BG107203A - Състав с активиращо действие - Google Patents

Състав с активиращо действие Download PDF

Info

Publication number
BG107203A
BG107203A BG107203A BG10720302A BG107203A BG 107203 A BG107203 A BG 107203A BG 107203 A BG107203 A BG 107203A BG 10720302 A BG10720302 A BG 10720302A BG 107203 A BG107203 A BG 107203A
Authority
BG
Bulgaria
Prior art keywords
hematopoietic
defibrotide
csf
activating
progenitor cells
Prior art date
Application number
BG107203A
Other languages
Bulgarian (bg)
English (en)
Inventor
Laura Ferro
Roberto Porta
Massimo Iacobelli
Alessandro GIANNI
Carmelo STELLA
Original Assignee
Gentium Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gentium Spa filed Critical Gentium Spa
Publication of BG107203A publication Critical patent/BG107203A/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BG107203A 2000-04-18 2002-10-17 Състав с активиращо действие BG107203A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00830293A EP1147777A1 (en) 2000-04-18 2000-04-18 Combination of defibrotide and G-CSF and its use to activate haematopoietic progenitors
PCT/EP2001/004105 WO2001078761A2 (en) 2000-04-18 2001-04-10 Mixture of defibrotide and g-csf ant its use for activating haematopoietic progenitors

Publications (1)

Publication Number Publication Date
BG107203A true BG107203A (bg) 2003-05-30

Family

ID=8175292

Family Applications (1)

Application Number Title Priority Date Filing Date
BG107203A BG107203A (bg) 2000-04-18 2002-10-17 Състав с активиращо действие

Country Status (31)

Country Link
US (1) US20040131588A1 (sl)
EP (3) EP1147777A1 (sl)
JP (1) JP5205668B2 (sl)
KR (1) KR100849491B1 (sl)
CN (1) CN1183962C (sl)
AT (2) ATE310532T1 (sl)
AU (2) AU5832201A (sl)
BG (1) BG107203A (sl)
CA (1) CA2406179C (sl)
CY (1) CY1104971T1 (sl)
CZ (1) CZ20023426A3 (sl)
DE (2) DE60115222T2 (sl)
DK (2) DK1276497T3 (sl)
EE (1) EE200200596A (sl)
ES (2) ES2252227T3 (sl)
HR (1) HRP20020835A2 (sl)
HU (1) HUP0300560A3 (sl)
IL (1) IL152328A (sl)
IS (1) IS2171B (sl)
MX (1) MXPA02010346A (sl)
NO (1) NO20024988L (sl)
NZ (1) NZ522016A (sl)
PL (1) PL358100A1 (sl)
PT (1) PT1621207E (sl)
RO (1) RO121006B1 (sl)
RU (1) RU2248216C2 (sl)
SI (1) SI21079B (sl)
SK (1) SK14892002A3 (sl)
UA (1) UA73566C2 (sl)
WO (1) WO2001078761A2 (sl)
ZA (1) ZA200208413B (sl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8771663B2 (en) 2000-04-18 2014-07-08 Gentium Spa Formulation having mobilising activity
WO2005017160A2 (en) * 2003-08-13 2005-02-24 Children's Hospital Medical Center Mobilization of hematopoietic cells
WO2005017161A2 (en) 2003-08-13 2005-02-24 Children's Hospital Medical Center Chimeric peptides for the regulation of gtpases
EP2103689A1 (en) * 2008-03-19 2009-09-23 Gentium S.p.A. Synthetic phosphodiester oligonucleotides and therapeutical uses thereof
RU2376985C1 (ru) * 2008-07-17 2009-12-27 Владислав Николаевич Ласкавый Средство для активации стволовых клеток
ES2694239T3 (es) 2010-11-12 2018-12-19 Gentium S.R.L. Defibrótido para su uso en profilaxis y/o tratamiento de la enfermedad de Injerto contra huésped (GVHD)
CA2874960C (en) 2012-06-22 2021-05-18 Gentium S.P.A. Euglobulin-based method for determining the biological activity of defibrotide
EP3026122A1 (en) 2014-11-27 2016-06-01 Gentium S.p.A. Cellular-based method for determining the potency of defibrotide
CN106567694A (zh) * 2016-11-14 2017-04-19 北京国泰通源技术有限公司 智能控水短节
CN110352246A (zh) * 2018-01-12 2019-10-18 赛尔美格公司 产生细胞囊和细胞囊管的方法
KR20220071274A (ko) 2019-11-13 2022-05-31 후지필름 가부시키가이샤 가식 필름, 성형물, 및 전자 디바이스

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2154279A1 (de) 1970-11-03 1972-05-25 Crinos Industria Farmaco Medikamente für das fibrinolytische System
IT1043823B (it) 1970-11-03 1980-02-29 Prephar Procedimento per l estrazione di acidi nucleici da organi animali
US3899481A (en) 1970-11-03 1975-08-12 Crinos Industria Farmaco Process for the controlled partial degradation of deoxyribonucleic acid extracted from animal organs
IT1206341B (it) 1984-02-16 1989-04-14 Crinos Industria Farmaco Composizione farmaceutica per il trattamento dell'ischemia acuta del miocardio.
US4694134A (en) 1985-05-28 1987-09-15 Ajax Magnethermic Corporation Apparatus for overheating edges of skelp for the production of compression welded pipe
IT1190313B (it) 1986-04-17 1988-02-16 Crinos Industria Farmaco Procedimento per l'ottenimento di polidesossiribonucleotidi chimicamente definiti e riproducibili e prodotto farmacologicamente attivo risultante
US5223609A (en) 1986-04-17 1993-06-29 Crinos Industria Farmacobiologica S.P.A. Process for obtaining chemically defined and reproducible polydeoxyribonucleotides
IT1223322B (it) * 1987-10-23 1990-09-19 Crinos Industria Farmaco Metodo per prevenire la formazione di coaguli sanguigni nel circuito extracorporeo di apparecchi di dialisi a composizione utile per esso
JP2907447B2 (ja) * 1988-08-24 1999-06-21 中外製薬株式会社 抗血栓剤
IT1231509B (it) * 1989-09-07 1991-12-07 Crinos Industria Farmaco Composizione farmceutica ad uso topico per la terapia della fragilita' capillare.
US5199942A (en) * 1991-06-07 1993-04-06 Immunex Corporation Method for improving autologous transplantation
US5977083A (en) * 1991-08-21 1999-11-02 Burcoglu; Arsinur Method for using polynucleotides, oligonucleotides and derivatives thereof to treat various disease states
JP3021906B2 (ja) * 1992-01-28 2000-03-15 松下電器産業株式会社 電動調理機
JPH08127539A (ja) * 1994-10-31 1996-05-21 Ajinomoto Co Inc ヒトｉｌ−１１を含有する末梢血幹細胞増加剤
WO1996016987A1 (fr) * 1994-11-30 1996-06-06 Chugai Seiyaku Kabushiki Kaisha Facteur thrombocytotique
ATE299030T1 (de) * 1996-07-10 2005-07-15 Meiji Dairies Corp Verwendung von proteinen aus der mk familie als hämatopoietischer faktor
AU1705599A (en) * 1997-11-26 1999-06-15 Allegheny University Of The Health Sciences Methods for mobilizing hematopoietic facilitating cells and hematopoietic stem cells into the peripheral blood
US6573372B2 (en) * 1999-01-07 2003-06-03 Heska Corporation Feline immunoglobulin E molecules and compositions there of

Also Published As

Publication number Publication date
JP5205668B2 (ja) 2013-06-05
AU2001258322B2 (en) 2006-03-16
DE60140015D1 (de) 2009-11-05
RU2002130719A (ru) 2004-03-27
CZ20023426A3 (cs) 2003-05-14
IL152328A0 (en) 2003-05-29
EP1276497B1 (en) 2005-11-23
HRP20020835A2 (en) 2005-10-31
NO20024988L (no) 2002-12-02
NZ522016A (en) 2004-10-29
EE200200596A (et) 2004-04-15
CA2406179A1 (en) 2001-10-25
EP1276497A2 (en) 2003-01-22
EP1621207B1 (en) 2009-09-23
EP1147777A1 (en) 2001-10-24
EP1621207A3 (en) 2006-11-22
KR100849491B1 (ko) 2008-07-31
IS6581A (is) 2002-10-14
CA2406179C (en) 2012-03-27
EP1621207A2 (en) 2006-02-01
ATE310532T1 (de) 2005-12-15
SI21079A (sl) 2003-06-30
CN1183962C (zh) 2005-01-12
DE60115222D1 (de) 2005-12-29
RU2248216C2 (ru) 2005-03-20
RO121006B1 (ro) 2006-11-30
DK1276497T3 (da) 2006-03-27
CY1104971T1 (el) 2010-03-03
ES2335776T3 (es) 2010-04-05
WO2001078761A2 (en) 2001-10-25
HUP0300560A2 (hu) 2003-06-28
NO20024988D0 (no) 2002-10-16
JP2004500437A (ja) 2004-01-08
IS2171B (is) 2006-11-15
IL152328A (en) 2009-12-24
KR20030010603A (ko) 2003-02-05
SK14892002A3 (sk) 2003-06-03
MXPA02010346A (es) 2004-09-06
WO2001078761A3 (en) 2002-01-24
ATE443524T1 (de) 2009-10-15
PL358100A1 (en) 2004-08-09
DE60115222T2 (de) 2006-08-10
AU5832201A (en) 2001-10-30
SI21079B (sl) 2006-08-31
UA73566C2 (en) 2005-08-15
CN1434719A (zh) 2003-08-06
ES2252227T3 (es) 2006-05-16
PT1621207E (pt) 2009-12-28
DK1621207T3 (da) 2010-02-01
ZA200208413B (en) 2003-10-17
US20040131588A1 (en) 2004-07-08
HUP0300560A3 (en) 2005-07-28

Similar Documents

Publication Publication Date Title
US9782429B2 (en) Formulation having mobilizing activity
JP4727988B2 (ja) エリスロポエチンの使用
Colletti et al. Proliferative effects of CXC chemokines in rat hepatocytes in vitro and in vivo
Steward et al. Recombinant human granulocyte macrophage colony stimulating factor (rhGM-CSF) given as daily short infusions–a phase I dose-toxicity study
BG107203A (bg) Състав с активиращо действие
AU2001258322A1 (en) Formulation having mobilising activity
US7220407B2 (en) G-CSF therapy as an adjunct to reperfusion therapy in the treatment of acute myocardial infarction
CZ120298A3 (cs) Použití proteinu získaného z chemokinu savců
KR20190039145A (ko) 대체 면역요법으로서의 il-12의 용도
JP3501801B2 (ja) 組み換えコロニー刺激因子―１の使用
EP0800402A1 (en) Mobilisation of haematopoietic cells
KR101144687B1 (ko) Ｇ－ｃｓｆ 를 함유하는 선유아세포 동원제 및 창상 치료제
Shibuya et al. Marked improvement of thrombocytopenia in a murine model of idiopathic thrombocytopenic purpura by pegylated recombinant human megakaryocyte growth and development factor
JPH08169841A (ja) 血小板増多促進剤