US4126680A
(en)
*
|
1977-04-27 |
1978-11-21 |
Pfizer Inc. |
Tetracycline antibiotic compositions
|
EP0009559B1
(de)
*
|
1978-08-01 |
1982-08-25 |
Ciba-Geigy Ag |
Stabile flüssige Arzneimittelformulierung, ihre Herstellung und Verwendung
|
EP0012496B1
(en)
*
|
1978-12-08 |
1983-07-20 |
Beecham Group Plc |
A process for the preparation of a solid sodium amoxycillin and aqueous solutions thereof
|
US4259331A
(en)
*
|
1979-04-16 |
1981-03-31 |
Pfizer Inc. |
Oxytetracycline compositions
|
DE3064250D1
(en)
*
|
1979-07-02 |
1983-08-25 |
Pfizer |
Long acting sulfonamide injectable compositions
|
DE3063763D1
(en)
*
|
1979-07-05 |
1983-07-21 |
Pfizer |
Sulfonamide solutions
|
US4303643A
(en)
*
|
1979-07-05 |
1981-12-01 |
Pfizer Inc. |
Sulfonamide compositions
|
US4386083A
(en)
*
|
1980-04-10 |
1983-05-31 |
Walter Hacke |
Injectable oxytetracycline compositions
|
US4399127A
(en)
*
|
1980-04-10 |
1983-08-16 |
Diamond Shamrock Corporation |
Injectable oxytetracycline compositions
|
CA1163197A
(en)
*
|
1980-04-10 |
1984-03-06 |
Herman Horn |
Injectable oxytetracycline compositions
|
US4374826A
(en)
*
|
1980-07-21 |
1983-02-22 |
Pfizer Inc. |
Sulfonamide compositions
|
NL178941C
(nl)
*
|
1982-06-15 |
1986-06-16 |
Aesculaap Bv |
Werkwijze voor de bereiding van een waterig oxytetracyclinepreparaat.
|
US4769232A
(en)
*
|
1984-03-22 |
1988-09-06 |
Pfizer Inc. |
Parenteral formulations of indolmycin
|
IE74244B1
(en)
*
|
1985-10-01 |
1997-07-16 |
Bimeda Res Dev Ltd |
A process for preparing an antibiotic composition
|
HU194493B
(en)
*
|
1985-11-27 |
1988-02-29 |
Chinoin Gyogyszer Es Vegyeszet |
Process for preparing primycin-containing colloidal basic gel and compositions comprising the same
|
FR2608044B1
(fr)
*
|
1986-12-10 |
1992-09-11 |
Sogeval |
Composition antibiotique aqueuse a usage veterinaire
|
US4906475A
(en)
*
|
1988-02-16 |
1990-03-06 |
Paco Pharmaceutical Services |
Estradiol transdermal delivery system
|
US6756365B2
(en)
*
|
1991-11-06 |
2004-06-29 |
Trustees Of Tufts College |
Reducing tetracycline resistance in living cells
|
EP0626171A1
(de)
*
|
1993-05-26 |
1994-11-30 |
Winfried Dörnhöfer |
Injektionslösung für die intravenöse oder intramuskuläre Verabreichung an Tiere
|
ES2130069B1
(es)
*
|
1997-04-10 |
2000-03-01 |
Basf Labiana S A |
Preparacion farmaceutica con liberacion retardada del producto activo.
|
US20020077276A1
(en)
*
|
1999-04-27 |
2002-06-20 |
Fredeking Terry M. |
Compositions and methods for treating hemorrhagic virus infections and other disorders
|
EP2327687A3
(en)
|
1999-09-14 |
2012-08-15 |
Trustees Of Tufts College |
Methods of preparing substituted tetracyclines with transition metal-based chemistries
|
US6849615B2
(en)
|
1999-09-14 |
2005-02-01 |
Paratek Pharmaceuticals, Inc. |
13-substituted methacycline compounds
|
US8106225B2
(en)
*
|
1999-09-14 |
2012-01-31 |
Trustees Of Tufts College |
Methods of preparing substituted tetracyclines with transition metal-based chemistries
|
US6500812B2
(en)
|
1999-09-14 |
2002-12-31 |
Paratek Pharmaceuticals, Inc. |
13-substituted methacycline compounds
|
AU2001228454A1
(en)
*
|
2000-01-13 |
2001-07-24 |
Merck Patent G.M.B.H |
Pharmaceutical preparations containing 2-pyrrolidone as the dissolving intermediary
|
EP1263442A1
(en)
|
2000-01-24 |
2002-12-11 |
Trustees Of Tufts College |
TETRACYCLINE COMPOUNDS FOR TREATMENT OF i CRYPTOSPORIDIUM PARVUM /i RELATED DISORDERS
|
AU2001251157A1
(en)
*
|
2000-03-31 |
2001-10-15 |
Paratek Pharmaceuticals, Inc |
7-and 9-carbamate, urea, thiourea, thiocarbamate, and heteroaryl-amino substituted tetracycline compounds
|
DE60102815D1
(de)
*
|
2000-05-15 |
2004-05-19 |
Paratek Pharm Innc |
7-substituierte kondensierte ring-tetrazyclin- verbindungen
|
US20020128238A1
(en)
*
|
2000-06-16 |
2002-09-12 |
Nelson Mark L. |
7-phenyl-substituted tetracycline compounds
|
US20020132798A1
(en)
*
|
2000-06-16 |
2002-09-19 |
Nelson Mark L. |
7-phenyl-substituted tetracycline compounds
|
US20040224927A1
(en)
*
|
2000-06-16 |
2004-11-11 |
Trustees Of Tufts College |
7-N-substituted phenyl tetracycline compounds
|
CA2415086A1
(en)
|
2000-07-07 |
2002-01-17 |
Trustees Of Tufts College |
7,8 and 9-substituted tetracycline compounds
|
CA2415172A1
(en)
|
2000-07-07 |
2002-01-17 |
Mark L. Nelson |
13-substituted methacycline compounds
|
US7094806B2
(en)
*
|
2000-07-07 |
2006-08-22 |
Trustees Of Tufts College |
7, 8 and 9-substituted tetracycline compounds
|
KR100619637B1
(ko)
*
|
2000-07-07 |
2006-09-12 |
트러스티즈 오브 터프츠 칼리지 |
7-치환 테트라사이클린 화합물
|
US20050143353A1
(en)
*
|
2000-07-07 |
2005-06-30 |
Paratek Pharmaceuticals, Inc. |
13-Substituted methacycline compounds
|
AU8638801A
(en)
|
2000-07-07 |
2002-01-21 |
Tufts College |
9-substituted minocycline compounds
|
RU2178698C1
(ru)
*
|
2000-11-28 |
2002-01-27 |
Закрытое Акционерное Общество "Нита-Фарм" |
Способ получения композиции магниевого комплекса окситетрациклина пролонгированного действия
|
US7553828B2
(en)
*
|
2001-03-13 |
2009-06-30 |
Paratek Pharmaceuticals, Inc. |
9-aminomethyl substituted minocycline compounds
|
WO2002072506A2
(en)
|
2001-03-13 |
2002-09-19 |
Paratek Pharmaceuticals, Inc. |
7-pyrollyl tetracycline compounds and methods of use thereof
|
EP1241160A1
(en)
*
|
2001-03-13 |
2002-09-18 |
Glaxo Group Limited |
Tetracycline derivatives and their use as antibiotic agents
|
CA2440383C
(en)
|
2001-03-13 |
2007-01-30 |
Paratek Pharmaceuticals, Inc. |
7,9-substituted tetracycline compounds
|
JP2005504722A
(ja)
|
2001-03-14 |
2005-02-17 |
パラテック ファーマシューティカルズ インコーポレイテッド |
相乗的抗真菌薬剤としての置換テトラサイクリン化合物
|
EP1379255A2
(en)
*
|
2001-03-14 |
2004-01-14 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds as antifungal agents
|
ES2338994T3
(es)
|
2001-04-24 |
2010-05-14 |
Paratek Pharmaceuticals, Inc. |
Compuestos de tetraciclina sustituida para el tratamiento de la malaria.
|
US8088820B2
(en)
*
|
2001-04-24 |
2012-01-03 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds for the treatment of malaria
|
US20030181371A1
(en)
*
|
2001-12-28 |
2003-09-25 |
Angiotech Pharmaceuticals, Inc. |
Compositions and methods of using collajolie
|
EP1474380A4
(en)
|
2002-01-08 |
2007-04-18 |
Paratek Pharm Innc |
4-DESDIMETHYL AMINO TETRA CYCLINE COMPOUNDS
|
CN102531948A
(zh)
|
2002-03-08 |
2012-07-04 |
帕拉特克药品公司 |
氨基-甲基取代的四环素类化合物
|
CN1653037A
(zh)
|
2002-03-21 |
2005-08-10 |
帕拉特克药品公司 |
取代的四环素化合物
|
US6958161B2
(en)
|
2002-04-12 |
2005-10-25 |
F H Faulding & Co Limited |
Modified release coated drug preparation
|
EA012136B1
(ru)
|
2002-07-12 |
2009-08-28 |
Пэрэтек Фамэсьютикэлс, Инк. |
Замещенные соединения тетрациклина, фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния у субъекта
|
CA2502464A1
(en)
|
2002-10-24 |
2004-05-06 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds for the treatment of malaria
|
AU2003300379A1
(en)
*
|
2002-12-27 |
2004-07-29 |
Angiotech Pharmaceuticals, Inc. |
Compositions and methods of using collagen and MMPI
|
CA2531732C
(en)
|
2003-07-09 |
2012-04-10 |
Paratek Pharmaceuticals, Inc. |
Prodrugs of 9-aminomethyl tetracycline compounds
|
EA200600221A1
(ru)
|
2003-07-09 |
2006-06-30 |
Пэрэтек Фамэсьютикэлс, Инк. |
Замещённые соединения тетрациклина (варианты), фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния у субъекта
|
US20060287283A1
(en)
*
|
2003-07-09 |
2006-12-21 |
Paratek Pharmaceuticals, Inc. |
Prodrugs of 9-aminomethyl tetracycline compounds
|
CN103040773A
(zh)
*
|
2003-07-25 |
2013-04-17 |
沃纳奇尔科特有限责任公司 |
多西环素金属络合物固体剂型
|
EP1716101A1
(en)
*
|
2004-01-15 |
2006-11-02 |
Paratek Pharmaceuticals, Inc. |
Aromatic a-ring derivatives of tetracycline compounds
|
TWI261038B
(en)
*
|
2004-08-11 |
2006-09-01 |
Bo-Cheng Chen |
Bicycle gear-shifting handgrip
|
EP2287140A3
(en)
|
2004-10-25 |
2011-09-21 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds
|
EP2301916A3
(en)
|
2004-10-25 |
2011-09-28 |
Paratek Pharmaceuticals, Inc. |
4-aminotetracyclines and methods of use thereof
|
AU2006206359B2
(en)
*
|
2005-01-21 |
2011-03-31 |
Allergan Pharmaceuticals International Limited |
A tetracycline metal complex in a solid dosage form
|
CA2597212A1
(en)
|
2005-02-04 |
2006-08-10 |
Paratek Pharmaceuticals, Inc. |
11a, 12-derivatives of tetracycline compounds
|
US20080242642A1
(en)
*
|
2007-04-02 |
2008-10-02 |
Medicis Pharmaceutical Corporation |
Minocycline oral dosage forms for the treatment of acne
|
US9192615B2
(en)
|
2008-08-06 |
2015-11-24 |
Medicis Pharmaceutical Corporation |
Method for the treatment of acne and certain dosage forms thereof
|
US7919483B2
(en)
*
|
2005-06-24 |
2011-04-05 |
Medicis Pharmaceutical Corporation |
Method for the treatment of acne
|
US7541347B2
(en)
*
|
2007-04-02 |
2009-06-02 |
Medicis Pharmaceutical Coropration |
Minocycline oral dosage forms for the treatment of acne
|
US7544373B2
(en)
*
|
2007-04-02 |
2009-06-09 |
Medicis Pharmaceutical Corporation |
Minocycline oral dosage forms for the treatment of acne
|
US20080241235A1
(en)
*
|
2007-04-02 |
2008-10-02 |
Medicis Pharmaceutical Corporation |
Minocycline oral dosage forms for the treatment of acne
|
US8252776B2
(en)
|
2007-04-02 |
2012-08-28 |
Medicis Pharmaceutical Corporation |
Minocycline oral dosage forms for the treatment of acne
|
US8722650B1
(en)
|
2005-06-24 |
2014-05-13 |
Medicis Pharmaceutical Corporation |
Extended-release minocycline dosage forms
|
JP2009502809A
(ja)
*
|
2005-07-21 |
2009-01-29 |
パラテック ファーマシューティカルズ インコーポレイテッド |
10−置換テトラサイクリンおよびその使用方法
|
US9078811B2
(en)
*
|
2006-01-24 |
2015-07-14 |
Paratek Pharmaceuticals, Inc. |
Methods of increasing oral bioavailability of tetracyclines
|
EP2007713A2
(en)
*
|
2006-04-17 |
2008-12-31 |
Teva Pharmaceutical Industries Ltd |
Isolation of tetracycline derivatives
|
US8198470B2
(en)
*
|
2006-04-24 |
2012-06-12 |
Teva Pharmaceutical Industries Ltd. |
Crystalline form II of tigecycline and processes for preparation thereof
|
CA2649075A1
(en)
*
|
2006-04-24 |
2007-11-08 |
Teva Pharmaceutical Industries Ltd. |
Tigeycline crystalline forms and processes for preparation thereof
|
EP2029749A2
(en)
*
|
2006-05-15 |
2009-03-04 |
Paratek Pharmaceuticals, Inc. |
Methods of regulating expression of genes or of gene products using substituted tetracycline compounds
|
US8440646B1
(en)
|
2006-10-11 |
2013-05-14 |
Paratek Pharmaceuticals, Inc. |
Substituted tetracycline compounds for treatment of Bacillus anthracis infections
|
PL2120963T3
(pl)
|
2006-12-21 |
2019-05-31 |
Paratek Pharm Innc |
Podstawione związki tetracyklinowe do leczenia zaburzeń zapalnych skóry
|
IL302749A
(en)
|
2006-12-21 |
2023-07-01 |
Paratek Pharm Innc |
A tetracycline compound, a pharmaceutical composition comprising the tetracycline compound, and the tetracycline compound of the pharmaceutical composition for treating a tetracycline responsive state
|
US20080241197A1
(en)
*
|
2007-04-02 |
2008-10-02 |
Medicis Pharmaceutical Corporation |
Minocycline dosage forms for the treatment of acne
|
AU2008239606A1
(en)
|
2007-04-12 |
2008-10-23 |
Paratek Pharmaceuticals, Inc. |
Methods for treating spinal muscular atrophy using tetracycline compounds
|
WO2008134048A2
(en)
*
|
2007-04-27 |
2008-11-06 |
Paratek Pharmaceuticals, Inc. |
Methods for synthesizing and purifying aminoalkyl tetracycline compounds
|
EP2192111A3
(en)
|
2007-07-06 |
2010-10-06 |
Paratek Pharmaceuticals, Inc. |
Methods for synthesizing substituted tetracycline compounds
|
KR20100126469A
(ko)
*
|
2008-03-05 |
2010-12-01 |
파라테크 파마슈티컬스, 인크. |
미노사이클린 화합물 및 이들의 사용 방법
|
PT2271348T
(pt)
|
2008-03-28 |
2018-04-16 |
Paratek Pharm Innc |
Formulação de comprimido oral de composto de tetraciclina
|
US20100022483A1
(en)
*
|
2008-04-14 |
2010-01-28 |
Paratek Pharmaceuticals, Inc. |
Substituted Tetracycline Compounds
|
TWI680117B
(zh)
|
2008-05-19 |
2019-12-21 |
派洛泰克藥物股份有限公司 |
四環素化合物之甲苯磺酸鹽及同素異形體
|
EA201170425A1
(ru)
*
|
2008-09-19 |
2011-10-31 |
Паратек Фармасьютикалс, Инк. |
Тетрациклиновые соединения для лечения ревматоидного артрита и связанные с ними способы лечения
|
AU2010233089B2
(en)
|
2009-04-10 |
2016-05-26 |
Tufts Medical Center, Inc. |
Par-1 activation by metalloproteinase-1 (MMP-1)
|
EP2568987B1
(en)
|
2010-05-12 |
2016-11-16 |
Rempex Pharmaceuticals, Inc. |
Tetracycline compositions
|
US9255068B2
(en)
|
2011-05-12 |
2016-02-09 |
Warner Chilcott Company, Llc |
Crystalline salts of (4S,4AS,5AR,12AS)-4-dimethylamino-3,10,12,12A-tetrahydroxy-7-[methoxy(methyl)amino)-methyl] acid amide and methods of using the same
|
US9561241B1
(en)
|
2011-06-28 |
2017-02-07 |
Medicis Pharmaceutical Corporation |
Gastroretentive dosage forms for minocycline
|
WO2015021387A2
(en)
*
|
2013-08-09 |
2015-02-12 |
Britt George N |
Formulations for control and prevention of periodontal and perimplant diseases and other diseases and conditions of the mouth, and supra and sub-gingival delivery methods and systems for such formulations
|
CN103536530A
(zh)
*
|
2013-10-30 |
2014-01-29 |
王玉万 |
盐酸多西环素长效注射剂及制备方法
|
EP3273940B1
(en)
|
2015-03-23 |
2020-12-16 |
Biopharmx, Inc. |
Pharmaceutical tetracycline composition for dermatological use
|
CN104721133B
(zh)
*
|
2015-04-14 |
2018-05-18 |
四川美嘉龙生物科技有限公司 |
一种土霉素制剂及制备方法
|
CA3042514A1
(en)
|
2016-11-01 |
2018-05-11 |
Paratek Pharmaceuticals, Inc. |
9-aminomethyl minocycline compounds and use thereof in treating community-acquired bacterial pneumonia (cabp)
|
WO2019016609A1
(en)
|
2017-07-21 |
2019-01-24 |
Allergan Pharmaceuticals International Limited |
TREATMENT OF NON-INFLAMMATORY LESIONS
|
AU2018374490B2
(en)
|
2017-11-28 |
2024-05-16 |
New Matterhorn, Llc |
Method for producing trehalose employing a trehalose phosphorylase variant
|
US11426351B2
(en)
|
2019-12-26 |
2022-08-30 |
Sunstar Inc. |
Process for producing a pharmaceutical composition containing micro particles
|