BE899247A - Derives de gonadoliberine contenant un groupe beta-aspartyle, procede pour leur preparation et preparations pharmaceutiques les contenant - Google Patents

Derives de gonadoliberine contenant un groupe beta-aspartyle, procede pour leur preparation et preparations pharmaceutiques les contenant

Info

Publication number
BE899247A
BE899247A BE1/10986A BE1010986A BE899247A BE 899247 A BE899247 A BE 899247A BE 1/10986 A BE1/10986 A BE 1/10986A BE 1010986 A BE1010986 A BE 1010986A BE 899247 A BE899247 A BE 899247A
Authority
BE
Belgium
Prior art keywords
beta
pharmaceutical preparations
preparation
aspartyl group
preparations containing
Prior art date
Application number
BE1/10986A
Other languages
English (en)
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of BE899247A publication Critical patent/BE899247A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/13—Luteinizing hormone-releasing hormone; related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention est relative à des dérivés de gonadolibérine contenant un groupe beta-aspartyle. Ces dérivés sont représentés par la formule générale : Glp(1)-His(2)-Trp(3)-Ser(4)-Tyr(5)-Asp(6)-X(7) -----------/--Leu(8)-Arg(9)-Pro(10)-Y . Préparations pharmaceutiques les contenant et exrçant un puissant effet sur le processus de la reproduction des vertèbres.
BE1/10986A 1983-03-29 1984-03-26 Derives de gonadoliberine contenant un groupe beta-aspartyle, procede pour leur preparation et preparations pharmaceutiques les contenant BE899247A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU831062A HU187503B (en) 1983-03-29 1983-03-29 Process for preparing gonadoliberine derivatives containing beta-aspartyl group

Publications (1)

Publication Number Publication Date
BE899247A true BE899247A (fr) 1984-09-26

Family

ID=10952693

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1/10986A BE899247A (fr) 1983-03-29 1984-03-26 Derives de gonadoliberine contenant un groupe beta-aspartyle, procede pour leur preparation et preparations pharmaceutiques les contenant

Country Status (22)

Country Link
US (1) US4600705A (fr)
JP (1) JPS59219259A (fr)
AR (1) AR240835A1 (fr)
AT (1) AT389704B (fr)
AU (1) AU558705B2 (fr)
BE (1) BE899247A (fr)
CA (1) CA1258150A (fr)
CH (1) CH664573A5 (fr)
DE (1) DE3411709A1 (fr)
DK (1) DK163247C (fr)
ES (2) ES8605823A1 (fr)
FI (1) FI82837C (fr)
FR (1) FR2543546B1 (fr)
GB (1) GB2138427B (fr)
GR (1) GR81935B (fr)
HU (1) HU187503B (fr)
IL (1) IL71380A (fr)
IT (1) IT1196064B (fr)
LU (1) LU85270A1 (fr)
NL (1) NL8400965A (fr)
SE (1) SE464814B (fr)
ZA (1) ZA842352B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3433010A (en) * 1966-01-19 1969-03-18 Sunbeam Corp Electric clock
HU189394B (en) * 1983-12-23 1986-06-30 Koezponti Valto- Es Hitelbank Rt Innovacios Alap,Hu Method for producing spermatozoa suitable for fertilization from mature fishes
US4677193A (en) * 1985-02-22 1987-06-30 The Salk Institute For Biological Studies Peptides containing an aliphatic-aromatic ketone side chain
HU194280B (en) * 1985-10-22 1988-01-28 Richter Gedeon Vegyeszet Process for producing new gonadoliberin analogues of high effectivity and pharmaceutical compositions containing them
GB9112825D0 (en) * 1991-06-14 1991-07-31 Ici Plc Process for making peptides

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2438350C3 (de) * 1974-08-09 1979-06-13 Hoechst Ag, 6000 Frankfurt Peptide mit starker LH-RH/FSH-RH-Wirkung, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE2617646C2 (de) * 1976-04-22 1986-07-31 Hoechst Ag, 6230 Frankfurt Nonapeptid-amide und Decapeptid-amide mit Gonadoliberin-Wirkung, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
DE3020941A1 (de) * 1980-06-03 1981-12-17 Hoechst Ag, 6000 Frankfurt Nonapeptid, verfahren zu seiner herstellung, dieses enthaltendes mittel und seine verwendung
US4410514A (en) * 1982-12-06 1983-10-18 The Salk Institute For Biological Studies GnRH Agonists

Also Published As

Publication number Publication date
AT389704B (de) 1990-01-25
IT8420286A0 (it) 1984-03-29
IL71380A (en) 1987-01-30
GB2138427A (en) 1984-10-24
GR81935B (fr) 1984-12-12
FI841245A0 (fi) 1984-03-28
CH664573A5 (de) 1988-03-15
JPS59219259A (ja) 1984-12-10
ES8605823A1 (es) 1986-04-01
ES8606882A1 (es) 1986-05-01
SE8401724L (sv) 1984-11-09
ZA842352B (en) 1984-11-28
AU2625584A (en) 1984-10-04
FR2543546B1 (fr) 1987-02-20
FI82837B (fi) 1991-01-15
SE8401724D0 (sv) 1984-03-28
SE464814B (sv) 1991-06-17
DK163247C (da) 1992-06-29
CA1258150A (fr) 1989-08-01
HU187503B (en) 1986-01-28
US4600705A (en) 1986-07-15
AR240835A2 (es) 1991-02-28
ES531071A0 (es) 1986-04-01
ATA106084A (de) 1989-06-15
DK171884A (da) 1984-09-30
FI82837C (fi) 1991-04-25
IL71380A0 (en) 1984-06-29
GB8408128D0 (en) 1984-05-10
ES544757A0 (es) 1986-05-01
DE3411709A1 (de) 1984-10-18
LU85270A1 (fr) 1985-10-14
AU558705B2 (en) 1987-02-05
GB2138427B (en) 1986-08-28
NL8400965A (nl) 1984-10-16
FI841245A (fi) 1984-09-30
AR240835A1 (es) 1991-02-28
DK171884D0 (da) 1984-03-28
DK163247B (da) 1992-02-10
IT1196064B (it) 1988-11-10
FR2543546A1 (fr) 1984-10-05

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: RICHTER GEDEON VEGYESZETI GYAR R.T.

Effective date: 19940331