FR2432498A1 - Nouveaux derives du pinene et leur preparation - Google Patents

Nouveaux derives du pinene et leur preparation

Info

Publication number
FR2432498A1
FR2432498A1 FR7919764A FR7919764A FR2432498A1 FR 2432498 A1 FR2432498 A1 FR 2432498A1 FR 7919764 A FR7919764 A FR 7919764A FR 7919764 A FR7919764 A FR 7919764A FR 2432498 A1 FR2432498 A1 FR 2432498A1
Authority
FR
France
Prior art keywords
new
preparation
pinene derivatives
derivatives
pinene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7919764A
Other languages
English (en)
Other versions
FR2432498B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yissum Research Development Co of Hebrew University of Jerusalem
Original Assignee
Yissum Research Development Co of Hebrew University of Jerusalem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Research Development Co of Hebrew University of Jerusalem filed Critical Yissum Research Development Co of Hebrew University of Jerusalem
Publication of FR2432498A1 publication Critical patent/FR2432498A1/fr
Application granted granted Critical
Publication of FR2432498B1 publication Critical patent/FR2432498B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
    • C07C39/17—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings containing other rings in addition to the six-membered aromatic rings, e.g. cyclohexylphenol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
    • C07C43/1788—Unsaturated ethers containing hydroxy or O-metal groups containing six-membered aromatic rings and other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Nouveaux dérivés du résorcinol substitué en position 2 par un radical dérivé du pinane. Ils sont représentés par la formule générale :
FR7919764A 1978-08-02 1979-08-01 Nouveaux derives du pinene et leur preparation Granted FR2432498A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL55274A IL55274A (en) 1978-08-02 1978-08-02 4-(2,6-dihydroxy-4-(dimethylheptyl)phenyl)substituted 2-pinen-10-ol and pinane derivatives,their preparation and pharmaceutical compositions comprising them

Publications (2)

Publication Number Publication Date
FR2432498A1 true FR2432498A1 (fr) 1980-02-29
FR2432498B1 FR2432498B1 (fr) 1984-09-21

Family

ID=11050472

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7919764A Granted FR2432498A1 (fr) 1978-08-02 1979-08-01 Nouveaux derives du pinene et leur preparation

Country Status (5)

Country Link
US (1) US4282248A (fr)
DE (1) DE2929517A1 (fr)
FR (1) FR2432498A1 (fr)
GB (1) GB2027021B (fr)
IL (1) IL55274A (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4886544A (en) * 1987-03-17 1989-12-12 Hayashi Sei Ichi 23-phenylbrassinosteroids
US4758597A (en) * 1987-05-15 1988-07-19 University Patents, Inc. Carenadiol and derivatives
US5434295A (en) * 1994-02-07 1995-07-18 Yissum Research Development Company Neuroprotective pharmaceutical compositions of 4-phenylpinene derivatives and certain novel 4-phenylpinene compounds
ATE247097T1 (de) * 1998-05-04 2003-08-15 Univ Connecticut Analgetische und immunomodulierende cannabinoiden
US7897598B2 (en) 1998-06-09 2011-03-01 Alexandros Makriyannis Inhibitors of the anandamide transporter
US7589220B2 (en) 1998-06-09 2009-09-15 University Of Connecticut Inhibitors of the anandamide transporter
US7276613B1 (en) 1998-11-24 2007-10-02 University Of Connecticut Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US7161016B1 (en) 1998-11-24 2007-01-09 University Of Connecticut Cannabimimetic lipid amides as useful medications
US6900236B1 (en) 1999-10-18 2005-05-31 University Of Connecticut Cannabimimetic indole derivatives
US7393842B2 (en) 2001-08-31 2008-07-01 University Of Connecticut Pyrazole analogs acting on cannabinoid receptors
EP1224155B1 (fr) * 1999-10-18 2007-02-21 The University Of Connecticut Nouveaux agonistes de cannabinoides bicycliques destines au recepteur de cannabinoides
US7119108B1 (en) 1999-10-18 2006-10-10 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US6943266B1 (en) * 1999-10-18 2005-09-13 University Of Connecticut Bicyclic cannabinoid agonists for the cannabinoid receptor
MXPA02005103A (es) 1999-10-18 2003-09-25 Alexipharma Inc Ligandos selectivos del receptor de canabinoide (cb2) perifericos.
US8084467B2 (en) 1999-10-18 2011-12-27 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US7741365B2 (en) 1999-10-18 2010-06-22 University Of Connecticut Peripheral cannabinoid receptor (CB2) selective ligands
IL132661A (en) * 1999-10-31 2008-11-26 Raphael Mechoulam Agonists specific for peripheral cannabinoid receptors
EP1361876A4 (fr) 2001-01-26 2004-03-31 Univ Connecticut Nouveaux ligands cannabimimetiques
US7173027B2 (en) 2001-01-29 2007-02-06 University Of Connecticut Receptor selective cannabimimetic aminoalkylindoles
CA2452881C (fr) 2001-07-13 2012-03-06 University Of Connecticut Nouveaux cannabinoides bicycliques et tricycliques
JP2005510492A (ja) 2001-10-26 2005-04-21 ユニバーシティ オブ コネチカット 新規な種類の効力のあるカンナビミメティックリガンド
IL150302A (en) * 2002-01-31 2008-07-08 Naim Menashe Bicyclic cb2 cannabinoid receptor ligands
IL147941A0 (en) * 2002-01-31 2002-08-14 Pharmos Corp Bicyclic cb2 cannabinoid receptor ligands
WO2003063758A2 (fr) * 2002-01-31 2003-08-07 Pharmos Corporation Ligands du recepteur cannabinoide cb2 bicyclique
WO2003091189A1 (fr) * 2002-04-25 2003-11-06 Virginia Commonwealth University Cannabinoides
CA2496097A1 (fr) 2002-08-23 2004-03-04 University Of Connecticut Ceto-cannabinoides possedant des indications therapeutiques
WO2005123053A2 (fr) * 2004-06-22 2005-12-29 Pharmos Limited Utilisation d'agonistes des recepteurs cb2 dans le traitement de la maladie d'huntington
ZA200703517B (en) * 2004-10-22 2008-08-27 Pharmos Corp Orally effective cannabinoid analogs
US20100004244A1 (en) * 2006-06-27 2010-01-07 Yissum Research Development Company Of The Hebrew University Of Jerusalem Use of cb2 receptor agonists for promoting neurogenesis
US9763894B2 (en) * 2006-12-05 2017-09-19 Virginia Commonwealth University Inflammation therapy
US9428431B2 (en) 2008-10-06 2016-08-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Compositions comprising CB receptor agonists, uses thereof and methods for their preparation
JP2023553335A (ja) 2020-11-24 2023-12-21 イッサム・リサーチ・ディベロップメント・カンパニー・オブ・ザ・ヘブルー・ユニバーシティ・オブ・エルサレム・リミテッド カンナビノイド誘導体、及び、炎症、疼痛又は肥満の治療におけるそれらの使用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1275883A (en) * 1969-03-27 1972-05-24 Little Inc A Alkyl resorcinols and derivatives thereof
US3856820A (en) * 1973-07-18 1974-12-24 Smithkline Corp 2-AMINOMETHYL DIBENZO (b,d) PYRANS
FR2361383A1 (fr) * 1976-01-12 1978-03-10 Yissum Res Dev Co Derives de tetrahydrocannabinols
FR2370742A1 (fr) * 1976-11-10 1978-06-09 Lilly Co Eli Preparation stereoselective d'hexahydro-dibenzopyranones et intermediaires appropries

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1275883A (en) * 1969-03-27 1972-05-24 Little Inc A Alkyl resorcinols and derivatives thereof
US3856820A (en) * 1973-07-18 1974-12-24 Smithkline Corp 2-AMINOMETHYL DIBENZO (b,d) PYRANS
FR2361383A1 (fr) * 1976-01-12 1978-03-10 Yissum Res Dev Co Derives de tetrahydrocannabinols
FR2370742A1 (fr) * 1976-11-10 1978-06-09 Lilly Co Eli Preparation stereoselective d'hexahydro-dibenzopyranones et intermediaires appropries

Also Published As

Publication number Publication date
GB2027021A (en) 1980-02-13
FR2432498B1 (fr) 1984-09-21
GB2027021B (en) 1983-04-27
US4282248A (en) 1981-08-04
DE2929517A1 (de) 1980-02-21
IL55274A0 (en) 1978-10-31
IL55274A (en) 1982-08-31

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