BG103231A - Методи и междинни съединения за получаване на заместени хроманолови производни - Google Patents

Методи и междинни съединения за получаване на заместени хроманолови производни

Info

Publication number
BG103231A
BG103231A BG103231A BG10323199A BG103231A BG 103231 A BG103231 A BG 103231A BG 103231 A BG103231 A BG 103231A BG 10323199 A BG10323199 A BG 10323199A BG 103231 A BG103231 A BG 103231A
Authority
BG
Bulgaria
Prior art keywords
methods
preparation
intermediate compounds
chromanol derivatives
substituted chromanol
Prior art date
Application number
BG103231A
Other languages
English (en)
Other versions
BG63542B1 (bg
Inventor
Joel HAWKINS
Anthony Piscopio
Stephane Caron
Sarah KELLY
Jefrey RAGGON
Michael CASTALDI
Robert DUGGER
Sally RUGGERI
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of BG103231A publication Critical patent/BG103231A/bg
Publication of BG63542B1 publication Critical patent/BG63542B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/50—Halogenated unsaturated alcohols containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Изобретението се отнася до методи за получаване на съединения с формула@@или техни енантиомери. Въвформулата бензоената киселинна част е свързана в 6-та или 7-ма позиция на хромановия пръстен, а R1,R2 и R3 имат значенията, посочени в описанието. Изобретението се отнася и до междинни съединения, полезни при получаването на посочените съединения.
BG103231A 1996-09-16 1999-03-09 Методи и междинни съединения за получаване на заместени хроманолови производни BG63542B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2637296P 1996-09-16 1996-09-16
PCT/IB1997/001024 WO1998011085A1 (en) 1996-09-16 1997-08-25 Processes and intermediates for preparing substituted chromanol derivatives

Publications (2)

Publication Number Publication Date
BG103231A true BG103231A (bg) 1999-12-30
BG63542B1 BG63542B1 (bg) 2002-04-30

Family

ID=21831429

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103231A BG63542B1 (bg) 1996-09-16 1999-03-09 Методи и междинни съединения за получаване на заместени хроманолови производни

Country Status (39)

Country Link
US (4) US6096906A (bg)
EP (1) EP0925292B1 (bg)
JP (1) JP3117730B2 (bg)
KR (1) KR100339164B1 (bg)
CN (1) CN1108298C (bg)
AP (1) AP726A (bg)
AT (1) ATE249452T1 (bg)
AU (1) AU713701B2 (bg)
BG (1) BG63542B1 (bg)
BR (1) BR9711482A (bg)
CA (1) CA2265043C (bg)
CO (1) CO4600635A1 (bg)
DE (1) DE69724801T2 (bg)
DK (1) DK0925292T3 (bg)
DZ (1) DZ2308A1 (bg)
EA (1) EA002204B1 (bg)
ES (1) ES2206738T3 (bg)
GT (3) GT199700104A (bg)
HN (1) HN1997000127A (bg)
HR (1) HRP970497B1 (bg)
ID (1) ID19613A (bg)
IL (1) IL128732A0 (bg)
IS (1) IS4980A (bg)
MA (1) MA24319A1 (bg)
NO (1) NO991254L (bg)
NZ (1) NZ334214A (bg)
OA (1) OA10995A (bg)
PA (1) PA8437901A1 (bg)
PE (1) PE109798A1 (bg)
PL (1) PL332351A1 (bg)
PT (1) PT925292E (bg)
SK (1) SK31399A3 (bg)
TN (1) TNSN97155A1 (bg)
TR (1) TR199900592T2 (bg)
TW (1) TW449579B (bg)
UA (1) UA58520C2 (bg)
WO (1) WO1998011085A1 (bg)
YU (1) YU13299A (bg)
ZA (1) ZA978291B (bg)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6436987B1 (en) * 2000-06-08 2002-08-20 Pfizer Inc. Crystalline forms of (3S-trans)-2-[3,4-dihydro-4-hydroxy-3-(phenylmethyl)-2H-1-benzopyran-7-yl]-4-(trifluoromethyl)-benzoic acid
WO2002060888A1 (en) * 2001-01-30 2002-08-08 Pfizer Products Inc. Processes for preparing chromanylbenzoic acids
AU4239302A (en) * 2001-06-28 2003-01-02 Pfizer Products Inc. Benzoic acid substituted benzopyrans for the treatment of atherosclerosis
EP2181103B1 (en) 2007-07-23 2015-08-05 The Board Of Trustees Of The University Of Illinois System for controlling the reactivity of boronic acids
WO2010036921A2 (en) 2008-09-26 2010-04-01 The Board Of Trustees Of The University Of Illinois Slow release of organoboronic acids in cross-coupling reactions
KR20120083366A (ko) * 2009-09-02 2012-07-25 이 아이 듀폰 디 네모아 앤드 캄파니 플루오로비닐에테르 작용화된 방향족 부분을 포함하는 폴리에스테르
WO2011028771A2 (en) * 2009-09-02 2011-03-10 E. I. Du Pont De Nemours And Company Polyester films with improved oil repellency
US20110218319A1 (en) * 2009-09-02 2011-09-08 E. I. Du Pont De Nemours And Company Polyaramid films comprising fluorovinylether functionalized aromatic moieties
WO2011028767A2 (en) 2009-09-02 2011-03-10 E. I. Du Pont De Nemours And Company Fluoroether functionalized aromatic diesters and derivatives thereof
TW201127822A (en) * 2009-09-02 2011-08-16 Du Pont Fluorinated 4-oxo-chroman-carboxylates
TW201118113A (en) * 2009-09-02 2011-06-01 Du Pont Polyaramid comprising fluorovinylether functionalized aromatic moieties
WO2011103435A2 (en) * 2010-02-18 2011-08-25 The Board Of Trustees Of The University Of Illinois Methods for forming protected organoboronic acids
EP3268085A4 (en) 2015-03-13 2018-10-31 The Board of Trustees of The Leland Stanford Junior University Ltb4 inhibition to prevent and treat human lymphedema

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9119920D0 (en) * 1991-09-18 1991-10-30 Glaxo Group Ltd Chemical compounds
JP2813464B2 (ja) * 1992-01-23 1998-10-22 フアイザー・インコーポレイテツド ベンゾピラン及び関連ｌｔｂ▲下４▼アンタゴニスト
MX9300312A (es) * 1992-01-23 1993-07-31 Pfizer Antagonistas benzopiranicos y relacionado de ltb.
AU4650493A (en) * 1992-10-21 1994-05-09 Pfizer Inc. (Enantiomeric cis)-3-(4,6-dihydroxychroman-3-YL-methyl)benzoic acids
PL308474A1 (en) * 1992-10-21 1995-08-07 Pfizer Sulphonamidic derivatives of hydroxy substituted cycloalkylic and heterocyclic compounds with condensed benzene ring
KR100232340B1 (ko) * 1994-10-13 1999-12-01 디. 제이. 우드, 스피겔 알렌 제이 류코트리엔 b4(ltb4) 길항물질로서의 벤조피란 및 벤조-축합된 화합물
MX9702731A (es) * 1994-10-13 1997-06-28 Pfizer Compuestos de benzopirano y benzo fusionados, composiciones que los contienen y uso de los mismos.
US5539128A (en) * 1994-11-30 1996-07-23 Pfizer Inc. Processes and intermediates for preparing cis(+)3-[4,6-dihydroxy chroman-3-ylmethyl]-4-methoxyaniline

Also Published As

Publication number Publication date
HN1997000127A (es) 1997-12-20
EP0925292B1 (en) 2003-09-10
TNSN97155A1 (fr) 2005-03-15
TW449579B (en) 2001-08-11
NO991254D0 (no) 1999-03-15
DE69724801D1 (de) 2003-10-16
JP2000502726A (ja) 2000-03-07
EA002204B1 (ru) 2002-02-28
CA2265043C (en) 2003-01-14
BG63542B1 (bg) 2002-04-30
US20020042526A1 (en) 2002-04-11
YU13299A (sh) 2001-03-07
ZA978291B (en) 1999-03-15
DZ2308A1 (fr) 2002-12-28
US6096906A (en) 2000-08-01
GT199700104AA (es) 1999-03-28
TR199900592T2 (xx) 1999-06-21
ES2206738T3 (es) 2004-05-16
AU713701B2 (en) 1999-12-09
AU3781497A (en) 1998-04-02
ATE249452T1 (de) 2003-09-15
KR20000036136A (ko) 2000-06-26
PE109798A1 (es) 1999-01-13
SK31399A3 (en) 2000-05-16
NO991254L (no) 1999-05-14
UA58520C2 (uk) 2003-08-15
CO4600635A1 (es) 1998-05-08
IL128732A0 (en) 2000-01-31
US6444826B1 (en) 2002-09-03
IS4980A (is) 1999-02-16
NZ334214A (en) 2000-09-29
CA2265043A1 (en) 1998-03-19
JP3117730B2 (ja) 2000-12-18
DK0925292T3 (da) 2004-01-12
PT925292E (pt) 2004-01-30
GT199700104BA (es) 1999-03-28
DE69724801T2 (de) 2004-06-17
AP9701083A0 (en) 1997-10-31
ID19613A (id) 1998-07-23
CN1230954A (zh) 1999-10-06
EP0925292A1 (en) 1999-06-30
PA8437901A1 (es) 2000-05-24
HRP970497A2 (en) 1998-08-31
US6355825B1 (en) 2002-03-12
BR9711482A (pt) 1999-08-24
US6288242B1 (en) 2001-09-11
KR100339164B1 (ko) 2002-06-01
AP726A (en) 1999-01-29
PL332351A1 (en) 1999-09-13
EA199900204A1 (ru) 1999-08-26
OA10995A (en) 2001-11-06
HRP970497B1 (en) 2002-06-30
MA24319A1 (fr) 1998-04-01
CN1108298C (zh) 2003-05-14
GT199700104A (es) 1999-03-02
WO1998011085A1 (en) 1998-03-19
US20020099227A1 (en) 2002-07-25

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