BE826260A - Werkwijze voor het bereiden van werkzame cyclohexanolderivaten en van preparaten, die deze bevatten - Google Patents
Werkwijze voor het bereiden van werkzame cyclohexanolderivaten en van preparaten, die deze bevattenInfo
- Publication number
- BE826260A BE826260A BE153975A BE153975A BE826260A BE 826260 A BE826260 A BE 826260A BE 153975 A BE153975 A BE 153975A BE 153975 A BE153975 A BE 153975A BE 826260 A BE826260 A BE 826260A
- Authority
- BE
- Belgium
- Prior art keywords
- procedure
- preparation
- preparations containing
- cyclohexanol derivatives
- active
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US44780474A | 1974-03-04 | 1974-03-04 | |
US05/545,074 US3974157A (en) | 1974-03-04 | 1975-01-29 | 1-(Amino-alkyl)-2-aryl-cyclohexane alcohols and esters |
Publications (1)
Publication Number | Publication Date |
---|---|
BE826260A true BE826260A (nl) | 1975-06-30 |
Family
ID=27035098
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE153975A BE826260A (nl) | 1974-03-04 | 1975-03-04 | Werkwijze voor het bereiden van werkzame cyclohexanolderivaten en van preparaten, die deze bevatten |
Country Status (13)
Country | Link |
---|---|
US (1) | US3974157A (es) |
JP (1) | JPS50157342A (es) |
BE (1) | BE826260A (es) |
CH (4) | CH621329A5 (es) |
DK (2) | DK143698C (es) |
FI (1) | FI60205C (es) |
FR (1) | FR2262974B1 (es) |
GB (1) | GB1474004A (es) |
IE (1) | IE40733B1 (es) |
LU (1) | LU71964A1 (es) |
NL (1) | NL7502450A (es) |
NO (1) | NO140100C (es) |
SE (2) | SE7502407L (es) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10968209B2 (en) | 2016-05-19 | 2021-04-06 | Glaxosmithkline Intellectual Property (No.2) Limited | TRPV4 antagonist |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4115589A (en) * | 1977-05-17 | 1978-09-19 | The Upjohn Company | Compounds, compositions and method of use |
US4306097A (en) * | 1977-09-13 | 1981-12-15 | Pfizer Inc. | 3-[2-Hydroxy-4-(substituted)phenyl]-cycloalkanol analgesic agents |
US4366172A (en) * | 1977-09-29 | 1982-12-28 | The Upjohn Company | 4-Amino-cyclohexanols, their pharmaceutical compositions and methods of use |
FR2472559A1 (fr) * | 1979-12-31 | 1981-07-03 | Cerm Cent Europ Rech Mauvernay | Derives du 1-aminomethyl 2-phenoxy cyclohexanol, procede d'obtention, application en therapeutique et compositions les contenant |
US4391827A (en) * | 1980-09-08 | 1983-07-05 | Pfizer Inc. | 3-(2-Hydroxy-4-(substituted)phenyl)-cycloalkanone and cycloalkanol analgesic agents and intermediates therefor |
US4921994A (en) * | 1980-09-19 | 1990-05-01 | Pfizer Inc. | Pharmacologically active 2-hydroxy-4-(substituted) phenyl cycloalkanes and derivatives thereof |
US4593131A (en) * | 1980-09-19 | 1986-06-03 | Pfizer Inc. | Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor |
US4331602A (en) * | 1980-09-19 | 1982-05-25 | Pfizer Inc. | Pharmacologically active 4-[2-hydroxy-4-(substituted]phenyl)naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor |
US4486609A (en) * | 1981-03-16 | 1984-12-04 | Pfizer Inc. | Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor |
US4831059A (en) * | 1980-09-19 | 1989-05-16 | Pfizer Inc. | Producing analgesia with pharmacologically active 2-hydroxy-4-(substituted) phenyl cycloalkanes derivatives |
US4933475A (en) * | 1980-09-19 | 1990-06-12 | Pfizer, Inc. | Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor |
US4835192A (en) * | 1980-09-19 | 1989-05-30 | Pfizer Inc. | Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor |
US4285867A (en) * | 1980-09-19 | 1981-08-25 | Pfizer Inc. | Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor |
US4371720A (en) * | 1980-09-19 | 1983-02-01 | Pfizer Inc. | 2-Hydroxy-4-(substituted) phenyl cycloalkanes and derivatives |
US4739079A (en) * | 1980-09-19 | 1988-04-19 | Pfizer Inc. | Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor |
JPS57122041A (en) * | 1981-01-21 | 1982-07-29 | Suntory Ltd | Phenylclohexane derivative |
US4847414A (en) * | 1981-10-19 | 1989-07-11 | Hoechst-Roussel Pharmaceuticals, Inc. | 2'-substituted-spiro[benzofuran-2(3H),1'-cyclohexanes] and intermediates thereof |
US4535186A (en) * | 1983-04-19 | 1985-08-13 | American Home Products Corporation | 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives |
EP0134889B1 (en) * | 1983-08-19 | 1987-11-11 | Pennwalt Corporation | Cyclohexane carboxylic acids and derivatives thereof as antidysrhythmic agents |
GB8405112D0 (en) * | 1984-02-28 | 1984-04-04 | Akzo Nv | Anti-arrhythmic amino-alcohols |
US4760146A (en) * | 1986-02-18 | 1988-07-26 | Pennwalt Corporation | Cyclohexene carboxylic esters and amides as antidysrhythmic agents |
US5248830A (en) * | 1989-08-24 | 1993-09-28 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Enantioselective preparation of acetylenic or olefinic substituted cycloalkenyl dihydroxybutyrates and 4-hydroxy-tetrahydro-pyran-2-ones |
AU2023292A (en) * | 1991-02-11 | 1992-09-15 | Rhone-Poulenc Rorer International (Holdings) Inc. | Enantioselective preparation of acetylenic or olefinic substituted cycloalkenyl dihydroxybutyrates and 4-hydroxy-tetrahydropyran-2-ones |
NZ260408A (en) | 1993-05-10 | 1996-05-28 | Euro Celtique Sa | Controlled release preparation comprising tramadol |
KR100354702B1 (ko) * | 1993-11-23 | 2002-12-28 | 유로-셀티크 소시에떼 아노뉨 | 약학조성물의제조방법및서방형조성물 |
US5891471A (en) * | 1993-11-23 | 1999-04-06 | Euro-Celtique, S.A. | Pharmaceutical multiparticulates |
US5843480A (en) * | 1994-03-14 | 1998-12-01 | Euro-Celtique, S.A. | Controlled release diamorphine formulation |
GB9422154D0 (en) * | 1994-11-03 | 1994-12-21 | Euro Celtique Sa | Pharmaceutical compositions and method of producing the same |
US5965161A (en) | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
DE19918325A1 (de) | 1999-04-22 | 2000-10-26 | Euro Celtique Sa | Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion |
DE10000311A1 (de) * | 2000-01-05 | 2001-07-12 | Gruenenthal Gmbh | Aminomethyl-Phonyl-Cyclohexanonderivate |
DE10048714A1 (de) * | 2000-09-30 | 2002-04-11 | Gruenenthal Gmbh | 5-Amino-1-penlen-3-ol-Derivate |
MX2009012685A (es) | 2007-05-31 | 2009-12-14 | Sepracor Inc | Cicloalquilaminas sustituidas con fenilo como inhibidores de la reabsorcion de monoamina. |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2586512A (en) * | 1948-09-15 | 1952-02-19 | Searle & Co | Cyclohexyl-amino-alcohols |
US2680115A (en) * | 1949-01-28 | 1954-06-01 | Maurice L Tainter | Substituted tertiary-aminoalkyl carbinols |
US2656386A (en) * | 1951-02-24 | 1953-10-20 | Upjohn Co | Aminoethylhydrocarbonoxycyclohexenes |
US3652589A (en) * | 1967-07-27 | 1972-03-28 | Gruenenthal Chemie | 1-(m-substituted phenyl)-2-aminomethyl cyclohexanols |
-
1975
- 1975-01-29 US US05/545,074 patent/US3974157A/en not_active Expired - Lifetime
- 1975-02-28 FI FI750601A patent/FI60205C/fi not_active IP Right Cessation
- 1975-02-28 NL NL7502450A patent/NL7502450A/xx not_active Application Discontinuation
- 1975-03-03 NO NO750706A patent/NO140100C/no unknown
- 1975-03-03 DK DK83575A patent/DK143698C/da not_active IP Right Cessation
- 1975-03-04 CH CH270775A patent/CH621329A5/de not_active IP Right Cessation
- 1975-03-04 IE IE459/75A patent/IE40733B1/xx unknown
- 1975-03-04 LU LU71964A patent/LU71964A1/xx unknown
- 1975-03-04 FR FR7506772A patent/FR2262974B1/fr not_active Expired
- 1975-03-04 GB GB891575A patent/GB1474004A/en not_active Expired
- 1975-03-04 JP JP50025688A patent/JPS50157342A/ja active Pending
- 1975-03-04 BE BE153975A patent/BE826260A/xx not_active IP Right Cessation
- 1975-03-04 SE SE7502407A patent/SE7502407L/xx not_active Application Discontinuation
-
1978
- 1978-12-11 CH CH1260278A patent/CH615413A5/de not_active IP Right Cessation
- 1978-12-11 CH CH1260378A patent/CH617921A5/de not_active IP Right Cessation
-
1979
- 1979-07-13 CH CH657979A patent/CH619207A5/de not_active IP Right Cessation
- 1979-08-03 DK DK328479A patent/DK328479A/da not_active Application Discontinuation
-
1982
- 1982-05-14 SE SE8203051A patent/SE8203051L/sv not_active Application Discontinuation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10968209B2 (en) | 2016-05-19 | 2021-04-06 | Glaxosmithkline Intellectual Property (No.2) Limited | TRPV4 antagonist |
Also Published As
Publication number | Publication date |
---|---|
NO140100B (no) | 1979-03-26 |
NO140100C (no) | 1979-07-04 |
DK143698C (da) | 1982-03-08 |
GB1474004A (en) | 1977-05-18 |
AU7877375A (en) | 1976-09-09 |
CH619207A5 (en) | 1980-09-15 |
DK143698B (da) | 1981-09-28 |
IE40733L (en) | 1975-09-04 |
DK83575A (es) | 1975-09-05 |
LU71964A1 (es) | 1975-08-20 |
FI750601A (es) | 1975-09-05 |
NL7502450A (nl) | 1975-09-08 |
JPS50157342A (es) | 1975-12-19 |
CH617921A5 (en) | 1980-06-30 |
SE8203051L (sv) | 1982-05-14 |
US3974157A (en) | 1976-08-10 |
FR2262974B1 (es) | 1980-01-25 |
DK328479A (da) | 1979-08-03 |
CH621329A5 (es) | 1981-01-30 |
FI60205C (fi) | 1981-12-10 |
SE7502407L (es) | 1975-09-05 |
FI60205B (fi) | 1981-08-31 |
NO750706L (es) | 1975-09-05 |
IE40733B1 (en) | 1979-08-01 |
FR2262974A1 (es) | 1975-10-03 |
CH615413A5 (en) | 1980-01-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: PENNWALT CORP. Effective date: 19840304 |