BG108324A - Нафтотиазин положителни алостерични модулатори на амра - рецептор - Google Patents

Нафтотиазин положителни алостерични модулатори на амра - рецептор Download PDF

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Publication number
BG108324A
BG108324A BG108324A BG10832403A BG108324A BG 108324 A BG108324 A BG 108324A BG 108324 A BG108324 A BG 108324A BG 10832403 A BG10832403 A BG 10832403A BG 108324 A BG108324 A BG 108324A
Authority
BG
Bulgaria
Prior art keywords
alkyl
different
halogen atoms
optionally substituted
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
BG108324A
Other languages
Bulgarian (bg)
English (en)
Inventor
Angelo Ceci
Klaus Klinder
Thomas Weiser
Karin Winter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH Co KG
Original Assignee
Boehringer Ingelheim Pharma GmbH Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma GmbH Co KG filed Critical Boehringer Ingelheim Pharma GmbH Co KG
Publication of BG108324A publication Critical patent/BG108324A/bg
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D279/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/021,2-Thiazines; Hydrogenated 1,2-thiazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
BG108324A 2001-05-17 2003-11-07 Нафтотиазин положителни алостерични модулатори на амра - рецептор Pending BG108324A (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10123952A DE10123952A1 (de) 2001-05-17 2001-05-17 Neue positive allosterische AMPA-Rezeptor Modulatoren (PAARM), Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
BG108324A true BG108324A (bg) 2004-12-30

Family

ID=7685080

Family Applications (1)

Application Number Title Priority Date Filing Date
BG108324A Pending BG108324A (bg) 2001-05-17 2003-11-07 Нафтотиазин положителни алостерични модулатори на амра - рецептор

Country Status (26)

Country Link
EP (1) EP1404340A1 (zh)
JP (1) JP2004529980A (zh)
KR (1) KR20040007572A (zh)
CN (1) CN1533278A (zh)
AR (1) AR036332A1 (zh)
BG (1) BG108324A (zh)
BR (1) BR0209796A (zh)
CA (1) CA2449189A1 (zh)
CO (1) CO5550460A2 (zh)
CZ (1) CZ20033112A3 (zh)
DE (1) DE10123952A1 (zh)
EA (1) EA006608B1 (zh)
EC (1) ECSP034852A (zh)
EE (1) EE200300566A (zh)
HR (1) HRP20030933A2 (zh)
HU (1) HUP0401273A3 (zh)
IL (1) IL158642A0 (zh)
MX (1) MXPA03010373A (zh)
NO (1) NO20035088L (zh)
NZ (1) NZ530154A (zh)
PL (1) PL364053A1 (zh)
SK (1) SK14222003A3 (zh)
UY (1) UY27290A1 (zh)
WO (1) WO2002100411A1 (zh)
YU (1) YU90403A (zh)
ZA (1) ZA200308466B (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20090047534A (ko) * 2006-08-31 2009-05-12 더 거버너스 오브 더 유니버시티 오브 앨버타 양성 알로스테릭 ampa 수용체 조절인자를 사용하여 호흡 저하를 억제하는 방법
CN111518058B (zh) * 2020-05-29 2021-03-09 四川大学华西医院 一种噁噻嗪类化合物及其用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4345297A (en) * 1996-09-17 1998-04-14 Regents Of The University Of California, The Benzothiadiazide derivatives and their use as allosteric up-modulators of the ampa receptor
JP2002518498A (ja) * 1998-06-25 2002-06-25 メルク エンド カムパニー インコーポレーテッド ナフト[1,8−de]チアジン−2−イルメチルカルバペネム抗菌物質
DE10004572A1 (de) * 2000-02-02 2001-08-09 Boehringer Ingelheim Pharma Neue positive allosterische AMPA-Rezeptor Modulatoren (PAARM), Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel

Also Published As

Publication number Publication date
CN1533278A (zh) 2004-09-29
SK14222003A3 (sk) 2004-05-04
AR036332A1 (es) 2004-09-01
NZ530154A (en) 2005-09-30
ZA200308466B (en) 2004-05-24
MXPA03010373A (es) 2004-03-16
CZ20033112A3 (en) 2004-03-17
CO5550460A2 (es) 2005-08-31
HUP0401273A2 (hu) 2004-10-28
IL158642A0 (en) 2004-05-12
CA2449189A1 (en) 2002-12-19
KR20040007572A (ko) 2004-01-24
HRP20030933A2 (en) 2004-04-30
ECSP034852A (es) 2003-12-24
PL364053A1 (en) 2004-12-13
JP2004529980A (ja) 2004-09-30
NO20035088D0 (no) 2003-11-14
NO20035088L (no) 2003-11-14
UY27290A1 (es) 2002-12-31
EA200301167A1 (ru) 2004-06-24
BR0209796A (pt) 2004-06-01
EP1404340A1 (en) 2004-04-07
DE10123952A1 (de) 2002-11-21
EE200300566A (et) 2004-02-16
WO2002100411A1 (en) 2002-12-19
HUP0401273A3 (en) 2006-11-28
EA006608B1 (ru) 2006-02-24
YU90403A (sh) 2006-05-25

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