BG104425A - 6,11-мостови еритромицинови производни - Google Patents

6,11-мостови еритромицинови производни Download PDF

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Publication number
BG104425A
BG104425A BG104425A BG10442500A BG104425A BG 104425 A BG104425 A BG 104425A BG 104425 A BG104425 A BG 104425A BG 10442500 A BG10442500 A BG 10442500A BG 104425 A BG104425 A BG 104425A
Authority
BG
Bulgaria
Prior art keywords
compound
formula
arylene
group
heteroarylene
Prior art date
Application number
BG104425A
Other languages
Bulgarian (bg)
English (en)
Inventor
Yat S. Or
George Griesgraber
Leping Li
Daniel T. Chu
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of BG104425A publication Critical patent/BG104425A/bg

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
BG104425A 1997-10-29 2000-05-11 6,11-мостови еритромицинови производни BG104425A (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96040097A 1997-10-29 1997-10-29
US15826998A 1998-09-22 1998-09-22
PCT/US1998/022941 WO1999021864A1 (fr) 1997-10-29 1998-10-29 Derives d'erythromycine a pont 6,11

Publications (1)

Publication Number Publication Date
BG104425A true BG104425A (bg) 2001-01-31

Family

ID=26854886

Family Applications (1)

Application Number Title Priority Date Filing Date
BG104425A BG104425A (bg) 1997-10-29 2000-05-11 6,11-мостови еритромицинови производни

Country Status (23)

Country Link
EP (1) EP1027361B1 (fr)
JP (1) JP2001521038A (fr)
KR (1) KR20010031591A (fr)
CN (1) CN1278266A (fr)
AR (1) AR015986A1 (fr)
AT (1) ATE239750T1 (fr)
AU (1) AU1286799A (fr)
BG (1) BG104425A (fr)
BR (1) BR9813317A (fr)
CA (1) CA2307828A1 (fr)
CO (1) CO4990972A1 (fr)
DE (1) DE69814441T2 (fr)
DK (1) DK1027361T3 (fr)
ES (1) ES2198766T3 (fr)
HU (1) HUP0004323A2 (fr)
IL (1) IL134996A0 (fr)
NO (1) NO20002099L (fr)
PL (1) PL340253A1 (fr)
PT (1) PT1027361E (fr)
SK (1) SK6342000A3 (fr)
TR (1) TR200001140T2 (fr)
TW (1) TW486485B (fr)
WO (1) WO1999021864A1 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6437106B1 (en) * 1999-06-24 2002-08-20 Abbott Laboratories Process for preparing 6-o-substituted erythromycin derivatives
US6472372B1 (en) * 2000-12-06 2002-10-29 Ortho-Mcneil Pharmaceuticals, Inc. 6-O-Carbamoyl ketolide antibacterials
US6713455B2 (en) 2001-09-17 2004-03-30 Ortho-Mcneil Pharmaceutical, Inc. 6-O-carbamate-11,12-lacto-ketolide antimicrobials
CA2469304A1 (fr) 2001-12-05 2003-06-19 Ortho-Mcneil Pharmaceutical, Inc. Agents anti-bacteriens de 6-o-acyl cetolide
US6753318B1 (en) 2002-07-25 2004-06-22 Enanta Pharmaceuticals, Inc. 6,11-4-carbon bridged erythromycin derivatives
US6841664B2 (en) * 2002-07-25 2005-01-11 Enanra Pharmaceuticals, Inc. 6,11-4-carbon bridged ketolides
JP2005536465A (ja) 2002-05-13 2005-12-02 エナンタ ファーマシューティカルズ インコーポレイテッド ６，１１二環式エリスロマイシン誘導体
US7910558B2 (en) * 2002-05-13 2011-03-22 Enanta Pharmaceuticals, Inc. Bridged macrocyclic compounds and processes for the preparation thereof
AU2003229037B8 (en) * 2002-05-13 2009-07-02 Enanta Pharmaceuticals, Inc. 6,11 bicyclic erythromycin derivatives
US7273853B2 (en) 2002-05-13 2007-09-25 Enanta Pharmaceuticals, Inc. 6-11 bicyclic ketolide derivatives
US6645941B1 (en) * 2003-03-26 2003-11-11 Enanta Pharmaceuticals, Inc. 6,11-3C-bicyclic 9a-azalide derivatives
US7414030B2 (en) 2004-01-07 2008-08-19 Enanta Pharmaceuticals, Inc. 6-11 Bicyclic erythromycin derivatives
WO2005070113A2 (fr) 2004-01-09 2005-08-04 Enanta Pharmaceuticals, Inc. Derives d'erythromycine bicycliques 9-n substitues en c6-c11
WO2005080408A1 (fr) * 2004-01-23 2005-09-01 Enanta Pharmaceuticals, Inc. Composes macrocycliques pontes et procedes de preparation desdits composes
US7384921B2 (en) 2004-02-20 2008-06-10 Enanta Pharmaceuticals, Inc. Polymorphic forms of 6-11 bicyclic ketolide derivatives
US7384922B2 (en) 2005-05-04 2008-06-10 Enanta Pharmaceuticals, Inc. 6-11 bridged oxime erythromycin derivatives
US7589067B2 (en) 2005-10-12 2009-09-15 Enanta Pharmaceuticals, Inc. 6, 11-bridged tricyclic macrolides
US8273720B2 (en) 2007-09-17 2012-09-25 Enanta Pharmaceuticals, Inc. 6,11-bicyclolides: bridged biaryl macrolide derivatives
US11673910B2 (en) 2017-04-28 2023-06-13 Zikani Therapeutics, Inc. Macrolides with modified desosamine sugars and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0876388T3 (da) * 1995-11-08 2004-06-07 Abbott Lab Tricykliske erythromycinderivater

Also Published As

Publication number Publication date
NO20002099L (no) 2000-06-29
JP2001521038A (ja) 2001-11-06
PT1027361E (pt) 2003-09-30
TR200001140T2 (tr) 2001-05-21
EP1027361A1 (fr) 2000-08-16
CA2307828A1 (fr) 1999-05-06
IL134996A0 (en) 2001-05-20
EP1027361B1 (fr) 2003-05-07
AR015986A1 (es) 2001-05-30
DE69814441D1 (de) 2003-06-12
DK1027361T3 (da) 2003-08-25
SK6342000A3 (en) 2000-09-12
WO1999021864A1 (fr) 1999-05-06
NO20002099D0 (no) 2000-04-25
ATE239750T1 (de) 2003-05-15
ES2198766T3 (es) 2004-02-01
AU1286799A (en) 1999-05-17
BR9813317A (pt) 2000-08-22
HUP0004323A2 (hu) 2001-02-28
TW486485B (en) 2002-05-11
PL340253A1 (en) 2001-01-29
KR20010031591A (ko) 2001-04-16
DE69814441T2 (de) 2004-04-08
CN1278266A (zh) 2000-12-27
CO4990972A1 (es) 2000-12-26

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