DK0915899T3 - Fremstilling af krystallinsk form II af clarithromycin - Google Patents

Fremstilling af krystallinsk form II af clarithromycin

Info

Publication number
DK0915899T3
DK0915899T3 DK97934319T DK97934319T DK0915899T3 DK 0915899 T3 DK0915899 T3 DK 0915899T3 DK 97934319 T DK97934319 T DK 97934319T DK 97934319 T DK97934319 T DK 97934319T DK 0915899 T3 DK0915899 T3 DK 0915899T3
Authority
DK
Denmark
Prior art keywords
methylerythromycin
alkyl
solvent
halo
nitro
Prior art date
Application number
DK97934319T
Other languages
English (en)
Inventor
Jih-Hua Liu
David A Riley
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27102712&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0915899(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/681,695 external-priority patent/US5844105A/en
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of DK0915899T3 publication Critical patent/DK0915899T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
DK97934319T 1996-07-29 1997-07-28 Fremstilling af krystallinsk form II af clarithromycin DK0915899T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/681,695 US5844105A (en) 1996-07-29 1996-07-29 Preparation of crystal form II of clarithromycin
US90027197A 1997-07-25 1997-07-25
EP97934319A EP0915899B1 (en) 1996-07-29 1997-07-28 Preparation of crystal form ii of clarithromycin

Publications (1)

Publication Number Publication Date
DK0915899T3 true DK0915899T3 (da) 2004-11-29

Family

ID=27102712

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97934319T DK0915899T3 (da) 1996-07-29 1997-07-28 Fremstilling af krystallinsk form II af clarithromycin

Country Status (12)

Country Link
EP (1) EP0915899B1 (da)
JP (4) JP4104660B2 (da)
KR (1) KR100524214B1 (da)
AT (1) ATE272646T1 (da)
AU (1) AU733646B2 (da)
CA (1) CA2261732C (da)
DE (3) DE97934319T1 (da)
DK (1) DK0915899T3 (da)
ES (1) ES2173057T3 (da)
IL (1) IL127833A (da)
PT (1) PT915899E (da)
WO (1) WO1998004574A1 (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5945405A (en) * 1997-01-17 1999-08-31 Abbott Laboratories Crystal form O of clarithromycin
CA2245398C (en) 1998-08-21 2002-01-29 Apotex Inc. Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof
KR100377159B1 (ko) * 1998-09-09 2003-08-19 한미약품공업 주식회사 잔류 용매가 없는 클라리스로마이신의 결정형 2의 제조 방법
GB9827355D0 (en) * 1998-12-11 1999-02-03 Biochemie Sa Organic compounds
KR20010008496A (ko) * 1999-07-01 2001-02-05 유충식 6-오-메틸 에리트로마이신의 제조방법
KR100322313B1 (ko) * 1999-10-21 2002-02-06 민경윤 클라리스로마이신 결정형 2의 제조방법 및 이에 사용되는 클라리스로마이신 포르메이트
US6627743B1 (en) 1999-12-03 2003-09-30 Abbott Laboratories 6-O-methylerythromycin A crystal form III
EP1254146B1 (en) * 1999-12-16 2005-08-24 Teva Pharmaceutical Industries Ltd. Processes for preparing clarithromycin polymorphs and novel polymorph iv
PL356645A1 (en) 2000-01-11 2004-06-28 Teva Pharmaceutical Industries Ltd. Processes for preparing clarithromycin polymorphs
CZ20023167A3 (cs) 2000-02-29 2003-10-15 Teva Pharmaceutical Industries Ltd. Způsob přípravy klaritromycinu a klaritromycinového meziproduktu, v podstatě prostého oximu a farmaceutický prostředek, který jej obsahuje
KR100361397B1 (ko) * 2000-03-15 2002-11-23 한미약품공업 주식회사 에리스로마이신 에이 9-오-트로필옥심 유도체를 이용한클라리스로마이신의 제조방법
KR100367981B1 (ko) * 2000-11-23 2003-01-14 한미약품공업 주식회사 클라리스로마이신 결정형 2의 제조 방법 및 이 방법에사용되는 결정성 클라리스로마이신 메실레이트 삼수화물
DE60122791T2 (de) * 2000-03-15 2007-10-04 Hanmi Pharm. Co., Ltd. Verfahren zur Herstellung von Clarythromycin mit nicht pharmazeutischer Qualität
KR100408848B1 (ko) * 2001-03-12 2003-12-06 주식회사 씨트리 클래리스로마이신의 정제방법
US6861413B2 (en) 2001-05-22 2005-03-01 Pfizer Inc. Stable non-dihydrate azithromycin oral suspensions
EP1652851A1 (en) * 2001-05-22 2006-05-03 Pfizer Products Inc. New crystal form of Azithromycin
HUP0400446A2 (hu) * 2001-05-22 2004-09-28 Pfizer Products Inc. Azitromicin kristályformái
KR100372254B1 (en) * 2002-07-15 2003-02-19 Korea United Pharm Inc Erythromycin a 9-o-pseudosaccharinyl oxime derivative and process for preparing clarithromycin using the same
AU2003271408B2 (en) * 2002-12-31 2008-07-17 Alembic Limited A process for the purification of roxithromycin
US7384921B2 (en) * 2004-02-20 2008-06-10 Enanta Pharmaceuticals, Inc. Polymorphic forms of 6-11 bicyclic ketolide derivatives
WO2008068593A2 (en) * 2006-12-05 2008-06-12 Pfizer Inc. Motilide polymorphs
DE102007016367A1 (de) * 2007-04-03 2008-10-09 Grünenthal GmbH Polymorph von Clarithromycin (Form V)
CN103087130B (zh) * 2013-02-06 2015-12-23 浙江国邦药业有限公司 一种克拉霉素晶型转换方法

Family Cites Families (15)

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Publication number Priority date Publication date Assignee Title
JPS572298A (en) * 1980-06-04 1982-01-07 Taisho Pharmaceut Co Ltd Erythromycin derivative
US4331803A (en) 1980-06-04 1982-05-25 Taisho Pharmaceutical Co., Ltd. Novel erythromycin compounds
JPS5782400A (en) 1980-11-12 1982-05-22 Taisho Pharmaceut Co Ltd Erythromycin derivative
JPS60214796A (ja) 1984-04-06 1985-10-28 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシン類の製法
JPS61103890A (ja) 1984-10-26 1986-05-22 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシンａ誘導体
US4670549A (en) 1985-03-18 1987-06-02 Taisho Pharmaceutical Co., Ltd. Method for selective methylation of erythromycin a derivatives
EP0260938B1 (en) 1986-09-18 1992-12-09 Taisho Pharmaceutical Co. Ltd Erythromycin a derivatives and method for preparing the same
JPH0755958B2 (ja) * 1986-10-03 1995-06-14 大正製薬株式会社 エリスロマイシンａ誘導体の製造方法
KR960000434B1 (ko) 1986-12-17 1996-01-06 다이쇼 세이야꾸 가부시끼가이샤 에리스로마이신 a유도체 및 그의 제조 방법
JP2526951B2 (ja) * 1986-12-17 1996-08-21 大正製薬株式会社 エリスロマイシンａ誘導体およびその製造方法
JP2782793B2 (ja) * 1988-06-15 1998-08-06 大正製薬株式会社 エリスロマイシンａ誘導体およびその製造方法
ZA922777B (en) * 1991-04-29 1993-10-15 Lilly Co Eli Pharmaceutical formulation containing dirithromycin
US5872229A (en) 1995-11-21 1999-02-16 Abbott Laboratories Process for 6-O-alkylation of erythromycin derivatives
US5719272A (en) 1996-04-02 1998-02-17 Abbott Laboratories 2'-protected 3'-dimethylamine, 9-etheroxime erythromycin A derivatives
US5837829A (en) 1996-04-02 1998-11-17 Abbott Laboratories 9-oximesilyl erythromycin a derivatives

Also Published As

Publication number Publication date
JP2009242411A (ja) 2009-10-22
AU3740597A (en) 1998-02-20
JP2013151542A (ja) 2013-08-08
DE69730138T2 (de) 2005-03-03
DE69730138D1 (de) 2004-09-30
JP4104660B2 (ja) 2008-06-18
PT915899E (pt) 2004-11-30
CA2261732A1 (en) 1998-02-05
JP2002514171A (ja) 2002-05-14
IL127833A (en) 2004-06-20
KR100524214B1 (ko) 2005-11-01
WO1998004574A1 (en) 1998-02-05
CA2261732C (en) 2001-07-24
AU733646B2 (en) 2001-05-17
ATE272646T1 (de) 2004-08-15
DE97934319T1 (de) 2004-08-26
EP0915899A1 (en) 1999-05-19
ES2173057T1 (es) 2002-10-16
IL127833A0 (en) 1999-10-28
ES2173057T3 (es) 2004-11-16
JP2006137765A (ja) 2006-06-01
KR20000029591A (ko) 2000-05-25
DE29724846U1 (de) 2004-12-16
EP0915899B1 (en) 2004-08-04

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