FR2369263A1 - Nouveaux derives de la piperidine - Google Patents

Nouveaux derives de la piperidine

Info

Publication number
FR2369263A1
FR2369263A1 FR7733339A FR7733339A FR2369263A1 FR 2369263 A1 FR2369263 A1 FR 2369263A1 FR 7733339 A FR7733339 A FR 7733339A FR 7733339 A FR7733339 A FR 7733339A FR 2369263 A1 FR2369263 A1 FR 2369263A1
Authority
FR
France
Prior art keywords
piperidine
new derivatives
new
derivatives
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7733339A
Other languages
English (en)
Other versions
FR2369263B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anphar SA
Original Assignee
Anphar SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anphar SA filed Critical Anphar SA
Publication of FR2369263A1 publication Critical patent/FR2369263A1/fr
Application granted granted Critical
Publication of FR2369263B1 publication Critical patent/FR2369263B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Nouveaux dérivés de la pipéridine, caractérisés en ce qu'ils ont pour formule générale :
FR7733339A 1976-10-29 1977-10-28 Nouveaux derives de la piperidine Granted FR2369263A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB45146/76A GB1586468A (en) 1976-10-29 1976-10-29 Piperidine derivatives

Publications (2)

Publication Number Publication Date
FR2369263A1 true FR2369263A1 (fr) 1978-05-26
FR2369263B1 FR2369263B1 (fr) 1980-06-13

Family

ID=10436065

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7733339A Granted FR2369263A1 (fr) 1976-10-29 1977-10-28 Nouveaux derives de la piperidine

Country Status (7)

Country Link
US (1) US4367232A (fr)
JP (1) JPS5377069A (fr)
CA (1) CA1095044A (fr)
DE (1) DE2747960A1 (fr)
ES (2) ES463633A1 (fr)
FR (1) FR2369263A1 (fr)
GB (1) GB1586468A (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2534255A1 (fr) * 1982-10-11 1984-04-13 Delalande Sa Nouveaux derives de la 4-aroylamino piperidine, leur procede de preparation et leur application en therapeutique
FR2546169A1 (fr) * 1983-05-20 1984-11-23 Delalande Sa N-oxydes de derives aminocycliques, leur procede de preparation et leur application en therapeutique
EP0468683A1 (fr) * 1990-07-27 1992-01-29 Zeneca Limited Acylamidobenzamides fongicides
EP0468682A1 (fr) * 1990-07-27 1992-01-29 Zeneca Limited Acylaminobenzamides fongicides, ainsi que leur production et utilisation
TR27569A (tr) * 1992-01-24 1995-06-13 Ici Plc Yeni fungisidal asilaminobenzamidler, bunlarin hazirlanis islemleri ve bitkilerdeki mantar enfeksiyonlariyla mücadelede kullanimlari.

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5137896A (en) * 1981-10-01 1992-08-11 Janssen Pharmaceutica N.V. N-(3-hydroxy-4-piperidinyl)benzamide derivatives
US4962115A (en) * 1981-10-01 1990-10-09 Janssen Pharmaceutica N.V. Novel N-(3-hydroxy-4-piperidinyl)benzamide derivatives
US5057525A (en) * 1981-10-01 1991-10-15 Janssen Pharmaceutica N.V. Novel N-(3-hydroxy-4-piperidinyl) benzamide derivatives
GB8527052D0 (en) * 1985-11-02 1985-12-04 Beecham Group Plc Compounds
FI95572C (fi) * 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
US5739135A (en) * 1993-09-03 1998-04-14 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5885983A (en) * 1996-05-10 1999-03-23 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5827875A (en) * 1996-05-10 1998-10-27 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5883109A (en) * 1996-07-24 1999-03-16 Bristol-Myers Squibb Company Method for lowering serum lipid levels employing an MTP inhibitor in combination with another cholesterol lowering drug
SE9902987D0 (sv) * 1999-08-24 1999-08-24 Astra Pharma Prod Novel compounds
KR20080059687A (ko) * 2000-03-06 2008-06-30 아카디아 파마슈티칼스 인코포레이티드 세로토닌 관련 질병의 치료에 사용되는 아자시클릭 화합물
AU2001254546A1 (en) * 2000-04-20 2001-11-07 Nps Allelix Corp. Aminopiperidines
GB0011838D0 (en) * 2000-05-17 2000-07-05 Astrazeneca Ab Chemical compounds
RU2286801C2 (ru) * 2001-05-01 2006-11-10 Институт Нефтехимического Синтеза Имени А.В. Топчиева Российской Академии Наук Двухфазные биоадгезионные композиции, абсорбирующие воду
JP4535728B2 (ja) * 2001-12-28 2010-09-01 アカディア ファーマシューティカルズ，インコーポレーテッド モノアミン受容体調節因子としてのスピロアザ環式化合物
US7538222B2 (en) * 2002-06-24 2009-05-26 Acadia Pharmaceuticals, Inc. N-substituted piperidine derivatives as serotonin receptor agents
CA2490397A1 (fr) * 2002-06-24 2003-12-31 Acadia Pharmaceuticals Inc. Derives de piperidine substitues en n en tant qu'agents recepteurs de la serotonine
US7253186B2 (en) * 2002-06-24 2007-08-07 Carl-Magnus Andersson N-substituted piperidine derivatives as serotonin receptor agents
MY139563A (en) * 2002-09-04 2009-10-30 Bristol Myers Squibb Co Heterocyclic aromatic compounds useful as growth hormone secretagogues
CN101780080B (zh) * 2003-01-16 2014-06-04 阿卡蒂亚药品公司 用于神经退行性疾病的治疗的选择性五羟色胺2a/2c受体反向激动剂
MX251840B (es) * 2003-02-10 2007-11-26 Nippon Catalytic Chem Ind Agente particulado que absorbe agua.
SE0301369D0 (sv) * 2003-05-09 2003-05-09 Astrazeneca Ab Chemical compounds
US20050261278A1 (en) 2004-05-21 2005-11-24 Weiner David M Selective serotonin receptor inverse agonists as therapeutics for disease
US7820695B2 (en) * 2004-05-21 2010-10-26 Acadia Pharmaceuticals, Inc. Selective serotonin receptor inverse agonists as therapeutics for disease
US7790899B2 (en) * 2004-09-27 2010-09-07 Acadia Pharmaceuticals, Inc. Synthesis of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and crystalline forms
CN101031548B (zh) * 2004-09-27 2011-04-06 阿卡蒂亚药品公司 N-(4-氟苄基)-n-(1-甲基哌啶-4-基)-n'-(4-(2-甲基丙氧基)-苯基甲基)脲的盐及其制备
EP1831165A1 (fr) * 2004-12-20 2007-09-12 F. Hoffmann-Roche AG Derives de 4-aminopiperidine
CN101677971A (zh) 2007-03-19 2010-03-24 阿卡蒂亚药品公司 5-ht2a反向激动剂和拮抗剂与抗精神病药物的组合
DK2200610T3 (en) * 2007-09-21 2018-04-23 Acadia Pharm Inc ADMINISTRATION OF PIMAVANSERIN WITH OTHER AGENTS
ES2890492T3 (es) 2015-07-20 2022-01-20 Acadia Pharm Inc Métodos para preparar N-(4-fluorobencil)-N-(1-metilpiperidin-4-il)-N'-(4-(2-metilpropiloxi)fenilmetil)carbamida y su sal de tartrato y forma polimórfica C
US10953000B2 (en) 2016-03-25 2021-03-23 Acadia Pharmaceuticals Inc. Combination of pimavanserin and cytochrome P450 modulators
WO2017165635A1 (fr) 2016-03-25 2017-09-28 Acadia Pharmaceuticals Inc. Association de pimavansérine et de modulateurs du cytochrome p450
WO2018118626A1 (fr) 2016-12-20 2018-06-28 Acadia Pharmaceuticals Inc. Pimavansérine seule ou en association pour une utilisation dans le traitement de la psychose liée à la maladie d'alzheimer
EP3615028A1 (fr) 2017-04-28 2020-03-04 Acadia Pharmaceuticals Inc. Pimavansérine pour le traitement d'un trouble de contrôle des impulsions
US20210077479A1 (en) 2017-08-30 2021-03-18 Acadia Pharmaceuticals Inc. Formulations of pimavanserin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2745837A (en) * 1954-01-21 1956-05-15 Schering Corp Benzhydryl ethers of alkyl piperidinols
NL270803A (fr) * 1960-11-09
US3342826A (en) * 1964-01-13 1967-09-19 Ile De France Heterocyclic aminoalkyl benzamides
US3963745A (en) * 1972-04-03 1976-06-15 A. H. Robins Company, Incorporated Method for controlling emesis with N-(1-substituted-3-pyrrolidinyl)benzamides and thiobenzamides
US3862139A (en) * 1972-06-23 1975-01-21 Delmar Chem Heterocyclic benzamide compounds
CA1046066A (fr) * 1973-08-23 1979-01-09 Tomio Muro (piperidino (et pyrrolidin -1-yl) methyle)-1 (phenoxyle substitue)-3 propanols-2
DE2513136C3 (de) 1974-03-21 1981-04-30 Anphar S.A., Madrid N-(1-Benzylpiperid-4-yl)-benzamide, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2534255A1 (fr) * 1982-10-11 1984-04-13 Delalande Sa Nouveaux derives de la 4-aroylamino piperidine, leur procede de preparation et leur application en therapeutique
FR2546169A1 (fr) * 1983-05-20 1984-11-23 Delalande Sa N-oxydes de derives aminocycliques, leur procede de preparation et leur application en therapeutique
EP0468683A1 (fr) * 1990-07-27 1992-01-29 Zeneca Limited Acylamidobenzamides fongicides
EP0468682A1 (fr) * 1990-07-27 1992-01-29 Zeneca Limited Acylaminobenzamides fongicides, ainsi que leur production et utilisation
TR25156A (tr) * 1990-07-27 1992-11-01 Ici Plc YENI FUNGISID TESIRLI ASILAMINOBENZAMIDLER, BUNLARIN HAZIRLANMASI ICIN ISLEMLER VE BUNLARIN BITKILERIN MANTAR ENFEKSIYONLARYLA MüCADELEDE KULLANIMI.
TR27569A (tr) * 1992-01-24 1995-06-13 Ici Plc Yeni fungisidal asilaminobenzamidler, bunlarin hazirlanis islemleri ve bitkilerdeki mantar enfeksiyonlariyla mücadelede kullanimlari.

Also Published As

Publication number Publication date
JPS5377069A (en) 1978-07-08
CA1095044A (fr) 1981-02-03
ES463633A1 (es) 1978-07-01
GB1586468A (en) 1981-03-18
DE2747960A1 (de) 1978-05-11
US4367232A (en) 1983-01-04
FR2369263B1 (fr) 1980-06-13
ES463632A1 (es) 1978-07-16

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