BE848371A - Benzisothiazolones et leurs sels pharmaceutiquement acceptables propres a la prophylaxie et au traitement de la thrombose, - Google Patents

Benzisothiazolones et leurs sels pharmaceutiquement acceptables propres a la prophylaxie et au traitement de la thrombose,

Info

Publication number
BE848371A
BE848371A BE172385A BE172385A BE848371A BE 848371 A BE848371 A BE 848371A BE 172385 A BE172385 A BE 172385A BE 172385 A BE172385 A BE 172385A BE 848371 A BE848371 A BE 848371A
Authority
BE
Belgium
Prior art keywords
benzisothiazolones
thrombosis
prophylaxis
treatment
pharmaceutically acceptable
Prior art date
Application number
BE172385A
Other languages
English (en)
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE848371A publication Critical patent/BE848371A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
BE172385A 1975-11-18 1976-11-16 Benzisothiazolones et leurs sels pharmaceutiquement acceptables propres a la prophylaxie et au traitement de la thrombose, BE848371A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4737375 1975-11-18

Publications (1)

Publication Number Publication Date
BE848371A true BE848371A (fr) 1977-05-16

Family

ID=10444739

Family Applications (1)

Application Number Title Priority Date Filing Date
BE172385A BE848371A (fr) 1975-11-18 1976-11-16 Benzisothiazolones et leurs sels pharmaceutiquement acceptables propres a la prophylaxie et au traitement de la thrombose,

Country Status (28)

Country Link
US (5) US4113728A (bs)
JP (1) JPS5262273A (bs)
AR (3) AR217411A1 (bs)
AT (1) AT355017B (bs)
AU (2) AU504599B2 (bs)
BE (1) BE848371A (bs)
BG (4) BG24808A3 (bs)
CA (1) CA1064511A (bs)
CH (1) CH627465A5 (bs)
CS (4) CS192593B2 (bs)
DD (1) DD127645A5 (bs)
DE (1) DE2652201A1 (bs)
DK (1) DK517776A (bs)
ES (3) ES453420A1 (bs)
FI (1) FI763285A (bs)
FR (1) FR2332019A1 (bs)
HU (1) HU173958B (bs)
IL (1) IL50690A (bs)
NL (1) NL7612796A (bs)
NO (1) NO763922L (bs)
NZ (1) NZ182325A (bs)
PH (1) PH13918A (bs)
PL (1) PL193742A1 (bs)
PT (1) PT65851B (bs)
RO (4) RO75777A (bs)
SE (1) SE7612919L (bs)
SU (4) SU682129A3 (bs)
ZA (1) ZA766489B (bs)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ182325A (en) * 1975-11-18 1979-03-16 Beecham Group Ltd 2-substituted-1,2-benzisothiazol-3-ones
US4190663A (en) * 1976-01-24 1980-02-26 Bayer Aktiengesellschaft Anti-thrombotic 1,2-benzisothiazolin-3-ones
DE2602643C2 (de) * 1976-01-24 1984-12-20 Bayer Ag, 5090 Leverkusen 1,2-Benzisothiazolinone-3, Verfahren zu ihrer Herstellung sowie Arzneimittel
EP0000254B1 (en) * 1977-06-20 1981-06-10 Beecham Group Plc Antithrombotic 2-(gamma-(1-piperidinyl)propyl)1,2-benzisothiazol 3-one, its pharmaceutically acceptable acid addition salts, their preparation and their compositions
DE2860430D1 (en) * 1977-10-08 1981-02-26 Beecham Group Ltd Antithrombotic compositions containing benzisothiazolones
ATE7296T1 (de) * 1979-10-08 1984-05-15 Merck & Co. Inc. 2-aryl-1,2-benzisothiazolinon-1,1-dioxide und sie enthaltende pharmazeutische zusammensetzungen.
DE3226284A1 (de) * 1982-07-14 1984-01-19 A. Nattermann & Cie GmbH, 5000 Köln Neue benzisoselenazolone, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3238006A1 (de) * 1982-10-13 1984-04-19 Bayer Ag, 5090 Leverkusen Azolyl-methylamine, ihre herstellung und verwendung in mikrobiziden mitteln
DE3500577A1 (de) * 1985-01-10 1986-07-10 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von 1,2-benzisothiazolonen
US4732984A (en) * 1985-10-17 1988-03-22 American Home Products Corporation Piperazinoisothiazolones with psychotropic activity
DE3617976A1 (de) * 1986-05-28 1988-01-14 Alter Sa 1,4-dihydropyridin, verfahren zu dessen herstellung und dessen verwendung in antithrombotischen medikamenten
US4831031A (en) * 1988-01-22 1989-05-16 Pfizer Inc. Aryl piperazinyl-(C2 or C4) alkylene heterocyclic compounds having neuroleptic activity
CA1340759C (en) * 1988-07-01 1999-09-21 James P. Albarella Isobenzothiazolone chromogenic thiol indicators and their derivatives
US5128457A (en) * 1988-07-01 1992-07-07 Miles Inc. Chromogenic thiol indicators based on an isobenzothiazolone ring system
US5236917A (en) * 1989-05-04 1993-08-17 Sterling Winthrop Inc. Saccharin derivatives useful as proteolytic enzyme inhibitors and compositions and method of use thereof
WO2010039545A2 (en) * 2008-09-23 2010-04-08 Georgetown University 1,2-benzisothiazolinone and isoindolinone derivatives
US9428472B2 (en) 2011-08-16 2016-08-30 Georgetown University Methods of treating bacterial infections with 1,2-benzisothiazolinone and isoindolinone derivatives
WO2017070157A1 (en) * 2015-10-19 2017-04-27 Emory University Redox dehydration coupling catalysts and methods related thereto

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE565380A (bs) * 1957-03-08
US3012039A (en) * 1958-03-14 1961-12-05 Ici Ltd 2-p-chlorobenzyl-1, 2-benzisothiazolone
DE1147947B (de) * 1961-07-25 1963-05-02 Knoll Ag Verfahren zur Herstellung neuer 1, 2-Benzisothiazolone
SE392103B (sv) * 1970-04-27 1977-03-14 Sherwin Williams Co Sett att framstella 1,2-bensisotiazolin-3-oner
US3661974A (en) * 1970-04-27 1972-05-09 Sherwin Williams Co 2-carbalkoxy-phenyl sulfenamides
NZ182325A (en) * 1975-11-18 1979-03-16 Beecham Group Ltd 2-substituted-1,2-benzisothiazol-3-ones
GB1582214A (en) * 1977-05-31 1981-01-07 Beecham Group Ltd Antithrombotic compositions
DE2734882A1 (de) * 1977-08-03 1979-02-22 Basf Ag 3- eckige klammer auf 4-(1,3-diazacycloalken-2-yl)-phenyl eckige klammer zu -1,2-benzisothiazole, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
CS192592B2 (en) 1979-08-31
FR2332019B1 (bs) 1983-05-20
US4113728A (en) 1978-09-12
AU520890B2 (en) 1982-03-04
AR215271A1 (es) 1979-09-28
RO75777A (ro) 1981-02-28
SU682129A3 (ru) 1979-08-25
NO763922L (bs) 1977-05-20
ATA849176A (de) 1979-07-15
RO75540A (ro) 1980-11-30
NL7612796A (nl) 1977-05-23
IL50690A (en) 1980-01-31
SU671728A3 (ru) 1979-06-30
ES453420A1 (es) 1978-02-16
RO75730A (ro) 1981-02-28
FI763285A (bs) 1977-05-19
US4243669A (en) 1981-01-06
AU1916376A (en) 1978-05-04
CS192594B2 (en) 1979-08-31
CS192593B2 (en) 1979-08-31
BG24809A3 (en) 1978-05-12
JPS5262273A (en) 1977-05-23
SU701536A3 (ru) 1979-11-30
DK517776A (da) 1977-05-19
RO69608A (ro) 1982-07-06
US4212872A (en) 1980-07-15
AR217411A1 (es) 1980-03-31
AT355017B (de) 1980-02-11
CH627465A5 (de) 1982-01-15
AU504599B2 (en) 1979-10-18
IL50690A0 (en) 1976-12-31
AR217449A1 (es) 1980-03-31
ES465173A1 (es) 1978-10-01
SU679141A3 (ru) 1979-08-05
ES465174A1 (es) 1978-10-01
SE7612919L (sv) 1977-05-19
NZ182325A (en) 1979-03-16
PT65851B (en) 1978-05-15
BG24810A3 (en) 1978-05-12
AU4716379A (en) 1979-09-27
DE2652201A1 (de) 1977-06-02
US4350702A (en) 1982-09-21
BG24808A3 (en) 1978-05-12
DD127645A5 (bs) 1977-10-05
ZA766489B (en) 1977-10-26
US4212979A (en) 1980-07-15
CA1064511A (en) 1979-10-16
FR2332019A1 (fr) 1977-06-17
PT65851A (en) 1976-12-01
HU173958B (hu) 1979-09-28
PL193742A1 (pl) 1979-05-21
BG24811A3 (en) 1978-05-12
PH13918A (en) 1980-11-04
CS192570B2 (en) 1979-08-31

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: BEECHAM GROUP LTD

Effective date: 19841116