BG106851A - Calcium dicarboxylate ethers, methods of making same, and their use for the treatment of vascular disease and diabetes therewith - Google Patents

Calcium dicarboxylate ethers, methods of making same, and their use for the treatment of vascular disease and diabetes therewith

Info

Publication number
BG106851A
BG106851A BG106851A BG10685102A BG106851A BG 106851 A BG106851 A BG 106851A BG 106851 A BG106851 A BG 106851A BG 10685102 A BG10685102 A BG 10685102A BG 106851 A BG106851 A BG 106851A
Authority
BG
Bulgaria
Prior art keywords
treatment
methods
vascular disease
making same
diabetes
Prior art date
Application number
BG106851A
Other languages
Bulgarian (bg)
English (en)
Inventor
Howard ANDO
Donald BUTLER
Gary DOZEMAN
Original Assignee
Warner-Lambert Company Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner-Lambert Company Llc filed Critical Warner-Lambert Company Llc
Publication of BG106851A publication Critical patent/BG106851A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/125Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235Saturated compounds containing more than one carboxyl group
    • C07C59/305Saturated compounds containing more than one carboxyl group containing ether groups, groups, groups, or groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
BG106851A 2000-01-25 2002-06-20 Calcium dicarboxylate ethers, methods of making same, and their use for the treatment of vascular disease and diabetes therewith BG106851A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17782300P 2000-01-25 2000-01-25
PCT/IB2001/000026 WO2001055078A1 (en) 2000-01-25 2001-01-11 Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetes therewith

Publications (1)

Publication Number Publication Date
BG106851A true BG106851A (en) 2003-01-31

Family

ID=22650106

Family Applications (1)

Application Number Title Priority Date Filing Date
BG106851A BG106851A (en) 2000-01-25 2002-06-20 Calcium dicarboxylate ethers, methods of making same, and their use for the treatment of vascular disease and diabetes therewith

Country Status (39)

Country Link
EP (1) EP1259474B1 (ja)
JP (1) JP4750995B2 (ja)
KR (1) KR20020073182A (ja)
CN (1) CN1395555A (ja)
AP (1) AP2002002587A0 (ja)
AR (1) AR029436A1 (ja)
AT (1) ATE431326T1 (ja)
AU (1) AU2214001A (ja)
BG (1) BG106851A (ja)
BR (1) BR0107763A (ja)
CA (1) CA2397960C (ja)
CO (1) CO5261537A1 (ja)
CZ (1) CZ20022474A3 (ja)
DE (1) DE60138686D1 (ja)
DK (1) DK1259474T3 (ja)
DZ (1) DZ3239A1 (ja)
EA (1) EA004862B1 (ja)
EE (1) EE200200404A (ja)
ES (1) ES2324281T3 (ja)
GE (1) GEP20053428B (ja)
GT (1) GT200100015A (ja)
HN (1) HN2001000011A (ja)
HU (1) HUP0204422A3 (ja)
IL (1) IL150541A0 (ja)
IS (1) IS6442A (ja)
MA (1) MA26867A1 (ja)
MX (1) MXPA02007223A (ja)
NO (1) NO20023526L (ja)
NZ (1) NZ519550A (ja)
OA (1) OA12166A (ja)
PA (1) PA8510601A1 (ja)
PE (1) PE20011064A1 (ja)
PL (1) PL357076A1 (ja)
SK (1) SK10622002A3 (ja)
SV (1) SV2002000290A (ja)
TN (1) TNSN01013A1 (ja)
UY (1) UY26550A1 (ja)
WO (1) WO2001055078A1 (ja)
ZA (1) ZA200205880B (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1045691T1 (en) * 1997-12-12 2005-04-30 Warner-Lambert Company Llc Statin-carboxyalkylether combinations
KR20050058454A (ko) * 2002-08-22 2005-06-16 워너-램버트 캄파니 엘엘씨 골관절염의 치료 방법
US20090069591A1 (en) * 2005-04-19 2009-03-12 Eisai R & D Management Co., Ltd. Calcium Bis [ (2S) -3- [3-[ (2S) -3- (4-Chloro-2-Cyanophenoxy) -2- Fluoropropoxy]Phenyl] -2- Isopropoxypropionate] and Intermediate Thereof
US7816405B2 (en) 2005-04-19 2010-10-19 Eisai R&D Management Co., Ltd. Calcium bis [(2S)-3-[3-[(2S)-3-(4-chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl ]-2-isopropoxypropionate] and intermediate thereof
KR20170083535A (ko) * 2014-11-14 2017-07-18 젬파이어 세러퓨틱스 인코포레이티드 α,ω-다이카복실산-말단 다이알케인 에터를 제조하기 위한 방법 및 중간체
EP3612171A4 (en) * 2017-04-18 2020-10-21 Gemphire Therapeutics Inc. GEMCABED, PHARMACEUTICAL SALT THEREOF, COMPOSITIONS THEREOF, AND METHOD OF USE THEREOF
KR20210093900A (ko) * 2018-10-18 2021-07-28 젬파이어 세러퓨틱스 인코포레이티드 젬카빈, 이의 약학적으로 허용가능한 염, 이의 조성물 및 이의 사용 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648387A (en) 1995-03-24 1997-07-15 Warner-Lambert Company Carboxyalkylethers, formulations, and treatment of vascular diseases
NZ503982A (en) 1997-12-12 2002-03-28 Warner Lambert Co Statin-carboxyalkylether combinations useful for treating vascular disorders and diabetes mellitus

Also Published As

Publication number Publication date
DZ3239A1 (fr) 2001-08-02
BR0107763A (pt) 2002-11-12
GEP20053428B (en) 2005-01-25
HUP0204422A2 (en) 2003-05-28
SK10622002A3 (sk) 2003-07-01
AP2002002587A0 (en) 2002-09-30
CO5261537A1 (es) 2003-03-31
SV2002000290A (es) 2002-07-16
PA8510601A1 (es) 2002-08-26
ATE431326T1 (de) 2009-05-15
EE200200404A (et) 2003-10-15
IS6442A (is) 2002-06-25
HUP0204422A3 (en) 2003-08-28
EA004862B1 (ru) 2004-08-26
MXPA02007223A (es) 2002-11-29
JP2003520835A (ja) 2003-07-08
NZ519550A (en) 2003-11-28
AR029436A1 (es) 2003-06-25
CA2397960C (en) 2008-09-09
EP1259474B1 (en) 2009-05-13
NO20023526D0 (no) 2002-07-24
HN2001000011A (es) 2001-06-13
NO20023526L (no) 2002-08-27
PE20011064A1 (es) 2001-10-22
CA2397960A1 (en) 2001-08-02
GT200100015A (es) 2001-10-19
MA26867A1 (fr) 2004-12-20
CN1395555A (zh) 2003-02-05
TNSN01013A1 (fr) 2005-11-10
IL150541A0 (en) 2003-02-12
JP4750995B2 (ja) 2011-08-17
WO2001055078A1 (en) 2001-08-02
ES2324281T3 (es) 2009-08-04
DE60138686D1 (de) 2009-06-25
EA200200641A1 (ru) 2002-12-26
PL357076A1 (en) 2004-07-12
CZ20022474A3 (cs) 2003-06-18
KR20020073182A (ko) 2002-09-19
DK1259474T3 (da) 2009-07-20
OA12166A (en) 2003-11-07
ZA200205880B (en) 2003-07-23
AU2214001A (en) 2001-08-07
UY26550A1 (es) 2001-08-27
EP1259474A1 (en) 2002-11-27

Similar Documents

Publication Publication Date Title
DE50102490D1 (de) Verwendung von substituierten imidazo [1,2-a]pyridin-, -pyrimidin- und -pyrazin-3-yl-amin-derivaten zur herstellung von medikamenten zur nos-inhibierung
DE69522947D1 (en) Phenylxanthin-derivate
PT711282E (pt) Compostos inibidores de pde iv e de fnt
WO2005016261A3 (en) Aripiprazole and haloperidol pamoate salts
HRP20080689T3 (en) Imidazoline derivatives having cb1-antagonistic activity
GB0112348D0 (en) Compounds
ATE389395T1 (de) Substituierte 2-aminotetraline zur vorbeugenden behandlung von morbus parkinson
PE20010402A1 (es) Derivados de 1,5-dihidropirrol-2-ona sustituida
HK1079526A1 (en) A novel pyrazine compound and its use in the manufacture of a medicament for treating diseases related to serotonin
ES2187261A1 (es) Compuestos de eteres y amidas y su preparacion, como agentes anti-diabeticos.
BG106851A (en) Calcium dicarboxylate ethers, methods of making same, and their use for the treatment of vascular disease and diabetes therewith
IL153561A0 (en) 4-alkoxy cyclohexane-1-amino carboxylic acid esters and method for the production thereof
ATE366107T1 (de) Verwendung von sulfodehydroabietinsäure zur behandlung entzündlicher darmerkrankungen
PL344056A1 (en) Piperididinyl and n-amidinopiperidinyl derivatives
IL166103A0 (en) Pyrrolidine derivatives and their use
DE60139409D1 (de) Pharmazeutische zusammensetzungen die ein dibenzocyclooctanlignanderivat enthalten zur vorbeugung und behandlung neurodegenerativer erkrankungen
EP1694645A4 (en) AMLODIPINE GENTISATE AND METHOD OF MANUFACTURE
MXPA05012743A (es) Composicion de limpieza mejorada.
BR0306701A (pt) Composto, sal do composto, sal de cálcio, método de preparação de um sal, composição farmacêutica, método de preparação de uma composição, e, uso de um sal
WO2006074919A3 (de) 3 -AMINO- 6-ARYL (BZW.6-HETEROARYL) -THIENO [2 , 3-B] PYRIDIN-2-CARBONSÄUREAMIDE, DIESE ENTHALTENDE PHARMAZEUTISCHE ZUBEREITUNGEN UND IHRE VERWENDUNG ALS INHIBITOREN DER TNFα-FREISETZUNG
EA199900675A2 (ru) Полиморф моногидрата зополрестата
DE69930621D1 (de) Medizinische zusammensetzungen zur unmittelbaren freisetzung bei oraler anwendung
IL149544A0 (en) N-ACYLPYRROLIDIN-2-YLALKYLBENZAMIDINE DERIVATIVES AS INHIBITORS OF FACTOR Xa
SG146685A1 (en) Dihydroporphine derivatives, processes for their preparation, and pharmaceutical compositions containing them
WO2002030876A3 (en) Cyclic carboxylic acids as integrin antagonists