PA (1) | PA8545701A1 (es) |
PE (1) | PE20021064A1 (es) |
PL (1) | PL367091A1 (es) |
PT (1) | PT1390377E (es) |
SK (1) | SK14402003A3 (es) |
TN (1) | TNSN03121A1 (es) |
WO (1) | WO2002094843A1 (es) |
YU (1) | YU91603A (es) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HRP20020231A2 (en) | 2002-03-18 | 2003-12-31 | Pliva D D | ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A |
CN1273142C (zh) * | 1998-11-30 | 2006-09-06 | 特瓦制药工业有限公司 | 阿齐霉素的乙醇化物,制备方法以及医药组合物 |
DE60114028T2 (de) * | 2000-08-23 | 2006-07-13 | Wockhardt Ltd. | Verfahren zur herstellung von wasserfreiem azithromycin |
KR100431431B1 (ko) * | 2001-04-25 | 2004-05-14 | 한미약품 주식회사 | 아지트로마이신 수화물의 1,2-프로필렌글리콜 내포화합물,그의 제조방법 및 그의 약학적 조성물 |
NZ529118A (en) * | 2001-05-22 | 2005-10-28 | Pfizer Prod Inc | Crystal forms of azithromycin |
ITMI20011762A1 (it) | 2001-08-10 | 2003-02-10 | Cosmo Spa | Esteri di 17alfa,21-diidrossipregnene, loro uso come agenti anti-androgenetici e procedimenti per la loro preparazione |
IL161259A0 (en) * | 2001-12-21 | 2004-09-27 | Pfizer Prod Inc | Methods for wet granulating azithromycin |
NZ532707A (en) * | 2001-12-21 | 2006-07-28 | Pfizer Prod Inc | Directly compressible formulations of azithromycin |
NZ534234A (en) | 2002-02-01 | 2007-05-31 | Pfizer Prod Inc | Dry granulated formulations of non-dihydrate form of azithromycin |
HRP20020614A2 (en) * | 2002-07-22 | 2004-06-30 | PLIVA-ISTRAŽIVAČKI INSTITUT d.o.o. | Rhombic pseudopolymorph of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin a |
CA2422972A1 (en) * | 2003-03-21 | 2004-09-21 | Apotex Inc. | Isopropanolate of azithromycin and method of manufacturing |
US20050013835A1 (en) * | 2003-07-15 | 2005-01-20 | Pfizer Inc. | Stable non-dihydrate azithromycin oral suspensions |
EP1648473B1 (en) * | 2003-07-24 | 2009-01-28 | PLIVA HRVATSKA d.o.o. | Single dose fast dissolving azithromycin |
EP1878432A1 (en) * | 2003-07-24 | 2008-01-16 | Pliva - Research and Development Ltd. | Single dose fast dissolving azithromycin |
AU2004311544A1 (en) * | 2003-11-17 | 2005-07-21 | Merck & Cie | Crystalline forms of (6R) -L-erythro-tetrahydrobiopterin dihydrochloride |
US7943585B2 (en) | 2003-12-22 | 2011-05-17 | Sandoz, Inc. | Extended release antibiotic composition |
US20060116336A1 (en) * | 2004-03-17 | 2006-06-01 | American Pharmaceutical Partners, Inc. | Lyophilized azithromycin formulation |
US7468428B2 (en) * | 2004-03-17 | 2008-12-23 | App Pharmaceuticals, Llc | Lyophilized azithromycin formulation |
US20050250714A1 (en) * | 2004-05-06 | 2005-11-10 | Lin Kangwen L | Crystalline forms of 9-(S)-erythromycylamine |
ES2370829T3 (es) * | 2004-06-02 | 2011-12-23 | Sandoz Ag | Producto intermedio de meropenem en forma cristalina. |
US7683162B2 (en) | 2004-08-30 | 2010-03-23 | Taro Pharmaceutical Industries Limited | Process of preparing a crystalline azithromycin monohydrate |
US8495244B2 (en) * | 2005-06-29 | 2013-07-23 | Jumpstart Wireless Corporation | System and method for dynamic automatic communication path selection, distributed device synchronization and task delegation |
US7750153B2 (en) * | 2005-07-05 | 2010-07-06 | Hetero Drugs Limited | Process for the preparation of didanosine using novel intermediates |
JP2009501206A (ja) * | 2005-07-14 | 2009-01-15 | ファイザー・プロダクツ・インク | 非晶質アジスロマイシン粒子の生成方法 |
EP1928826B1 (en) * | 2005-09-21 | 2013-04-24 | 4Sc Ag | Sulphonylpyrrole hydrochloride salts as histone deacetylases inhibitors |
EA014905B1 (ru) * | 2005-10-31 | 2011-02-28 | Янссен Фармацевтика Н.В. | Новый способ получения пиперазинильных производных бензамида |
US8558765B2 (en) * | 2005-11-07 | 2013-10-15 | Global Oled Technology Llc | Method and apparatus for uniformity and brightness correction in an electroluminescent display |
MX2008016008A (es) * | 2006-06-16 | 2009-01-16 | Lundbeck & Co As H | Formas cristalinas de 4-[2-(4-metilfenilsulfonil)-fenil] piperidina con inhibicion combinada de la recaptacion de serotonina y norepinefrina para el tratamiento del dolor neuropatico. |
US7919598B2 (en) * | 2006-06-28 | 2011-04-05 | Bristol-Myers Squibb Company | Crystal structures of SGLT2 inhibitors and processes for preparing same |
BRPI0717394A2 (pt) * | 2006-10-27 | 2013-10-15 | Signal Pharm Llc | Forma cristalina, composição farmacêutica, forma de dosagem unitária única, método para tratar ou prevenir uma doença ou condição, e, processo para preparar um composto |
CA2570949A1 (en) * | 2006-12-12 | 2008-06-12 | Apotex Pharmachem Inc. | Ibandronate sodium propylene glycol solvate and processes for the preparation thereof |
US7834195B2 (en) * | 2007-01-24 | 2010-11-16 | Apotex Pharmachem Inc. | Atorvastatin calcium propylene glycol solvates |
US7919676B2 (en) | 2007-08-03 | 2011-04-05 | Pioneer Hi-Bred International, Inc. | Msca1 nucleotide sequences impacting plant male fertility and method of using same |
ITMI20071616A1 (it) | 2007-08-03 | 2009-02-04 | Cosmo Spa | Processo enzimatico per l'ottenimento di 17-alfa monoesteri del cortexolone e/o suoi 9,11-deidroderivati. |
EP2085397A1 (en) * | 2008-01-21 | 2009-08-05 | Esteve Quimica, S.A. | Crystalline form of abacavir |
US7935817B2 (en) * | 2008-03-31 | 2011-05-03 | Apotex Pharmachem Inc. | Salt form and cocrystals of adefovir dipivoxil and processes for preparation thereof |
AR071318A1 (es) * | 2008-04-15 | 2010-06-09 | Basilea Pharmaceutica Ag | Benzhidril ester del acido (6r,7r)-7-{2-(5-amino-[1,2,4]tiadiazol-3-il)-2-[(z)-tritiloxiimino]-acetilamino}-3-[(r)-1'-terc-butoxicarbonil-2-oxo-[1,3']bipirrolidinil-(3e)-ilidenometil]-8-oxo-5-tia-1-aza-biciclo[4.2.0]oct-2-eno-2-carboxilico cristalino; su elaboracion y uso |
US8097719B2 (en) * | 2008-07-15 | 2012-01-17 | Genesen Labs | Meropenem intermediate in novel crystalline form and a method of manufacture of meropenem |
US8216363B2 (en) * | 2008-10-27 | 2012-07-10 | Illinois Institute Of Technology | Continuous antisolvent crystallization process and system using plug flow reactors |
US20100158821A1 (en) * | 2008-12-22 | 2010-06-24 | Eastman Chemical Company | Antimicrobial agents, compositions and products containing the same, and methods of using the compositions and products |
BRPI1009823A2 (pt) | 2009-03-13 | 2019-09-24 | Da Volterra Assistance Publique Hopitaux De Paris E Univ Paris Diderot Paris 7 | "composição compreendendo um sistema de dispensação de droga, conjunto de uma primeira e uma segunda composição, e, kit." |
US8106111B2 (en) | 2009-05-15 | 2012-01-31 | Eastman Chemical Company | Antimicrobial effect of cycloaliphatic diol antimicrobial agents in coating compositions |
KR101713453B1 (ko) | 2010-03-12 | 2017-03-07 | 오메로스 코포레이션 | Pde10 억제제 및 관련 조성물 및 방법 |
WO2012030957A2 (en) * | 2010-09-01 | 2012-03-08 | Arena Pharmaceuticals, Inc. | Non-hygroscopic salts of 5-ht2c agonists |
CN103930419B (zh) * | 2011-09-30 | 2016-06-01 | 广东东阳光药业有限公司 | 阿齐沙坦的晶型及其制备方法 |
WO2013088274A1 (en) | 2011-12-14 | 2013-06-20 | Wockhardt Limited | Anhydrous amorphous azithromycin composition free of azithromycin dihydrate |
NZ716462A (en) * | 2014-04-28 | 2017-11-24 | Omeros Corp | Optically active pde10 inhibitor |
NZ630810A (en) | 2014-04-28 | 2016-03-31 | Omeros Corp | Processes and intermediates for the preparation of a pde10 inhibitor |
AU2016250843A1 (en) | 2015-04-24 | 2017-10-12 | Omeros Corporation | PDE10 inhibitors and related compositions and methods |
EP3108879A1 (en) | 2015-06-25 | 2016-12-28 | Cassiopea S.p.A. | High concentration formulation |
JP2018535969A (ja) | 2015-11-04 | 2018-12-06 | オメロス コーポレーション | Pde10阻害剤の固体状態形態 |
CA3074831A1 (en) * | 2017-09-07 | 2019-03-14 | Athenex HK Innovative Limited | Solid forms of 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-n-benzylacetamide |
CN111303230B (zh) * | 2020-03-09 | 2021-07-13 | 中国食品药品检定研究院 | 一种黄体酮共晶物及其制备方法和用途 |
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SI7910768A8 (en) | 1979-04-02 | 1996-06-30 | Pliva Pharm & Chem Works | Process for pripering 11-aza-4-0-cladinosyl-6-0-desosaminyl-15-ethyl- 7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl- oxacyclopentadecane-2-one and their derivatives |
SI8110592A8 (en) | 1981-03-06 | 1996-06-30 | Pliva Pharm & Chem Works | Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof |
US4474768A (en) | 1982-07-19 | 1984-10-02 | Pfizer Inc. | N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor |
US4465674A (en) | 1983-09-06 | 1984-08-14 | Pfizer Inc. | Azahomoerythromycin D derivative and intermediates therefor |
UA27040C2 (uk) * | 1987-07-09 | 2000-02-28 | Пфайзер Інк. | Кристалічhий дигідрат азитроміциhу та спосіб одержаhhя кристалічhого дигідрату азитроміциhу |
WO1989002271A1 (en) | 1987-09-10 | 1989-03-23 | Pfizer | Azithromycin and derivatives as antiprotozoal agents |
US4983531A (en) * | 1990-02-12 | 1991-01-08 | Motorola, Inc. | Method of fabricating a single polysilicon bipolar transistor which is compatible with a method of fabricating CMOS transistors |
CN1093370A (zh) * | 1993-12-10 | 1994-10-12 | 北京市集才药物研究所 | 一种新的阿齐红霉素结晶及其制备方法 |
CN1034734C (zh) | 1993-12-10 | 1997-04-30 | 北京市集才药物研究所 | 一种新的阿齐红霉素结晶及其制备方法 |
US5605889A (en) * | 1994-04-29 | 1997-02-25 | Pfizer Inc. | Method of administering azithromycin |
DK0915899T3 (da) * | 1996-07-29 | 2004-11-29 | Abbott Lab | Fremstilling af krystallinsk form II af clarithromycin |
CN1161971A (zh) | 1997-01-03 | 1997-10-15 | 石家庄制药集团有限公司 | 一种阿齐霉素结晶及其制备方法 |
PT102130A (pt) | 1998-03-13 | 1999-09-30 | Hovione Sociedade Quimica S A | Processo de preparacao de dihidrato de azitromicina |
TW546302B (en) | 1998-05-08 | 2003-08-11 | Biochemie Sa | Improvements in macrolide production |
CA2245398C (en) * | 1998-08-21 | 2002-01-29 | Apotex Inc. | Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof |
KR100377159B1 (ko) * | 1998-09-09 | 2003-08-19 | 한미약품공업 주식회사 | 잔류 용매가 없는 클라리스로마이신의 결정형 2의 제조 방법 |
CN1273142C (zh) * | 1998-11-30 | 2006-09-06 | 特瓦制药工业有限公司 | 阿齐霉素的乙醇化物,制备方法以及医药组合物 |
AU5820400A (en) * | 1999-06-29 | 2001-01-31 | Biochemie S.A. | Macrolides |
ES2177373B1 (es) | 1999-11-26 | 2003-11-01 | Astur Pharma Sa | Preparacion de azitromicina en su forma no cristalina |
PT1246831E (pt) | 2000-01-04 | 2008-03-28 | Teva Pharma | Método de preparação de di-hidrato de azitromicina |
ES2162764B1 (es) | 2000-05-17 | 2003-04-01 | Ercros Ind Sa | Forma polimorfica del dihidrato de azitromicina, y su procedimiento deobtencion. |
WO2002007736A1 (en) | 2000-07-24 | 2002-01-31 | Cadila Pharmaceuticals Limited | The process for manufacturing of clear liquid pharmaceutical composition of azithromycin |
ATE320441T1 (de) | 2000-07-25 | 2006-04-15 | Silanes Sa De Cv Lab | Einstufiges verfahren zur herstellung von 7,16- |
ITBO20000471A1 (it) | 2000-07-31 | 2002-01-31 | Vieri Ridolfi | Dispositivo di supporto per prodotti da fumo particolarmente sigarette . |
ES2172417B1 (es) | 2000-07-31 | 2003-09-16 | Sint Quimica Sa | Nueva forma mejorada de azitromicina monohidrato de menor higroscopicidad, procedimiento de preparacion y composiciones farmaceuticas que la comprenden. |
WO2002009640A2 (en) | 2000-08-01 | 2002-02-07 | Shiva Prasad Singh | Process for the preparation of anhydrous azithromycin |
DE60114028T2 (de) | 2000-08-23 | 2006-07-13 | Wockhardt Ltd. | Verfahren zur herstellung von wasserfreiem azithromycin |
US6949519B2 (en) | 2000-11-27 | 2005-09-27 | Sandoz Ag | Macrolide solvates |
IN190080B (es) | 2001-01-29 | 2003-06-07 | Alembic Ltd | |
KR100431431B1 (ko) | 2001-04-25 | 2004-05-14 | 한미약품 주식회사 | 아지트로마이신 수화물의 1,2-프로필렌글리콜 내포화합물,그의 제조방법 및 그의 약학적 조성물 |
US6861413B2 (en) * | 2001-05-22 | 2005-03-01 | Pfizer Inc. | Stable non-dihydrate azithromycin oral suspensions |
NZ529118A (en) * | 2001-05-22 | 2005-10-28 | Pfizer Prod Inc | Crystal forms of azithromycin |
DE60232005D1 (de) | 2001-10-18 | 2009-05-28 | Teva Pharma | Stabilisierte azithromycin-zusammensetzungen |
-
2002
- 2002-05-01 NZ NZ529118A patent/NZ529118A/en unknown
- 2002-05-01 AP APAP/P/2003/002906A patent/AP2003002906A0/en unknown
- 2002-05-01 EA EA200500630A patent/EA009611B1/ru not_active IP Right Cessation
- 2002-05-01 AU AU2002256846A patent/AU2002256846B2/en not_active Ceased
- 2002-05-01 CA CA002391659A patent/CA2391659C/en not_active Expired - Fee Related
- 2002-05-01 PL PL02367091A patent/PL367091A1/xx not_active Application Discontinuation
- 2002-05-01 AT AT06110765T patent/ATE404575T1/de not_active IP Right Cessation
- 2002-05-01 MX MXPA03010028A patent/MXPA03010028A/es active IP Right Grant
- 2002-05-01 DK DK02726369T patent/DK1390377T3/da active
- 2002-05-01 CZ CZ20033154A patent/CZ20033154A3/cs unknown
- 2002-05-01 SK SK1440-2003A patent/SK14402003A3/sk unknown
- 2002-05-01 EA EA200301115A patent/EA007618B1/ru not_active IP Right Cessation
- 2002-05-01 PT PT02726369T patent/PT1390377E/pt unknown
- 2002-05-01 ES ES02726369T patent/ES2258142T3/es not_active Expired - Lifetime
- 2002-05-01 AT AT02726369T patent/ATE319730T1/de not_active IP Right Cessation
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- 2002-05-01 EP EP02726369A patent/EP1390377B1/en not_active Revoked
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2003
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2006
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