FR2543546B1 - Derives de gonadoreline contenant un groupe b-aspartyle, procede pour leur preparation et preparations pharmaceutiques les contenant - Google Patents

Derives de gonadoreline contenant un groupe b-aspartyle, procede pour leur preparation et preparations pharmaceutiques les contenant

Info

Publication number
FR2543546B1
FR2543546B1 FR8404845A FR8404845A FR2543546B1 FR 2543546 B1 FR2543546 B1 FR 2543546B1 FR 8404845 A FR8404845 A FR 8404845A FR 8404845 A FR8404845 A FR 8404845A FR 2543546 B1 FR2543546 B1 FR 2543546B1
Authority
FR
France
Prior art keywords
gonadorelin
preparation
pharmaceutical preparations
aspartyl group
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8404845A
Other languages
English (en)
Other versions
FR2543546A1 (fr
Inventor
Janos Seprodi
Istvan Teplan
Imre Mezo
Judit Erchegyi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of FR2543546A1 publication Critical patent/FR2543546A1/fr
Application granted granted Critical
Publication of FR2543546B1 publication Critical patent/FR2543546B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/13—Luteinizing hormone-releasing hormone; related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8404845A 1983-03-29 1984-03-28 Derives de gonadoreline contenant un groupe b-aspartyle, procede pour leur preparation et preparations pharmaceutiques les contenant Expired FR2543546B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU831062A HU187503B (en) 1983-03-29 1983-03-29 Process for preparing gonadoliberine derivatives containing beta-aspartyl group

Publications (2)

Publication Number Publication Date
FR2543546A1 FR2543546A1 (fr) 1984-10-05
FR2543546B1 true FR2543546B1 (fr) 1987-02-20

Family

ID=10952693

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8404845A Expired FR2543546B1 (fr) 1983-03-29 1984-03-28 Derives de gonadoreline contenant un groupe b-aspartyle, procede pour leur preparation et preparations pharmaceutiques les contenant

Country Status (22)

Country Link
US (1) US4600705A (fr)
JP (1) JPS59219259A (fr)
AR (1) AR240835A1 (fr)
AT (1) AT389704B (fr)
AU (1) AU558705B2 (fr)
BE (1) BE899247A (fr)
CA (1) CA1258150A (fr)
CH (1) CH664573A5 (fr)
DE (1) DE3411709A1 (fr)
DK (1) DK163247C (fr)
ES (2) ES8605823A1 (fr)
FI (1) FI82837C (fr)
FR (1) FR2543546B1 (fr)
GB (1) GB2138427B (fr)
GR (1) GR81935B (fr)
HU (1) HU187503B (fr)
IL (1) IL71380A (fr)
IT (1) IT1196064B (fr)
LU (1) LU85270A1 (fr)
NL (1) NL8400965A (fr)
SE (1) SE464814B (fr)
ZA (1) ZA842352B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3433010A (en) * 1966-01-19 1969-03-18 Sunbeam Corp Electric clock
HU189394B (en) * 1983-12-23 1986-06-30 Koezponti Valto- Es Hitelbank Rt Innovacios Alap,Hu Method for producing spermatozoa suitable for fertilization from mature fishes
US4677193A (en) * 1985-02-22 1987-06-30 The Salk Institute For Biological Studies Peptides containing an aliphatic-aromatic ketone side chain
HU194280B (en) * 1985-10-22 1988-01-28 Richter Gedeon Vegyeszet Process for producing new gonadoliberin analogues of high effectivity and pharmaceutical compositions containing them
GB9112825D0 (en) * 1991-06-14 1991-07-31 Ici Plc Process for making peptides

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2438350C3 (de) * 1974-08-09 1979-06-13 Hoechst Ag, 6000 Frankfurt Peptide mit starker LH-RH/FSH-RH-Wirkung, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE2617646C2 (de) * 1976-04-22 1986-07-31 Hoechst Ag, 6230 Frankfurt Nonapeptid-amide und Decapeptid-amide mit Gonadoliberin-Wirkung, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
DE3020941A1 (de) * 1980-06-03 1981-12-17 Hoechst Ag, 6000 Frankfurt Nonapeptid, verfahren zu seiner herstellung, dieses enthaltendes mittel und seine verwendung
US4410514A (en) * 1982-12-06 1983-10-18 The Salk Institute For Biological Studies GnRH Agonists

Also Published As

Publication number Publication date
HU187503B (en) 1986-01-28
ES8605823A1 (es) 1986-04-01
DK171884D0 (da) 1984-03-28
AU2625584A (en) 1984-10-04
ATA106084A (de) 1989-06-15
DK171884A (da) 1984-09-30
IT8420286A0 (it) 1984-03-29
LU85270A1 (fr) 1985-10-14
AR240835A1 (es) 1991-02-28
FI841245A (fi) 1984-09-30
DK163247C (da) 1992-06-29
SE8401724D0 (sv) 1984-03-28
IL71380A0 (en) 1984-06-29
DK163247B (da) 1992-02-10
US4600705A (en) 1986-07-15
FI82837B (fi) 1991-01-15
AT389704B (de) 1990-01-25
GB2138427B (en) 1986-08-28
GR81935B (fr) 1984-12-12
AU558705B2 (en) 1987-02-05
GB2138427A (en) 1984-10-24
IL71380A (en) 1987-01-30
IT1196064B (it) 1988-11-10
FI841245A0 (fi) 1984-03-28
BE899247A (fr) 1984-09-26
JPS59219259A (ja) 1984-12-10
SE464814B (sv) 1991-06-17
AR240835A2 (es) 1991-02-28
ZA842352B (en) 1984-11-28
CH664573A5 (de) 1988-03-15
DE3411709A1 (de) 1984-10-18
ES8606882A1 (es) 1986-05-01
FI82837C (fi) 1991-04-25
SE8401724L (sv) 1984-11-09
CA1258150A (fr) 1989-08-01
FR2543546A1 (fr) 1984-10-05
NL8400965A (nl) 1984-10-16
ES531071A0 (es) 1986-04-01
ES544757A0 (es) 1986-05-01
GB8408128D0 (en) 1984-05-10

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Legal Events

Date Code Title Description
ST Notification of lapse