BG102437A - Таблетки, съдържащи каптоприл - Google Patents
Таблетки, съдържащи каптоприлInfo
- Publication number
- BG102437A BG102437A BG102437A BG10243798A BG102437A BG 102437 A BG102437 A BG 102437A BG 102437 A BG102437 A BG 102437A BG 10243798 A BG10243798 A BG 10243798A BG 102437 A BG102437 A BG 102437A
- Authority
- BG
- Bulgaria
- Prior art keywords
- binder
- tablets
- substance
- captopril tablets
- captopril
- Prior art date
Links
- FAKRSMQSSFJEIM-RQJHMYQMSA-N captopril Chemical compound SC[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O FAKRSMQSSFJEIM-RQJHMYQMSA-N 0.000 title abstract 2
- 229960000830 captopril Drugs 0.000 title abstract 2
- 239000011230 binding agent Substances 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
- 239000001913 cellulose Substances 0.000 abstract 1
- 229920002678 cellulose Polymers 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- 239000000945 filler Substances 0.000 abstract 1
- 239000008101 lactose Substances 0.000 abstract 1
- 239000000314 lubricant Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/42—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of mineralocorticosteroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Compounds Of Unknown Constitution (AREA)
Abstract
Таблетките,съдържащи каптоприл са с повишена стабилност и производството им е улеснено. Стандартното отклонение на съдържанието на активния компонент в една таблетка, в половина или четвъртина от нея е многониско. Таблетките включват пълнител и свързващо вещество, разпадащо вещество и смазка и плъзгащо вещество. Пълнителят и свързващото вещество представляват смес от лактоза и микрокристална целулоза втегловни съотношения 1,5:1-1:1, която смес е от 60 до 80% тегл. от общото тегло на таблетката.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU9602470A HU222109B1 (hu) | 1996-09-10 | 1996-09-10 | Captopriltartalmú tabletták és eljárás ezek előállítására |
PCT/HU1997/000051 WO1998010753A1 (en) | 1996-09-10 | 1997-09-10 | Captopril tablets |
Publications (2)
Publication Number | Publication Date |
---|---|
BG102437A true BG102437A (bg) | 1999-01-29 |
BG63964B1 BG63964B1 (bg) | 2003-08-29 |
Family
ID=89994256
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG102437A BG63964B1 (bg) | 1996-09-10 | 1998-05-08 | Таблетки, съдържащи каптоприл |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0879050B1 (bg) |
JP (1) | JPH11513046A (bg) |
KR (1) | KR19990067412A (bg) |
AT (1) | ATE227981T1 (bg) |
AU (1) | AU4469097A (bg) |
BG (1) | BG63964B1 (bg) |
CZ (1) | CZ285771B6 (bg) |
DE (1) | DE69717253T2 (bg) |
EA (1) | EA000676B1 (bg) |
HU (1) | HU222109B1 (bg) |
PL (1) | PL189224B1 (bg) |
SK (1) | SK53798A3 (bg) |
UA (1) | UA64702C2 (bg) |
WO (1) | WO1998010753A1 (bg) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL197077B1 (pl) * | 1998-12-01 | 2008-02-29 | Reddys Lab Inc Dr | Kompozycja farmaceutyczna zawierająca 5-[[4-[3-metylo-4-okso-3,4-dihydro-2-chinazolinylo]metoksy]fenylometylo]-tiazolidyno-2,4-dion lub jego sól dopuszczalną do stosowania w farmacji i sposób jej wytwarzania |
JP2000273038A (ja) * | 1999-01-20 | 2000-10-03 | Taisho Pharmaceut Co Ltd | 口腔内溶解性錠剤 |
US7094545B2 (en) | 2003-04-30 | 2006-08-22 | Ferring Bv | Pharmaceutical composition as solid dosage form and method for manufacturing thereof |
EA011862B1 (ru) | 2004-03-24 | 2009-06-30 | Актавис Груп Хф. | Композиции рамиприла |
DE102009012788A1 (de) * | 2009-03-13 | 2010-09-30 | J. Rettenmaier & Söhne Gmbh + Co. Kg | Verpressbares Tablettenmaterial mit ölhaltigem Wirkstoff, Tablette sowie Verfahren und Vorrichtung zu deren Herstellung |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2021408A1 (en) * | 1989-08-31 | 1991-03-01 | Luana R. C. Moore | Method for treating hypermotility diseases of the bowel employing an ace inhibitor and formulation for use therein |
CA2026686A1 (en) * | 1989-10-30 | 1991-05-01 | Werner Tschollar | Method for preventing onset of type ii diabetes employing an ace inhibitor |
US5030648A (en) * | 1990-01-12 | 1991-07-09 | E. R. Squibb & Sons, Inc. | Combination and method for treating obsessive-compulsive disorder, and motor and phonic tics in Tourettes' syndrome using such combination |
US5158777A (en) * | 1990-02-16 | 1992-10-27 | E. R. Squibb & Sons, Inc. | Captopril formulation providing increased duration of activity |
-
1996
- 1996-09-10 HU HU9602470A patent/HU222109B1/hu active IP Right Grant
-
1997
- 1997-09-10 DE DE69717253T patent/DE69717253T2/de not_active Expired - Fee Related
- 1997-09-10 PL PL97327460A patent/PL189224B1/pl not_active IP Right Cessation
- 1997-09-10 KR KR1019980703422A patent/KR19990067412A/ko not_active Application Discontinuation
- 1997-09-10 CZ CZ981194A patent/CZ285771B6/cs not_active IP Right Cessation
- 1997-09-10 AT AT97943083T patent/ATE227981T1/de not_active IP Right Cessation
- 1997-09-10 EA EA199800406A patent/EA000676B1/ru not_active IP Right Cessation
- 1997-09-10 EP EP97943083A patent/EP0879050B1/en not_active Expired - Lifetime
- 1997-09-10 JP JP10513413A patent/JPH11513046A/ja active Pending
- 1997-09-10 WO PCT/HU1997/000051 patent/WO1998010753A1/en not_active Application Discontinuation
- 1997-09-10 AU AU44690/97A patent/AU4469097A/en not_active Abandoned
- 1997-10-09 UA UA98062965A patent/UA64702C2/uk unknown
- 1997-10-10 SK SK537-98A patent/SK53798A3/sk unknown
-
1998
- 1998-05-08 BG BG102437A patent/BG63964B1/bg unknown
Also Published As
Publication number | Publication date |
---|---|
ATE227981T1 (de) | 2002-12-15 |
UA64702C2 (uk) | 2004-03-15 |
WO1998010753A1 (en) | 1998-03-19 |
DE69717253T2 (de) | 2003-08-28 |
AU4469097A (en) | 1998-04-02 |
KR19990067412A (ko) | 1999-08-16 |
HUP9602470A3 (en) | 2001-12-28 |
CZ285771B6 (cs) | 1999-11-17 |
EA000676B1 (ru) | 2000-02-28 |
EP0879050B1 (en) | 2002-11-20 |
SK53798A3 (en) | 1998-12-02 |
PL189224B1 (pl) | 2005-07-29 |
DE69717253D1 (de) | 2003-01-02 |
EP0879050A1 (en) | 1998-11-25 |
CZ119498A3 (cs) | 1998-09-16 |
EA199800406A1 (ru) | 1998-12-24 |
JPH11513046A (ja) | 1999-11-09 |
HU9602470D0 (en) | 1996-10-28 |
HUP9602470A2 (hu) | 1998-05-28 |
HU222109B1 (hu) | 2003-04-28 |
PL327460A1 (en) | 1998-12-07 |
BG63964B1 (bg) | 2003-08-29 |
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